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The map label for this gene is dgdA [H]

Identifier: 225686908

GI number: 225686908

Start: 1142457

End: 1143740

Strand: Reverse

Name: dgdA [H]

Synonym: BMEA_B1160

Alternate gene names: 225686908

Gene position: 1143740-1142457 (Counterclockwise)

Preceding gene: 225686909

Following gene: 225686907

Centisome position: 96.48

GC content: 59.42

Gene sequence:

>1284_bases
ATGAGCGGAAATCAGGAAATGATTGCCCGCAGGGAGCGGCTGCTTGGCCGCAACATGTCCCTATTTTATCAGGACCCGGT
GCATCTGGTGAAGGGTGAGGGTGTCTGGCTCTGGGATGCGGACGGGCGCAAATATCTCGATTGCTATAACAATGTGCCGC
ATGTGGGCCATTGCCATCCGCGTGTGGTGGAGGCGATCTGCCGTCAGGCTTCGACCCTCAACACCCATACGCGCTATCTG
CATGAAGGAATTCTGGATTATGTCGAACGGCTGACAGCGACTTTCGACAAAAGCCTCGATGCGGCAATTCTCACCTGCAC
CGGCAGCGAGGCGAATGACGTGGCCCTGCACATGGCGCAGGCGGTAACGGGCAAGACCGGCATCATCGCAACCGACTTCA
CCTATCACGGCAATACGACGGCGGTTTCGCAGCTTTCGACGCGAATGCCGCCGGTGGGCGGCTATGGCGGTCATGTGCGC
CATGTGCCGGCACCCGACAGCTATCGCCCGCTTGGCGGTAAGGGGGGCGAAGCCTTCGCGCAAGCGTGGGCGGCGGAGGT
GGAAAAGGCCATCGCTTCGTTGCAGGAAAGCCCGTTCGGCTTTTCCGGCCTTATCATCGATCCGTTCTTTGCCAATGAAG
GTTTCCCCGATCTGCCGGAAAATTTTCTGGCTCCCGCCGTCGCTGCGGTCAGAAAGGCGGGCGGTGTGGTGATTGCCGAC
GAGGTGCAGCCGGGTTTCGGACGCACGGGCGGGCATATGTGGGGGCACCAGAAGGCGGGCATCGTGCCGGATATCGTGAC
ACTCGGCAAACCGATGGGCAATGGCCATCCGGTTGGCGCGGTGGTTGCCGGTGCGGATACGCTGAATGCGTTCCGCAAGG
CTTTCCGCTATTTCAACACTTTTGGCGGCAATCCGGTTTCCTGTGCTGCGGCAATGGCTGTGCTCGACGTGCTGGAGGAG
GAAAAACTACAGGCCAATGCGTTGGAAGTCGGCGCTTATGCACGTCAGGGGCTGGAAAAACTGGCCCAGAAACATGGTAT
GATCGGCAATGTTCGCGGCAGCGGGCTGTTTTTCGGTGCGGAACTTGTTCTCGATCGGGCGGAAAAAACTCCGGCGGCAG
AGATGGCCACGCGGGTTGTGAACGAAATGCGCGAACGCGGCGTGCTGATGAACAAGCTCGGCATCCACCAGAACGCCACC
AAGATCAGGCCGCCCATGCCGTTTTCCAGAGAGAATGCAGATCTCATGCTTTCCACGCTGGATGATGTTCTGGGCGGATT
GTGA

Upstream 100 bases:

>100_bases
AATGTCATCATTTCGCCGCCGCTTGTCATCACGCCTGCCGATGTGAACCGCATTGTTTCTGCGCTCGATGCTGGCCTTTC
CGCCGCGAAGGGACAATGAC

Downstream 100 bases:

>100_bases
CGCGATGGAAAAGTGTCTCGACCATCTGACACAGCGCGTCTCTGCCGCTCTTGCCTTCTGGGGTTTGCCGGAACAGATGC
CGGAACTTCTGAAATATCGT

Product: aminotransferase class-III protein

Products: NA

Alternate protein names: DGD [H]

