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The map label for this gene is arsC [H]

Identifier: 225852494

GI number: 225852494

Start: 971822

End: 972169

Strand: Direct

Name: arsC [H]

Synonym: BMEA_A1029

Alternate gene names: 225852494

Gene position: 971822-972169 (Clockwise)

Preceding gene: 225852493

Following gene: 225852495

Centisome position: 45.72

GC content: 55.46

Gene sequence:

>348_bases
ATGGATGTAACCATCTATCACAATCCTGTATGCGGCACGTCGCGCAAGGTACTTGGAATGATCCGGGAAGCCGGAATCGA
GCCGCATGTCATCGAATATATGAAAACGCCGCTTCCAAGGGACATGCTGGTGGAATTGCTGCGGCAGATGGCTATTTCGC
CGCGCGCCCTGCTGCGGGCAAAAGAAGCGCGCTATGCGGAACTGGGGCTCGATGATCCTGCACTTTCTGATGAGGTTCTG
ATTGACGCCATGATAAGCAACCCCGTGCTGATGAACCGGCCCGTGGTCGTTACGCCCAAAGGTGTTCGTCTTTGCCGCCC
GGCAGAAACGGTTCAGGAGTTGCTATAG

Upstream 100 bases:

>100_bases
TGATAATGGAAACAGGCTTCTGTGCATATCTTTCAGGCTTTGCGATGTTGCAGCCGCTTTATGATAAAAGACCAATTTCC
GAAAATCAGCGGAGACGACC

Downstream 100 bases:

>100_bases
GCGCGCGGCGCAAATGCATATGGTTTTCCACAGCGCGAAGCAATCAAAAATCAGCATGTCCGATCCTTCACTTCGTCAGG
GAATGCTTTCAAAAAAATGA

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenical pump modifier [H]

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MDVTIYHNPVCGTSRKVLGMIREAGIEPHVIEYMKTPLPRDMLVELLRQMAISPRALLRAKEARYAELGLDDPALSDEVL
IDAMISNPVLMNRPVVVTPKGVRLCRPAETVQELL

Sequences:

>Translated_115_residues
MDVTIYHNPVCGTSRKVLGMIREAGIEPHVIEYMKTPLPRDMLVELLRQMAISPRALLRAKEARYAELGLDDPALSDEVL
IDAMISNPVLMNRPVVVTPKGVRLCRPAETVQELL
>Mature_115_residues
MDVTIYHNPVCGTSRKVLGMIREAGIEPHVIEYMKTPLPRDMLVELLRQMAISPRALLRAKEARYAELGLDDPALSDEVL
IDAMISNPVLMNRPVVVTPKGVRLCRPAETVQELL

Specific function: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance [H]

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family [H]

Homologues:

Organism=Escherichia coli, GI1789918, Length=114, Percent_Identity=56.140350877193, Blast_Score=134, Evalue=2e-33,
Organism=Escherichia coli, GI1788841, Length=114, Percent_Identity=46.4912280701754, Blast_Score=102, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006659
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: =1.20.4.1 [H]

Molecular weight: Translated: 12861; Mature: 12861

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVTIYHNPVCGTSRKVLGMIREAGIEPHVIEYMKTPLPRDMLVELLRQMAISPRALLRA
CCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHH
KEARYAELGLDDPALSDEVLIDAMISNPVLMNRPVVVTPKGVRLCRPAETVQELL
HHHHHHHCCCCCCCCCHHHHHHHHHCCCEECCCCEEECCCCCCEECCHHHHHHHC
>Mature Secondary Structure
MDVTIYHNPVCGTSRKVLGMIREAGIEPHVIEYMKTPLPRDMLVELLRQMAISPRALLRA
CCEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHH
KEARYAELGLDDPALSDEVLIDAMISNPVLMNRPVVVTPKGVRLCRPAETVQELL
HHHHHHHCCCCCCCCCHHHHHHHHHCCCEECCCCEEECCCCCCEECCHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3021763; 1703401; 1704144 [H]