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The map label for this gene is cobO [H]

Identifier: 225852796

GI number: 225852796

Start: 1283772

End: 1284410

Strand: Reverse

Name: cobO [H]

Synonym: BMEA_A1352

Alternate gene names: 225852796

Gene position: 1284410-1283772 (Counterclockwise)

Preceding gene: 225852797

Following gene: 225852795

Centisome position: 60.42

GC content: 55.87

Gene sequence:

>639_bases
ATGGCTGAGAAATCGGAAAAACTTCTTTCGATGACCGAGGAGGAGCTGAACGCCCGCCATGCGGACAAGATGCGCAAGAA
GAAAGCCGCCCGCGACAAGATACAGGCGACAAAGACCGAGGAAAAAGGTCTGGTGATCGTCCATACCGGCAAGGGCAAGG
GCAAATCGACGGCCGGTTTCGGCATGGTTTTCCGTGCGCTGGGCCATGGGATGAAGATTGGCGTTGTGCAGTTCGTCAAA
GGGTCGTGGGATACGGGCGAACGCTGGGTTCTGGAGAAGTTTCCCGAGCAGGTGACGATTTCCGCACTGGGCGAAGGCTT
TACCTGGGAAACGCAGGATCGCGCGCGCGATATCGCCATGGCGCGCGGCGCCTGGGAACAGGCCAAGGCGATGATTATGG
ATGAAAGTTACGATATGGTGCTCTGTGACGAGCTTAATATCGTGCTTCGCTACGACTATCTGCCCGTCGAAGAGGTGACC
GAGGTGCTGAAAGCCAAGCCGGAAATGAAGCATGTCATCATCACGGGCCGTAATGCCAAGGACGAGTTGATCGAGGCGGC
GGACCTCGTGACCGAAATGGAGATGATAAAGCATCCTTTCCGTTCCGGTGTGAAGGCGCAGAAAGGCATTGAGTTTTGA

Upstream 100 bases:

>100_bases
ATTGAGCGGGGTTTCTGGACGCCGCGTTCCAATTCCGCGCGTTTCGAGCTGGAAAATTTAAGTGTGCATCTTCAAAAATT
GAATCCGGAAAGGGCGATAA

Downstream 100 bases:

>100_bases
TGATGGCTAGCTGGCAATTCTGGGCATTGATGTCGGCGGTTTTTGCCGCGCTGACGGCGATCTTCGCCAAGGTGGGCATT
CAGGGCATCAATTCGGATTT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MAEKSEKLLSMTEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGFGMVFRALGHGMKIGVVQFVK
GSWDTGERWVLEKFPEQVTISALGEGFTWETQDRARDIAMARGAWEQAKAMIMDESYDMVLCDELNIVLRYDYLPVEEVT
EVLKAKPEMKHVIITGRNAKDELIEAADLVTEMEMIKHPFRSGVKAQKGIEF

Sequences:

>Translated_212_residues
MAEKSEKLLSMTEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGFGMVFRALGHGMKIGVVQFVK
GSWDTGERWVLEKFPEQVTISALGEGFTWETQDRARDIAMARGAWEQAKAMIMDESYDMVLCDELNIVLRYDYLPVEEVT
EVLKAKPEMKHVIITGRNAKDELIEAADLVTEMEMIKHPFRSGVKAQKGIEF
>Mature_211_residues
AEKSEKLLSMTEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGFGMVFRALGHGMKIGVVQFVKG
SWDTGERWVLEKFPEQVTISALGEGFTWETQDRARDIAMARGAWEQAKAMIMDESYDMVLCDELNIVLRYDYLPVEEVTE
VLKAKPEMKHVIITGRNAKDELIEAADLVTEMEMIKHPFRSGVKAQKGIEF

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=194, Percent_Identity=47.9381443298969, Blast_Score=194, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 23919; Mature: 23788

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKSEKLLSMTEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
GMVFRALGHGMKIGVVQFVKGSWDTGERWVLEKFPEQVTISALGEGFTWETQDRARDIAM
HHHHHHHCCCCEEHHHHHCCCCCCCCCHHHHHHCCHHEEHHHHCCCCCCCCHHHHHHHHH
ARGAWEQAKAMIMDESYDMVLCDELNIVLRYDYLPVEEVTEVLKAKPEMKHVIITGRNAK
HHCCHHHHHHHHCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCH
DELIEAADLVTEMEMIKHPFRSGVKAQKGIEF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AEKSEKLLSMTEEELNARHADKMRKKKAARDKIQATKTEEKGLVIVHTGKGKGKSTAGF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
GMVFRALGHGMKIGVVQFVKGSWDTGERWVLEKFPEQVTISALGEGFTWETQDRARDIAM
HHHHHHHCCCCEEHHHHHCCCCCCCCCHHHHHHCCHHEEHHHHCCCCCCCCHHHHHHHHH
ARGAWEQAKAMIMDESYDMVLCDELNIVLRYDYLPVEEVTEVLKAKPEMKHVIITGRNAK
HHCCHHHHHHHHCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCH
DELIEAADLVTEMEMIKHPFRSGVKAQKGIEF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]