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The map label for this gene is pgm [H]

Identifier: 225851599

GI number: 225851599

Start: 64817

End: 66448

Strand: Reverse

Name: pgm [H]

Synonym: BMEA_A0059

Alternate gene names: 225851599

Gene position: 66448-64817 (Counterclockwise)

Preceding gene: 225851600

Following gene: 225851597

Centisome position: 3.13

GC content: 57.84

Gene sequence:

>1632_bases
ATGACCGTCAAGACCATTGCGACCACGCCATACCAGGATCAACAGCCGGGCACTTCGGGCTTGCGCAAGAAGGTTCCGGT
TTTCCAGCAGCCCAATTATGCAGAAAATTTCATCCAGTCGATCTTCGACGTGCTGGAGGGGTTCAAGGGCAAGACGCTCG
TGGTTGGCGGCGACGGACGCTTTTATAACCGCGAGGTGATCCAGAAGCTTATCAAGATCGCAGCCGCCAACGGTTTTGGC
CGTATCATGGTGGGACAGGGCGGCATTCTTTCCACGCCAGCCGCCTCCAACATGATCCGCAAGTACAAAGCCTTCGGTGG
CATGATCCTTTCGGCCAGCCACAATCCGGGCGGGCCTACGCAGGATTTCGGCATCAAGTACAATATCGGCAATGGTGGAC
CGGCACCCGAAAAGATCACCGAAGCGATCTTCGCCCGCTCAAAGGTGATCGACCAGTATAAAATTGCAGATGCAGCCGAT
ATCGATATCGACAAGATCGGCACAAGCAAGATCGGCGATACCGAGGTGGTCATCTTCGATCCGGTGGCCGATTATGCTGA
ATTGATGGAAAGCCTGTTCGATTTCGCCGCCATCCGCGCCATGATAAAAGGCGGCTTCCAGATGAAGTTCGACGCCATGC
ATGCGGTGACCGGGCCTTATGCCAAGGAAATCTTCGAGCGCCGCCTCGGTGCGCCCGAAGGCAGCGTCGTCAATTTCGTG
CCCCTGCCGGATTTCGGTGGCCATCACCCGGATCCAAACCTCGTCTATGCCAAGGATCTCTACGATCTTCTGATGTCCAG
CCATGCGCCGGATTTTGGCGCCGCCTCCGACGGCGATGGCGATCGCAACCTCATTCTCGGGCGCGGTATCTTCATCACGC
CGTCAGATTCGCTTGCCATGCTGGCCGCAAATGCCCATCTGGCGCCGGGCTATAAAGGCGGTATCAAGGGCATTGCCCGT
TCCATGCCGACGAGCGCCGCCGCCGACCGCGTGGCGGAAAAACTCGGTATCGGCATGTATGAAACCCCGACCGGCTGGAA
ATTCTTCGGCAATCTTCTCGACAGCGGCAAGGTGACGATCTGCGGCGAGGAAAGCTCCGGCACCGGCTCCGACCATGTGC
GCGAAAAAGATGGTTTGTGGGCCGTTCTGCTCTGGCTCAACATTCTGGCGGTGCGCAAGGAAAGTGTGAAGGCAATCGCG
GACGACCATTGGGCACGTTTCGGGCGCAATTATTACACTCGCCACGACTATGAAGCCGTCGATTCCGATATTGCGACGAA
GCTGGTGGCTGACCTGCGCGGCAAGCTTGCCGGCCTGCCCGGCACGAGCGTCAATGGCCTCAGGATCGAAAAGGCCGACG
ACTTCGCCTATCATGATCCCGTTGATGGCTCGACCAGCGAACATCAGGGCATCCGCATCTATTTTGAAGGAGGTGCGCGC
ATCGTGCTTCGCCTGTCCGGTACCGGGACGTCAGGCGCGACCATCCGCATCTATATCGAACGCTATGAAGCCGATCCTGC
AAAACATAATCTCGACACGCAGGCAACGCTGGCCCCACTGATCGACGCGGCTGAACAGATCGCCGAAGTAAAAAAACGCA
GCGGGCGGACAGAGCCGTCGGTGGTTACTTGA

Upstream 100 bases:

>100_bases
TGTTATTTTCAAACAACAAGTTTGATCTATCTTGTCTTGCAATGACCGCAAACACCGACAAGGTGCACGGTGCCAACCGA
TTGAAACGAACGGGAACAAC

Downstream 100 bases:

>100_bases
GTAGGGCAGTAGGGCAGTAGGGCAGTAGGGCAGTAGGGCAGTAGGGCAGTAGGGCAGTAGGGCAGTAGGGCAGTAGGGCA
GTAGGGCAGTAGGGCAGTGA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MTVKTIATTPYQDQQPGTSGLRKKVPVFQQPNYAENFIQSIFDVLEGFKGKTLVVGGDGRFYNREVIQKLIKIAAANGFG
RIMVGQGGILSTPAASNMIRKYKAFGGMILSASHNPGGPTQDFGIKYNIGNGGPAPEKITEAIFARSKVIDQYKIADAAD
IDIDKIGTSKIGDTEVVIFDPVADYAELMESLFDFAAIRAMIKGGFQMKFDAMHAVTGPYAKEIFERRLGAPEGSVVNFV
PLPDFGGHHPDPNLVYAKDLYDLLMSSHAPDFGAASDGDGDRNLILGRGIFITPSDSLAMLAANAHLAPGYKGGIKGIAR
SMPTSAAADRVAEKLGIGMYETPTGWKFFGNLLDSGKVTICGEESSGTGSDHVREKDGLWAVLLWLNILAVRKESVKAIA
DDHWARFGRNYYTRHDYEAVDSDIATKLVADLRGKLAGLPGTSVNGLRIEKADDFAYHDPVDGSTSEHQGIRIYFEGGAR
IVLRLSGTGTSGATIRIYIERYEADPAKHNLDTQATLAPLIDAAEQIAEVKKRSGRTEPSVVT

Sequences:

>Translated_543_residues
MTVKTIATTPYQDQQPGTSGLRKKVPVFQQPNYAENFIQSIFDVLEGFKGKTLVVGGDGRFYNREVIQKLIKIAAANGFG
RIMVGQGGILSTPAASNMIRKYKAFGGMILSASHNPGGPTQDFGIKYNIGNGGPAPEKITEAIFARSKVIDQYKIADAAD
IDIDKIGTSKIGDTEVVIFDPVADYAELMESLFDFAAIRAMIKGGFQMKFDAMHAVTGPYAKEIFERRLGAPEGSVVNFV
PLPDFGGHHPDPNLVYAKDLYDLLMSSHAPDFGAASDGDGDRNLILGRGIFITPSDSLAMLAANAHLAPGYKGGIKGIAR
SMPTSAAADRVAEKLGIGMYETPTGWKFFGNLLDSGKVTICGEESSGTGSDHVREKDGLWAVLLWLNILAVRKESVKAIA
DDHWARFGRNYYTRHDYEAVDSDIATKLVADLRGKLAGLPGTSVNGLRIEKADDFAYHDPVDGSTSEHQGIRIYFEGGAR
IVLRLSGTGTSGATIRIYIERYEADPAKHNLDTQATLAPLIDAAEQIAEVKKRSGRTEPSVVT
>Mature_542_residues
TVKTIATTPYQDQQPGTSGLRKKVPVFQQPNYAENFIQSIFDVLEGFKGKTLVVGGDGRFYNREVIQKLIKIAAANGFGR
IMVGQGGILSTPAASNMIRKYKAFGGMILSASHNPGGPTQDFGIKYNIGNGGPAPEKITEAIFARSKVIDQYKIADAADI
DIDKIGTSKIGDTEVVIFDPVADYAELMESLFDFAAIRAMIKGGFQMKFDAMHAVTGPYAKEIFERRLGAPEGSVVNFVP
LPDFGGHHPDPNLVYAKDLYDLLMSSHAPDFGAASDGDGDRNLILGRGIFITPSDSLAMLAANAHLAPGYKGGIKGIARS
MPTSAAADRVAEKLGIGMYETPTGWKFFGNLLDSGKVTICGEESSGTGSDHVREKDGLWAVLLWLNILAVRKESVKAIAD
DHWARFGRNYYTRHDYEAVDSDIATKLVADLRGKLAGLPGTSVNGLRIEKADDFAYHDPVDGSTSEHQGIRIYFEGGARI
VLRLSGTGTSGATIRIYIERYEADPAKHNLDTQATLAPLIDAAEQIAEVKKRSGRTEPSVVT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI21361621, Length=562, Percent_Identity=55.338078291815, Blast_Score=621, Evalue=1e-178,
Organism=Homo sapiens, GI290463102, Length=562, Percent_Identity=54.4483985765125, Blast_Score=613, Evalue=1e-176,
Organism=Homo sapiens, GI133922562, Length=563, Percent_Identity=47.7797513321492, Blast_Score=537, Evalue=1e-152,
Organism=Homo sapiens, GI290463104, Length=366, Percent_Identity=55.1912568306011, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI239741729, Length=135, Percent_Identity=47.4074074074074, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI239743670, Length=135, Percent_Identity=45.9259259259259, Blast_Score=116, Evalue=6e-26,
Organism=Escherichia coli, GI1786904, Length=377, Percent_Identity=27.3209549071618, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17535441, Length=567, Percent_Identity=49.5590828924162, Blast_Score=534, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6323752, Length=567, Percent_Identity=48.8536155202822, Blast_Score=524, Evalue=1e-149,
Organism=Saccharomyces cerevisiae, GI6322722, Length=570, Percent_Identity=47.0175438596491, Blast_Score=503, Evalue=1e-143,
Organism=Drosophila melanogaster, GI17864244, Length=563, Percent_Identity=50.088809946714, Blast_Score=566, Evalue=1e-161,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58601; Mature: 58470

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKTIATTPYQDQQPGTSGLRKKVPVFQQPNYAENFIQSIFDVLEGFKGKTLVVGGDGR
CCEEEEECCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCC
FYNREVIQKLIKIAAANGFGRIMVGQGGILSTPAASNMIRKYKAFGGMILSASHNPGGPT
EECHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCC
QDFGIKYNIGNGGPAPEKITEAIFARSKVIDQYKIADAADIDIDKIGTSKIGDTEVVIFD
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEEEC
PVADYAELMESLFDFAAIRAMIKGGFQMKFDAMHAVTGPYAKEIFERRLGAPEGSVVNFV
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHCCCCCCCEEEEE
PLPDFGGHHPDPNLVYAKDLYDLLMSSHAPDFGAASDGDGDRNLILGRGIFITPSDSLAM
ECCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCEEECCCCCEEE
LAANAHLAPGYKGGIKGIARSMPTSAAADRVAEKLGIGMYETPTGWKFFGNLLDSGKVTI
EEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCEEE
CGEESSGTGSDHVREKDGLWAVLLWLNILAVRKESVKAIADDHWARFGRNYYTRHDYEAV
ECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
DSDIATKLVADLRGKLAGLPGTSVNGLRIEKADDFAYHDPVDGSTSEHQGIRIYFEGGAR
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCE
IVLRLSGTGTSGATIRIYIERYEADPAKHNLDTQATLAPLIDAAEQIAEVKKRSGRTEPS
EEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
VVT
CCC
>Mature Secondary Structure 
TVKTIATTPYQDQQPGTSGLRKKVPVFQQPNYAENFIQSIFDVLEGFKGKTLVVGGDGR
CEEEEECCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCC
FYNREVIQKLIKIAAANGFGRIMVGQGGILSTPAASNMIRKYKAFGGMILSASHNPGGPT
EECHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCC
QDFGIKYNIGNGGPAPEKITEAIFARSKVIDQYKIADAADIDIDKIGTSKIGDTEVVIFD
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCEEEEEEC
PVADYAELMESLFDFAAIRAMIKGGFQMKFDAMHAVTGPYAKEIFERRLGAPEGSVVNFV
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHCCHHHHHHHHHHCCCCCCCEEEEE
PLPDFGGHHPDPNLVYAKDLYDLLMSSHAPDFGAASDGDGDRNLILGRGIFITPSDSLAM
ECCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCEEECCCCCEEE
LAANAHLAPGYKGGIKGIARSMPTSAAADRVAEKLGIGMYETPTGWKFFGNLLDSGKVTI
EEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHCCCCEEE
CGEESSGTGSDHVREKDGLWAVLLWLNILAVRKESVKAIADDHWARFGRNYYTRHDYEAV
ECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
DSDIATKLVADLRGKLAGLPGTSVNGLRIEKADDFAYHDPVDGSTSEHQGIRIYFEGGAR
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCE
IVLRLSGTGTSGATIRIYIERYEADPAKHNLDTQATLAPLIDAAEQIAEVKKRSGRTEPS
EEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
VVT
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]