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The map label for this gene is nuoE [H]

Identifier: 225852322

GI number: 225852322

Start: 803706

End: 804419

Strand: Direct

Name: nuoE [H]

Synonym: BMEA_A0848

Alternate gene names: 225852322

Gene position: 803706-804419 (Clockwise)

Preceding gene: 225852321

Following gene: 225852323

Centisome position: 37.81

GC content: 58.54

Gene sequence:

>714_bases
ATGTCCGTTCGCCGTCTCGCAGATGATGCCGTCCAGCCAGCCACTTTCGCGTTTAACGCGGAAAATGAGGCTTGGGCACA
CAAGACGATCGCAAAATATCCGGAAGGCCGTCAGCAGTCGGCTGTCATTCCGCTGCTCATGCGTGCGCAGGAACAGGAAG
GCTGGGTTACGAAAGCGTCGATCGAATATGTCGCCGCCATGCTCAACATGCCGCTGATCCGCGTTCTGGAAGTGGCAACC
TTCTATACGCAGTTCCAGTTGAAGCCGGTTGGCTCGCGCGCTCACATTCAGGTTTGCGGCACCACGCCCTGCATGTTGCG
CGGTTCAGAGGCTTTGATGGATGTTTGCCGTCACAAAATCCACCATGACCCGTTCGAGCTGAATGCCGACGGCACGCTGT
CGTGGGAAGAGGTGGAATGTCAGGGCGCTTGCGCCAACGCGCCGATGGTCATGATCTTCAAGGACGCCTATGAAGACCTG
ACGCCGGAACGCCTGGCTGAAATCATCGATGCTTTTGAGGCAGGCAAGGGCGACACGATCAAGCCCGGCCCGCAGGATGG
CCGTGTGACGTCGGAACCGGCCAGCGGCCTGACCGCGCTTACCAAGGATCTGGACTACAAGAAGATCGGCCTCGAAACCC
GCAAGGCGTCGGATGCAGCAGCAGCTAAAGCTAAGGCCGAAGCCGAGGCAGCAACAAAAGACGGAAACAGGTGA

Upstream 100 bases:

>100_bases
ATCTTCAAGCCATGGATTTCCTTTGCCGGGGCCACATGCTGGCCGACGTTTCGGCAATTCTTGGCTCGCTCGATATCGTG
TTTGGTGAGGTTGACCGCTG

Downstream 100 bases:

>100_bases
GACATGCTGGCTGACAAAGATCGCATCTTCACCAATATTTACGGCTTCAAGGATCAGTCCCTGAAGGGTGCCATGGCTCG
TGGCCATTGGGACAATACCA

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E 1; NDH-1 subunit E 1 [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MSVRRLADDAVQPATFAFNAENEAWAHKTIAKYPEGRQQSAVIPLLMRAQEQEGWVTKASIEYVAAMLNMPLIRVLEVAT
FYTQFQLKPVGSRAHIQVCGTTPCMLRGSEALMDVCRHKIHHDPFELNADGTLSWEEVECQGACANAPMVMIFKDAYEDL
TPERLAEIIDAFEAGKGDTIKPGPQDGRVTSEPASGLTALTKDLDYKKIGLETRKASDAAAAKAKAEAEAATKDGNR

Sequences:

>Translated_237_residues
MSVRRLADDAVQPATFAFNAENEAWAHKTIAKYPEGRQQSAVIPLLMRAQEQEGWVTKASIEYVAAMLNMPLIRVLEVAT
FYTQFQLKPVGSRAHIQVCGTTPCMLRGSEALMDVCRHKIHHDPFELNADGTLSWEEVECQGACANAPMVMIFKDAYEDL
TPERLAEIIDAFEAGKGDTIKPGPQDGRVTSEPASGLTALTKDLDYKKIGLETRKASDAAAAKAKAEAEAATKDGNR
>Mature_236_residues
SVRRLADDAVQPATFAFNAENEAWAHKTIAKYPEGRQQSAVIPLLMRAQEQEGWVTKASIEYVAAMLNMPLIRVLEVATF
YTQFQLKPVGSRAHIQVCGTTPCMLRGSEALMDVCRHKIHHDPFELNADGTLSWEEVECQGACANAPMVMIFKDAYEDLT
PERLAEIIDAFEAGKGDTIKPGPQDGRVTSEPASGLTALTKDLDYKKIGLETRKASDAAAAKAKAEAEAATKDGNR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=187, Percent_Identity=47.5935828877005, Blast_Score=173, Evalue=1e-43,
Organism=Escherichia coli, GI1788621, Length=165, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17561328, Length=199, Percent_Identity=43.21608040201, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI18859877, Length=197, Percent_Identity=43.1472081218274, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21355353, Length=186, Percent_Identity=34.9462365591398, Blast_Score=127, Evalue=5e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 25911; Mature: 25779

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVRRLADDAVQPATFAFNAENEAWAHKTIAKYPEGRQQSAVIPLLMRAQEQEGWVTKAS
CCHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEHHH
IEYVAAMLNMPLIRVLEVATFYTQFQLKPVGSRAHIQVCGTTPCMLRGSEALMDVCRHKI
HHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCEECCCHHHHHHHHHHH
HHDPFELNADGTLSWEEVECQGACANAPMVMIFKDAYEDLTPERLAEIIDAFEAGKGDTI
CCCCEEECCCCCCCHHHHEECCCCCCCCEEEEEECHHHCCCHHHHHHHHHHHHCCCCCCC
KPGPQDGRVTSEPASGLTALTKDLDYKKIGLETRKASDAAAAKAKAEAEAATKDGNR
CCCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVRRLADDAVQPATFAFNAENEAWAHKTIAKYPEGRQQSAVIPLLMRAQEQEGWVTKAS
CHHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEHHH
IEYVAAMLNMPLIRVLEVATFYTQFQLKPVGSRAHIQVCGTTPCMLRGSEALMDVCRHKI
HHHHHHHHCCHHHHHHHHHHHHHHEEEEECCCCEEEEECCCCCCEECCCHHHHHHHHHHH
HHDPFELNADGTLSWEEVECQGACANAPMVMIFKDAYEDLTPERLAEIIDAFEAGKGDTI
CCCCEEECCCCCCCHHHHEECCCCCCCCEEEEEECHHHCCCHHHHHHHHHHHHCCCCCCC
KPGPQDGRVTSEPASGLTALTKDLDYKKIGLETRKASDAAAAKAKAEAEAATKDGNR
CCCCCCCCCCCCCCCCHHHHHHCCCHHHHCCCHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]