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The map label for this gene is dld [H]

Identifier: 225686826

GI number: 225686826

Start: 1035559

End: 1036077

Strand: Direct

Name: dld [H]

Synonym: BMEA_B1063

Alternate gene names: 225686826

Gene position: 1035559-1036077 (Clockwise)

Preceding gene: 225686820

Following gene: 225686827

Centisome position: 87.35

GC content: 51.25

Gene sequence:

>519_bases
ATGACGCGCGCCGCTATCTGGCCGAACGCTTTCCAACCACACATGGAAATTATTTCGAGTGCACCGACAAAGAAGGCAAG
GCGGCTTTCCTCAATCGGTTTGCTGTCGGTGGTTCGGTATCGTGCGGTTCATGCAAAGACAGTGGAAGATATTGTAGCAC
TCGATATCGCCTTGCCACGCAACACACTCGACTGGTTCGAACGTCTGCCTGCCGAAATCGAAAAGAAAATCGATGTCACC
ATGTATTGCGGGCACTTCTTCTGCCACGTTCTGCATCAGGAATATCTGGTCAAGAAAGGGGAGGACTGCGAGGCTTTGAA
GAAGGCAATTCTTGCCCTGCTGGAGGAACGCGGAGCGAAATATCCCGCCGAACATAATGTCGGGCATCTCTATGAGGCCG
AGGAAAGCCTCAAGAAGTTTTATCGGGACCTGGACCCTACCAACGCCTTCAATCCAGGGCTCGGTCAAACAAGCTATCTA
TTGAACTGGCAAACTCCAGGATATCATTCCGACCAATAG

Upstream 100 bases:

>100_bases
GTAACCGGTCTGTTGCCGGATCATCTGCCAACCAGGCTCAACAGTTTCCGAGATGGTTACGAACATCATCTGCTTTTGAA
AATGGGAAACGAGGGTATCG

Downstream 100 bases:

>100_bases
CAGCATCATTATGGAGCATGTTTACACGATAGGATTCGGCTTTCCTTTCTTGAAACGTAGTATTTCAAATAGTTGTGGCG
CTAAATCGATTACGACGGGG

Product: D-lactate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MTRAAIWPNAFQPHMEIISSAPTKKARRLSSIGLLSVVRYRAVHAKTVEDIVALDIALPRNTLDWFERLPAEIEKKIDVT
MYCGHFFCHVLHQEYLVKKGEDCEALKKAILALLEERGAKYPAEHNVGHLYEAEESLKKFYRDLDPTNAFNPGLGQTSYL
LNWQTPGYHSDQ

Sequences:

>Translated_172_residues
MTRAAIWPNAFQPHMEIISSAPTKKARRLSSIGLLSVVRYRAVHAKTVEDIVALDIALPRNTLDWFERLPAEIEKKIDVT
MYCGHFFCHVLHQEYLVKKGEDCEALKKAILALLEERGAKYPAEHNVGHLYEAEESLKKFYRDLDPTNAFNPGLGQTSYL
LNWQTPGYHSDQ
>Mature_171_residues
TRAAIWPNAFQPHMEIISSAPTKKARRLSSIGLLSVVRYRAVHAKTVEDIVALDIALPRNTLDWFERLPAEIEKKIDVTM
YCGHFFCHVLHQEYLVKKGEDCEALKKAILALLEERGAKYPAEHNVGHLYEAEESLKKFYRDLDPTNAFNPGLGQTSYLL
NWQTPGYHSDQ

Specific function: First component of the membrane-bound D-lactate oxidase, which is believed to play an important role in the energization of the active transport of a variety of sugars and amino acids [H]

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788454, Length=137, Percent_Identity=57.6642335766423, Blast_Score=174, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016172
- InterPro:   IPR016173
- InterPro:   IPR012256
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR015409
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF09330 Lact-deh-memb [H]

EC number: =1.1.1.28 [H]

Molecular weight: Translated: 19668; Mature: 19537

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAAIWPNAFQPHMEIISSAPTKKARRLSSIGLLSVVRYRAVHAKTVEDIVALDIALPR
CCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NTLDWFERLPAEIEKKIDVTMYCGHFFCHVLHQEYLVKKGEDCEALKKAILALLEERGAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
YPAEHNVGHLYEAEESLKKFYRDLDPTNAFNPGLGQTSYLLNWQTPGYHSDQ
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TRAAIWPNAFQPHMEIISSAPTKKARRLSSIGLLSVVRYRAVHAKTVEDIVALDIALPR
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
NTLDWFERLPAEIEKKIDVTMYCGHFFCHVLHQEYLVKKGEDCEALKKAILALLEERGAK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
YPAEHNVGHLYEAEESLKKFYRDLDPTNAFNPGLGQTSYLLNWQTPGYHSDQ
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]