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The map label for this gene is uxuR [H]

Identifier: 225852089

GI number: 225852089

Start: 574718

End: 575395

Strand: Direct

Name: uxuR [H]

Synonym: BMEA_A0597

Alternate gene names: 225852089

Gene position: 574718-575395 (Clockwise)

Preceding gene: 225852085

Following gene: 225852090

Centisome position: 27.04

GC content: 60.32

Gene sequence:

>678_bases
ATGAAAACTATATCCAGAACCAATCTGACGGAATCGGCCATGCAGGCGATCCGGGCCGAAATTACTTCAGGCCGCTGGGT
GGTGGGCGAGAAATTGCCCAACGAAGCAGATCTCTCCGCGCGGCTTGGCTTCAGCCGGGGCACGGTGCGTGAGGCTGTGC
GCGCGCTGGTGGCGCAGGGAATGCTGGAAACGCGGCAGGGATCGGGCACCTATGTGCGCTCTGCCGCCGATACTGCGCGC
AGTCTGGATCGGATTCGCCATACGAGCTTGCGCGACCGTTTTGAAACGCGCGCGCTTCTGGAAACGGAAGCCGCGCGCCT
TGCTGCACAGCGCGCGACCCCCAAAATTATTGCACGCTTGAACAAGCTTCTGGATGAGAGGACGGGGCGCGCCGATATGG
ACCGGGCAACGTTTGTCGCGCGTGATTTCGCCTTCCATGAAGCAATCGTCGCGGCCTCCGGCAACAGTGCGCTTGCTGAA
ATTTATGCTTTTTTCTCGGCCTCGATTCGCGAATCCATTGAAGCCACGCTCGATGGCGGCCTGCCGGAACCGAGCGATGA
AGCACACCGCAGGATCGTCGAAGCCATTGCCACGGGCGATCCCGACAAGGCTGGCGCGACGGTGCGCAGCTTCATGGCCC
CCCTTATTGCAGAACTTGAAAGGTTGTTGGCATCATGA

Upstream 100 bases:

>100_bases
AACGGAATACGGCATAGGCCATCGCCTCGGCAAAAGGGGGCGTTGACAGGCAATATATTGGGATATGACTCATCAAGTCA
TCTGATGATTTTGGAAGACG

Downstream 100 bases:

>100_bases
GCCACGCAAGCGCCCTACCGCTGGACGGCCCGGCGGGAGACGATATTCTGGTGCGGTCACAGCCGCCTCTGATCGATGCC
GAGGCGGACAGTGTTCCCGC

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTISRTNLTESAMQAIRAEITSGRWVVGEKLPNEADLSARLGFSRGTVREAVRALVAQGMLETRQGSGTYVRSAADTAR
SLDRIRHTSLRDRFETRALLETEAARLAAQRATPKIIARLNKLLDERTGRADMDRATFVARDFAFHEAIVAASGNSALAE
IYAFFSASIRESIEATLDGGLPEPSDEAHRRIVEAIATGDPDKAGATVRSFMAPLIAELERLLAS

Sequences:

>Translated_225_residues
MKTISRTNLTESAMQAIRAEITSGRWVVGEKLPNEADLSARLGFSRGTVREAVRALVAQGMLETRQGSGTYVRSAADTAR
SLDRIRHTSLRDRFETRALLETEAARLAAQRATPKIIARLNKLLDERTGRADMDRATFVARDFAFHEAIVAASGNSALAE
IYAFFSASIRESIEATLDGGLPEPSDEAHRRIVEAIATGDPDKAGATVRSFMAPLIAELERLLAS
>Mature_225_residues
MKTISRTNLTESAMQAIRAEITSGRWVVGEKLPNEADLSARLGFSRGTVREAVRALVAQGMLETRQGSGTYVRSAADTAR
SLDRIRHTSLRDRFETRALLETEAARLAAQRATPKIIARLNKLLDERTGRADMDRATFVARDFAFHEAIVAASGNSALAE
IYAFFSASIRESIEATLDGGLPEPSDEAHRRIVEAIATGDPDKAGATVRSFMAPLIAELERLLAS

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789353, Length=220, Percent_Identity=31.3636363636364, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1790032, Length=210, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786303, Length=216, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI48994961, Length=225, Percent_Identity=27.5555555555556, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1789621, Length=222, Percent_Identity=27.9279279279279, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082208, Length=205, Percent_Identity=27.3170731707317, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 24500; Mature: 24500

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTISRTNLTESAMQAIRAEITSGRWVVGEKLPNEADLSARLGFSRGTVREAVRALVAQG
CCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
MLETRQGSGTYVRSAADTARSLDRIRHTSLRDRFETRALLETEAARLAAQRATPKIIARL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NKLLDERTGRADMDRATFVARDFAFHEAIVAASGNSALAEIYAFFSASIRESIEATLDGG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
LPEPSDEAHRRIVEAIATGDPDKAGATVRSFMAPLIAELERLLAS
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTISRTNLTESAMQAIRAEITSGRWVVGEKLPNEADLSARLGFSRGTVREAVRALVAQG
CCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
MLETRQGSGTYVRSAADTARSLDRIRHTSLRDRFETRALLETEAARLAAQRATPKIIARL
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
NKLLDERTGRADMDRATFVARDFAFHEAIVAASGNSALAEIYAFFSASIRESIEATLDGG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
LPEPSDEAHRRIVEAIATGDPDKAGATVRSFMAPLIAELERLLAS
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]