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The map label for this gene is soxB [H]

Identifier: 225851756

GI number: 225851756

Start: 240181

End: 241434

Strand: Direct

Name: soxB [H]

Synonym: BMEA_A0237

Alternate gene names: 225851756

Gene position: 240181-241434 (Clockwise)

Preceding gene: 225851755

Following gene: 225851757

Centisome position: 11.3

GC content: 59.73

Gene sequence:

>1254_bases
ATGTCCCGCTTTTCTTTAGCTTCAGTCGTTAAAAATGCGCTTTCCGGCAACAGAAACTGGGAGCCGCAATGGCCCGATGC
CCAACCCAGGGCCGAATATGATGTCATCATCGTCGGTGCGGGCGGGCATGGCCTTGGCGCTGCCTATTATCTGGCCAAGG
AACACGGCATCACCAATGTCGCGGTTATCGAAAAGGGATGGCTCGGCGGTGGCAATACCGGGCGCAACACGACCATTATT
CGCTCCAACTATCTTTATGACGAGAGCGCGCATCTTTATGAACATGCGATGAAGCTCTGGGAGGGGCTGAGCCAGGATCT
CAATTATAATGTCATGTTCTCGCAGCGCGGCGTAATGATGCTGGCGCATACGATGCATGACGTGCAGAGTTTCAAGCGCC
ATATCCATGCCAACCGCCTCAACGGCATCGATAATGAATGGCTGACGAAAGAACAGGCGAAGGAATATTGTCCGCCGCTC
GATATCTCCCCTAATGCCCGTTATCCGGTGATTGGTGCAACCTTGCAGCGGCGCGGCGGCGTGGCCCGCCATGATGCGGT
TGCCTGGGGCTATGCGCGCGGTGCATCGCAGCGCGGCGTCGACATCATCCAGAACTGCCCGGTTCTGGCGATCCGCCGCG
ATGCTTCGGGCCGCGTGAGCGGCGTTGAAACGGCGCGGGGTTTCATCAAGGCGAAAAAGGTGGCGGTTTCGGCTGCGGGC
AACACCTCCGTCGTCATGGACACGGCAAGCGTGCGCATGCCGCTTGAAAGCTTCCCGCTACAGGCGCTGGTGTCGGAGCC
GGTCAAGCCGATTTTCCCCTGCGTGGTCATGTCGAACACGGTCCATGCCTATATCAGCCAGTCCGACAAGGGCGAACTGG
TGATCGGTTCGGGCACGGACCAATATGTGTCCTACAGCCAGCGCGGCGGCCTGCCGCTGATCGAGCATACGCTGGCTGCG
ATCTGTGAGGTCTTCCCGATCTTCACGCGCATGCGCATGTTGCGCAAATGGGGCGGCATCGTCGATGTCACGCCGGATCG
CTCGCCCATCATCGGCAAGACGCCGGTGCCGGGCCTTTATGTCAATTGCGGCTGGGGCACGGGCGGTTTCAAGGCGACGC
CGGGTTCAGCCCATGTCTTCGCCCATACGATTGCCCGCGATGAGCCGCACTGGATCAACGCGCCTTTCACGCTGGAACGC
TTCACTACCGGTCGCCTGATCGACGAAGCGGCTGCTGCCGCTGTTGCGCATTAA

Upstream 100 bases:

>100_bases
CAAGCCTGCTGTCGGCTTCTGGCGGGAGCCCATAAAATATCATCAAAGGCTTCGCGCGTGCCACAATGGTGTGCGGGGCT
GGTGAAAATGGTGGTTGTTC

Downstream 100 bases:

>100_bases
AGAATAGGGGAGACAAAAATGCTTCTTATCCGTTGCCCTTATTGCGAGATGGAACGCCCGGAACTCGAATTTGCCTATGC
GGGCGAAGCTCATATCGCGC

Product: sarcosine oxidase subunit beta family protein

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSRFSLASVVKNALSGNRNWEPQWPDAQPRAEYDVIIVGAGGHGLGAAYYLAKEHGITNVAVIEKGWLGGGNTGRNTTII
RSNYLYDESAHLYEHAMKLWEGLSQDLNYNVMFSQRGVMMLAHTMHDVQSFKRHIHANRLNGIDNEWLTKEQAKEYCPPL
DISPNARYPVIGATLQRRGGVARHDAVAWGYARGASQRGVDIIQNCPVLAIRRDASGRVSGVETARGFIKAKKVAVSAAG
NTSVVMDTASVRMPLESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTDQYVSYSQRGGLPLIEHTLAA
ICEVFPIFTRMRMLRKWGGIVDVTPDRSPIIGKTPVPGLYVNCGWGTGGFKATPGSAHVFAHTIARDEPHWINAPFTLER
FTTGRLIDEAAAAAVAH

Sequences:

>Translated_417_residues
MSRFSLASVVKNALSGNRNWEPQWPDAQPRAEYDVIIVGAGGHGLGAAYYLAKEHGITNVAVIEKGWLGGGNTGRNTTII
RSNYLYDESAHLYEHAMKLWEGLSQDLNYNVMFSQRGVMMLAHTMHDVQSFKRHIHANRLNGIDNEWLTKEQAKEYCPPL
DISPNARYPVIGATLQRRGGVARHDAVAWGYARGASQRGVDIIQNCPVLAIRRDASGRVSGVETARGFIKAKKVAVSAAG
NTSVVMDTASVRMPLESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTDQYVSYSQRGGLPLIEHTLAA
ICEVFPIFTRMRMLRKWGGIVDVTPDRSPIIGKTPVPGLYVNCGWGTGGFKATPGSAHVFAHTIARDEPHWINAPFTLER
FTTGRLIDEAAAAAVAH
>Mature_416_residues
SRFSLASVVKNALSGNRNWEPQWPDAQPRAEYDVIIVGAGGHGLGAAYYLAKEHGITNVAVIEKGWLGGGNTGRNTTIIR
SNYLYDESAHLYEHAMKLWEGLSQDLNYNVMFSQRGVMMLAHTMHDVQSFKRHIHANRLNGIDNEWLTKEQAKEYCPPLD
ISPNARYPVIGATLQRRGGVARHDAVAWGYARGASQRGVDIIQNCPVLAIRRDASGRVSGVETARGFIKAKKVAVSAAGN
TSVVMDTASVRMPLESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTDQYVSYSQRGGLPLIEHTLAAI
CEVFPIFTRMRMLRKWGGIVDVTPDRSPIIGKTPVPGLYVNCGWGTGGFKATPGSAHVFAHTIARDEPHWINAPFTLERF
TTGRLIDEAAAAAVAH

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI197927446, Length=386, Percent_Identity=24.3523316062176, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI21361378, Length=386, Percent_Identity=24.3523316062176, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI194306651, Length=385, Percent_Identity=23.3766233766234, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI24797151, Length=408, Percent_Identity=23.0392156862745, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI20130091, Length=386, Percent_Identity=23.5751295336788, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 45531; Mature: 45400

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFSLASVVKNALSGNRNWEPQWPDAQPRAEYDVIIVGAGGHGLGAAYYLAKEHGITNV
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHEEEHHHCCCCEE
AVIEKGWLGGGNTGRNTTIIRSNYLYDESAHLYEHAMKLWEGLSQDLNYNVMFSQRGVMM
EEEECCCCCCCCCCCCEEEEEECEEECCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
LAHTMHDVQSFKRHIHANRLNGIDNEWLTKEQAKEYCPPLDISPNARYPVIGATLQRRGG
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHCCCCCCCCCCCCCCEEHHHHHHCCC
VARHDAVAWGYARGASQRGVDIIQNCPVLAIRRDASGRVSGVETARGFIKAKKVAVSAAG
CCHHHHHHHHHHCCCCCCCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHEEEEEECC
NTSVVMDTASVRMPLESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTD
CCEEEEECHHHCCCHHHCCHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEECCCH
QYVSYSQRGGLPLIEHTLAAICEVFPIFTRMRMLRKWGGIVDVTPDRSPIIGKTPVPGLY
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEE
VNCGWGTGGFKATPGSAHVFAHTIARDEPHWINAPFTLERFTTGRLIDEAAAAAVAH
EECCCCCCCCCCCCCCCEEEEEEHHCCCCCEECCCEEEEHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SRFSLASVVKNALSGNRNWEPQWPDAQPRAEYDVIIVGAGGHGLGAAYYLAKEHGITNV
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHEEEHHHCCCCEE
AVIEKGWLGGGNTGRNTTIIRSNYLYDESAHLYEHAMKLWEGLSQDLNYNVMFSQRGVMM
EEEECCCCCCCCCCCCEEEEEECEEECCHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
LAHTMHDVQSFKRHIHANRLNGIDNEWLTKEQAKEYCPPLDISPNARYPVIGATLQRRGG
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHCCCCCCCCCCCCCCEEHHHHHHCCC
VARHDAVAWGYARGASQRGVDIIQNCPVLAIRRDASGRVSGVETARGFIKAKKVAVSAAG
CCHHHHHHHHHHCCCCCCCCHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHEEEEEECC
NTSVVMDTASVRMPLESFPLQALVSEPVKPIFPCVVMSNTVHAYISQSDKGELVIGSGTD
CCEEEEECHHHCCCHHHCCHHHHHHCCCHHHHHHHHHCCCEEEEEECCCCCCEEEECCCH
QYVSYSQRGGLPLIEHTLAAICEVFPIFTRMRMLRKWGGIVDVTPDRSPIIGKTPVPGLY
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCEE
VNCGWGTGGFKATPGSAHVFAHTIARDEPHWINAPFTLERFTTGRLIDEAAAAAVAH
EECCCCCCCCCCCCCCCEEEEEEHHCCCCCEECCCEEEEHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]