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The map label for this gene is atpH [H]

Identifier: 225853246

GI number: 225853246

Start: 1749017

End: 1749577

Strand: Reverse

Name: atpH [H]

Synonym: BMEA_A1852

Alternate gene names: 225853246

Gene position: 1749577-1749017 (Counterclockwise)

Preceding gene: 225853247

Following gene: 225853245

Centisome position: 82.31

GC content: 58.47

Gene sequence:

>561_bases
GTGGCTGAAACGTCTTCGCTCATTTCTGGTGTCGCACAGCGTTGCGCCGGATCGCTTTTCGAGCTCGCGCTCGATGCGAA
TTCCGTCGCGTCTGTGGAAAAGGATCTTGGCCGCTTCGAGGCGCTTCTGAGCGGAAGCGAAGACCTCAGGCGTCTGATTT
CCAGTCCTGTGTTTTCTTCGGAAGACCAGCTTCACGCCATTGGCGCTATCGCCGACAAGGCTGGCATCAAGGGTCTGGTC
GGGAATTTCCTGCGCGTCGTCGCGCAGAACCGCCGTCTCTTTGCACTGCCGGGCATCATTGCCGCTTTCCGCCAGATTGC
TGCCGAACATCGCGGTGAGATTTCCGCCGATGTGGTTTCGGCGCACGAGCTGACGTCTGCGCAGCAGAACGAATTGAAGG
CGACGCTGAAGGGCGTGGCCGGCAAGGACGTGACGATCAACGTCACCGTCGATCCGTCGATCCTCGGCGGTCTTATCGTC
AAGATGGGTTCGCGTCAGATCGACACGTCCCTTCGCACCAAACTTTCTTCTCTTAAGCTTGCACTGAAAGAGGTCGGCTG
A

Upstream 100 bases:

>100_bases
TCAGGGGTTTTCCGAAAACATTCAATAAAATCATCGGTTTGGCGTCCTGAACGAGATTGGGTCCCAAAAGAGTGGTTTCA
ACGTAGAGAGCAGGTTGTTC

Downstream 100 bases:

>100_bases
TGGACATCCGCGCCGCGGAAATTTCCGCTATCCTGAAAGAGCAAATCAAGAACTTCGGCAAGGAGGCTGAGGTCTCCGAG
GTCGGTCAGGTTCTGTCCGT

Product: F0F1 ATP synthase subunit delta

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F(1) sector subunit delta; F-type ATPase subunit delta; F-ATPase subunit delta [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MAETSSLISGVAQRCAGSLFELALDANSVASVEKDLGRFEALLSGSEDLRRLISSPVFSSEDQLHAIGAIADKAGIKGLV
GNFLRVVAQNRRLFALPGIIAAFRQIAAEHRGEISADVVSAHELTSAQQNELKATLKGVAGKDVTINVTVDPSILGGLIV
KMGSRQIDTSLRTKLSSLKLALKEVG

Sequences:

>Translated_186_residues
MAETSSLISGVAQRCAGSLFELALDANSVASVEKDLGRFEALLSGSEDLRRLISSPVFSSEDQLHAIGAIADKAGIKGLV
GNFLRVVAQNRRLFALPGIIAAFRQIAAEHRGEISADVVSAHELTSAQQNELKATLKGVAGKDVTINVTVDPSILGGLIV
KMGSRQIDTSLRTKLSSLKLALKEVG
>Mature_185_residues
AETSSLISGVAQRCAGSLFELALDANSVASVEKDLGRFEALLSGSEDLRRLISSPVFSSEDQLHAIGAIADKAGIKGLVG
NFLRVVAQNRRLFALPGIIAAFRQIAAEHRGEISADVVSAHELTSAQQNELKATLKGVAGKDVTINVTVDPSILGGLIVK
MGSRQIDTSLRTKLSSLKLALKEVG

Specific function: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction [H]

COG id: COG0712

COG function: function code C; F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase delta chain family [H]

Homologues:

Organism=Homo sapiens, GI4502303, Length=180, Percent_Identity=31.1111111111111, Blast_Score=94, Evalue=6e-20,
Organism=Escherichia coli, GI1790173, Length=171, Percent_Identity=29.2397660818713, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71984710, Length=184, Percent_Identity=31.5217391304348, Blast_Score=103, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71984717, Length=184, Percent_Identity=31.5217391304348, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6320504, Length=180, Percent_Identity=27.7777777777778, Blast_Score=68, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24647054, Length=168, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24647056, Length=96, Percent_Identity=40.625, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000711
- InterPro:   IPR020781 [H]

Pfam domain/function: PF00213 OSCP [H]

EC number: 3.6.3.14

Molecular weight: Translated: 19564; Mature: 19433

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: PS00389 ATPASE_DELTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETSSLISGVAQRCAGSLFELALDANSVASVEKDLGRFEALLSGSEDLRRLISSPVFSS
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
EDQLHAIGAIADKAGIKGLVGNFLRVVAQNRRLFALPGIIAAFRQIAAEHRGEISADVVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHH
AHELTSAQQNELKATLKGVAGKDVTINVTVDPSILGGLIVKMGSRQIDTSLRTKLSSLKL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALKEVG
HHHHCC
>Mature Secondary Structure 
AETSSLISGVAQRCAGSLFELALDANSVASVEKDLGRFEALLSGSEDLRRLISSPVFSS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
EDQLHAIGAIADKAGIKGLVGNFLRVVAQNRRLFALPGIIAAFRQIAAEHRGEISADVVS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHH
AHELTSAQQNELKATLKGVAGKDVTINVTVDPSILGGLIVKMGSRQIDTSLRTKLSSLKL
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
ALKEVG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA