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The map label for this gene is queF

Identifier: 225852679

GI number: 225852679

Start: 1178061

End: 1178528

Strand: Direct

Name: queF

Synonym: BMEA_A1227

Alternate gene names: 225852679

Gene position: 1178061-1178528 (Clockwise)

Preceding gene: 225852678

Following gene: 225852681

Centisome position: 55.42

GC content: 57.69

Gene sequence:

>468_bases
ATGTCTGAAAATACGATATATTCCGGCCTGAAACAGCTCGGTTCGCACACAGATATTCCCCTGACACCGGAAGAAGCGGT
TCTGGAGCGCGTGGCAAACCCGCAAGAAGGCACGCCCTATTGCGTGCGCTTCACCGCGCCCGAATTCAGCTCTCTCTGCC
CCATGACCGGTCAGCCGGATTTTGCCCATCTGGTGATCGACTATGTGCCGGGCAAATGGCTGGTTGAGAGCAAATCGCTG
AAGCTCTTCCTCTTTTCCTTCCGCAACCACGGCGCATTTCACGAGGATTGCACCGTAACCATCGGCAAACGCCTTGTGGA
CCTGCTGGAGCCGGAATGGCTGCGGATCGGAGGCTATTGGTATCCGCGCGGCGGCATTCCCATCGATGTTTTCTATCAGA
CCGGGGCAGCCCCCTTGAATGTCTGGATACCCGAACAGGGCGTGGCCAACTATCGGGGCCGTGGCTAG

Upstream 100 bases:

>100_bases
GCAATCCGCCACCGGTCGCAGCCTACCCGGTCAAAACAAGGATACGCGCTTGAAAAAGTGCTGAACGGCTGCCCCGTGGC
TTTTAAAGAAAGACACGCAA

Downstream 100 bases:

>100_bases
AGTCTAGCCAAAAGTGTGAAACGGTTTGGCGCGAAAATGCGATAAAACCAATAGTAAGAACGGCTCCGGTTGCCGCCTCA
AGCCGTCGCCCTTATGGTGA

Product: 7-cyano-7-deazaguanine reductase

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine reductase; NADPH-dependent nitrile oxidoreductase; PreQ(0) reductase

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MSENTIYSGLKQLGSHTDIPLTPEEAVLERVANPQEGTPYCVRFTAPEFSSLCPMTGQPDFAHLVIDYVPGKWLVESKSL
KLFLFSFRNHGAFHEDCTVTIGKRLVDLLEPEWLRIGGYWYPRGGIPIDVFYQTGAAPLNVWIPEQGVANYRGRG

Sequences:

>Translated_155_residues
MSENTIYSGLKQLGSHTDIPLTPEEAVLERVANPQEGTPYCVRFTAPEFSSLCPMTGQPDFAHLVIDYVPGKWLVESKSL
KLFLFSFRNHGAFHEDCTVTIGKRLVDLLEPEWLRIGGYWYPRGGIPIDVFYQTGAAPLNVWIPEQGVANYRGRG
>Mature_154_residues
SENTIYSGLKQLGSHTDIPLTPEEAVLERVANPQEGTPYCVRFTAPEFSSLCPMTGQPDFAHLVIDYVPGKWLVESKSLK
LFLFSFRNHGAFHEDCTVTIGKRLVDLLEPEWLRIGGYWYPRGGIPIDVFYQTGAAPLNVWIPEQGVANYRGRG

Specific function: Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)

COG id: COG0780

COG function: function code R; Enzyme related to GTP cyclohydrolase I

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEF_BRUA1 (B2S630)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935101.1
- ProteinModelPortal:   B2S630
- SMR:   B2S630
- GeneID:   6328670
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I11220
- HOGENOM:   HBG294103
- OMA:   HEDCTVA
- ProtClustDB:   PRK13258
- GO:   GO:0005737
- HAMAP:   MF_00818
- InterPro:   IPR016856
- InterPro:   IPR020602
- PIRSF:   PIRSF027377
- TIGRFAMs:   TIGR03139

Pfam domain/function: PF01227 GTP_cyclohydroI

EC number: =1.7.1.13

Molecular weight: Translated: 17402; Mature: 17271

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENTIYSGLKQLGSHTDIPLTPEEAVLERVANPQEGTPYCVRFTAPEFSSLCPMTGQPD
CCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCHHCCCCCCCCC
FAHLVIDYVPGKWLVESKSLKLFLFSFRNHGAFHEDCTVTIGKRLVDLLEPEWLRIGGYW
CEEEEEEECCCCEEEECCCEEEEEEEECCCCCCCCCCEEHHHHHHHHHCCCCEEEECCEE
YPRGGIPIDVFYQTGAAPLNVWIPEQGVANYRGRG
ECCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SENTIYSGLKQLGSHTDIPLTPEEAVLERVANPQEGTPYCVRFTAPEFSSLCPMTGQPD
CCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCHHCCCCCCCCC
FAHLVIDYVPGKWLVESKSLKLFLFSFRNHGAFHEDCTVTIGKRLVDLLEPEWLRIGGYW
CEEEEEEECCCCEEEECCCEEEEEEEECCCCCCCCCCEEHHHHHHHHHCCCCEEEECCEE
YPRGGIPIDVFYQTGAAPLNVWIPEQGVANYRGRG
ECCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA