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The map label for this gene is ctaA

Identifier: 225852301

GI number: 225852301

Start: 789153

End: 790229

Strand: Direct

Name: ctaA

Synonym: BMEA_A0825

Alternate gene names: 225852301

Gene position: 789153-790229 (Clockwise)

Preceding gene: 225852299

Following gene: 225852307

Centisome position: 37.12

GC content: 58.59

Gene sequence:

>1077_bases
ATGGCGGCAACATCGGCACAGCACATCGGCCTGCAAGGGCACGGAACATCCCGGAATGATCGTGACCGCCGCCTTGTGCG
CTACTGGCTCTATGCTGTCTTTGCCGTGCTGATTGCCATTGTCATGGTTGGCGGGGCCACCCGCATGACGGGCTCTGGCC
TTTCGATCACCGAATGGAAGCCGATCCATGGTGTCATTCCGCCGCTCAACCATGCCGAATGGGTGGAGGAATTTGAGAAA
TATCAGCAAATTCCCCAATATCAGCAGATCAACAAGGGCATGTCCCTTGCTGAGTTCCAGTATATTTTCTGGTGGGAATG
GGCGCATCGCCTGTTGGCGCGATTCGTGGGCTTTCTGGTTGCCGTTCCGCTGGGCTTTTTCTGGCTGACGGGCCGCCTGA
AGGGCGGGCTCAAATATCGTATGCTGGGTCTGCTCGCGCTTGGCGGGTTGCAGGGCGCTATCGGCTGGTGGATGGTTGCT
TCCGGCCTCAGCGAGCTTACCAGCGTCAGCCAGTACCGCCTCGCTATTCACCTCACCACGGCCTGCGTCATCATAACCGC
GGTTTTCTATATCGCGCGTGGGTTGGTCACTTACAGCGAGCGACCGGCAGAGCGTTCCATCCAGCGTTTTGCCGGCTGGA
TCGTGTTTGCGGTTCTGGTGCAGATCTATCTGGGCGGTCTGGTGGCCGGGCTGCACGCGGGATTGACCTATAACACTTGG
CCGTTGATGGATGGCGCAATCATCCCGTCAGACCTGTTCACACAGGCGCCGTGGTGGCGCAACCTGTTCGAGAATCCCAA
GACCGTGCAATTCGTGCACCGCATGTTTGCCTATACGGTTTTGCTGCTTGCCATTCTTCACGCGGTGCAGGTCTGGAAAA
ATGCACCGGGCACCACCCATGCGCGCCGCACCATCGTTCTGGTCGGCCTCGTTTTCATTCAGGCGATGATCGGCATTGCG
ACGCTTTTGATGAGTGCGCCGCTGCATCTGGGCCTGACGCACCAGTTTTTTGCTCTGGTGGTTCTGGCTTTCGCGGTGGC
GCACTGGCGCGCAACCAAGGGTGCCTATGCTGCATAG

Upstream 100 bases:

>100_bases
GAAAGGTTAAAACGCGGCGGCTTGTCGCGTGAACTTGTCTTGTAACCGCGTTCCCTATGCTGCATGTATCCTCGGCTTGA
TAAGAAAAAGGGTGAATGCA

Downstream 100 bases:

>100_bases
AGCGCATCCCGAAAAGTGTGAACGGTTTTCGGAAAAGATGCGCGTCAAAACAAAGGATTAGAGCGCCGATCTGATTCAAT
CAGATCAAAACGCGCTCCAA

Product: cytochrome oxidase assembly

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MAATSAQHIGLQGHGTSRNDRDRRLVRYWLYAVFAVLIAIVMVGGATRMTGSGLSITEWKPIHGVIPPLNHAEWVEEFEK
YQQIPQYQQINKGMSLAEFQYIFWWEWAHRLLARFVGFLVAVPLGFFWLTGRLKGGLKYRMLGLLALGGLQGAIGWWMVA
SGLSELTSVSQYRLAIHLTTACVIITAVFYIARGLVTYSERPAERSIQRFAGWIVFAVLVQIYLGGLVAGLHAGLTYNTW
PLMDGAIIPSDLFTQAPWWRNLFENPKTVQFVHRMFAYTVLLLAILHAVQVWKNAPGTTHARRTIVLVGLVFIQAMIGIA
TLLMSAPLHLGLTHQFFALVVLAFAVAHWRATKGAYAA

Sequences:

