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The map label for this gene is map [H]

Identifier: 225852774

GI number: 225852774

Start: 1262971

End: 1263798

Strand: Direct

Name: map [H]

Synonym: BMEA_A1329

Alternate gene names: 225852774

Gene position: 1262971-1263798 (Clockwise)

Preceding gene: 225852773

Following gene: 225852775

Centisome position: 59.41

GC content: 57.37

Gene sequence:

>828_bases
ATGGTAACCTATATCGAAGCGACAAGCGCACCCGTGAAATATACAGGCCAGATCAGGCTCTACGGCCCCGAAGCCTTCGA
GGCGATGCGCAAGGTCTGCAACCTGACGGCACGTTGCCTTGATGCGCTGAACGATATCGTCAAACCCGGCGTGACCACCA
ATGAGATCGACCGTTTCGTATTTGAATTCGGCATGGACCACGATGCGTTTCCGGCAACGCTGAATTATCGCGGCTACACG
AAATCGACCTGCACATCGATCAACCATGTGGTCTGCCACGGCATCCCGAACGACAAGCCTCTGCGCGAAGGCGATATCGT
CAATATCGACGTGACTTATCTGCTTGACGGCTGGCACGGAGATTCCAGCCGCATGTATGCGGTTGGTGAAATCAAGCGCG
CTTCCGAACGTCTGCTGGAAGTGACCTATGAAAGCCTTCTTCGCGGTATCGCCGCCGTCAAGCCGGGTGCGAAGACCGGC
GCCATCGGCGCGGCGATCCAGACCTATGCCGAAAGCGAACGCTGCTCGGTGGTGCGCGATTTCTGCGGTCATGGCGTCGG
CCGGCTTTTCCATGATGCGCCGAATATCCTGCACTACGGCACCCCCAATGAAGGTGTCGAGATCAAGGAAGGCATGATCT
TCACGATCGAGCCGATGATCAATCTGGGCAAACCGCATGTGAAGGTTCTTGCCGATGGCTGGACGGCGGTGACGCGGGAC
CGCTCCTTGACCGCACAATATGAACACACGGTCGGCGTCACCAGGGATGGCTGCGAGATTTTCACGCTTTCTCCGGCCAA
TATCTTTGGCCCGCCTTCCATGCGGTGA

Upstream 100 bases:

>100_bases
CATCCGGGGTTGAGGCTTGGGCCGTTCGGTGCCACATAACGGAAAATGGCATCGACGCCACAGAGCTGGTGCCAATCGAG
GACATGAGACGGATCGAGTG

Downstream 100 bases:

>100_bases
TTGAAAAGCGGCAATCACTTATTGTCTGATCTGTTTTCGCGGGGGTTTAAACAGAATGGCAAAGAAGAAGGATACGCCCG
GAGATGGCGAATTTCCGGGC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MVTYIEATSAPVKYTGQIRLYGPEAFEAMRKVCNLTARCLDALNDIVKPGVTTNEIDRFVFEFGMDHDAFPATLNYRGYT
KSTCTSINHVVCHGIPNDKPLREGDIVNIDVTYLLDGWHGDSSRMYAVGEIKRASERLLEVTYESLLRGIAAVKPGAKTG
AIGAAIQTYAESERCSVVRDFCGHGVGRLFHDAPNILHYGTPNEGVEIKEGMIFTIEPMINLGKPHVKVLADGWTAVTRD
RSLTAQYEHTVGVTRDGCEIFTLSPANIFGPPSMR

Sequences:

>Translated_275_residues
MVTYIEATSAPVKYTGQIRLYGPEAFEAMRKVCNLTARCLDALNDIVKPGVTTNEIDRFVFEFGMDHDAFPATLNYRGYT
KSTCTSINHVVCHGIPNDKPLREGDIVNIDVTYLLDGWHGDSSRMYAVGEIKRASERLLEVTYESLLRGIAAVKPGAKTG
AIGAAIQTYAESERCSVVRDFCGHGVGRLFHDAPNILHYGTPNEGVEIKEGMIFTIEPMINLGKPHVKVLADGWTAVTRD
RSLTAQYEHTVGVTRDGCEIFTLSPANIFGPPSMR
>Mature_275_residues
MVTYIEATSAPVKYTGQIRLYGPEAFEAMRKVCNLTARCLDALNDIVKPGVTTNEIDRFVFEFGMDHDAFPATLNYRGYT
KSTCTSINHVVCHGIPNDKPLREGDIVNIDVTYLLDGWHGDSSRMYAVGEIKRASERLLEVTYESLLRGIAAVKPGAKTG
AIGAAIQTYAESERCSVVRDFCGHGVGRLFHDAPNILHYGTPNEGVEIKEGMIFTIEPMINLGKPHVKVLADGWTAVTRD
RSLTAQYEHTVGVTRDGCEIFTLSPANIFGPPSMR

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=258, Percent_Identity=46.1240310077519, Blast_Score=245, Evalue=4e-65,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=39.5161290322581, Blast_Score=197, Evalue=1e-50,
Organism=Escherichia coli, GI1786364, Length=248, Percent_Identity=52.0161290322581, Blast_Score=259, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71996291, Length=251, Percent_Identity=45.4183266932271, Blast_Score=222, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6323273, Length=261, Percent_Identity=41.7624521072797, Blast_Score=212, Evalue=6e-56,
Organism=Drosophila melanogaster, GI21355531, Length=258, Percent_Identity=42.2480620155039, Blast_Score=217, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24583427, Length=236, Percent_Identity=42.3728813559322, Blast_Score=200, Evalue=9e-52,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 30274; Mature: 30274

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTYIEATSAPVKYTGQIRLYGPEAFEAMRKVCNLTARCLDALNDIVKPGVTTNEIDRFV
CEEEEECCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FEFGMDHDAFPATLNYRGYTKSTCTSINHVVCHGIPNDKPLREGDIVNIDVTYLLDGWHG
HHHCCCCCCCCCEEECCCCCHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECEEC
DSSRMYAVGEIKRASERLLEVTYESLLRGIAAVKPGAKTGAIGAAIQTYAESERCSVVRD
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHH
FCGHGVGRLFHDAPNILHYGTPNEGVEIKEGMIFTIEPMINLGKPHVKVLADGWTAVTRD
HHCCCHHHHHHCCCCEEECCCCCCCCEECCCEEEEEECHHCCCCCCEEEEECCCEEEECC
RSLTAQYEHTVGVTRDGCEIFTLSPANIFGPPSMR
CCCEEEHHHCCCCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MVTYIEATSAPVKYTGQIRLYGPEAFEAMRKVCNLTARCLDALNDIVKPGVTTNEIDRFV
CEEEEECCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FEFGMDHDAFPATLNYRGYTKSTCTSINHVVCHGIPNDKPLREGDIVNIDVTYLLDGWHG
HHHCCCCCCCCCEEECCCCCHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECEEC
DSSRMYAVGEIKRASERLLEVTYESLLRGIAAVKPGAKTGAIGAAIQTYAESERCSVVRD
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCHHHHHHHHH
FCGHGVGRLFHDAPNILHYGTPNEGVEIKEGMIFTIEPMINLGKPHVKVLADGWTAVTRD
HHCCCHHHHHHCCCCEEECCCCCCCCEECCCEEEEEECHHCCCCCCEEEEECCCEEEECC
RSLTAQYEHTVGVTRDGCEIFTLSPANIFGPPSMR
CCCEEEHHHCCCCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]