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The map label for this gene is hflX [H]

Identifier: 225852611

GI number: 225852611

Start: 1105595

End: 1107013

Strand: Reverse

Name: hflX [H]

Synonym: BMEA_A1155

Alternate gene names: 225852611

Gene position: 1107013-1105595 (Counterclockwise)

Preceding gene: 225852612

Following gene: 225852610

Centisome position: 52.08

GC content: 59.62

Gene sequence:

>1419_bases
TTGTCCAAACCCAAGGATAAAAAAGCGGCATCCCTCGATGGCAGCAAGGGCTTTGCCCTTTCCGAGCCTGAGCCAACGAG
AGCAGCCGTCATTGTTCCCGTCCTGCCGGACCGTTATAATAGCGGCTCTGCGGGCGAGGATGGCGCAAGATCGCAGTTCC
AGCGTTCCAACGAGGCGCGCCTTGAGGAAGCGATCGGGCTTGCGCGCGCAATTGGTCTTGATATCGAACATGCGGAAATC
GCCATCGTCACCAATCCGCGGCCCGCGACGCTGCTTGGTGCGGGCAAGGCCCAATCCATTGCCGAAGTCGTCAAGGAAAA
GGCGATTGGACTGGTGGTTGTCGATCATGCCCTGACGCCGGTGCAGCAGCGCAATCTTGAAAAGGAATGGAACGCCAAGG
TCATCGACCGAACCGGGCTCATTCTGGAGATTTTCGGTGAACGCGCGCGCACCAAGGAAGGCGCGCTTCAGGTGGAGCTG
GCGCATCTCAACTACCAGAAGGGACGCCTTGTCAGAAGCTGGACCCACCTTGAACGCCAGCGCGGCGGTGGGGGCTTCCT
TGGCGGCCCGGGTGAAACCCAGATCGAAGCTGACCGACGCCTGCTTCAGGAAAAAATCCTGCGCATCAAGCGCGAGCTTG
AAACCGTGGTGCGCACGCGCGCGCTGCATCGCCAGAAGCGGCGCAAGGTGCCGCATCCAATTGTTGCGCTTGTCGGCTAT
ACCAATGCGGGAAAATCCACGCTTTTCAACCGCATGACGGGTGCGCAGGTGCTTGCGGAAGATATGCTTTTCGCCACGCT
CGATCCGACCTTGCGCCGCATCCGGCTTCCCCATGGCGAAACGGTCATCCTGTCGGACACGGTGGGCTTTATTTCCAATC
TGCCGCACCATCTCGTTGCCGCTTTCCGGGCAACGCTCGAAGAAGTGGTGGAGGCCGACCTGATCCTGCATGTCCGTGAT
ATTTCCGACCCCGACAACGCGGCGCAGGCCGAGGATGTGGAGAATATTCTGGCTGGTCTCGGTATCGAGCCGCAGGACCA
TGCCCGCGTCGTGGAGGTCTGGAACAAGATCGACAATCTCGACGAAAGTGCGCGTGAGGCAGCCTTGCGCCTTGCCGCCG
CCGGAAGCGAGGAGGGGCGCCCGATCCCTGTTTCGGCTATCACCGGTGAAGGCGTTGACAGGTTGCTTTCGCTTATCGAA
ACACGGATAGCAGGTGCGCTTGGATCGGTCGATCTGGTGCTTTCGCCTTTCGATCTGCATCTTCTCGACTGGATTTACCA
GCACGGCAGCGATGTTCAGCGTGAAAACCTTGAAGACGGTTCGGTTCGTATCAAGGCGCGGCTGACCGAAATCGCCCGCA
GGATGCTGGACGAAAAGCGCGGCATCCGGCCTGAAAAGCCTGAGATCGATTGGGAGTAG

Upstream 100 bases:

>100_bases
ATTGCTTGAACGTTCCGGGGCGTCTTCATTTGAAACAGCTTACGCGGTGATTTATCTGCAAGGCAGATCCATGCGTTCCC
GCGTCCCCGGAGAATATTAC

Downstream 100 bases:

>100_bases
GCGGATATTTCGCGCCACTTGCGGAACAGGGGCGCAACGCCCTATGTATGGAAGTCCGACGATTCAACCTAGTCATATCG
CCATTAATATATCAGAGGCC

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSKPKDKKAASLDGSKGFALSEPEPTRAAVIVPVLPDRYNSGSAGEDGARSQFQRSNEARLEEAIGLARAIGLDIEHAEI
AIVTNPRPATLLGAGKAQSIAEVVKEKAIGLVVVDHALTPVQQRNLEKEWNAKVIDRTGLILEIFGERARTKEGALQVEL
AHLNYQKGRLVRSWTHLERQRGGGGFLGGPGETQIEADRRLLQEKILRIKRELETVVRTRALHRQKRRKVPHPIVALVGY
TNAGKSTLFNRMTGAQVLAEDMLFATLDPTLRRIRLPHGETVILSDTVGFISNLPHHLVAAFRATLEEVVEADLILHVRD
ISDPDNAAQAEDVENILAGLGIEPQDHARVVEVWNKIDNLDESAREAALRLAAAGSEEGRPIPVSAITGEGVDRLLSLIE
TRIAGALGSVDLVLSPFDLHLLDWIYQHGSDVQRENLEDGSVRIKARLTEIARRMLDEKRGIRPEKPEIDWE

Sequences:

>Translated_472_residues
MSKPKDKKAASLDGSKGFALSEPEPTRAAVIVPVLPDRYNSGSAGEDGARSQFQRSNEARLEEAIGLARAIGLDIEHAEI
AIVTNPRPATLLGAGKAQSIAEVVKEKAIGLVVVDHALTPVQQRNLEKEWNAKVIDRTGLILEIFGERARTKEGALQVEL
AHLNYQKGRLVRSWTHLERQRGGGGFLGGPGETQIEADRRLLQEKILRIKRELETVVRTRALHRQKRRKVPHPIVALVGY
TNAGKSTLFNRMTGAQVLAEDMLFATLDPTLRRIRLPHGETVILSDTVGFISNLPHHLVAAFRATLEEVVEADLILHVRD
ISDPDNAAQAEDVENILAGLGIEPQDHARVVEVWNKIDNLDESAREAALRLAAAGSEEGRPIPVSAITGEGVDRLLSLIE
TRIAGALGSVDLVLSPFDLHLLDWIYQHGSDVQRENLEDGSVRIKARLTEIARRMLDEKRGIRPEKPEIDWE
>Mature_471_residues
SKPKDKKAASLDGSKGFALSEPEPTRAAVIVPVLPDRYNSGSAGEDGARSQFQRSNEARLEEAIGLARAIGLDIEHAEIA
IVTNPRPATLLGAGKAQSIAEVVKEKAIGLVVVDHALTPVQQRNLEKEWNAKVIDRTGLILEIFGERARTKEGALQVELA
HLNYQKGRLVRSWTHLERQRGGGGFLGGPGETQIEADRRLLQEKILRIKRELETVVRTRALHRQKRRKVPHPIVALVGYT
NAGKSTLFNRMTGAQVLAEDMLFATLDPTLRRIRLPHGETVILSDTVGFISNLPHHLVAAFRATLEEVVEADLILHVRDI
SDPDNAAQAEDVENILAGLGIEPQDHARVVEVWNKIDNLDESAREAALRLAAAGSEEGRPIPVSAITGEGVDRLLSLIET
RIAGALGSVDLVLSPFDLHLLDWIYQHGSDVQRENLEDGSVRIKARLTEIARRMLDEKRGIRPEKPEIDWE

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=302, Percent_Identity=34.7682119205298, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI310133116, Length=287, Percent_Identity=35.191637630662, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI310124269, Length=271, Percent_Identity=35.7933579335793, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI310124267, Length=271, Percent_Identity=35.7933579335793, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI310124171, Length=271, Percent_Identity=35.7933579335793, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI310124169, Length=271, Percent_Identity=35.7933579335793, Blast_Score=145, Evalue=1e-34,
Organism=Escherichia coli, GI1790615, Length=439, Percent_Identity=44.1913439635535, Blast_Score=296, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17561038, Length=344, Percent_Identity=33.7209302325581, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24650079, Length=408, Percent_Identity=32.1078431372549, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 52023; Mature: 51892

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPKDKKAASLDGSKGFALSEPEPTRAAVIVPVLPDRYNSGSAGEDGARSQFQRSNEAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCHHHH
LEEAIGLARAIGLDIEHAEIAIVTNPRPATLLGAGKAQSIAEVVKEKAIGLVVVDHALTP
HHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCEEEECCCCCC
VQQRNLEKEWNAKVIDRTGLILEIFGERARTKEGALQVELAHLNYQKGRLVRSWTHLERQ
HHHHCCCHHCCCEEECCCCHHHEECCCHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
RGGGGFLGGPGETQIEADRRLLQEKILRIKRELETVVRTRALHRQKRRKVPHPIVALVGY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
TNAGKSTLFNRMTGAQVLAEDMLFATLDPTLRRIRLPHGETVILSDTVGFISNLPHHLVA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEEEECCHHHHHCCHHHHHH
AFRATLEEVVEADLILHVRDISDPDNAAQAEDVENILAGLGIEPQDHARVVEVWNKIDNL
HHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
DESAREAALRLAAAGSEEGRPIPVSAITGEGVDRLLSLIETRIAGALGSVDLVLSPFDLH
CHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHH
LLDWIYQHGSDVQRENLEDGSVRIKARLTEIARRMLDEKRGIRPEKPEIDWE
HHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SKPKDKKAASLDGSKGFALSEPEPTRAAVIVPVLPDRYNSGSAGEDGARSQFQRSNEAR
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHCCHHHH
LEEAIGLARAIGLDIEHAEIAIVTNPRPATLLGAGKAQSIAEVVKEKAIGLVVVDHALTP
HHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCEEEECCCCCC
VQQRNLEKEWNAKVIDRTGLILEIFGERARTKEGALQVELAHLNYQKGRLVRSWTHLERQ
HHHHCCCHHCCCEEECCCCHHHEECCCHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
RGGGGFLGGPGETQIEADRRLLQEKILRIKRELETVVRTRALHRQKRRKVPHPIVALVGY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
TNAGKSTLFNRMTGAQVLAEDMLFATLDPTLRRIRLPHGETVILSDTVGFISNLPHHLVA
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEEEECCHHHHHCCHHHHHH
AFRATLEEVVEADLILHVRDISDPDNAAQAEDVENILAGLGIEPQDHARVVEVWNKIDNL
HHHHHHHHHHHHHHEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
DESAREAALRLAAAGSEEGRPIPVSAITGEGVDRLLSLIETRIAGALGSVDLVLSPFDLH
CHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHH
LLDWIYQHGSDVQRENLEDGSVRIKARLTEIARRMLDEKRGIRPEKPEIDWE
HHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]