Click here to switch to the map view.

The map label for this gene is dapB [H]

Identifier: 225686805

GI number: 225686805

Start: 1014604

End: 1015443

Strand: Direct

Name: dapB [H]

Synonym: BMEA_B1036

Alternate gene names: 225686805

Gene position: 1014604-1015443 (Clockwise)

Preceding gene: 225686804

Following gene: 225686806

Centisome position: 85.58

GC content: 62.98

Gene sequence:

>840_bases
ATGAGCGGGGAAGTGCAAGGCGGCAACAGCGAAATGGGCCTGGTTGTGGTTGGCGCGGGCGGCCGCATGGGCCAAACGCT
CATCCGCACCATCCAGTCGATCGAAGGCGCCAAACTGGTTGGTGCAATCGAGCGTTCCGGTTCCCCGTTTCTCGGCAAGG
ATGCTGGCGAAGTGACCGGCATCGGCACGCTTGGCGTGGCGATTACCGACGATCCGCTGCCAGTCTTCGCCAAGGCGCAC
GGTGTCCTTGATTTCACCAGCCCTGCCGCAAGTGTGGAATTTGCCGGGCTTGCGGCGCAGGCCCGCATCGTTCATGTGAT
CGGCACCACTGGCTGTTCGGCAGAGGATGATGAGAAAATCCGCGCCGCCGCCCGCCACGCCACCATCGTCAAGTCCGGCA
ATATGAGCCTCGGCGTCAATCTCCTCTCCGTGCTCGTGCAGAAGGCGGCAGAGGCTCTTGGGCCGGAAGATTTCGACATA
GAAATTCTGGAAATGCACCACAGGCACAAGGTTGATGCGCCATCCGGCACGGCGCTGCTGCTTGGTGAAGCGGCAGCGCG
CGGACGCGACATTGCGCTGGCGGATAACAGCGTGCGCGTGCGTGATGGCTATACTGGCCCGCGCGAAACCGGCGCCATCG
GCTTTGCCACGCTGCGCGGCGGTTCCGTCATTGGCGACCATTCGGTGATTCTGGCAGACACGGGCGAGCGTGTCGTACTT
TCTCACCACGCCGAAGACCGCTCGATCTTCGCACGCGGCGCGATCAAGGCTGCGCTTTGGGCCCACGGCAAGAAGCCGGG
CCTCTATTCCATGCTCGACGTGCTCGGGCTCAATACGTGA

Upstream 100 bases:

>100_bases
TCGAGAACGGTGTCTATGCCCGTTTCTATCAGTTGCAGCGCGGCAAGGACGACATCATCACCGAACAATCGGAAGAAGCA
CTGCACACAGGAGAGGCCAG

Downstream 100 bases:

>100_bases
TAAATGACTGATTCTTCCCACCAACGGAGTACTGCGATGTCTCGTACCCTCGTCCTGGTCCGCCATGGCCAAAGCGAATG
GAACCTCAAGAACCTCTTTA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSGEVQGGNSEMGLVVVGAGGRMGQTLIRTIQSIEGAKLVGAIERSGSPFLGKDAGEVTGIGTLGVAITDDPLPVFAKAH
GVLDFTSPAASVEFAGLAAQARIVHVIGTTGCSAEDDEKIRAAARHATIVKSGNMSLGVNLLSVLVQKAAEALGPEDFDI
EILEMHHRHKVDAPSGTALLLGEAAARGRDIALADNSVRVRDGYTGPRETGAIGFATLRGGSVIGDHSVILADTGERVVL
SHHAEDRSIFARGAIKAALWAHGKKPGLYSMLDVLGLNT

Sequences:

>Translated_279_residues
MSGEVQGGNSEMGLVVVGAGGRMGQTLIRTIQSIEGAKLVGAIERSGSPFLGKDAGEVTGIGTLGVAITDDPLPVFAKAH
GVLDFTSPAASVEFAGLAAQARIVHVIGTTGCSAEDDEKIRAAARHATIVKSGNMSLGVNLLSVLVQKAAEALGPEDFDI
EILEMHHRHKVDAPSGTALLLGEAAARGRDIALADNSVRVRDGYTGPRETGAIGFATLRGGSVIGDHSVILADTGERVVL
SHHAEDRSIFARGAIKAALWAHGKKPGLYSMLDVLGLNT
>Mature_278_residues
SGEVQGGNSEMGLVVVGAGGRMGQTLIRTIQSIEGAKLVGAIERSGSPFLGKDAGEVTGIGTLGVAITDDPLPVFAKAHG
VLDFTSPAASVEFAGLAAQARIVHVIGTTGCSAEDDEKIRAAARHATIVKSGNMSLGVNLLSVLVQKAAEALGPEDFDIE
ILEMHHRHKVDAPSGTALLLGEAAARGRDIALADNSVRVRDGYTGPRETGAIGFATLRGGSVIGDHSVILADTGERVVLS
HHAEDRSIFARGAIKAALWAHGKKPGLYSMLDVLGLNT

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=272, Percent_Identity=45.2205882352941, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28739; Mature: 28608

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEVQGGNSEMGLVVVGAGGRMGQTLIRTIQSIEGAKLVGAIERSGSPFLGKDAGEVTG
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCCCCCCEEE
IGTLGVAITDDPLPVFAKAHGVLDFTSPAASVEFAGLAAQARIVHVIGTTGCSAEDDEKI
EEEEEEEEECCCCCEEEHHCCEEEECCCCCCEEECCEEECEEEEEEEECCCCCCCCHHHH
RAAARHATIVKSGNMSLGVNLLSVLVQKAAEALGPEDFDIEILEMHHRHKVDAPSGTALL
HHHHHHEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCCCCCCCCEEE
LGEAAARGRDIALADNSVRVRDGYTGPRETGAIGFATLRGGSVIGDHSVILADTGERVVL
EECCCCCCCEEEEECCCEEEECCCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEE
SHHAEDRSIFARGAIKAALWAHGKKPGLYSMLDVLGLNT
EECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
SGEVQGGNSEMGLVVVGAGGRMGQTLIRTIQSIEGAKLVGAIERSGSPFLGKDAGEVTG
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCCCCCCEEE
IGTLGVAITDDPLPVFAKAHGVLDFTSPAASVEFAGLAAQARIVHVIGTTGCSAEDDEKI
EEEEEEEEECCCCCEEEHHCCEEEECCCCCCEEECCEEECEEEEEEEECCCCCCCCHHHH
RAAARHATIVKSGNMSLGVNLLSVLVQKAAEALGPEDFDIEILEMHHRHKVDAPSGTALL
HHHHHHEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCCCCCCCCEEE
LGEAAARGRDIALADNSVRVRDGYTGPRETGAIGFATLRGGSVIGDHSVILADTGERVVL
EECCCCCCCEEEEECCCEEEECCCCCCCCCCCEEEEEECCCCEECCCEEEEECCCCEEEE
SHHAEDRSIFARGAIKAALWAHGKKPGLYSMLDVLGLNT
EECCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA