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The map label for this gene is cysS [H]

Identifier: 225852198

GI number: 225852198

Start: 682112

End: 683632

Strand: Direct

Name: cysS [H]

Synonym: BMEA_A0714

Alternate gene names: 225852198

Gene position: 682112-683632 (Clockwise)

Preceding gene: 225852195

Following gene: 225852199

Centisome position: 32.09

GC content: 59.17

Gene sequence:

>1521_bases
ATGCCGGATACCACGCCGCAATTGCGTCTTTATAATACGCTGACCCGCACGAAGGAGGCATTTGCCCCCATCGATGCGAA
GAATGTGCGCATGTATGTCTGCGGCCCGACGGTTTATGATTTTGCGCATATTGGCAATGCGCGCCCGGTGATCGTGTTCG
ACGTGCTGTTCCGTCTGTTGCGCCATGTTTACGGCGCGCAGCATGTCACCTATGCGCGCAACATTACCGATGTGGATGAC
AAGATCAATGCGCGCGCCGCGCGTGATTATCCCGATCTTCCCTTCAATGAAGCGATCCGCAAAGTCACCGAAAGCACCAA
TGCGCAGTTTCAGGCCGATGTGACCGCGCTTGGTAATCTTCAGCCCACGGTCCAGCCGCGCGCAACCGAACATATGGACG
AAATGCGCGCCATGATCGACCGGCTGGTGCAGCGCGGCGTGGCCTATGTGGCGCAAGATCATGTGCTCTTCTCGCCTTCG
GCCATGAATGCGCGCAAGGGGCCGCGCTATGGCGCGCTGGCCCGCCGCTCGCTCGATGAAATGCTGGCAGGCGCGCGCGT
CGATGTCGCGTCCTACAAGCGCGACGAGATGGATTTCGTGCTCTGGAAACCCTCGAAGAAAGGTGAACCGGGCTGGCCCT
CACCGGCTGGTATTGAAACTCTGGGCCGTCCGGGCTGGCATATCGAGTGCTCGGCCATGTCGATGGCCAAGCTTCTGGAG
CCGTTCGGCGGCGGGTTGAAATGCGACGACCCGGAAAGGAACCAGTTCGACATTCATGGCGGCGGTATCGATCTTGTCTT
TCCGCACCACGAAAACGAGATTGCCCAGTCCTGCTGCGCATTGGGAACCGAACGCATGGCCAATATCTGGATGCATAACG
GTTTTCTTCAGGTCGAGGGGCAGAAGATGTCGAAATCGCTCGGCAACTTCATCACCATCCGCGACGTGCTGAATGATGGC
CTGCCGCAATTGGGCGAGTGGGGCGATAATACGGTGCGCGACCGCTGGGCCGGTCTTGCGGCGCGCCTTTCCATGCTTCA
GACCCATTATCGCGAGCCGATCAACTGGACGGCGCAGCGTCTGGCGGAATCGGCTGATGAATTGCATCGCTGGTATGGCC
TACTGCGCGACGAAGGCTTTGGCGCGCCGGAAAAACTGTCTCACGCCAGTGCGGTTGCTGCGGCCCTTTGCGATGATCTT
AATAGCTGGGCGGCAATCACTGCCTTGCGTCAGGCGTTCAAGGTCAGGGACGTCGCTGCTCTGGGTGAGGGGATGGCGCT
GATGGGCCTGCTTGATCCTTATTTCGTGACGGCTTCCGATGTGCCGATCTTTGCCAGGGCAGATGTGGATGCGAGCGCCA
TTGCGGCGCGGATTGCGGAACGTCTGAACTTCATCAACGCGAAAAACTGGGCTGAGGCGGACCGCATTCGCGACGAGCTT
CTACAGGAAGGCGTGCAGTTGAAGGACAGCAAGGACCCTGCGACTGGCGAGCGCATAACGACATGGGATGTGGTAGGGTA
A

Upstream 100 bases:

>100_bases
GTTTTCGTCTCCCCTTCACAAAACAGGATGATAACGCCCCGGCCAGACGGCTGCGGTCTGTCGCGCCATCAGTTTCGCAG
GTCTTTAAAGGGGATTATCC

Downstream 100 bases:

>100_bases
TCGCGGGGGAGAACAATGATGGCACGCGAGCGCATTTATATTTACGATACGACCCTGCGGGATGGGCAGCAAACGCCCGG
CGTTGACTTCTCTGTGGAGG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MPDTTPQLRLYNTLTRTKEAFAPIDAKNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGAQHVTYARNITDVDD
KINARAARDYPDLPFNEAIRKVTESTNAQFQADVTALGNLQPTVQPRATEHMDEMRAMIDRLVQRGVAYVAQDHVLFSPS
AMNARKGPRYGALARRSLDEMLAGARVDVASYKRDEMDFVLWKPSKKGEPGWPSPAGIETLGRPGWHIECSAMSMAKLLE
PFGGGLKCDDPERNQFDIHGGGIDLVFPHHENEIAQSCCALGTERMANIWMHNGFLQVEGQKMSKSLGNFITIRDVLNDG
LPQLGEWGDNTVRDRWAGLAARLSMLQTHYREPINWTAQRLAESADELHRWYGLLRDEGFGAPEKLSHASAVAAALCDDL
NSWAAITALRQAFKVRDVAALGEGMALMGLLDPYFVTASDVPIFARADVDASAIAARIAERLNFINAKNWAEADRIRDEL
LQEGVQLKDSKDPATGERITTWDVVG

Sequences:

>Translated_506_residues
MPDTTPQLRLYNTLTRTKEAFAPIDAKNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGAQHVTYARNITDVDD
KINARAARDYPDLPFNEAIRKVTESTNAQFQADVTALGNLQPTVQPRATEHMDEMRAMIDRLVQRGVAYVAQDHVLFSPS
AMNARKGPRYGALARRSLDEMLAGARVDVASYKRDEMDFVLWKPSKKGEPGWPSPAGIETLGRPGWHIECSAMSMAKLLE
PFGGGLKCDDPERNQFDIHGGGIDLVFPHHENEIAQSCCALGTERMANIWMHNGFLQVEGQKMSKSLGNFITIRDVLNDG
LPQLGEWGDNTVRDRWAGLAARLSMLQTHYREPINWTAQRLAESADELHRWYGLLRDEGFGAPEKLSHASAVAAALCDDL
NSWAAITALRQAFKVRDVAALGEGMALMGLLDPYFVTASDVPIFARADVDASAIAARIAERLNFINAKNWAEADRIRDEL
LQEGVQLKDSKDPATGERITTWDVVG
>Mature_505_residues
PDTTPQLRLYNTLTRTKEAFAPIDAKNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGAQHVTYARNITDVDDK
INARAARDYPDLPFNEAIRKVTESTNAQFQADVTALGNLQPTVQPRATEHMDEMRAMIDRLVQRGVAYVAQDHVLFSPSA
MNARKGPRYGALARRSLDEMLAGARVDVASYKRDEMDFVLWKPSKKGEPGWPSPAGIETLGRPGWHIECSAMSMAKLLEP
FGGGLKCDDPERNQFDIHGGGIDLVFPHHENEIAQSCCALGTERMANIWMHNGFLQVEGQKMSKSLGNFITIRDVLNDGL
PQLGEWGDNTVRDRWAGLAARLSMLQTHYREPINWTAQRLAESADELHRWYGLLRDEGFGAPEKLSHASAVAAALCDDLN
SWAAITALRQAFKVRDVAALGEGMALMGLLDPYFVTASDVPIFARADVDASAIAARIAERLNFINAKNWAEADRIRDELL
QEGVQLKDSKDPATGERITTWDVVG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=400, Percent_Identity=35.5, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI21269877, Length=379, Percent_Identity=30.0791556728232, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI10835051, Length=379, Percent_Identity=30.0791556728232, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI62240992, Length=235, Percent_Identity=37.8723404255319, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI303304987, Length=235, Percent_Identity=37.8723404255319, Blast_Score=150, Evalue=2e-36,
Organism=Escherichia coli, GI1786737, Length=515, Percent_Identity=40.1941747572816, Blast_Score=302, Evalue=4e-83,
Organism=Caenorhabditis elegans, GI17509797, Length=340, Percent_Identity=32.9411764705882, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17509795, Length=340, Percent_Identity=32.9411764705882, Blast_Score=147, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324082, Length=354, Percent_Identity=29.9435028248588, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI19922218, Length=543, Percent_Identity=30.5709023941068, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI19922364, Length=341, Percent_Identity=33.1378299120235, Blast_Score=159, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56303; Mature: 56172

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTTPQLRLYNTLTRTKEAFAPIDAKNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCCCCCHHHHHHHHHH
RHVYGAQHVTYARNITDVDDKINARAARDYPDLPFNEAIRKVTESTNAQFQADVTALGNL
HHHHCCCHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHCCC
QPTVQPRATEHMDEMRAMIDRLVQRGVAYVAQDHVLFSPSAMNARKGPRYGALARRSLDE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHH
MLAGARVDVASYKRDEMDFVLWKPSKKGEPGWPSPAGIETLGRPGWHIECSAMSMAKLLE
HHCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCCCCEEEEHHHHHHHHHH
PFGGGLKCDDPERNQFDIHGGGIDLVFPHHENEIAQSCCALGTERMANIWMHNGFLQVEG
HCCCCCCCCCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
QKMSKSLGNFITIRDVLNDGLPQLGEWGDNTVRDRWAGLAARLSMLQTHYREPINWTAQR
HHHHHHHCCEEEHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAESADELHRWYGLLRDEGFGAPEKLSHASAVAAALCDDLNSWAAITALRQAFKVRDVAA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEGMALMGLLDPYFVTASDVPIFARADVDASAIAARIAERLNFINAKNWAEADRIRDEL
HCCCHHHHHHHCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LQEGVQLKDSKDPATGERITTWDVVG
HHCCCCCCCCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
PDTTPQLRLYNTLTRTKEAFAPIDAKNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLL
CCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHCCCCCCCHHHHHHHHHH
RHVYGAQHVTYARNITDVDDKINARAARDYPDLPFNEAIRKVTESTNAQFQADVTALGNL
HHHHCCCHHHHHCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHCCC
QPTVQPRATEHMDEMRAMIDRLVQRGVAYVAQDHVLFSPSAMNARKGPRYGALARRSLDE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHHHH
MLAGARVDVASYKRDEMDFVLWKPSKKGEPGWPSPAGIETLGRPGWHIECSAMSMAKLLE
HHCCCCCCHHHCCCCCCCEEEECCCCCCCCCCCCCCCHHHCCCCCCEEEEHHHHHHHHHH
PFGGGLKCDDPERNQFDIHGGGIDLVFPHHENEIAQSCCALGTERMANIWMHNGFLQVEG
HCCCCCCCCCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
QKMSKSLGNFITIRDVLNDGLPQLGEWGDNTVRDRWAGLAARLSMLQTHYREPINWTAQR
HHHHHHHCCEEEHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
LAESADELHRWYGLLRDEGFGAPEKLSHASAVAAALCDDLNSWAAITALRQAFKVRDVAA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEGMALMGLLDPYFVTASDVPIFARADVDASAIAARIAERLNFINAKNWAEADRIRDEL
HCCCHHHHHHHCCCEEECCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LQEGVQLKDSKDPATGERITTWDVVG
HHCCCCCCCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA