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The map label for this gene is fmt [H]

Identifier: 225686788

GI number: 225686788

Start: 999088

End: 1000008

Strand: Reverse

Name: fmt [H]

Synonym: BMEA_B1019

Alternate gene names: 225686788

Gene position: 1000008-999088 (Counterclockwise)

Preceding gene: 225686789

Following gene: 225686787

Centisome position: 84.35

GC content: 61.45

Gene sequence:

>921_bases
ATGCGTGTTGTTTTCATGGGGACGCCGGAATTTTCCGTGCCGATCCTCACCGCCATCATCGGTCACGGTTATGAGGTCGT
TGCAGCCTATACGCAGCCGCCGCGCCCGGCAGGCCGCAGAGGTCTGGAACTCACCAGATCGCCGGTGCATGAAAAAGCAG
AGCAATTCGGCATTCCGGTTTTCACGCCGAAGAGCCTCAAGGGCGCGGAAGAGCAGGATGTTTTCGCAAGCCTTAAAGCC
GATGTGGCGATTGTCGTGGCCTATGGGCTTTTGCTGCCGAAGGCCATTCTCGATGCGCCGCGGCTTGGCTGCTATAACGG
CCATGCGTCGCTTTTGCCGCGTTGGCGCGGTGCAGCGCCCATCCAGCGCGCTATTATGGCAGGCGATGCGGAAACCGGCA
TGATGATCATGAAGATGGATGAGGGGCTTGATACCGGGCCTGTCGCCATGGCCGAAAAGGTGGCCATCACGCCGGATATG
ACGGCGGGCGAACTGCATGATCGCCTGAGCATGATTGGCGCTGACCTGATGATCCGCGCGCTGGGCGCGCTTGAGCGCGA
AAGCCTTGCCTTGCAGCCGCAGGCGGAAGAAGGCGTTACTTATGCCGCAAAGATCGACAAGGCGGAGGCCCGCATCGACT
GGTCGAAGCCTGCAAAAGACGTGCACAATAGCATTCGCGGCCTGTCACCCTTTCCGGGCGCGTGGTGCGAGATGGAAATC
AACGGTGCTGTCGAGCGCGTGAAGTTGCAGCGTTCCACGCTGGGCGAAGGTTCGGGCGCGCCGGGCACGGTGCTGGATGA
TCGCCTGACGATTGCCTGCGGCGAGGGCGCGGTGCGGCTTGCCACGCTGCAACGTTCCGGCGGAAAACCCTTGCCTGCAC
AAGAGTTTCTGCGTGGGCAGCGCGTCACGAAGGTTCTCTAG

Upstream 100 bases:

>100_bases
GTGTGCTCTTCATCGACCATATTTCCAAGCTGAAGCGCGATATGGTCATCAAGAAGTTCAAGAAGCTCGCCAGCCAGCGG
GCATCGAAGAAAGTGCTTTA

Downstream 100 bases:

>100_bases
CCTGTGCCGCGCTACAAGCTCACGGTTGAATATGACGGCACGCCCTATGTCGGCTGGCAGCGACAGGAAAACGGCCATGC
GGTGCAAGGCGCTATTGAGC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MRVVFMGTPEFSVPILTAIIGHGYEVVAAYTQPPRPAGRRGLELTRSPVHEKAEQFGIPVFTPKSLKGAEEQDVFASLKA
DVAIVVAYGLLLPKAILDAPRLGCYNGHASLLPRWRGAAPIQRAIMAGDAETGMMIMKMDEGLDTGPVAMAEKVAITPDM
TAGELHDRLSMIGADLMIRALGALERESLALQPQAEEGVTYAAKIDKAEARIDWSKPAKDVHNSIRGLSPFPGAWCEMEI
NGAVERVKLQRSTLGEGSGAPGTVLDDRLTIACGEGAVRLATLQRSGGKPLPAQEFLRGQRVTKVL

Sequences:

>Translated_306_residues
MRVVFMGTPEFSVPILTAIIGHGYEVVAAYTQPPRPAGRRGLELTRSPVHEKAEQFGIPVFTPKSLKGAEEQDVFASLKA
DVAIVVAYGLLLPKAILDAPRLGCYNGHASLLPRWRGAAPIQRAIMAGDAETGMMIMKMDEGLDTGPVAMAEKVAITPDM
TAGELHDRLSMIGADLMIRALGALERESLALQPQAEEGVTYAAKIDKAEARIDWSKPAKDVHNSIRGLSPFPGAWCEMEI
NGAVERVKLQRSTLGEGSGAPGTVLDDRLTIACGEGAVRLATLQRSGGKPLPAQEFLRGQRVTKVL
>Mature_306_residues
MRVVFMGTPEFSVPILTAIIGHGYEVVAAYTQPPRPAGRRGLELTRSPVHEKAEQFGIPVFTPKSLKGAEEQDVFASLKA
DVAIVVAYGLLLPKAILDAPRLGCYNGHASLLPRWRGAAPIQRAIMAGDAETGMMIMKMDEGLDTGPVAMAEKVAITPDM
TAGELHDRLSMIGADLMIRALGALERESLALQPQAEEGVTYAAKIDKAEARIDWSKPAKDVHNSIRGLSPFPGAWCEMEI
NGAVERVKLQRSTLGEGSGAPGTVLDDRLTIACGEGAVRLATLQRSGGKPLPAQEFLRGQRVTKVL

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=319, Percent_Identity=29.4670846394984, Blast_Score=128, Evalue=6e-30,
Organism=Homo sapiens, GI238814322, Length=316, Percent_Identity=30.379746835443, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI164663775, Length=325, Percent_Identity=30.4615384615385, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1789683, Length=306, Percent_Identity=46.078431372549, Blast_Score=260, Evalue=8e-71,
Organism=Escherichia coli, GI1788589, Length=290, Percent_Identity=28.6206896551724, Blast_Score=117, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI133930964, Length=333, Percent_Identity=28.2282282282282, Blast_Score=103, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6319458, Length=277, Percent_Identity=27.7978339350181, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45550868, Length=315, Percent_Identity=30.7936507936508, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28571984, Length=229, Percent_Identity=34.4978165938865, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24585660, Length=261, Percent_Identity=26.0536398467433, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 32771; Mature: 32771

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVFMGTPEFSVPILTAIIGHGYEVVAAYTQPPRPAGRRGLELTRSPVHEKAEQFGIPV
CEEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
FTPKSLKGAEEQDVFASLKADVAIVVAYGLLLPKAILDAPRLGCYNGHASLLPRWRGAAP
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCH
IQRAIMAGDAETGMMIMKMDEGLDTGPVAMAEKVAITPDMTAGELHDRLSMIGADLMIRA
HHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGALERESLALQPQAEEGVTYAAKIDKAEARIDWSKPAKDVHNSIRGLSPFPGAWCEMEI
HHHHHHHHEECCCCHHHCCEEEEEECHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEEE
NGAVERVKLQRSTLGEGSGAPGTVLDDRLTIACGEGAVRLATLQRSGGKPLPAQEFLRGQ
CCHHHHHHHHHHHCCCCCCCCCCEECCCEEEEECCCCEEEEEEECCCCCCCCHHHHHCHH
RVTKVL
HHHHCC
>Mature Secondary Structure
MRVVFMGTPEFSVPILTAIIGHGYEVVAAYTQPPRPAGRRGLELTRSPVHEKAEQFGIPV
CEEEEECCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
FTPKSLKGAEEQDVFASLKADVAIVVAYGLLLPKAILDAPRLGCYNGHASLLPRWRGAAP
CCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCH
IQRAIMAGDAETGMMIMKMDEGLDTGPVAMAEKVAITPDMTAGELHDRLSMIGADLMIRA
HHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHH
LGALERESLALQPQAEEGVTYAAKIDKAEARIDWSKPAKDVHNSIRGLSPFPGAWCEMEI
HHHHHHHHEECCCCHHHCCEEEEEECHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEEEEE
NGAVERVKLQRSTLGEGSGAPGTVLDDRLTIACGEGAVRLATLQRSGGKPLPAQEFLRGQ
CCHHHHHHHHHHHCCCCCCCCCCEECCCEEEEECCCCEEEEEEECCCCCCCCHHHHHCHH
RVTKVL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA