Click here to switch to the map view.

The map label for this gene is ctaD [H]

Identifier: 225852004

GI number: 225852004

Start: 487339

End: 488997

Strand: Direct

Name: ctaD [H]

Synonym: BMEA_A0504

Alternate gene names: 225852004

Gene position: 487339-488997 (Clockwise)

Preceding gene: 225852003

Following gene: 225852005

Centisome position: 22.93

GC content: 59.8

Gene sequence:

>1659_bases
ATGGCTGGCACAGCAGCTCACGAGCATGGTGCCCACGACGACCACAAGCCGCATGGCTGGGTTCGTTGGGTATACTCGAC
CAATCATAAAGACATCGGTACCCTGTACCTGATTTTTGCAATCATCGCCGGCACCATCGGCGGCGCGCTTTCCATCGCGA
TGCGTGCCGAACTCCAGGAGCCGGGCATCCAGATTTTCCATGGTCTGGCGCAGATGGTTTACGGTGTTGAAGGCGATGCC
GCCCTTGATGCCGGCAAGCACATGTTCAACGTGTTCACCTCCGCGCACGCGCTCGTCATGATCTTCTTCATGGTCATGCC
TGCGCTGATCGGCGGTTTCGCCAACTGGATGGTGCCGCTCATGATCGGCGCGCCGGACATGGCGTTCCCACGCATGAACA
ATATTTCCTTCTGGCTGCTGCCGCCCGCGCTGATGCTGCTGCTGATCTCGCTGTTCATGCCCGGTCCGGCAGGTGGCTGG
GGCCCCGGCGGCGGCTGGACGCTCTATCCGCCGTTCTCGACCTCCGGCCAGCCCGGCCCGGCGGTGGATTTCGCCATTCT
GGCCATCCACATTTCCGGTGCCTCGTCGATCCTCGGCGCGATCAACTTCATTACGACGATCCTGAACATGCGCGCGCCGG
GCATGACGCTGCACAAGATGCCGCTCTTCGCCTGGGCCGTTCTGGTTACGGCGTTCCTGCTGCTCCTGTCGCTTCCGGTT
CTCGCAGGTGGTATCACCATGCTGCTTACCGACCGCAATTTCGGCACGACCTTCTTCGCGCCTGATGGCGGCGGCGACCC
GATCCTCTACCAGCACCTGTTCTGGTTCTTCGGCCATCCGGAAGTCTATATCCTGATCCAGCCGGGCTTCGGCATCGTCA
GCCATGTGGTCTCCACCTTCTCGCGCAAGCCGATCTTCGGTTATCTCGGCATGGCTTACGCCATGGTGGCAATCGGTGTC
GTCGGCTTTGTCGTCTGGGCCCACCACATGTACACGGTCGGCCTTTCGCTCGATACACAGCGCTACTTCGTCTTCGCCAC
GATGGTCATCGCGGTCCCGACAGGCATCAAGATCTTCTCGTGGATCGCGACGATGTGGGGTGGCTCGATTTCCTTCCGCG
CGCCCATGCTCTGGGCTATCGGCTTCATCTTCCTGTTCACCATCGGCGGTGTGACGGGTGTGCAGCTTGCAAATGCCGGT
CTCGACCGTGCATTGCACGATACCTATTATGTGGTGGCGCACTTCCACTATGTGCTGTCGCTTGGCGCTGTCTTCGCGAT
CTTTGCGGGCTGGTACTACTGGTTCCCGAAGATGAGCGGCTACATGTATAACGAGTTCACCGCAAAGCTGCATTTCTGGG
TCACGTTCGTCGGTGTGAACCTGGTCTTCTTCCCGCAGCACTTCCTGGGTCTCGCGGGCATGCCGCGCCGTTACATCGAC
TATCCGGATGCTTATGCCGGCTGGAACATGATTTCGTCATATGGCTCCTACATTTCAGGCTTTGCCGTGCTGATCTTCCT
CTATAACGTCTTCGAGGCGTTCGCGAAGAAGCGTGAAGCGGGTGCAAATCCGTGGGGCGATGGCGCGACCACGCTGGAAT
GGCAGCTTTCTTCGCCGCCGCCGTTCCACCAGTGGGAACAGCTCCCGCGCATCAAGTAA

Upstream 100 bases:

>100_bases
ATGGCGTTCTGAGCATTAGACCTGCGCACCGGGCTTTGCGAAGCCTATCCGGTTTCCGGGCCGATGCCGCAGCAAGACTT
GAAAAACGGGAGCGAATTCC

Downstream 100 bases:

>100_bases
TTGTGCGAGGGGCGGAGATCTCAAAAAACTTCGCCCCCGCCTGCAAATGTGCTAAGTGCGGGCGGCATTCTGTTTCGCCC
CGCCGCCGGCAAACGATGAG

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MAGTAAHEHGAHDDHKPHGWVRWVYSTNHKDIGTLYLIFAIIAGTIGGALSIAMRAELQEPGIQIFHGLAQMVYGVEGDA
ALDAGKHMFNVFTSAHALVMIFFMVMPALIGGFANWMVPLMIGAPDMAFPRMNNISFWLLPPALMLLLISLFMPGPAGGW
GPGGGWTLYPPFSTSGQPGPAVDFAILAIHISGASSILGAINFITTILNMRAPGMTLHKMPLFAWAVLVTAFLLLLSLPV
LAGGITMLLTDRNFGTTFFAPDGGGDPILYQHLFWFFGHPEVYILIQPGFGIVSHVVSTFSRKPIFGYLGMAYAMVAIGV
VGFVVWAHHMYTVGLSLDTQRYFVFATMVIAVPTGIKIFSWIATMWGGSISFRAPMLWAIGFIFLFTIGGVTGVQLANAG
LDRALHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMSGYMYNEFTAKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYID
YPDAYAGWNMISSYGSYISGFAVLIFLYNVFEAFAKKREAGANPWGDGATTLEWQLSSPPPFHQWEQLPRIK

Sequences:

>Translated_552_residues
MAGTAAHEHGAHDDHKPHGWVRWVYSTNHKDIGTLYLIFAIIAGTIGGALSIAMRAELQEPGIQIFHGLAQMVYGVEGDA
ALDAGKHMFNVFTSAHALVMIFFMVMPALIGGFANWMVPLMIGAPDMAFPRMNNISFWLLPPALMLLLISLFMPGPAGGW
GPGGGWTLYPPFSTSGQPGPAVDFAILAIHISGASSILGAINFITTILNMRAPGMTLHKMPLFAWAVLVTAFLLLLSLPV
LAGGITMLLTDRNFGTTFFAPDGGGDPILYQHLFWFFGHPEVYILIQPGFGIVSHVVSTFSRKPIFGYLGMAYAMVAIGV
VGFVVWAHHMYTVGLSLDTQRYFVFATMVIAVPTGIKIFSWIATMWGGSISFRAPMLWAIGFIFLFTIGGVTGVQLANAG
LDRALHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMSGYMYNEFTAKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYID
YPDAYAGWNMISSYGSYISGFAVLIFLYNVFEAFAKKREAGANPWGDGATTLEWQLSSPPPFHQWEQLPRIK
>Mature_551_residues
AGTAAHEHGAHDDHKPHGWVRWVYSTNHKDIGTLYLIFAIIAGTIGGALSIAMRAELQEPGIQIFHGLAQMVYGVEGDAA
LDAGKHMFNVFTSAHALVMIFFMVMPALIGGFANWMVPLMIGAPDMAFPRMNNISFWLLPPALMLLLISLFMPGPAGGWG
PGGGWTLYPPFSTSGQPGPAVDFAILAIHISGASSILGAINFITTILNMRAPGMTLHKMPLFAWAVLVTAFLLLLSLPVL
AGGITMLLTDRNFGTTFFAPDGGGDPILYQHLFWFFGHPEVYILIQPGFGIVSHVVSTFSRKPIFGYLGMAYAMVAIGVV
GFVVWAHHMYTVGLSLDTQRYFVFATMVIAVPTGIKIFSWIATMWGGSISFRAPMLWAIGFIFLFTIGGVTGVQLANAGL
DRALHDTYYVVAHFHYVLSLGAVFAIFAGWYYWFPKMSGYMYNEFTAKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYIDY
PDAYAGWNMISSYGSYISGFAVLIFLYNVFEAFAKKREAGANPWGDGATTLEWQLSSPPPFHQWEQLPRIK

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=528, Percent_Identity=60.4166666666667, Blast_Score=598, Evalue=1e-171,
Organism=Escherichia coli, GI1786634, Length=537, Percent_Identity=40.9683426443203, Blast_Score=385, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6226519, Length=547, Percent_Identity=55.2102376599634, Blast_Score=595, Evalue=1e-171,
Organism=Saccharomyces cerevisiae, GI6226524, Length=342, Percent_Identity=59.9415204678363, Blast_Score=403, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6226523, Length=266, Percent_Identity=53.0075187969925, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6226522, Length=94, Percent_Identity=41.4893617021277, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6226521, Length=81, Percent_Identity=41.9753086419753, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 60799; Mature: 60668

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGTAAHEHGAHDDHKPHGWVRWVYSTNHKDIGTLYLIFAIIAGTIGGALSIAMRAELQE
CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGIQIFHGLAQMVYGVEGDAALDAGKHMFNVFTSAHALVMIFFMVMPALIGGFANWMVPL
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIGAPDMAFPRMNNISFWLLPPALMLLLISLFMPGPAGGWGPGGGWTLYPPFSTSGQPGP
HCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCC
AVDFAILAIHISGASSILGAINFITTILNMRAPGMTLHKMPLFAWAVLVTAFLLLLSLPV
CCEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAGGITMLLTDRNFGTTFFAPDGGGDPILYQHLFWFFGHPEVYILIQPGFGIVSHVVSTF
HHCCEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
SRKPIFGYLGMAYAMVAIGVVGFVVWAHHMYTVGLSLDTQRYFVFATMVIAVPTGIKIFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHCCCHHHHH
WIATMWGGSISFRAPMLWAIGFIFLFTIGGVTGVQLANAGLDRALHDTYYVVAHFHYVLS
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAVFAIFAGWYYWFPKMSGYMYNEFTAKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYID
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
YPDAYAGWNMISSYGSYISGFAVLIFLYNVFEAFAKKREAGANPWGDGATTLEWQLSSPP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
PFHQWEQLPRIK
CCHHHHHCCCCC
>Mature Secondary Structure 
AGTAAHEHGAHDDHKPHGWVRWVYSTNHKDIGTLYLIFAIIAGTIGGALSIAMRAELQE
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGIQIFHGLAQMVYGVEGDAALDAGKHMFNVFTSAHALVMIFFMVMPALIGGFANWMVPL
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MIGAPDMAFPRMNNISFWLLPPALMLLLISLFMPGPAGGWGPGGGWTLYPPFSTSGQPGP
HCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCCCC
AVDFAILAIHISGASSILGAINFITTILNMRAPGMTLHKMPLFAWAVLVTAFLLLLSLPV
CCEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LAGGITMLLTDRNFGTTFFAPDGGGDPILYQHLFWFFGHPEVYILIQPGFGIVSHVVSTF
HHCCEEEEEECCCCCCEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
SRKPIFGYLGMAYAMVAIGVVGFVVWAHHMYTVGLSLDTQRYFVFATMVIAVPTGIKIFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHCCCHHHHH
WIATMWGGSISFRAPMLWAIGFIFLFTIGGVTGVQLANAGLDRALHDTYYVVAHFHYVLS
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGAVFAIFAGWYYWFPKMSGYMYNEFTAKLHFWVTFVGVNLVFFPQHFLGLAGMPRRYID
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCC
YPDAYAGWNMISSYGSYISGFAVLIFLYNVFEAFAKKREAGANPWGDGATTLEWQLSSPP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCC
PFHQWEQLPRIK
CCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2172930; 1965217; 12597275 [H]