>Translated_358_residues
MAATSAQHIGLQGHGTSRNDRDRRLVRYWLYAVFAVLIAIVMVGGATRMTGSGLSITEWKPIHGVIPPLNHAEWVEEFEK
YQQIPQYQQINKGMSLAEFQYIFWWEWAHRLLARFVGFLVAVPLGFFWLTGRLKGGLKYRMLGLLALGGLQGAIGWWMVA
SGLSELTSVSQYRLAIHLTTACVIITAVFYIARGLVTYSERPAERSIQRFAGWIVFAVLVQIYLGGLVAGLHAGLTYNTW
PLMDGAIIPSDLFTQAPWWRNLFENPKTVQFVHRMFAYTVLLLAILHAVQVWKNAPGTTHARRTIVLVGLVFIQAMIGIA
TLLMSAPLHLGLTHQFFALVVLAFAVAHWRATKGAYAA
>Mature_357_residues
AATSAQHIGLQGHGTSRNDRDRRLVRYWLYAVFAVLIAIVMVGGATRMTGSGLSITEWKPIHGVIPPLNHAEWVEEFEKY
QQIPQYQQINKGMSLAEFQYIFWWEWAHRLLARFVGFLVAVPLGFFWLTGRLKGGLKYRMLGLLALGGLQGAIGWWMVAS
GLSELTSVSQYRLAIHLTTACVIITAVFYIARGLVTYSERPAERSIQRFAGWIVFAVLVQIYLGGLVAGLHAGLTYNTWP
LMDGAIIPSDLFTQAPWWRNLFENPKTVQFVHRMFAYTVLLLAILHAVQVWKNAPGTTHARRTIVLVGLVFIQAMIGIAT
LLMSAPLHLGLTHQFFALVVLAFAVAHWRATKGAYAA

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=357, Percent_Identity=37.5350140056022, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI17921987, Length=267, Percent_Identity=40.4494382022472, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17536069, Length=344, Percent_Identity=36.046511627907, Blast_Score=209, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6320989, Length=381, Percent_Identity=35.6955380577428, Blast_Score=207, Evalue=2e-54,
Organism=Drosophila melanogaster, GI19922860, Length=349, Percent_Identity=35.5300859598854, Blast_Score=185, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_BRUA1 (B2S532)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001934753.1
- GeneID:   6327915
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I07550
- HOGENOM:   HBG628966
- OMA:   GLSIVEW
- ProtClustDB:   CLSK2754107
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 40049; Mature: 39918

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: NA

Important sites: BINDING 334-334

Signals:

None

Transmembrane regions:

HASH(0x212ca884)-; HASH(0x21918490)-; HASH(0x21576f84)-; HASH(0x206d8030)-; HASH(0x21bc15d4)-; HASH(0x21bc149c)-; HASH(0x203ea89c)-; HASH(0x2176b87c)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATSAQHIGLQGHGTSRNDRDRRLVRYWLYAVFAVLIAIVMVGGATRMTGSGLSITEWK
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
PIHGVIPPLNHAEWVEEFEKYQQIPQYQQINKGMSLAEFQYIFWWEWAHRLLARFVGFLV
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVPLGFFWLTGRLKGGLKYRMLGLLALGGLQGAIGWWMVASGLSELTSVSQYRLAIHLTT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACVIITAVFYIARGLVTYSERPAERSIQRFAGWIVFAVLVQIYLGGLVAGLHAGLTYNTW
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PLMDGAIIPSDLFTQAPWWRNLFENPKTVQFVHRMFAYTVLLLAILHAVQVWKNAPGTTH
CCCCCCCCCHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ARRTIVLVGLVFIQAMIGIATLLMSAPLHLGLTHQFFALVVLAFAVAHWRATKGAYAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
AATSAQHIGLQGHGTSRNDRDRRLVRYWLYAVFAVLIAIVMVGGATRMTGSGLSITEWK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCC
PIHGVIPPLNHAEWVEEFEKYQQIPQYQQINKGMSLAEFQYIFWWEWAHRLLARFVGFLV
CCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AVPLGFFWLTGRLKGGLKYRMLGLLALGGLQGAIGWWMVASGLSELTSVSQYRLAIHLTT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ACVIITAVFYIARGLVTYSERPAERSIQRFAGWIVFAVLVQIYLGGLVAGLHAGLTYNTW
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PLMDGAIIPSDLFTQAPWWRNLFENPKTVQFVHRMFAYTVLLLAILHAVQVWKNAPGTTH
CCCCCCCCCHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
ARRTIVLVGLVFIQAMIGIATLLMSAPLHLGLTHQFFALVVLAFAVAHWRATKGAYAA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA