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The map label for this gene is clpX

Identifier: 225852609

GI number: 225852609

Start: 1103205

End: 1104479

Strand: Reverse

Name: clpX

Synonym: BMEA_A1153

Alternate gene names: 225852609

Gene position: 1104479-1103205 (Counterclockwise)

Preceding gene: 225852610

Following gene: 225852608

Centisome position: 51.96

GC content: 56.31

Gene sequence:

>1275_bases
ATGAGCAAAGTCAGCAACGGCGGCGGCGATTCCAAGAATACGCTTTATTGCTCGTTCTGTGGCAAAAGCCAGCATGAAGT
GCGCAAGCTGATTGCAGGCCCGACCGTTTTCATCTGCGACGAATGCGTCGAACTCTGCATGGACATCATCCGTGAGGAAA
ACAAATCCTCCATGGTGAAGTCGCGTGAGGGAGTGCCGACGCCGCAGGAAATCATGGCCGTCCTTGACGATTACGTCATC
GGCCAGAAGGATGCCAAGCGCGTTCTGTCGGTTGCGGTTCACAATCATTACAAGCGTCTGGCGCATCAGTCCAAGAACAG
CGATATCGAACTGGCGAAGTCGAACATTCTGCTCGTCGGCCCGACGGGCTGCGGCAAGACCTATCTTGCCCAGACGCTTG
CCCGCATCATCGATGTGCCGTTCATCATGGCGGATGCGACGACGCTGACGGAAGCCGGCTATGTCGGCGAAGATGTGGAG
AACATCATCCTGAAGCTGCTTCAGGCCGCCGATTATAATGTGGAGCGCGCGCAGCGCGGCATCGTCTATATTGATGAAGT
GGACAAGATCAGCCGCAAGTCGGACAATCCATCCATTACCCGTGACGTATCGGGCGAGGGTGTGCAGCAGGCCCTGCTGA
AGATCATGGAAGGCACTGTCGCTTCCGTGCCGCCGCAGGGTGGGCGCAAGCATCCGCAGCAGGAATTCTTGCAGGTGGAT
ACGACAAACATCCTGTTTATCTGCGGTGGTGCTTTTGCGGGTCTCGACCGTATCATTTCCGCTCGCGGCGAGAAGACCTC
CATCGGCTTTGGCGCTACGGTCAAGTCCGTCGATGAGCGTCGTATCGGTGAAGTCTTCAAGGAATTGGAACCGGAAGACC
TGTTGAAATTCGGCCTGATTCCGGAATTTGTCGGTCGTCTGCCTGTCATCGCTACGCTCGAAGACCTCGACGTCGATGCT
CTGGTCCAGATTCTGACCGAGCCGAAGAATGCGCTCGTGAAGCAGTATCAGCGCCTGTTCGACATGGAAAATGTCGAACT
GGTGTTCCATGACGATGCGTTGCGCGCGATTGCCAACAAGGCTGTCGAACGCAAGACGGGTGCACGCGGCCTGCGTTCGA
TCATGGAAAAGATTCTGCTCGATACCATGTTTGAACTGCCGACGCTGGAAGGCGTTCGCGAAGTTGTGATTTCGGGCGAT
GTGGTGGATGGAAGCGCCCGCCCGCTATACATCTACGCCGAGCGGCAGGACGAAAAGGGCAACGTTTCAGCCTGA

Upstream 100 bases:

>100_bases
GGCGGGAGGCGCGTTTTCCCTCCCGGACCGGGTCCGAACCGGAAGAAACGATTGATCTGGACGCCCAAGGTCCATTTCGG
TCAATTGAAAGGAAACTGCG

Downstream 100 bases:

>100_bases
ATGGCATGAAATGTCCCTGAAAAGGCCGCGAAAGCGGCCTTTTTCATGTGCTAACCTTGCGTCAGCTTTTGCTCCCGCCA
GGGCGGCGGCAACAGGGGCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVI
GQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVE
NIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
TTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDA
LVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVERKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGD
VVDGSARPLYIYAERQDEKGNVSA

Sequences:

>Translated_424_residues
MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVI
GQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVE
NIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
TTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDA
LVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVERKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGD
VVDGSARPLYIYAERQDEKGNVSA
>Mature_423_residues
SKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVIG
QKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVEN
IILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDT
TNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDAL
VQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVERKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDV
VDGSARPLYIYAERQDEKGNVSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=336, Percent_Identity=53.8690476190476, Blast_Score=330, Evalue=2e-90,
Organism=Escherichia coli, GI1786642, Length=414, Percent_Identity=69.8067632850241, Blast_Score=589, Evalue=1e-169,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=44.3396226415094, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=296, Percent_Identity=48.9864864864865, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71982905, Length=321, Percent_Identity=47.3520249221184, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=39.4871794871795, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI71988660, Length=258, Percent_Identity=38.7596899224806, Blast_Score=168, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=417, Percent_Identity=37.6498800959233, Blast_Score=258, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24648291, Length=323, Percent_Identity=51.3931888544892, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI24648289, Length=323, Percent_Identity=51.3931888544892, Blast_Score=319, Evalue=3e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_BRUO2 (A5VQN3)

Other databases:

- EMBL:   CP000708
- RefSeq:   YP_001259030.1
- ProteinModelPortal:   A5VQN3
- GeneID:   5202837
- GenomeReviews:   CP000708_GR
- KEGG:   bov:BOV_1066
- TIGR:   BOV_1066
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- ProtClustDB:   PRK05342
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46656; Mature: 46525

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVK
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
SREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVG
HCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEC
PTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRG
CCCCCHHHHHHHHHHHHCCCHHEECCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCC
IVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
CEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHC
TTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLI
CCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCC
PEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANK
HHHHCCCCEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHH
AVERKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCCEEEEEEECCCCCC
NVSA
CCCC
>Mature Secondary Structure 
SKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVK
CCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHH
SREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVG
HCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEC
PTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRG
CCCCCHHHHHHHHHHHHCCCHHEECCHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHCC
IVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVD
CEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHHHC
TTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLI
CCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCC
PEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANK
HHHHCCCCEEEEHHHCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHH
AVERKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEECCCCCEEEEEEECCCCCC
NVSA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA