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The map label for this gene is ruvC

Identifier: 225853160

GI number: 225853160

Start: 1666125

End: 1666646

Strand: Reverse

Name: ruvC

Synonym: BMEA_A1757

Alternate gene names: 225853160

Gene position: 1666646-1666125 (Counterclockwise)

Preceding gene: 225853161

Following gene: 225853159

Centisome position: 78.4

GC content: 59.77

Gene sequence:

>522_bases
ATGAAAGAAACGATTCGCATTATTGGCATCGATCCGGGCCTGCGCCGAACCGGCTGGGGCATCGTCGAATCGCTTGGCAA
TTCGCTGCATTTCATCGGCTCGGGGACCGTGACCTCGAATGCCGAGATGGATCTGGCATCGCGCCTGTGCCAGTTGCATG
AAGGGCTTTCAAAAGTCCTGCATGAATTCATGCCGCATGAAGCGGCGGTCGAGCATACTTTCGTCAACAAGGACGCGACT
GCAACACTCAAACTGGGGCAGGCGCGCGGCATTGCGCTGCTGGCGCCGGCGCAGGCCGGATTGCCGGTTGCCGAATATGC
GCCCAATGCCGTCAAGAAGGCGGTGATCGGCGTTGGCCATGGCGAAAAGCAGCAGATCCACATGATGGTGAAGGTGCTGA
TGCCGCGCGCTTCCTTCGATACGAGCGATGCCGCCGATGCGCTGGCCATCGCCATATGTCATGCGCATCACCGGCAGAGC
ATCGTGAGTGCCCGCCGGATGCAGGCATTGTTAGCGGGGTAA

Upstream 100 bases:

>100_bases
AGGTTTCCGCGCTGCGTCGTGCCGGTTGCGCAGTGTATATGTTTCTCTTTTGTTCACTTTTCTGCTGTCAAGTGGACCCG
TCTGAGGATAGGGTTCGCTT

Downstream 100 bases:

>100_bases
TATCATGATCGGCAAGTTGAAGGGCGTGATTGACGAAATTGCCGAGGACCATGCTGTCATCGACGTGCATGGCGTGGGCT
ATGTCGCGTTTTGTTCGGCG

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKETIRIIGIDPGLRRTGWGIVESLGNSLHFIGSGTVTSNAEMDLASRLCQLHEGLSKVLHEFMPHEAAVEHTFVNKDAT
ATLKLGQARGIALLAPAQAGLPVAEYAPNAVKKAVIGVGHGEKQQIHMMVKVLMPRASFDTSDAADALAIAICHAHHRQS
IVSARRMQALLAG

Sequences:

>Translated_173_residues
MKETIRIIGIDPGLRRTGWGIVESLGNSLHFIGSGTVTSNAEMDLASRLCQLHEGLSKVLHEFMPHEAAVEHTFVNKDAT
ATLKLGQARGIALLAPAQAGLPVAEYAPNAVKKAVIGVGHGEKQQIHMMVKVLMPRASFDTSDAADALAIAICHAHHRQS
IVSARRMQALLAG
>Mature_173_residues
MKETIRIIGIDPGLRRTGWGIVESLGNSLHFIGSGTVTSNAEMDLASRLCQLHEGLSKVLHEFMPHEAAVEHTFVNKDAT
ATLKLGQARGIALLAPAQAGLPVAEYAPNAVKKAVIGVGHGEKQQIHMMVKVLMPRASFDTSDAADALAIAICHAHHRQS
IVSARRMQALLAG

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=128, Percent_Identity=42.96875, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_BRUA1 (B2S7E1)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935562.1
- ProteinModelPortal:   B2S7E1
- SMR:   B2S7E1
- GeneID:   6327552
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I16040
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- ProtClustDB:   PRK00039
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18456; Mature: 18456

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETIRIIGIDPGLRRTGWGIVESLGNSLHFIGSGTVTSNAEMDLASRLCQLHEGLSKVL
CCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
HEFMPHEAAVEHTFVNKDATATLKLGQARGIALLAPAQAGLPVAEYAPNAVKKAVIGVGH
HHHCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCHHHHCCHHHHHHHHCCCC
GEKQQIHMMVKVLMPRASFDTSDAADALAIAICHAHHRQSIVSARRMQALLAG
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKETIRIIGIDPGLRRTGWGIVESLGNSLHFIGSGTVTSNAEMDLASRLCQLHEGLSKVL
CCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
HEFMPHEAAVEHTFVNKDATATLKLGQARGIALLAPAQAGLPVAEYAPNAVKKAVIGVGH
HHHCCCHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCCCCCHHHHCCHHHHHHHHCCCC
GEKQQIHMMVKVLMPRASFDTSDAADALAIAICHAHHRQSIVSARRMQALLAG
CCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA