| Definition | Brucella melitensis ATCC 23457 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_012441 |
| Length | 2,125,701 |
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The map label for this gene is ucpA [C]
Identifier: 225852824
GI number: 225852824
Start: 1319116
End: 1319925
Strand: Reverse
Name: ucpA [C]
Synonym: BMEA_A1386
Alternate gene names: 225852824
Gene position: 1319925-1319116 (Counterclockwise)
Preceding gene: 225852825
Following gene: 225852823
Centisome position: 62.09
GC content: 59.01
Gene sequence:
>810_bases ATGGGCGGACAGTTGAAGGGTAAGATTGCAGTCATTACAGGCAGCACGCAGGGGCTGGGCGCGGCCACCGCCCGGCTGTT TGCCGAACGGGGCGCGCAAGGCCTTGTGATCTGCGGGCGTTCTGCCGAAAAGGGCAGGGCGCAGGCTGCCGGGCTTGAAG AACTGGGCGCAAAAGCGGTTTTCGTGCAGGTGGACCTTGAAAATGTGGAAGACTGCCGCCGCATCGTTGCAGAAGCTGAC CGGGCATTCGGCAGGCTTGATATTCTGGTGAATGCGGCGGGACTGACCGATCGCGGCACTATTCTGGATACATCACCGGA ACTGTTCGACCGGCTCTTTGCCGTGAACACGCGCGCGCCGTTTTTCCTTATTCAGGAAGCGATCAAGCTTTTCCGCCGTG ACAGGGTGGAGGGTGCGATTGTGAATGTCTCCTCCATGTCGTCCATGGGAGGCCAGCCTTTTATTGCAGCCTATTGCGCC TCCAAGGGCGCGCTCGACACGCTGACGCGCAATGTTGCCTATTCGGTTCTTCGCAACCGCATTCGGGTCAACAGCCTCAA TATCGGCTGGATGGCATCCGATGGCGAGGATCGTATCCAGCGTGAATATCATGGTGCACCGGCAAACTGGCTGGAGGAAG CCGTAAAGACGCAACCTTTCGGGCGGCTTCTCGACCCGGCGAAAGTGGCGCGCGCCATTGCTTTTCTGGCCTCGGAGGAA TCAGGACTGATGACGGGTGCTATCGTCAATTTCGACCAGTCGGTCTGGGGCGCTTATGACGGTTCTCCGCATCCTGAGAA GCCGCTTTGA
Upstream 100 bases:
>100_bases ATGTGGATATGGATGAGTTGCAAAGCCTGATGGCAGGCGGGCAGGAGCTTGCCGATCTTACCGCTGAACTGGGCGGGCGA GTATAACCGGAGAACATGGA
Downstream 100 bases:
>100_bases ACACTTGGCGATAGCGATTTTCCTTATTTGCATATCGGGGCCGCCTTGCGATAGGCTCGTACCGATAGATCATCGCTCTT TGGAAAAGAATTCATGCTCA
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 269; Mature: 268
Protein sequence:
>269_residues MGGQLKGKIAVITGSTQGLGAATARLFAERGAQGLVICGRSAEKGRAQAAGLEELGAKAVFVQVDLENVEDCRRIVAEAD RAFGRLDILVNAAGLTDRGTILDTSPELFDRLFAVNTRAPFFLIQEAIKLFRRDRVEGAIVNVSSMSSMGGQPFIAAYCA SKGALDTLTRNVAYSVLRNRIRVNSLNIGWMASDGEDRIQREYHGAPANWLEEAVKTQPFGRLLDPAKVARAIAFLASEE SGLMTGAIVNFDQSVWGAYDGSPHPEKPL
Sequences:
>Translated_269_residues MGGQLKGKIAVITGSTQGLGAATARLFAERGAQGLVICGRSAEKGRAQAAGLEELGAKAVFVQVDLENVEDCRRIVAEAD RAFGRLDILVNAAGLTDRGTILDTSPELFDRLFAVNTRAPFFLIQEAIKLFRRDRVEGAIVNVSSMSSMGGQPFIAAYCA SKGALDTLTRNVAYSVLRNRIRVNSLNIGWMASDGEDRIQREYHGAPANWLEEAVKTQPFGRLLDPAKVARAIAFLASEE SGLMTGAIVNFDQSVWGAYDGSPHPEKPL >Mature_268_residues GGQLKGKIAVITGSTQGLGAATARLFAERGAQGLVICGRSAEKGRAQAAGLEELGAKAVFVQVDLENVEDCRRIVAEADR AFGRLDILVNAAGLTDRGTILDTSPELFDRLFAVNTRAPFFLIQEAIKLFRRDRVEGAIVNVSSMSSMGGQPFIAAYCAS KGALDTLTRNVAYSVLRNRIRVNSLNIGWMASDGEDRIQREYHGAPANWLEEAVKTQPFGRLLDPAKVARAIAFLASEES GLMTGAIVNFDQSVWGAYDGSPHPEKPL
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=30.3643724696356, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=30.3643724696356, Blast_Score=97, Evalue=2e-20, Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI7705925, Length=254, Percent_Identity=29.5275590551181, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=28.7937743190661, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI59889578, Length=216, Percent_Identity=31.9444444444444, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI33667109, Length=204, Percent_Identity=31.3725490196078, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI20149619, Length=199, Percent_Identity=32.6633165829146, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=29.296875, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI4758504, Length=263, Percent_Identity=29.277566539924, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI126723191, Length=185, Percent_Identity=30.2702702702703, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI66933014, Length=252, Percent_Identity=30.952380952381, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI126723750, Length=251, Percent_Identity=27.8884462151394, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI83715985, Length=263, Percent_Identity=28.8973384030418, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI31542939, Length=274, Percent_Identity=24.0875912408759, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI210032110, Length=159, Percent_Identity=32.0754716981132, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=23.1372549019608, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=26.4, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=31.6326530612245, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI142976729, Length=216, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI32455239, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI5031765, Length=201, Percent_Identity=28.8557213930348, Blast_Score=69, Evalue=6e-12, Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=33.739837398374, Blast_Score=103, Evalue=9e-24, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=29.8387096774194, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI1789378, Length=257, Percent_Identity=32.6848249027237, Blast_Score=100, Evalue=9e-23, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=29.8387096774194, Blast_Score=99, Evalue=2e-22, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=31.4741035856574, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI87082160, Length=255, Percent_Identity=30.5882352941176, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=30.1204819277108, Blast_Score=88, Evalue=6e-19, Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=26.9709543568465, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=28.0632411067194, Blast_Score=87, Evalue=2e-18, Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1787526, Length=189, Percent_Identity=30.1587301587302, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=26.8774703557312, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1789057, Length=249, Percent_Identity=26.9076305220884, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71994600, Length=250, Percent_Identity=33.6, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