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSGNQEMIARRERLLGRNMSLFYQDPVHLVKGEGVWLWDADGRKYLDCYNNVPHVGHCHPRVVEAICRQASTLNTHTRYL
HEGILDYVERLTATFDKSLDAAILTCTGSEANDVALHMAQAVTGKTGIIATDFTYHGNTTAVSQLSTRMPPVGGYGGHVR
HVPAPDSYRPLGGKGGEAFAQAWAAEVEKAIASLQESPFGFSGLIIDPFFANEGFPDLPENFLAPAVAAVRKAGGVVIAD
EVQPGFGRTGGHMWGHQKAGIVPDIVTLGKPMGNGHPVGAVVAGADTLNAFRKAFRYFNTFGGNPVSCAAAMAVLDVLEE
EKLQANALEVGAYARQGLEKLAQKHGMIGNVRGSGLFFGAELVLDRAEKTPAAEMATRVVNEMRERGVLMNKLGIHQNAT
KIRPPMPFSRENADLMLSTLDDVLGGL

Sequences:

>Translated_427_residues
MSGNQEMIARRERLLGRNMSLFYQDPVHLVKGEGVWLWDADGRKYLDCYNNVPHVGHCHPRVVEAICRQASTLNTHTRYL
HEGILDYVERLTATFDKSLDAAILTCTGSEANDVALHMAQAVTGKTGIIATDFTYHGNTTAVSQLSTRMPPVGGYGGHVR
HVPAPDSYRPLGGKGGEAFAQAWAAEVEKAIASLQESPFGFSGLIIDPFFANEGFPDLPENFLAPAVAAVRKAGGVVIAD
EVQPGFGRTGGHMWGHQKAGIVPDIVTLGKPMGNGHPVGAVVAGADTLNAFRKAFRYFNTFGGNPVSCAAAMAVLDVLEE
EKLQANALEVGAYARQGLEKLAQKHGMIGNVRGSGLFFGAELVLDRAEKTPAAEMATRVVNEMRERGVLMNKLGIHQNAT
KIRPPMPFSRENADLMLSTLDDVLGGL
>Mature_426_residues
SGNQEMIARRERLLGRNMSLFYQDPVHLVKGEGVWLWDADGRKYLDCYNNVPHVGHCHPRVVEAICRQASTLNTHTRYLH
EGILDYVERLTATFDKSLDAAILTCTGSEANDVALHMAQAVTGKTGIIATDFTYHGNTTAVSQLSTRMPPVGGYGGHVRH
VPAPDSYRPLGGKGGEAFAQAWAAEVEKAIASLQESPFGFSGLIIDPFFANEGFPDLPENFLAPAVAAVRKAGGVVIADE
VQPGFGRTGGHMWGHQKAGIVPDIVTLGKPMGNGHPVGAVVAGADTLNAFRKAFRYFNTFGGNPVSCAAAMAVLDVLEEE
KLQANALEVGAYARQGLEKLAQKHGMIGNVRGSGLFFGAELVLDRAEKTPAAEMATRVVNEMRERGVLMNKLGIHQNATK
IRPPMPFSRENADLMLSTLDDVLGGL

Specific function: The dialkylglycine decarboxylase is of interest because it normally catalyzes both decarboxylation and amino transfer. It may be more properly described as a decarboxylating aminotransferase rather than an aminotransferring decarboxylase [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=436, Percent_Identity=41.5137614678899, Blast_Score=343, Evalue=1e-94,
Organism=Homo sapiens, GI24119277, Length=433, Percent_Identity=41.5704387990762, Blast_Score=333, Evalue=1e-91,
Organism=Homo sapiens, GI226442705, Length=436, Percent_Identity=40.1376146788991, Blast_Score=322, Evalue=5e-88,
Organism=Homo sapiens, GI226442709, Length=381, Percent_Identity=43.0446194225722, Blast_Score=301, Evalue=6e-82,
Organism=Homo sapiens, GI13994255, Length=430, Percent_Identity=33.7209302325581, Blast_Score=235, Evalue=7e-62,
Organism=Homo sapiens, GI4557809, Length=413, Percent_Identity=28.3292978208232, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI188536080, Length=441, Percent_Identity=23.8095238095238, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI38679950, Length=441, Percent_Identity=23.8095238095238, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI38679946, Length=441, Percent_Identity=23.8095238095238, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI284507298, Length=190, Percent_Identity=32.1052631578947, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789016, Length=445, Percent_Identity=29.438202247191, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI145693181, Length=407, Percent_Identity=27.2727272727273, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1787560, Length=439, Percent_Identity=27.5626423690205, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788044, Length=412, Percent_Identity=26.9417475728155, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789759, Length=350, Percent_Identity=27.7142857142857, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786349, Length=350, Percent_Identity=27.1428571428571, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786991, Length=356, Percent_Identity=28.3707865168539, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71992977, Length=443, Percent_Identity=34.9887133182844, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI32564660, Length=431, Percent_Identity=34.338747099768, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI25144271, Length=438, Percent_Identity=27.3972602739726, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71992985, Length=144, Percent_Identity=34.7222222222222, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25144274, Length=197, Percent_Identity=30.9644670050761, Blast_Score=93, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17541228, Length=448, Percent_Identity=22.9910714285714, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71981843, Length=99, Percent_Identity=38.3838383838384, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6323470, Length=415, Percent_Identity=28.433734939759, Blast_Score=144, Evalue=4e-35,
Organism=Saccharomyces cerevisiae, GI6324432, Length=382, Percent_Identity=28.0104712041885, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6321456, Length=433, Percent_Identity=23.094688221709, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21356575, Length=435, Percent_Identity=41.3793103448276, Blast_Score=314, Evalue=6e-86,
Organism=Drosophila melanogaster, GI161085790, Length=446, Percent_Identity=35.6502242152466, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI28574759, Length=442, Percent_Identity=35.7466063348416, Blast_Score=265, Evalue=3e-71,
Organism=Drosophila melanogaster, GI21357415, Length=429, Percent_Identity=28.9044289044289, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281366494, Length=450, Percent_Identity=23.5555555555556, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24667139, Length=450, Percent_Identity=23.5555555555556, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24667143, Length=450, Percent_Identity=23.5555555555556, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =4.1.1.64 [H]

Molecular weight: Translated: 45930; Mature: 45799

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNQEMIARRERLLGRNMSLFYQDPVHLVKGEGVWLWDADGRKYLDCYNNVPHVGHCHP
CCCCHHHHHHHHHHHCCCCCEEEECCEEEEECCEEEEECCCCCHHHHHHCCCCCCCCCCH
RVVEAICRQASTLNTHTRYLHEGILDYVERLTATFDKSLDAAILTCTGSEANDVALHMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
AVTGKTGIIATDFTYHGNTTAVSQLSTRMPPVGGYGGHVRHVPAPDSYRPLGGKGGEAFA
HHCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHH
QAWAAEVEKAIASLQESPFGFSGLIIDPFFANEGFPDLPENFLAPAVAAVRKAGGVVIAD
HHHHHHHHHHHHHHHCCCCCCCCEEECHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEC
EVQPGFGRTGGHMWGHQKAGIVPDIVTLGKPMGNGHPVGAVVAGADTLNAFRKAFRYFNT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHH
FGGNPVSCAAAMAVLDVLEEEKLQANALEVGAYARQGLEKLAQKHGMIGNVRGSGLFFGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEHH
ELVLDRAEKTPAAEMATRVVNEMRERGVLMNKLGIHQNATKIRPPMPFSRENADLMLSTL
HHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
DDVLGGL
HHHHCCC
>Mature Secondary Structure 
SGNQEMIARRERLLGRNMSLFYQDPVHLVKGEGVWLWDADGRKYLDCYNNVPHVGHCHP
CCCHHHHHHHHHHHCCCCCEEEECCEEEEECCEEEEECCCCCHHHHHHCCCCCCCCCCH
RVVEAICRQASTLNTHTRYLHEGILDYVERLTATFDKSLDAAILTCTGSEANDVALHMAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
AVTGKTGIIATDFTYHGNTTAVSQLSTRMPPVGGYGGHVRHVPAPDSYRPLGGKGGEAFA
HHCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHH
QAWAAEVEKAIASLQESPFGFSGLIIDPFFANEGFPDLPENFLAPAVAAVRKAGGVVIAD
HHHHHHHHHHHHHHHCCCCCCCCEEECHHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEC
EVQPGFGRTGGHMWGHQKAGIVPDIVTLGKPMGNGHPVGAVVAGADTLNAFRKAFRYFNT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHH
FGGNPVSCAAAMAVLDVLEEEKLQANALEVGAYARQGLEKLAQKHGMIGNVRGSGLFFGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEHH
ELVLDRAEKTPAAEMATRVVNEMRERGVLMNKLGIHQNATKIRPPMPFSRENADLMLSTL
HHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
DDVLGGL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2180928; 8342040; 7947767; 7799433; 10556038 [H]