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The map label for this gene is sppA [C]

Identifier: 225851687

GI number: 225851687

Start: 170431

End: 171414

Strand: Reverse

Name: sppA [C]

Synonym: BMEA_A0160

Alternate gene names: 225851687

Gene position: 171414-170431 (Counterclockwise)

Preceding gene: 225851692

Following gene: 225851686

Centisome position: 8.06

GC content: 60.26

Gene sequence:

>984_bases
ATGGCTCATGACGCCGAAGCAATGATCGAAAGACGCAGGCTGCGCCGGAAGCTGACCAGCTGGCGATTGGCTTTCCTCGT
GCTTCTGGCCGCGCTGATAGCCGGGTTCGCCTTTTATTCGCTGCGCAGCGCCGAGTTTAACCAGCCGCATATCGCCAAGG
TGCGCATCGAGGGCACGATCTTCGAGAACGAGGAGCTTTTGAAGCGCCTCGACAAAATCGCCGGGGACGACGCCGTGAAG
GGTGTCATCCTGCTGCTCGATTCGCCGGGGGGCACCACCGTCGGCGGTGAAGCGATCTACGATGCCGTGCGCAAGATCGC
CACAAAGAAACCGGTCGTAACCCAGGTCGGCACGCTGGCCGCCTCCGCGGGCTATATGATCGCCAGCGCATCCGATCATA
TCGTGGCGCGGCAAACCTCCATTGTCGGCTCCATCGGCGTTCTCTTCCAGTATCCCGACCTTTCCAAACTGCTCGATACG
CTCGGCGTGAAGGTCGAAACCATCAAGTCCTCACCGCTGAAGGCCGAGCCCAATTATTTCAGCCCGGCGAGCGAGGAAGC
CAAGAACATGATCCGCAGCATGATCATGGATTCCTATGACTGGTTCGTCGGCATCGTGCAGGAACGCCGCGCCTTCACCC
ATGAACAGGCGCTGGCCCTTGCCAATGGCGCGGTGTTCACCGGGCGGCAGGCACTCGACAAAAAACTGATCGATGGCCTT
GGCGGCGAGGCGGAAGCCGTCGCATGGCTTCAGACCAAGGGACTGTCGGACAAGCTGCCTCGCCTTGAATGGAAGCCGGT
CGGCAGCGAAACAGGTTTTTCGCTGCGTGATCTCATCATCCATGCCGGCGCGCGCCTTCTGGGCCTGCCACAGGAAGCCG
ATGGCGCCATCAAGGAAATCGCCAGGGATCGCATCTTCCTTGACGGACTCCTTTCCGTTTGGCACGTTGATGGAATAGCC
GGTGCAAACCCGGCAAACCAGTAG

Upstream 100 bases:

>100_bases
TAAGGTTGAGAACAGGCTTAGAATCCACCGCCTTGGAGGCAGAAAGCGGAGAGTCAATTTTTCGCGATCAAGCCCTTATA
TTACAGATATGGACGAACGA

Downstream 100 bases:

>100_bases
AGTCCTTCCGGCAGGCAGGGCAGAATTGAAACAGGGGTCTAAAGCCGTGATCAAATCGGAACTTGTTCAGATTATCGCAA
GCCGCAATCCACATCTTTTC

Product: signal peptide peptidase SppA, 36K type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MAHDAEAMIERRRLRRKLTSWRLAFLVLLAALIAGFAFYSLRSAEFNQPHIAKVRIEGTIFENEELLKRLDKIAGDDAVK
GVILLLDSPGGTTVGGEAIYDAVRKIATKKPVVTQVGTLAASAGYMIASASDHIVARQTSIVGSIGVLFQYPDLSKLLDT
LGVKVETIKSSPLKAEPNYFSPASEEAKNMIRSMIMDSYDWFVGIVQERRAFTHEQALALANGAVFTGRQALDKKLIDGL
GGEAEAVAWLQTKGLSDKLPRLEWKPVGSETGFSLRDLIIHAGARLLGLPQEADGAIKEIARDRIFLDGLLSVWHVDGIA
GANPANQ

Sequences:

>Translated_327_residues
MAHDAEAMIERRRLRRKLTSWRLAFLVLLAALIAGFAFYSLRSAEFNQPHIAKVRIEGTIFENEELLKRLDKIAGDDAVK
GVILLLDSPGGTTVGGEAIYDAVRKIATKKPVVTQVGTLAASAGYMIASASDHIVARQTSIVGSIGVLFQYPDLSKLLDT
LGVKVETIKSSPLKAEPNYFSPASEEAKNMIRSMIMDSYDWFVGIVQERRAFTHEQALALANGAVFTGRQALDKKLIDGL
GGEAEAVAWLQTKGLSDKLPRLEWKPVGSETGFSLRDLIIHAGARLLGLPQEADGAIKEIARDRIFLDGLLSVWHVDGIA
GANPANQ
>Mature_326_residues
AHDAEAMIERRRLRRKLTSWRLAFLVLLAALIAGFAFYSLRSAEFNQPHIAKVRIEGTIFENEELLKRLDKIAGDDAVKG
VILLLDSPGGTTVGGEAIYDAVRKIATKKPVVTQVGTLAASAGYMIASASDHIVARQTSIVGSIGVLFQYPDLSKLLDTL
GVKVETIKSSPLKAEPNYFSPASEEAKNMIRSMIMDSYDWFVGIVQERRAFTHEQALALANGAVFTGRQALDKKLIDGLG
GEAEAVAWLQTKGLSDKLPRLEWKPVGSETGFSLRDLIIHAGARLLGLPQEADGAIKEIARDRIFLDGLLSVWHVDGIAG
ANPANQ

Specific function: Digestion Of The Cleaved Signal Peptides. This Activity Is Necessary To Maintain Proper Secretion Of Mature Proteins Across The Membrane. [C]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=220, Percent_Identity=31.8181818181818, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787527, Length=192, Percent_Identity=29.1666666666667, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004635
- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 35547; Mature: 35416

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHDAEAMIERRRLRRKLTSWRLAFLVLLAALIAGFAFYSLRSAEFNQPHIAKVRIEGTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEE
FENEELLKRLDKIAGDDAVKGVILLLDSPGGTTVGGEAIYDAVRKIATKKPVVTQVGTLA
ECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
ASAGYMIASASDHIVARQTSIVGSIGVLFQYPDLSKLLDTLGVKVETIKSSPLKAEPNYF
HHCCEEEECCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHCCEEEEECCCCCCCCCCCC
SPASEEAKNMIRSMIMDSYDWFVGIVQERRAFTHEQALALANGAVFTGRQALDKKLIDGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHCC
GGEAEAVAWLQTKGLSDKLPRLEWKPVGSETGFSLRDLIIHAGARLLGLPQEADGAIKEI
CCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHH
ARDRIFLDGLLSVWHVDGIAGANPANQ
HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AHDAEAMIERRRLRRKLTSWRLAFLVLLAALIAGFAFYSLRSAEFNQPHIAKVRIEGTI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEE
FENEELLKRLDKIAGDDAVKGVILLLDSPGGTTVGGEAIYDAVRKIATKKPVVTQVGTLA
ECCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHH
ASAGYMIASASDHIVARQTSIVGSIGVLFQYPDLSKLLDTLGVKVETIKSSPLKAEPNYF
HHCCEEEECCCCCHHHHHHHHHHHHHHEEECCCHHHHHHHHCCEEEEECCCCCCCCCCCC
SPASEEAKNMIRSMIMDSYDWFVGIVQERRAFTHEQALALANGAVFTGRQALDKKLIDGL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCHHHHHHHHHHCC
GGEAEAVAWLQTKGLSDKLPRLEWKPVGSETGFSLRDLIIHAGARLLGLPQEADGAIKEI
CCCHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHH
ARDRIFLDGLLSVWHVDGIAGANPANQ
HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]