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The map label for this gene is ruvB [H]

Identifier: 225853158

GI number: 225853158

Start: 1664422

End: 1665462

Strand: Reverse

Name: ruvB [H]

Synonym: BMEA_A1755

Alternate gene names: 225853158

Gene position: 1665462-1664422 (Counterclockwise)

Preceding gene: 225853159

Following gene: 225853157

Centisome position: 78.35

GC content: 61.48

Gene sequence:

>1041_bases
ATGAGCGACCGTAACCCCCTGATCGATGCCGACCGGCGCGCAGACGAAGACAATACGCTGCGCCCGCAGACGCTTGACGA
TTTTGTGGGCCAAGCGGCGGCGCGCGCCAATCTGAAAGTGTTTATTGAAGCCGCCAAGGTGCGTGGCGAGGCGCTGGATC
ATGTGCTTTTCGTCGGCCCGCCCGGCCTCGGCAAGACGACGCTGGCGCAGATCATGGCGAAAGAACTTGGCGTCAATTTC
CGCTCCACATCCGGCCCGGTCATCGCCAAGGCAGGCGATCTCGCCGCGCTGCTTACCAATCTGGAAGAGCGCGACGTGTT
GTTCATCGATGAAATCCATCGCCTGAGCCCCGCGGTGGAAGAAATTCTCTATCCGGCCATGGAGGATTTTCAGCTCGATC
TCATCATCGGCGAGGGGCCTGCCGCGCGTTCGGTCAAGATCGACCTCGCCAAGTTTACGCTTGTTGCCGCCACGACGCGC
CTTGGCCTGCTCACCACGCCCCTGCGCGACCGGTTCGGCATTCCGGTGCGGCTCAATTTCTATACGGTCGAAGAGCTGGA
ATATATTGTGCGGCGCGGCGCGCGCATCATGCAGATGGGAATCTCGTCTGACGGCGCGCGGGAAGTTGCCCGCCGTTCGC
GCGGCACGCCGCGTATTGTCGGGCGGCTTTTGCGGCGCGTGCGCGATTTCGCGCTGGTCGCGGGCGCGGATATCATAGAC
CGCAGAATAGCCGATGAGGCGCTGTCGCGGCTTGAGGTGGACAATCGCGGCCTCGACCAGCTTGACCGGCGCTATCTCAA
TATTATTGCGCGCAATTTTGGCGGTGGGCCGGTCGGGATCGAAACCATTGCGGCGGGCTTGTCCGAGCCGCGCGATGCGA
TTGAAGACATTATCGAACCCTATCTGATCCAGCAGGGTTTCCTGCAACGCACGCCGCGCGGGCGCGTGCTGACTGCCGTT
GCGTGGCAACATCTGGGATTACCTGCGCCTGCTGAAATCATCCAGCAGTCGCAATATGGCCTCTTCATGGAAGACGAATG
A

Upstream 100 bases:

>100_bases
GGCGAGGGCGCCGATTCGGCCAAGCTGATACGGCTCGGTTTGAAGGAACTCTCGCAGTGATTTACTTGTCTGAACATGAG
CTTCATGCGAGGAGAGGGGC

Downstream 100 bases:

>100_bases
CCGACAAGCAGCAACAGGCCGTATCCGGCGAACTCAAAGACGGCGCGCATCTGCTTTATGCGCGCATCTATTATGCCGAT
ACGGATTTTTCCGGCTTTGT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNF
RSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTR
LGLLTTPLRDRFGIPVRLNFYTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIVGRLLRRVRDFALVAGADIID
RRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFLQRTPRGRVLTAV
AWQHLGLPAPAEIIQQSQYGLFMEDE

Sequences:

>Translated_346_residues
MSDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNF
RSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTR
LGLLTTPLRDRFGIPVRLNFYTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIVGRLLRRVRDFALVAGADIID
RRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFLQRTPRGRVLTAV
AWQHLGLPAPAEIIQQSQYGLFMEDE
>Mature_345_residues
SDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNFR
STSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTRL
GLLTTPLRDRFGIPVRLNFYTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIVGRLLRRVRDFALVAGADIIDR
RIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFLQRTPRGRVLTAVA
WQHLGLPAPAEIIQQSQYGLFMEDE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=314, Percent_Identity=63.6942675159236, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000641
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 38270; Mature: 38138

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGP
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHHCEEEEECC
PGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVE
CCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPVRLNF
HHHHHHHHCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEE
YTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIVGRLLRRVRDFALVAGADIID
EEHHHHHHHHHCCCCEEHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHH
RRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHH
YLIQQGFLQRTPRGRVLTAVAWQHLGLPAPAEIIQQSQYGLFMEDE
HHHHHHHHHCCCCCCEEHHHHHHHCCCCCCHHHHHHHCCCCEEECC
>Mature Secondary Structure 
SDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHHCEEEEECC
PGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVE
CCCCHHHHHHHHHHHHCCCEECCCCCEEECCCHHHHHHHCCCCCCEEHHHHHHHHHHHHH
EILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPVRLNF
HHHHHHHHCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEE
YTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIVGRLLRRVRDFALVAGADIID
EEHHHHHHHHHCCCCEEHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHH
RRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHH
YLIQQGFLQRTPRGRVLTAVAWQHLGLPAPAEIIQQSQYGLFMEDE
HHHHHHHHHCCCCCCEEHHHHHHHCCCCCCHHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA