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The map label for this gene is epsC [H]

Identifier: 225852045

GI number: 225852045

Start: 529966

End: 531834

Strand: Direct

Name: epsC [H]

Synonym: BMEA_A0546

Alternate gene names: 225852045

Gene position: 529966-531834 (Clockwise)

Preceding gene: 225852044

Following gene: 225852047

Centisome position: 24.93

GC content: 56.88

Gene sequence:

>1869_bases
ATGAGTTTAAAATATCCTTGGCAAAGATTGGCGCTTCTGCCGCGCATCAGCAAACAGATCATTCTGGTGTTGAGCGATTG
CCTGTTGCTGCTTGCAAGCGCCTATCTAGCTTTTGTCGTCCGTTTCGGTTTCGTCTTCGTACCCAATCTGGCGCAGCTTT
TCCTGATCCTGATTGCGCCGCTTCTGGCCATTCCGGTCTTCATCCGTTTTGGGCTTTACCGCGCCATCATTCGTTATCTG
GCCGAGCGCGCCATCTGGTCGACCTTCCAGGCCACCGCAGTCGCCGCCTTGTTCTGGGTGGCGCTGGTGTTCCTGATGGA
GCTTTACGGCAGCACCGGCCTGCCGCGTTCTGTTCCGCTTCTTTATTGGCTCCTGAGTACGGTTTTCATTTCCGCAAGCC
GCTTCGGCGCAAAATGGCTGCTACGCACTGCCGAACACGACAAGCGGTATACCAGTTCAGCCCTGATAATCGGCATTGGC
GAACCGGCGCGTCAGCTTGCGACGGCCCTTCGCAGCCATAGCGATACGTTGGTGGTGGGTTTTATCGATCCTGCCGGGCA
ACTGGCCGGAATGGACATTATTGGCCTGCGTGTCTATCGCACGGAAGAAATTCCAAGCCTGATCGAAAATTACGGTATCA
AGCAGGTTGTCGTTTCAGAACCCGCGCTGGAGCAGAAGGAGCGCCAGGAGTTTGCGCGCCTTTTGGGGCGCCTGCCGGTC
AATACGCGCATTCTTCCGCCCATTGCTGATCTCACGGCCGGGAAATATCTCGTTAGTGCGCTGCGCAATGTCGAGATCGA
TGATCTTTTGGGGCGTTCGCCGGTTCCGCCTGATACAACGCTTCTGCGTGAGGTCGTGGAGGGGCGGCGCATCATGATAA
CCGGCGCGGGCGGTTCCATCGGCAGCCAGCTTTGCCTCACGATTGCGCAATGGAACCCGGCTGCGATTGTTCTCTTTGAA
TCGAGTGAGTTTGCATTATACCAGATCGACAGGCAGCTTCGCCAGTTTGCCTCTTGCACGGTGGTGCCGGTCCTTGGCTC
CGTGCGTGACCGCGCCTGCGTGGAAAAACCGATCCGCGATCATTCCATCGATACGGTTTATCACTGTGCGGCTTACAAGC
ATGTGCCGCTGGTGGAGAGGAACCCGCTGGTCGGCATTTTCAACAATGTATTCGGCACGCTGGAGGTGGCCGAGGCAGCG
TTGAACACGGATGTGGAACGCATGGTGCTGATCTCTTCCGACAAGGCCGTGCGCCCCACCAATGTCATGGGCGCGACCAA
GCGGTGGGCGGAACTGGTTGTCTATTATTACGGACGGCTGGCTGAGCAGGCCGGCAAGAAAAAAGCTTTCTATTCCGTCC
GTTCTGGCAATGTGCTTGGCTCCAACGGTTCGGTAGTGCCGCTTTTCCGCGAGCAGATTGCAAATGGCGGCCCCGTTACG
CTGACGCATGAAGACATGACGCGCTATTTCATGTCCATCAAGGAGGCGGCGGAACTGATCGTGCAGTCCGGCGCGATTGC
CCAATCCGGTGATACCGTTCTTTTGGAAATGGGTGAGCCGGTGAAAATCCGCGATCTGGCCGAAAACATGATCCTGCTCG
CGGGACTCACCGTGCGCAACGAGGAAAACCCGCAGGGCGATATCGCCATTGAGGTGACGGGTATTCGCGAAGGCGAGAAG
ATGTATGAAGAGCTTTTCTACGATCCTTCGCTCGCCCAGCGCACCCGTCATCCGAAAATCATGCGTGCGCCCCAGGGCAG
CAAGGCCGTGGTAGATATTCAGGAAAGCCTGGCGGTACTGCGGACCGCCATGGAAAAGGAGGATATCGAAATGGTCCGCA
AGGTGCTTTTCGAGGTCATCGCTTCCTGA

Upstream 100 bases:

>100_bases
ATCAACGTGGTTGCGTTCGATCTGACGGAATAGATAGGATTATTGCTCCGGCTTGCCGGGCTTAGTTTCTCTCCATCTGG
AGGGCGGGATTACAGCGCGT

Downstream 100 bases:

>100_bases
AGCGCCCGCGGAAATCGAGCAGCAGAATGAGTGTGGCAACGGCTGCGACCAGCAGAAATGTCAGTTGTGCGAGCGGATGA
TCCAGCGCCAGCAAGGCCAC

Product: polysaccharide biosynthesis protein CapD

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 621

Protein sequence:

>622_residues
MSLKYPWQRLALLPRISKQIILVLSDCLLLLASAYLAFVVRFGFVFVPNLAQLFLILIAPLLAIPVFIRFGLYRAIIRYL
AERAIWSTFQATAVAALFWVALVFLMELYGSTGLPRSVPLLYWLLSTVFISASRFGAKWLLRTAEHDKRYTSSALIIGIG
EPARQLATALRSHSDTLVVGFIDPAGQLAGMDIIGLRVYRTEEIPSLIENYGIKQVVVSEPALEQKERQEFARLLGRLPV
NTRILPPIADLTAGKYLVSALRNVEIDDLLGRSPVPPDTTLLREVVEGRRIMITGAGGSIGSQLCLTIAQWNPAAIVLFE
SSEFALYQIDRQLRQFASCTVVPVLGSVRDRACVEKPIRDHSIDTVYHCAAYKHVPLVERNPLVGIFNNVFGTLEVAEAA
LNTDVERMVLISSDKAVRPTNVMGATKRWAELVVYYYGRLAEQAGKKKAFYSVRSGNVLGSNGSVVPLFREQIANGGPVT
LTHEDMTRYFMSIKEAAELIVQSGAIAQSGDTVLLEMGEPVKIRDLAENMILLAGLTVRNEENPQGDIAIEVTGIREGEK
MYEELFYDPSLAQRTRHPKIMRAPQGSKAVVDIQESLAVLRTAMEKEDIEMVRKVLFEVIAS

Sequences:

>Translated_622_residues
MSLKYPWQRLALLPRISKQIILVLSDCLLLLASAYLAFVVRFGFVFVPNLAQLFLILIAPLLAIPVFIRFGLYRAIIRYL
AERAIWSTFQATAVAALFWVALVFLMELYGSTGLPRSVPLLYWLLSTVFISASRFGAKWLLRTAEHDKRYTSSALIIGIG
EPARQLATALRSHSDTLVVGFIDPAGQLAGMDIIGLRVYRTEEIPSLIENYGIKQVVVSEPALEQKERQEFARLLGRLPV
NTRILPPIADLTAGKYLVSALRNVEIDDLLGRSPVPPDTTLLREVVEGRRIMITGAGGSIGSQLCLTIAQWNPAAIVLFE
SSEFALYQIDRQLRQFASCTVVPVLGSVRDRACVEKPIRDHSIDTVYHCAAYKHVPLVERNPLVGIFNNVFGTLEVAEAA
LNTDVERMVLISSDKAVRPTNVMGATKRWAELVVYYYGRLAEQAGKKKAFYSVRSGNVLGSNGSVVPLFREQIANGGPVT
LTHEDMTRYFMSIKEAAELIVQSGAIAQSGDTVLLEMGEPVKIRDLAENMILLAGLTVRNEENPQGDIAIEVTGIREGEK
MYEELFYDPSLAQRTRHPKIMRAPQGSKAVVDIQESLAVLRTAMEKEDIEMVRKVLFEVIAS
>Mature_621_residues
SLKYPWQRLALLPRISKQIILVLSDCLLLLASAYLAFVVRFGFVFVPNLAQLFLILIAPLLAIPVFIRFGLYRAIIRYLA
ERAIWSTFQATAVAALFWVALVFLMELYGSTGLPRSVPLLYWLLSTVFISASRFGAKWLLRTAEHDKRYTSSALIIGIGE
PARQLATALRSHSDTLVVGFIDPAGQLAGMDIIGLRVYRTEEIPSLIENYGIKQVVVSEPALEQKERQEFARLLGRLPVN
TRILPPIADLTAGKYLVSALRNVEIDDLLGRSPVPPDTTLLREVVEGRRIMITGAGGSIGSQLCLTIAQWNPAAIVLFES
SEFALYQIDRQLRQFASCTVVPVLGSVRDRACVEKPIRDHSIDTVYHCAAYKHVPLVERNPLVGIFNNVFGTLEVAEAAL
NTDVERMVLISSDKAVRPTNVMGATKRWAELVVYYYGRLAEQAGKKKAFYSVRSGNVLGSNGSVVPLFREQIANGGPVTL
THEDMTRYFMSIKEAAELIVQSGAIAQSGDTVLLEMGEPVKIRDLAENMILLAGLTVRNEENPQGDIAIEVTGIREGEKM
YEELFYDPSLAQRTRHPKIMRAPQGSKAVVDIQESLAVLRTAMEKEDIEMVRKVLFEVIAS

Specific function: Involved in biofilm formation [H]

COG id: COG1086

COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polysaccharide synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003869 [H]

Pfam domain/function: PF02719 Polysacc_synt_2 [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 69035; Mature: 68903

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKYPWQRLALLPRISKQIILVLSDCLLLLASAYLAFVVRFGFVFVPNLAQLFLILIAP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAIPVFIRFGLYRAIIRYLAERAIWSTFQATAVAALFWVALVFLMELYGSTGLPRSVPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LYWLLSTVFISASRFGAKWLLRTAEHDKRYTSSALIIGIGEPARQLATALRSHSDTLVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCEEEEE
FIDPAGQLAGMDIIGLRVYRTEEIPSLIENYGIKQVVVSEPALEQKERQEFARLLGRLPV
EECCCCCCCCCEEEEEEEEECHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCC
NTRILPPIADLTAGKYLVSALRNVEIDDLLGRSPVPPDTTLLREVVEGRRIMITGAGGSI
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECCCCC
GSQLCLTIAQWNPAAIVLFESSEFALYQIDRQLRQFASCTVVPVLGSVRDRACVEKPIRD
CHHHHEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
HSIDTVYHCAAYKHVPLVERNPLVGIFNNVFGTLEVAEAALNTDVERMVLISSDKAVRPT
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
NVMGATKRWAELVVYYYGRLAEQAGKKKAFYSVRSGNVLGSNGSVVPLFREQIANGGPVT
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCEECCCCCEEHHHHHHCCCCCCEE
LTHEDMTRYFMSIKEAAELIVQSGAIAQSGDTVLLEMGEPVKIRDLAENMILLAGLTVRN
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEHHHHHHCCEEEECEEECC
EENPQGDIAIEVTGIREGEKMYEELFYDPSLAQRTRHPKIMRAPQGSKAVVDIQESLAVL
CCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHCCCCCEEECCCCCCHHHHHHHHHHHH
RTAMEKEDIEMVRKVLFEVIAS
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLKYPWQRLALLPRISKQIILVLSDCLLLLASAYLAFVVRFGFVFVPNLAQLFLILIAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAIPVFIRFGLYRAIIRYLAERAIWSTFQATAVAALFWVALVFLMELYGSTGLPRSVPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
LYWLLSTVFISASRFGAKWLLRTAEHDKRYTSSALIIGIGEPARQLATALRSHSDTLVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCEEEEE
FIDPAGQLAGMDIIGLRVYRTEEIPSLIENYGIKQVVVSEPALEQKERQEFARLLGRLPV
EECCCCCCCCCEEEEEEEEECHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCC
NTRILPPIADLTAGKYLVSALRNVEIDDLLGRSPVPPDTTLLREVVEGRRIMITGAGGSI
CCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCHHHHHHHHCCCEEEEEECCCCC
GSQLCLTIAQWNPAAIVLFESSEFALYQIDRQLRQFASCTVVPVLGSVRDRACVEKPIRD
CHHHHEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCC
HSIDTVYHCAAYKHVPLVERNPLVGIFNNVFGTLEVAEAALNTDVERMVLISSDKAVRPT
CCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
NVMGATKRWAELVVYYYGRLAEQAGKKKAFYSVRSGNVLGSNGSVVPLFREQIANGGPVT
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCEECCCCCEEHHHHHHCCCCCCEE
LTHEDMTRYFMSIKEAAELIVQSGAIAQSGDTVLLEMGEPVKIRDLAENMILLAGLTVRN
EEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEHHHHHHCCEEEECEEECC
EENPQGDIAIEVTGIREGEKMYEELFYDPSLAQRTRHPKIMRAPQGSKAVVDIQESLAVL
CCCCCCCEEEEEECCCCHHHHHHHHHCCCCHHHHCCCCCEEECCCCCCHHHHHHHHHHHH
RTAMEKEDIEMVRKVLFEVIAS
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969506; 9384377 [H]