=32.2834645669291, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI193204405, Length=251, Percent_Identity=34.2629482071713, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17560220, Length=249, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562906, Length=244, Percent_Identity=32.3770491803279, Blast_Score=107, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17562908, Length=252, Percent_Identity=32.9365079365079, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17559104, Length=250, Percent_Identity=34, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI17563726, Length=242, Percent_Identity=32.6446280991736, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562910, Length=259, Percent_Identity=30.8880308880309, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17531453, Length=244, Percent_Identity=32.3770491803279, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=33.7254901960784, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17544670, Length=256, Percent_Identity=29.296875, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=30.3501945525292, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562990, Length=244, Percent_Identity=32.7868852459016, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=30.6513409961686, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=28.6821705426357, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=28.5140562248996, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17560332, Length=247, Percent_Identity=31.5789473684211, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17560150, Length=247, Percent_Identity=30.3643724696356, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562904, Length=252, Percent_Identity=30.5555555555556, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=27.8225806451613, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI115534694, Length=249, Percent_Identity=28.1124497991968, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17508651, Length=239, Percent_Identity=27.1966527196653, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=25.3968253968254, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=26.8774703557312, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17564282, Length=180, Percent_Identity=30, Blast_Score=78, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=27.6422764227642, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=28.030303030303, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17538486, Length=194, Percent_Identity=29.3814432989691, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193203117, Length=159, Percent_Identity=31.4465408805031, Blast_Score=71, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17555612, Length=221, Percent_Identity=29.8642533936652, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI193203115, Length=158, Percent_Identity=31.6455696202532, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538182, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI86565303, Length=201, Percent_Identity=28.8557213930348, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17561272, Length=267, Percent_Identity=23.2209737827715, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17568967, Length=194, Percent_Identity=29.3814432989691, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=269, Percent_Identity=24.1635687732342, Blast_Score=71, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=195, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI23397609, Length=265, Percent_Identity=34.3396226415094, Blast_Score=130, Evalue=8e-31, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=36.5461847389558, Blast_Score=128, Evalue=4e-30, Organism=Drosophila melanogaster, GI21357041, Length=258, Percent_Identity=36.4341085271318, Blast_Score=125, Evalue=4e-29, Organism=Drosophila melanogaster, GI28571526, Length=251, Percent_Identity=35.0597609561753, Blast_Score=123, Evalue=1e-28, Organism=Drosophila melanogaster, GI21355319, Length=244, Percent_Identity=33.6065573770492, Blast_Score=112, Evalue=3e-25, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=30.8, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI24644337, Length=257, Percent_Identity=32.295719844358, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=29.2307692307692, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=32.4742268041237, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=7e-14,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 28926; Mature: 28795
Theoretical pI: Translated: 7.35; Mature: 7.35
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 3.0 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGGQLKGKIAVITGSTQGLGAATARLFAERGAQGLVICGRSAEKGRAQAAGLEELGAKAV CCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCHHHHCCEEE FVQVDLENVEDCRRIVAEADRAFGRLDILVNAAGLTDRGTILDTSPELFDRLFAVNTRAP EEEEECCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCEEECCHHHHHHHHHCCCCCH FFLIQEAIKLFRRDRVEGAIVNVSSMSSMGGQPFIAAYCASKGALDTLTRNVAYSVLRNR HHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHH IRVNSLNIGWMASDGEDRIQREYHGAPANWLEEAVKTQPFGRLLDPAKVARAIAFLASEE HEEEEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCC SGLMTGAIVNFDQSVWGAYDGSPHPEKPL CCCEEEEEEECCHHHCCCCCCCCCCCCCC >Mature Secondary Structure GGQLKGKIAVITGSTQGLGAATARLFAERGAQGLVICGRSAEKGRAQAAGLEELGAKAV CCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHCCHHHHCCEEE FVQVDLENVEDCRRIVAEADRAFGRLDILVNAAGLTDRGTILDTSPELFDRLFAVNTRAP EEEEECCCHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCEEECCHHHHHHHHHCCCCCH FFLIQEAIKLFRRDRVEGAIVNVSSMSSMGGQPFIAAYCASKGALDTLTRNVAYSVLRNR HHHHHHHHHHHHHHCCCCEEEEHHHHHHCCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHH IRVNSLNIGWMASDGEDRIQREYHGAPANWLEEAVKTQPFGRLLDPAKVARAIAFLASEE HEEEEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCC SGLMTGAIVNFDQSVWGAYDGSPHPEKPL CCCEEEEEEECCHHHCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]