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The map label for this gene is fur [H]

Identifier: 225853120

GI number: 225853120

Start: 1623243

End: 1623668

Strand: Direct

Name: fur [H]

Synonym: BMEA_A1711

Alternate gene names: 225853120

Gene position: 1623243-1623668 (Clockwise)

Preceding gene: 225853119

Following gene: 225853124

Centisome position: 76.36

GC content: 52.82

Gene sequence:

>426_bases
ATGAACAAGCCATACACCAAACCGGATTATGAGCAGGAGCTGAGGCGGGCTGGCGTTCGTATTACACGTCCGCGGCGGAT
CATCCTGAACATATTGAACGAAACTGAAGACCACCCGGACGCACTGGAGATTTTCCGGCGTGCGGTGGAAGAGGACGACA
GTATCTCGCTTTCAACGGTTTATCACACCATGAAACTTCTTGAGGAACGCGGCGCGATCCATCGCCATGCCTTTGCGGGC
GGGCCGTCGCGCTTCGAGCAGGCCAGCGGTGCGCATCATGACCATATCATTGATATGGATTCTGGTGATGTGGTGGAGTT
CCACTCCGACAAGATCGAAAAATTGCAGGAAGAGATCGCGCGTTCGCTCGGCTTCGAGATCGTTCATCACCGGCTTGAAC
TTTATTGCAAAAAATTGAAATCCTGA

Upstream 100 bases:

>100_bases
ATCATCCCGAAACAGGCGTGCCCAAAAAGCTTTTGGGGAGATTGGGTTCTTTCAGTTGCAAAAAATTGCAACTGATGGCG
ATGCAGTGCATAATCGATCC

Downstream 100 bases:

>100_bases
CGGAACCAATCCAGGAAGTTGGCGTTTTACGGATATGACGACCGTGACCCCGCCCCCACAACACGGTCTTCAGAGTTCGC
TTCAAAACCTCCCCGCACGA

Product: ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MNKPYTKPDYEQELRRAGVRITRPRRIILNILNETEDHPDALEIFRRAVEEDDSISLSTVYHTMKLLEERGAIHRHAFAG
GPSRFEQASGAHHDHIIDMDSGDVVEFHSDKIEKLQEEIARSLGFEIVHHRLELYCKKLKS

Sequences:

>Translated_141_residues
MNKPYTKPDYEQELRRAGVRITRPRRIILNILNETEDHPDALEIFRRAVEEDDSISLSTVYHTMKLLEERGAIHRHAFAG
GPSRFEQASGAHHDHIIDMDSGDVVEFHSDKIEKLQEEIARSLGFEIVHHRLELYCKKLKS
>Mature_141_residues
MNKPYTKPDYEQELRRAGVRITRPRRIILNILNETEDHPDALEIFRRAVEEDDSISLSTVYHTMKLLEERGAIHRHAFAG
GPSRFEQASGAHHDHIIDMDSGDVVEFHSDKIEKLQEEIARSLGFEIVHHRLELYCKKLKS

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=129, Percent_Identity=38.7596899224806, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16399; Mature: 16399

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPYTKPDYEQELRRAGVRITRPRRIILNILNETEDHPDALEIFRRAVEEDDSISLSTV
CCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHH
YHTMKLLEERGAIHRHAFAGGPSRFEQASGAHHDHIIDMDSGDVVEFHSDKIEKLQEEIA
HHHHHHHHHHCHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHH
RSLGFEIVHHRLELYCKKLKS
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKPYTKPDYEQELRRAGVRITRPRRIILNILNETEDHPDALEIFRRAVEEDDSISLSTV
CCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHH
YHTMKLLEERGAIHRHAFAGGPSRFEQASGAHHDHIIDMDSGDVVEFHSDKIEKLQEEIA
HHHHHHHHHHCHHHHHHHCCCHHHHHHHCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHH
RSLGFEIVHHRLELYCKKLKS
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA