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The map label for this gene is nqo3 [H]

Identifier: 225852324

GI number: 225852324

Start: 805865

End: 807949

Strand: Direct

Name: nqo3 [H]

Synonym: BMEA_A0850

Alternate gene names: 225852324

Gene position: 805865-807949 (Clockwise)

Preceding gene: 225852323

Following gene: 225852325

Centisome position: 37.91

GC content: 61.1

Gene sequence:

>2085_bases
ATGGCAAAGATCAAGGTTGACGGCACAGAGATCGAAGTACCCGATCACTATACGCTCCTTCAGGCTGCCGAAGCGGCGGG
CGCGGAAGTGCCACGTTTCTGTTTCCACGAACGGCTTTCCATCGCCGGAAACTGCCGTATGTGCCTGGTTGAAGTGAAGG
GCGGCCCGCCGAAGCCGGCGGCATCCTGCGCCATGGGCGTGCGCGATCTGCGTCCCGGCCCGAATGGCGAAGCACCTGAA
ATCTTCACCAATACGCCGATGGTCAAGAAGGCCCGCGAAGGCGTGATGGAATTCCTGCTCATCAACCACCCGCTGGATTG
CCCGATCTGCGATCAGGGCGGCGAGTGCGACTTGCAGGATCAGGCAATGGCTTTCGGCACGGATGGCTCGCGCTTCCGTG
AAAACAAGCGTGCTGTTGAAAACAAATATATCGGCCCGCTCGTCAAGACGGTGATGACGCGCTGCATTCACTGCACGCGC
TGCGTCCGCTTCACGACGGAAGTGGCGGGCATTTCGGAACTGGGCCTCATCGGCCGCGGCGAAGACGCCGAAATCACCAC
CTATCTCGAACGCGCCATGACGTCGGAATTGCAGGGCAACGTCATTGATCTTTGCCCGGTTGGGGCTCTGACCTCGCGTC
CTTATGCTTTCCAGGCGCGTCCGTGGGAACTGAACAAGACCGAAACCATCGACGTGATGGATGCGGTCGGTTCCAACATC
CGCGTTGACACCCGTGGCCGTGAAGTGATGCGCATCATGCCGCGCGTCAACGAACAGGTGAACGAGGAGTGGATTTCGGA
CAAGACCCGTTTCATCTGGGATGGCCTGCGCACCCAGCGCCTCGACCGTCCTTATGTCCGCAAGGATGGCCGTCTGGTTG
CCGCCACCTGGCCGGAAGCCTTTGCTGCCATTGCCGCCAAGGTTTCCGCAACCTCGGCTGAAAAGATCGGCGCTGTTGCA
GGCGATCTGGCTTCGGTTGAAGAAATCTATGCGCTGAAGGGCCTGATGACTGCGCTCGGCACCGCCAATATCGATTGCCG
CCAGGATGGCGCCGCTCTCGATCCGGCACTGGGCCGCGCAACCTATCTTTTCAATTCTACGATTGAAGGTATTGAAAACG
CTGATGCTTTGCTCATAATCGGTTCCAATCCGCGCATCGAGGCCGCAGTCCTGAACGCCCGTATCCGCAAGCGCCAGCGC
ATGGGCCATTTCCCGGTCGCCCTGATCGGCGAACAGGCTGAACTGCGTTACGATTACGAATATCTGGGTAGCAGTGCTGA
AACGCTTGGCCAGCTGGCTTCCGGCAGACACGCCTTCCGTGACGTGCTGGCCAAGGCCGAACGTCCGCTGATTATCATCG
GTCAGGGTGCGCTCACCGGCGAAGACGGCCGTGCGGTTCTGTCAACCGCCGCCAAACTCGCTCAGGACGTCGGCGCGATC
AAGGACGACTGGAACGGCTTCTCCGTTCTGCACACCGCTGCTTCGCGCGTTGGCGCTCTGGACCTCGGCTTTGTGCCGGG
CGAGGGCGGCAAGGCAGCGCGCGACATGCTGGGCAATCTCGATGTCGTGTTCCTGCTCGGTGCAGACGAACTCGACATGA
TGGCCAAGAGTTCGAGCTTCGTCGTTTACATCGGCACGCATGGCGATGCCGGTGCACATGCCGCCGACGTTATCCTGCCG
GGGGCCGCCTATACGGAAAAGTCGGGCACCTGGCTCAACACCGAAGGTCGCGTGCAGCTTGGCAACCGTGCCGGTTTCGC
ACCGGGCGAGGCGAAGGAAGACTGGGCAATCCTGCGCGCTCTTTCCGACAGCCTGGGCAAGCGCCTGCCGTTCGATTCGT
TGCAGCAGCTTCGCGCCAAACTCTATGCGGACTATCCGCATATGCTGGCCATCGACACCATTACGCCTGCTTCCGCCGAC
GATCTTGTCGCGCTGGCGGCGAAAGCATCCAATCCGGGCAACGGCGCTGCGTTCGTTTCCCCGGTCAAGGACTTCTACCT
GACGAACCCAATCGCGCGCGCTTCCGCCGTCATGGCCGAATGCTCGGCGCTCGCGGCCGGCGGCTTCCAACAGGCAGCTG
AGTAA

Upstream 100 bases:

>100_bases
AAAAGTGCCTGGCGGTTTTCGGAAAAGGCCATGCCAATCAAGCGCAGGTACAAAAGTTTGAGATGGAAGATGCGGCATGA
GCCGCAGGTTTGGATAAGCG

Downstream 100 bases:

>100_bases
GCGAGAGAGAGACGGAACAATGGAAGGAATTTTTGCAGCTTACGTCTTGCCCGCGCTTATCATAGCGCTGAAGTCGGTCG
TTCTGCTCGTCGTATTGCTG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 3; NDH-1, chain 3 [H]

Number of amino acids: Translated: 694; Mature: 693

Protein sequence:

>694_residues
MAKIKVDGTEIEVPDHYTLLQAAEAAGAEVPRFCFHERLSIAGNCRMCLVEVKGGPPKPAASCAMGVRDLRPGPNGEAPE
IFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAFGTDGSRFRENKRAVENKYIGPLVKTVMTRCIHCTR
CVRFTTEVAGISELGLIGRGEDAEITTYLERAMTSELQGNVIDLCPVGALTSRPYAFQARPWELNKTETIDVMDAVGSNI
RVDTRGREVMRIMPRVNEQVNEEWISDKTRFIWDGLRTQRLDRPYVRKDGRLVAATWPEAFAAIAAKVSATSAEKIGAVA
GDLASVEEIYALKGLMTALGTANIDCRQDGAALDPALGRATYLFNSTIEGIENADALLIIGSNPRIEAAVLNARIRKRQR
MGHFPVALIGEQAELRYDYEYLGSSAETLGQLASGRHAFRDVLAKAERPLIIIGQGALTGEDGRAVLSTAAKLAQDVGAI
KDDWNGFSVLHTAASRVGALDLGFVPGEGGKAARDMLGNLDVVFLLGADELDMMAKSSSFVVYIGTHGDAGAHAADVILP
GAAYTEKSGTWLNTEGRVQLGNRAGFAPGEAKEDWAILRALSDSLGKRLPFDSLQQLRAKLYADYPHMLAIDTITPASAD
DLVALAAKASNPGNGAAFVSPVKDFYLTNPIARASAVMAECSALAAGGFQQAAE

Sequences:

>Translated_694_residues
MAKIKVDGTEIEVPDHYTLLQAAEAAGAEVPRFCFHERLSIAGNCRMCLVEVKGGPPKPAASCAMGVRDLRPGPNGEAPE
IFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAFGTDGSRFRENKRAVENKYIGPLVKTVMTRCIHCTR
CVRFTTEVAGISELGLIGRGEDAEITTYLERAMTSELQGNVIDLCPVGALTSRPYAFQARPWELNKTETIDVMDAVGSNI
RVDTRGREVMRIMPRVNEQVNEEWISDKTRFIWDGLRTQRLDRPYVRKDGRLVAATWPEAFAAIAAKVSATSAEKIGAVA
GDLASVEEIYALKGLMTALGTANIDCRQDGAALDPALGRATYLFNSTIEGIENADALLIIGSNPRIEAAVLNARIRKRQR
MGHFPVALIGEQAELRYDYEYLGSSAETLGQLASGRHAFRDVLAKAERPLIIIGQGALTGEDGRAVLSTAAKLAQDVGAI
KDDWNGFSVLHTAASRVGALDLGFVPGEGGKAARDMLGNLDVVFLLGADELDMMAKSSSFVVYIGTHGDAGAHAADVILP
GAAYTEKSGTWLNTEGRVQLGNRAGFAPGEAKEDWAILRALSDSLGKRLPFDSLQQLRAKLYADYPHMLAIDTITPASAD
DLVALAAKASNPGNGAAFVSPVKDFYLTNPIARASAVMAECSALAAGGFQQAAE
>Mature_693_residues
AKIKVDGTEIEVPDHYTLLQAAEAAGAEVPRFCFHERLSIAGNCRMCLVEVKGGPPKPAASCAMGVRDLRPGPNGEAPEI
FTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAMAFGTDGSRFRENKRAVENKYIGPLVKTVMTRCIHCTRC
VRFTTEVAGISELGLIGRGEDAEITTYLERAMTSELQGNVIDLCPVGALTSRPYAFQARPWELNKTETIDVMDAVGSNIR
VDTRGREVMRIMPRVNEQVNEEWISDKTRFIWDGLRTQRLDRPYVRKDGRLVAATWPEAFAAIAAKVSATSAEKIGAVAG
DLASVEEIYALKGLMTALGTANIDCRQDGAALDPALGRATYLFNSTIEGIENADALLIIGSNPRIEAAVLNARIRKRQRM
GHFPVALIGEQAELRYDYEYLGSSAETLGQLASGRHAFRDVLAKAERPLIIIGQGALTGEDGRAVLSTAAKLAQDVGAIK
DDWNGFSVLHTAASRVGALDLGFVPGEGGKAARDMLGNLDVVFLLGADELDMMAKSSSFVVYIGTHGDAGAHAADVILPG
AAYTEKSGTWLNTEGRVQLGNRAGFAPGEAKEDWAILRALSDSLGKRLPFDSLQQLRAKLYADYPHMLAIDTITPASADD
LVALAAKASNPGNGAAFVSPVKDFYLTNPIARASAVMAECSALAAGGFQQAAE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=710, Percent_Identity=49.2957746478873, Blast_Score=671, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=705, Percent_Identity=26.8085106382979, Blast_Score=193, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17565758, Length=696, Percent_Identity=48.7068965517241, Blast_Score=628, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI32566231, Length=609, Percent_Identity=50.2463054187192, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI193209088, Length=256, Percent_Identity=60.15625, Blast_Score=322, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24640559, Length=687, Percent_Identity=49.9272197962154, Blast_Score=641, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640557, Length=687, Percent_Identity=49.9272197962154, Blast_Score=641, Evalue=0.0,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 74517; Mature: 74385

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIKVDGTEIEVPDHYTLLQAAEAAGAEVPRFCFHERLSIAGNCRMCLVEVKGGPPKPA
CCEEEECCCEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCH
ASCAMGVRDLRPGPNGEAPEIFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQD
HHHHHCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QAMAFGTDGSRFRENKRAVENKYIGPLVKTVMTRCIHCTRCVRFTTEVAGISELGLIGRG
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
EDAEITTYLERAMTSELQGNVIDLCPVGALTSRPYAFQARPWELNKTETIDVMDAVGSNI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCCCCCCCCEEHHHHHCCCCE
RVDTRGREVMRIMPRVNEQVNEEWISDKTRFIWDGLRTQRLDRPYVRKDGRLVAATWPEA
EEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHCCCCCCCCCCEEEEEECHHH
FAAIAAKVSATSAEKIGAVAGDLASVEEIYALKGLMTALGTANIDCRQDGAALDPALGRA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCC
TYLFNSTIEGIENADALLIIGSNPRIEAAVLNARIRKRQRMGHFPVALIGEQAELRYDYE
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHEEECHH
YLGSSAETLGQLASGRHAFRDVLAKAERPLIIIGQGALTGEDGRAVLSTAAKLAQDVGAI
HHCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCEECCCCHHHHHHHHHHHHHHCCH
KDDWNGFSVLHTAASRVGALDLGFVPGEGGKAARDMLGNLDVVFLLGADELDMMAKSSSF
HCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCHHHHHHCCCCE
VVYIGTHGDAGAHAADVILPGAAYTEKSGTWLNTEGRVQLGNRAGFAPGEAKEDWAILRA
EEEEECCCCCCCCEEHEEECCCCEECCCCCEECCCCCEEECCCCCCCCCCCCHHHHHHHH
LSDSLGKRLPFDSLQQLRAKLYADYPHMLAIDTITPASADDLVALAAKASNPGNGAAFVS
HHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCEEHH
PVKDFYLTNPIARASAVMAECSALAAGGFQQAAE
HHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure 
AKIKVDGTEIEVPDHYTLLQAAEAAGAEVPRFCFHERLSIAGNCRMCLVEVKGGPPKPA
CEEEECCCEEECCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCCCCH
ASCAMGVRDLRPGPNGEAPEIFTNTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQD
HHHHHCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
QAMAFGTDGSRFRENKRAVENKYIGPLVKTVMTRCIHCTRCVRFTTEVAGISELGLIGRG
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
EDAEITTYLERAMTSELQGNVIDLCPVGALTSRPYAFQARPWELNKTETIDVMDAVGSNI
CCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCCCCCCCCEEHHHHHCCCCE
RVDTRGREVMRIMPRVNEQVNEEWISDKTRFIWDGLRTQRLDRPYVRKDGRLVAATWPEA
EEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHHHHCCCCCCCCCCEEEEEECHHH
FAAIAAKVSATSAEKIGAVAGDLASVEEIYALKGLMTALGTANIDCRQDGAALDPALGRA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCC
TYLFNSTIEGIENADALLIIGSNPRIEAAVLNARIRKRQRMGHFPVALIGEQAELRYDYE
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCHHEEECHH
YLGSSAETLGQLASGRHAFRDVLAKAERPLIIIGQGALTGEDGRAVLSTAAKLAQDVGAI
HHCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCEECCCCHHHHHHHHHHHHHHCCH
KDDWNGFSVLHTAASRVGALDLGFVPGEGGKAARDMLGNLDVVFLLGADELDMMAKSSSF
HCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCEEEEECCCHHHHHHCCCCE
VVYIGTHGDAGAHAADVILPGAAYTEKSGTWLNTEGRVQLGNRAGFAPGEAKEDWAILRA
EEEEECCCCCCCCEEHEEECCCCEECCCCCEECCCCCEEECCCCCCCCCCCCHHHHHHHH
LSDSLGKRLPFDSLQQLRAKLYADYPHMLAIDTITPASADDLVALAAKASNPGNGAAFVS
HHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCEEHH
PVKDFYLTNPIARASAVMAECSALAAGGFQQAAE
HHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1605643; 8422400 [H]