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The map label for this gene is aatA [H]

Identifier: 225852975

GI number: 225852975

Start: 1471977

End: 1473179

Strand: Direct

Name: aatA [H]

Synonym: BMEA_A1547

Alternate gene names: 225852975

Gene position: 1471977-1473179 (Clockwise)

Preceding gene: 225852973

Following gene: 225852976

Centisome position: 69.25

GC content: 58.27

Gene sequence:

>1203_bases
ATGGCATTTCTCGCCGACGCCCTTTCCCGTGTAAAGCCATCTGCGACCATCGCTGTCAGCCAGAAAGCACGTGAACTGAA
AGCAAAAGGCAAGGACGTGATCGTCCTGGGCGCAGGTGAGCCGGATTTCGACACGCCTGAAAATATCAAGCAGGCGGCCA
TTGCCGCGATCAATCGCGGTGAAACAAAGTACACGCCCGTATCCGGCATCCCGCAACTGCGCCAGGCCATCGTCTCCAAG
TTCAAGCGTGAAAACGGCCTCGACTACAAGCCGGAACAAACCATCGTCGGCACCGGCGGCAAGCAGATTTTGTTCAACGC
CTTCATGGCCACGCTGAACCCCGGCGACGAAGTCATCATTGCCGCCCCCTATTGGGTCAGCTACCCGGAAATGGTGGCCA
TCAACGGCGGCACCCCGGTTTTCGTCGACACGAAGATTGAAGACAATTTCAAGCTGACCGCTGCCGATCTCGAAAAGGCG
ATCACACCGAAGACCAAGTGGCTCATCTTCAACTCGCCCTCCAACCCGACCGGCGCGGCCTATACGCAAGCCGAACTGAA
GTCGCTGACCGACGTTCTCGTGCGCCATCCGCATGTCTGGATCTTGACCGACGACATGTATGAGCATCTGGTCTATGGCG
ATTTCGTCTTCACGACGCCTGCTCAGGTGGAACCCTCGCTCTATGACCGTACGCTCACCATGAACGGCGTTTCCAAGGCC
TATGCCATGACCGGCTGGCGCATCGGCTATGCCGCCGGTCCAATCGAGCTCATCAAGGCCATGGACATGATTCAGGGGCA
GCAGACCTCCGGCGCCTGCTCGATTGCTCAGTGGGCAGCGGTCGAAGCACTGAACGGCACGCAGGATTTCATCCCCGCGA
ACAAGAAAATCTTCCAGGCCCGCCGCGATCTGGTCGTTTCCATGCTCAACCAGGCAACCGGCCTCCAGTGCCCGACGCCG
GAAGGCGCGTTCTATGTCTATCCGTCCTGCGCAGGGCTGATCGGCAAGAAGACCGAAGCGGGCAAAGTCATCGAAACCGA
CAAAGATTTTGTGACGGAACTTCTGGAAACCGAAGGCGTGGCGGTTGTTCATGGTTCGGCATTCGGCCTCGGCCCGAACT
TCCGCATTTCCTATGCAACCTCGGATGAGCTGCTGGAAAAAGCCTGCATACGCATCCAGCGTTTCTGCGCCAGCCTGCGC
TGA

Upstream 100 bases:

>100_bases
CTGTAGTTGCGCTTCTTGCGCCAATGCGACATAGAAAATGCGCAAAACCGGACCACGCCCGGTGACGGTTAACAGAGCCT
GCCATCTATGGAGATCTATC

Downstream 100 bases:

>100_bases
TATCAATATCAGCAGAAAAATGACCAAGGGGCCGCAAGGCCCCTTTTTCATATTCATCATTCAGGAATGGACAACCGGGC
AAAAGCCAAAAAAAAGCCAG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MAFLADALSRVKPSATIAVSQKARELKAKGKDVIVLGAGEPDFDTPENIKQAAIAAINRGETKYTPVSGIPQLRQAIVSK
FKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVIIAAPYWVSYPEMVAINGGTPVFVDTKIEDNFKLTAADLEKA
ITPKTKWLIFNSPSNPTGAAYTQAELKSLTDVLVRHPHVWILTDDMYEHLVYGDFVFTTPAQVEPSLYDRTLTMNGVSKA
YAMTGWRIGYAAGPIELIKAMDMIQGQQTSGACSIAQWAAVEALNGTQDFIPANKKIFQARRDLVVSMLNQATGLQCPTP
EGAFYVYPSCAGLIGKKTEAGKVIETDKDFVTELLETEGVAVVHGSAFGLGPNFRISYATSDELLEKACIRIQRFCASLR

Sequences:

>Translated_400_residues
MAFLADALSRVKPSATIAVSQKARELKAKGKDVIVLGAGEPDFDTPENIKQAAIAAINRGETKYTPVSGIPQLRQAIVSK
FKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVIIAAPYWVSYPEMVAINGGTPVFVDTKIEDNFKLTAADLEKA
ITPKTKWLIFNSPSNPTGAAYTQAELKSLTDVLVRHPHVWILTDDMYEHLVYGDFVFTTPAQVEPSLYDRTLTMNGVSKA
YAMTGWRIGYAAGPIELIKAMDMIQGQQTSGACSIAQWAAVEALNGTQDFIPANKKIFQARRDLVVSMLNQATGLQCPTP
EGAFYVYPSCAGLIGKKTEAGKVIETDKDFVTELLETEGVAVVHGSAFGLGPNFRISYATSDELLEKACIRIQRFCASLR
>Mature_399_residues
AFLADALSRVKPSATIAVSQKARELKAKGKDVIVLGAGEPDFDTPENIKQAAIAAINRGETKYTPVSGIPQLRQAIVSKF
KRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVIIAAPYWVSYPEMVAINGGTPVFVDTKIEDNFKLTAADLEKAI
TPKTKWLIFNSPSNPTGAAYTQAELKSLTDVLVRHPHVWILTDDMYEHLVYGDFVFTTPAQVEPSLYDRTLTMNGVSKAY
AMTGWRIGYAAGPIELIKAMDMIQGQQTSGACSIAQWAAVEALNGTQDFIPANKKIFQARRDLVVSMLNQATGLQCPTPE
GAFYVYPSCAGLIGKKTEAGKVIETDKDFVTELLETEGVAVVHGSAFGLGPNFRISYATSDELLEKACIRIQRFCASLR

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=357, Percent_Identity=28.2913165266106, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI95147551, Length=369, Percent_Identity=28.4552845528455, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI169881279, Length=369, Percent_Identity=28.4552845528455, Blast_Score=145, Evalue=5e-35,
Organism=Homo sapiens, GI56713256, Length=357, Percent_Identity=28.2913165266106, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4507369, Length=385, Percent_Identity=26.2337662337662, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI169881281, Length=335, Percent_Identity=24.4776119402985, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1788627, Length=394, Percent_Identity=26.9035532994924, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786816, Length=380, Percent_Identity=25.7894736842105, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1788722, Length=352, Percent_Identity=30.6818181818182, Blast_Score=125, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71994472, Length=392, Percent_Identity=27.5510204081633, Blast_Score=121, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71994476, Length=392, Percent_Identity=27.5510204081633, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=24.5382585751979, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=324, Percent_Identity=27.1604938271605, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=399, Percent_Identity=27.0676691729323, Blast_Score=129, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=346, Percent_Identity=22.8323699421965, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573069, Length=384, Percent_Identity=27.8645833333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24646114, Length=384, Percent_Identity=27.8645833333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573067, Length=384, Percent_Identity=27.8645833333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573065, Length=384, Percent_Identity=27.8645833333333, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859735, Length=379, Percent_Identity=23.7467018469657, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI45551451, Length=373, Percent_Identity=27.0777479892761, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24641770, Length=373, Percent_Identity=27.0777479892761, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641760, Length=373, Percent_Identity=27.0777479892761, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641768, Length=373, Percent_Identity=27.0777479892761, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641766, Length=373, Percent_Identity=27.0777479892761, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641764, Length=373, Percent_Identity=27.0777479892761, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43528; Mature: 43397

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFLADALSRVKPSATIAVSQKARELKAKGKDVIVLGAGEPDFDTPENIKQAAIAAINRG
CCHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCC
ETKYTPVSGIPQLRQAIVSKFKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVII
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEE
AAPYWVSYPEMVAINGGTPVFVDTKIEDNFKLTAADLEKAITPKTKWLIFNSPSNPTGAA
ECCCEECCCCEEEECCCCEEEEEEEECCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCH
YTQAELKSLTDVLVRHPHVWILTDDMYEHLVYGDFVFTTPAQVEPSLYDRTLTMNGVSKA
HHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCEEEECCCCCCCCHHHCEEEECCCHHH
YAMTGWRIGYAAGPIELIKAMDMIQGQQTSGACSIAQWAAVEALNGTQDFIPANKKIFQA
HHHCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCHHHHHH
RRDLVVSMLNQATGLQCPTPEGAFYVYPSCAGLIGKKTEAGKVIETDKDFVTELLETEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHCCCCCCCCCEEECCHHHHHHHHHCCCE
AVVHGSAFGLGPNFRISYATSDELLEKACIRIQRFCASLR
EEEECCEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFLADALSRVKPSATIAVSQKARELKAKGKDVIVLGAGEPDFDTPENIKQAAIAAINRG
CHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCC
ETKYTPVSGIPQLRQAIVSKFKRENGLDYKPEQTIVGTGGKQILFNAFMATLNPGDEVII
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEE
AAPYWVSYPEMVAINGGTPVFVDTKIEDNFKLTAADLEKAITPKTKWLIFNSPSNPTGAA
ECCCEECCCCEEEECCCCEEEEEEEECCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCH
YTQAELKSLTDVLVRHPHVWILTDDMYEHLVYGDFVFTTPAQVEPSLYDRTLTMNGVSKA
HHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHCCEEEECCCCCCCCHHHCEEEECCCHHH
YAMTGWRIGYAAGPIELIKAMDMIQGQQTSGACSIAQWAAVEALNGTQDFIPANKKIFQA
HHHCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCHHHHHH
RRDLVVSMLNQATGLQCPTPEGAFYVYPSCAGLIGKKTEAGKVIETDKDFVTELLETEGV
HHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHCCCCCCCCCEEECCHHHHHHHHHCCCE
AVVHGSAFGLGPNFRISYATSDELLEKACIRIQRFCASLR
EEEECCEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]