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The map label for this gene is cobK [H]

Identifier: 225852790

GI number: 225852790

Start: 1280015

End: 1280761

Strand: Direct

Name: cobK [H]

Synonym: BMEA_A1346

Alternate gene names: 225852790

Gene position: 1280015-1280761 (Clockwise)

Preceding gene: 225852789

Following gene: 225852794

Centisome position: 60.22

GC content: 61.31

Gene sequence:

>747_bases
TTGCCCGCGTCTGAGCCAAAAATCCTCATCCTTGGCGGAACGGCGGAAGCAGCAAGCCTTGCCAGCGCCTTCACCGCCCT
GCCGGTCGCGGCCATCACCTCGCTTGCGGGACGCACCGCTGCTCCTGCAAAACTGAGCGGCCCGGTTCGCAGCGGCGGCT
TTGGCGGAGCGGATGGCCTTGCCGCCTATATCGAGGCCGAGGGAATAGGCCTCGTGATTGACGCGACACATCCCTATGCC
GCGCGCATTTCGCAAAATGCCGTCATTGCCACGGAAGCAACGAAAATCCCTCTTGTCCGGCTGGAGCGCCCGCTTTGGGA
GAAGCAGCCCGGCGACAACTGGATCGATATTGCAAACGAAACAGAAGCCGCGCGCGCCATTCCCCCCGGCGAAAATGTCT
TTCTGGCGCTTGGCCGCCAGCACATTGCGCCTTTTGCAAAGCGCGCCGATGTTCATTTCGTCATCCGCATGATCGACCCA
CCGGAAGTGACCCTTCCCCGGCATTGCGAAATCATTCTGGCAAGGCCCGGCGATTACGATGCGGAAGCAGACTTTCTGAC
AGGGCGCAGGATCGGCCTGATTGTCAGCCGCAATTCGGGCGGAACAGTCTCCTATGCCAAAATCGGGGCCGCGCGCGATC
TGGCCCTGCCGGTGATGATGATCGCCCGCCCGCCGGTTGCGGCGAAAACCGTGGTTGCGACAGTGCCACAAGCCATCGCC
TTTGCCCGCTCTGTTTTAAACTTTTGA

Upstream 100 bases:

>100_bases
GGGCCGATCGCGCTTGAAGCAAGGCAAACGGCGCTCAAAACCCTGCGCGGCGCGCCAGTCGAAGTCGAGATTATCGTTAC
GGACCGCAAGGGAAACATTC

Downstream 100 bases:

>100_bases
GCGCGCCGCGTGGCTATGCGCTTCATGATAGAGGGCCGAATCGCGAAAGTTTTTGGGATCGAGCCCACGCCCGACAAAGA
TCATCGCCGTGCGCCTGAGG

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MPASEPKILILGGTAEAASLASAFTALPVAAITSLAGRTAAPAKLSGPVRSGGFGGADGLAAYIEAEGIGLVIDATHPYA
ARISQNAVIATEATKIPLVRLERPLWEKQPGDNWIDIANETEAARAIPPGENVFLALGRQHIAPFAKRADVHFVIRMIDP
PEVTLPRHCEIILARPGDYDAEADFLTGRRIGLIVSRNSGGTVSYAKIGAARDLALPVMMIARPPVAAKTVVATVPQAIA
FARSVLNF

Sequences:

>Translated_248_residues
MPASEPKILILGGTAEAASLASAFTALPVAAITSLAGRTAAPAKLSGPVRSGGFGGADGLAAYIEAEGIGLVIDATHPYA
ARISQNAVIATEATKIPLVRLERPLWEKQPGDNWIDIANETEAARAIPPGENVFLALGRQHIAPFAKRADVHFVIRMIDP
PEVTLPRHCEIILARPGDYDAEADFLTGRRIGLIVSRNSGGTVSYAKIGAARDLALPVMMIARPPVAAKTVVATVPQAIA
FARSVLNF
>Mature_247_residues
PASEPKILILGGTAEAASLASAFTALPVAAITSLAGRTAAPAKLSGPVRSGGFGGADGLAAYIEAEGIGLVIDATHPYAA
RISQNAVIATEATKIPLVRLERPLWEKQPGDNWIDIANETEAARAIPPGENVFLALGRQHIAPFAKRADVHFVIRMIDPP
EVTLPRHCEIILARPGDYDAEADFLTGRRIGLIVSRNSGGTVSYAKIGAARDLALPVMMIARPPVAAKTVVATVPQAIAF
ARSVLNF

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 25968; Mature: 25837

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPASEPKILILGGTAEAASLASAFTALPVAAITSLAGRTAAPAKLSGPVRSGGFGGADGL
CCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCE
AAYIEAEGIGLVIDATHPYAARISQNAVIATEATKIPLVRLERPLWEKQPGDNWIDIANE
EEEEEECCEEEEEECCCCHHHHCCCCEEEEECCCCCCEEEECCCHHCCCCCCCEEEECCC
TEAARAIPPGENVFLALGRQHIAPFAKRADVHFVIRMIDPPEVTLPRHCEIILARPGDYD
CCHHHCCCCCCCEEEEECCHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCC
AEADFLTGRRIGLIVSRNSGGTVSYAKIGAARDLALPVMMIARPPVAAKTVVATVPQAIA
CCCCEECCCEEEEEEECCCCCEEEEEECCCCCHHHHEEEEEECCCCHHHHHHHHHHHHHH
FARSVLNF
HHHHHHCC
>Mature Secondary Structure 
PASEPKILILGGTAEAASLASAFTALPVAAITSLAGRTAAPAKLSGPVRSGGFGGADGL
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCE
AAYIEAEGIGLVIDATHPYAARISQNAVIATEATKIPLVRLERPLWEKQPGDNWIDIANE
EEEEEECCEEEEEECCCCHHHHCCCCEEEEECCCCCCEEEECCCHHCCCCCCCEEEECCC
TEAARAIPPGENVFLALGRQHIAPFAKRADVHFVIRMIDPPEVTLPRHCEIILARPGDYD
CCHHHCCCCCCCEEEEECCHHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCC
AEADFLTGRRIGLIVSRNSGGTVSYAKIGAARDLALPVMMIARPPVAAKTVVATVPQAIA
CCCCEECCCEEEEEEECCCCCEEEEEECCCCCHHHHEEEEEECCCCHHHHHHHHHHHHHH
FARSVLNF
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200543 [H]