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The map label for this gene is hflK [H]

Identifier: 225852879

GI number: 225852879

Start: 1371456

End: 1372658

Strand: Reverse

Name: hflK [H]

Synonym: BMEA_A1444

Alternate gene names: 225852879

Gene position: 1372658-1371456 (Counterclockwise)

Preceding gene: 225852880

Following gene: 225852878

Centisome position: 64.57

GC content: 58.94

Gene sequence:

>1203_bases
ATGACGGAAGGCCAAGCTTGCTTTTCGTCACCCGGACGAGAGGTGAGGATGCCCTGGAGCAATCAGAATGGCGGCGGCGG
CCCGTGGGGCGGCGGCGGCGATAACAACAACAATAATAATAATGGACCTTGGGGGCAGGGGCCAAAGGGGCCGCGTGGCG
GCGGCCAGAACACGCCGCCCGACCTTGAAGATATTCTGCGCAAAGGGCAGGATCGGTTGAAGCAGGTTTTCCCCGGTGGC
GGTGGCCGAAAGGGCAGCAACCGCCCGATCTATTTCCTCATTGGCGCGGCAGTATTGGGTTTCTGGCTGTTCCAGTCGGT
CTATACAGTCCAGCCGGACGAACTCGCCGTGGAGCTGCGCTTCGGCAAGCCGAAGGAAGAGGTTTCCGAACCGGGCCTGC
ACTTCCATTGGTGGCCGTTCGAGACCTATGAAAAGGCGCAGATCGTCGAAAAGCAGATCAATATCGGCGGGCAGGGTACG
CGCAATGCGACGCAGGGCCTGATGCTGACGGGTGATCAGAACATCGTCAACGTGCAGTTCTCGGTGCTTTACCGTGTTTC
CGATCCGCGCGCCTATCTCTTCAATGTGGATAGCCCTGACGCGATGGTGCAGCAGGTTTCCGAAAGCGCGATCCGCGAGA
TCGTCGGTCGCCGTCCGGCACAGGATGTTTTCCGCGACAATCGCTCGGCCATTGCCCAGAGCGTGCGCGATATCGTTCAG
CAGACGCTCGACAATTACAAGGCCGGCATCCAGATCAATGCCGTTTCGATTGAAGATGCGGCCCCCCCGCGTGAAGTGGC
CGATGCATTTGACGAAGTTCAGCGTGCCGAACAGGACGAGGACCGCTTCGTGGAAGAATCGAACCAGTATTCCAACCAGA
AGCTGGGTCAGGCGCGCGGTGAAGCGGCGCAGCTTCGTGAAGAAGCCGCCGCTTACAAGAACCGTGTCGTTCAGGACGCT
GAAGGTGAAGCCCAGCGCTTCAGTTCGGTGCTGAAAGAGTATCAGAAGGCCCCGGAAGTCACCCGTAACCGTCTCTTCCT
TGAAACCATGGAAGAGGTGCTGAAGGGCACCAAGAAGGTCATTGTCGAACCCGGCAAGGATGTAGTGCCTTATCTGCCGC
TGCATGAATTGATGCAGAAGCAGCCGAGCACCGGCGTAAAGGCCCCCACCACGACGACCACCACTGGCGGAGGTAATCAG
TAA

Upstream 100 bases:

>100_bases
CTGTACGAAAGGCGCGTTTCGTAAAGCATAGGACAGGAATTTTGCCGCCTTTGCGTTGAAAGCGGCCCTCGCGATGCCTA
TAAAACGGAAACATTAGTTG

Downstream 100 bases:

>100_bases
TGACCCAGAACAGGCTCCCGATCATTGTCGGCTTCATTGCCGTCATCGCTTTCCTGCTCTATTCCTCCGTGTTCATCGTG
ACCGAACGCCAGCAGGCTAT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTEGQACFSSPGREVRMPWSNQNGGGGPWGGGGDNNNNNNNGPWGQGPKGPRGGGQNTPPDLEDILRKGQDRLKQVFPGG
GGRKGSNRPIYFLIGAAVLGFWLFQSVYTVQPDELAVELRFGKPKEEVSEPGLHFHWWPFETYEKAQIVEKQINIGGQGT
RNATQGLMLTGDQNIVNVQFSVLYRVSDPRAYLFNVDSPDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQ
QTLDNYKAGIQINAVSIEDAAPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARGEAAQLREEAAAYKNRVVQDA
EGEAQRFSSVLKEYQKAPEVTRNRLFLETMEEVLKGTKKVIVEPGKDVVPYLPLHELMQKQPSTGVKAPTTTTTTGGGNQ

Sequences:

>Translated_400_residues
MTEGQACFSSPGREVRMPWSNQNGGGGPWGGGGDNNNNNNNGPWGQGPKGPRGGGQNTPPDLEDILRKGQDRLKQVFPGG
GGRKGSNRPIYFLIGAAVLGFWLFQSVYTVQPDELAVELRFGKPKEEVSEPGLHFHWWPFETYEKAQIVEKQINIGGQGT
RNATQGLMLTGDQNIVNVQFSVLYRVSDPRAYLFNVDSPDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQ
QTLDNYKAGIQINAVSIEDAAPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARGEAAQLREEAAAYKNRVVQDA
EGEAQRFSSVLKEYQKAPEVTRNRLFLETMEEVLKGTKKVIVEPGKDVVPYLPLHELMQKQPSTGVKAPTTTTTTGGGNQ
>Mature_399_residues
TEGQACFSSPGREVRMPWSNQNGGGGPWGGGGDNNNNNNNGPWGQGPKGPRGGGQNTPPDLEDILRKGQDRLKQVFPGGG
GRKGSNRPIYFLIGAAVLGFWLFQSVYTVQPDELAVELRFGKPKEEVSEPGLHFHWWPFETYEKAQIVEKQINIGGQGTR
NATQGLMLTGDQNIVNVQFSVLYRVSDPRAYLFNVDSPDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQQ
TLDNYKAGIQINAVSIEDAAPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARGEAAQLREEAAAYKNRVVQDAE
GEAQRFSSVLKEYQKAPEVTRNRLFLETMEEVLKGTKKVIVEPGKDVVPYLPLHELMQKQPSTGVKAPTTTTTTGGGNQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=405, Percent_Identity=33.8271604938272, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 44162; Mature: 44030

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGQACFSSPGREVRMPWSNQNGGGGPWGGGGDNNNNNNNGPWGQGPKGPRGGGQNTPP
CCCCCCHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DLEDILRKGQDRLKQVFPGGGGRKGSNRPIYFLIGAAVLGFWLFQSVYTVQPDELAVELR
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHEEEEEE
FGKPKEEVSEPGLHFHWWPFETYEKAQIVEKQINIGGQGTRNATQGLMLTGDQNIVNVQF
CCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHCCEEEECCCCEEEEEE
SVLYRVSDPRAYLFNVDSPDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQ
EEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHH
QTLDNYKAGIQINAVSIEDAAPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARG
HHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
EAAQLREEAAAYKNRVVQDAEGEAQRFSSVLKEYQKAPEVTRNRLFLETMEEVLKGTKKV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHE
IVEPGKDVVPYLPLHELMQKQPSTGVKAPTTTTTTGGGNQ
EECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEGQACFSSPGREVRMPWSNQNGGGGPWGGGGDNNNNNNNGPWGQGPKGPRGGGQNTPP
CCCCCHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DLEDILRKGQDRLKQVFPGGGGRKGSNRPIYFLIGAAVLGFWLFQSVYTVQPDELAVELR
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCHHEEEEEE
FGKPKEEVSEPGLHFHWWPFETYEKAQIVEKQINIGGQGTRNATQGLMLTGDQNIVNVQF
CCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCHHCCEEEECCCCEEEEEE
SVLYRVSDPRAYLFNVDSPDAMVQQVSESAIREIVGRRPAQDVFRDNRSAIAQSVRDIVQ
EEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHH
QTLDNYKAGIQINAVSIEDAAPPREVADAFDEVQRAEQDEDRFVEESNQYSNQKLGQARG
HHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
EAAQLREEAAAYKNRVVQDAEGEAQRFSSVLKEYQKAPEVTRNRLFLETMEEVLKGTKKV
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHE
IVEPGKDVVPYLPLHELMQKQPSTGVKAPTTTTTTGGGNQ
EECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]