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The map label for this gene is yebQ [H]

Identifier: 225686772

GI number: 225686772

Start: 984692

End: 986071

Strand: Direct

Name: yebQ [H]

Synonym: BMEA_B1002

Alternate gene names: 225686772

Gene position: 984692-986071 (Clockwise)

Preceding gene: 225686761

Following gene: 225686773

Centisome position: 83.06

GC content: 57.9

Gene sequence:

>1380_bases
ATGAAACACAAAACCGCTATCCAACAAGGCGTGTCCCTTGCCCCGGATGGATTGCCCAGGCCGCGCATTTATTGGGCCTG
GGCCACGTTGATGGTCGGCCTTACCCTGGCCGTGATTGACGGCACCATTGCCAATGTCGCGCTTCCCACCATTGCTGCCG
ATTTCTCCGCAGGACCGGCCGCGTCGATCTGGATCGTCAACGGCTATCAGCTTGCTATTGTCATCACCATGCTGCCGCTT
GCCGCGCTTGGCGAAATCTACGGCTATCGCCGTGTTTATGTCGCAGGCGTGGCCCTCTTCACCATTGCGTCCATCGGCTG
CGTGTTCTCCCGTTCCCTTGAGGCGCTAACACTCGCCCGCATTATTCAGGGGCTGGGTGCAGCCGGCCTGATGAGCGTCA
ATACGGCACTCCTGCGCTACACGGTTCCACAAGCCAAATTCGGCACGGCCATCGGCCTCAATGCCCTTTTTGTCGCCGTT
TCCTCCACCATCGGCCCCTCGCTTGCCGGTGTCATGCTGTCTTCGCTCAGTTGGCCCTGGCTCTTTGTAATCAATATTCC
GCTTGGTATCGCCGCCGTTCTCATGGGGCTGCGAAGCTTGCCCGATAATGACCGCTCAGCACGCAAGTTCGATGTGGTCA
GCGCCATTCTGTGCGCCGTCACCTTTGGCCTGCTGATTACGACTATCGACAGCGCAGGCAATAAAATCGGCTCCCTTGCC
GTGATGTTGCAGGCGCTCTGCTGCCTGCTGGCAGGCATATGGCTGACGCGGCGATCATTTCACATGAGCGATCCCCTGCT
GCCGCTCGATCTTTTGCGGATACCCGTGTTCACGCTGTCCATCTGCACCTCGATCATGTCGTTCCTGGCGCAGATGATGG
CTTTTATTTCTCTGCCCTTCCTGTTCCAGACCGTGTTCGGCTTTCGGCCAATTGAAGTGGGCTTCCTGATGATGCCTTGG
CCGATTGCGCTGGCGCTTGTCGCCCCTCTTTCGGGCAAACTTTCTGACAAATACTCTCCGGCAATTCTTGGCCTGCTCGG
CCTCATCACTTTTTCTGTTGGATTGGCGCTTGTCGGCCTGCTTCCTGGGCATCCGACGATTCCCGACATCTGCTGGCGCA
TGGCAATTTGCGGTATCGGATTCGGTCTTTTTCAAGCGCCCAACAACCGCATGATGATAACCTCGACACCACGCGCCCGC
AGCGGCGCGGCAAGCGGAATGCTCGGCACAGCACGCCTGTTGGGCCAATCTGTTGGCGCAGCGCTCGTGGCTTTTCTGCT
TTCACAATGGGGGGTAGAAGGCACGCCTTACATTCTCTTCCTTGCATCAGGCTTTGCCCTCTTCGCATCAGTCATCAGCA
TCTCACGCCTCAGGCACTGA

Upstream 100 bases:

>100_bases
TAAGCTAGATGATCTAGAAACCCTCCCAATCCGGATAAGGTTACAAAAATCCCGTTATTTTTAGCGTACCGGATCACCGG
TCGCATCATTGGCTGATGGA

Downstream 100 bases:

>100_bases
CAGCGAATACCGGACGCTTTCCAACGCTCATCCACAGGTTTGAAAACACCATGCAAATATCTTGTGTCGGGATGTTATTT
TCCCTGTTGCAATCTGCGGA

Product: drug resistance transporter, EmrB/QacA subfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKHKTAIQQGVSLAPDGLPRPRIYWAWATLMVGLTLAVIDGTIANVALPTIAADFSAGPAASIWIVNGYQLAIVITMLPL
AALGEIYGYRRVYVAGVALFTIASIGCVFSRSLEALTLARIIQGLGAAGLMSVNTALLRYTVPQAKFGTAIGLNALFVAV
SSTIGPSLAGVMLSSLSWPWLFVINIPLGIAAVLMGLRSLPDNDRSARKFDVVSAILCAVTFGLLITTIDSAGNKIGSLA
VMLQALCCLLAGIWLTRRSFHMSDPLLPLDLLRIPVFTLSICTSIMSFLAQMMAFISLPFLFQTVFGFRPIEVGFLMMPW
PIALALVAPLSGKLSDKYSPAILGLLGLITFSVGLALVGLLPGHPTIPDICWRMAICGIGFGLFQAPNNRMMITSTPRAR
SGAASGMLGTARLLGQSVGAALVAFLLSQWGVEGTPYILFLASGFALFASVISISRLRH

Sequences:

>Translated_459_residues
MKHKTAIQQGVSLAPDGLPRPRIYWAWATLMVGLTLAVIDGTIANVALPTIAADFSAGPAASIWIVNGYQLAIVITMLPL
AALGEIYGYRRVYVAGVALFTIASIGCVFSRSLEALTLARIIQGLGAAGLMSVNTALLRYTVPQAKFGTAIGLNALFVAV
SSTIGPSLAGVMLSSLSWPWLFVINIPLGIAAVLMGLRSLPDNDRSARKFDVVSAILCAVTFGLLITTIDSAGNKIGSLA
VMLQALCCLLAGIWLTRRSFHMSDPLLPLDLLRIPVFTLSICTSIMSFLAQMMAFISLPFLFQTVFGFRPIEVGFLMMPW
PIALALVAPLSGKLSDKYSPAILGLLGLITFSVGLALVGLLPGHPTIPDICWRMAICGIGFGLFQAPNNRMMITSTPRAR
SGAASGMLGTARLLGQSVGAALVAFLLSQWGVEGTPYILFLASGFALFASVISISRLRH
>Mature_459_residues
MKHKTAIQQGVSLAPDGLPRPRIYWAWATLMVGLTLAVIDGTIANVALPTIAADFSAGPAASIWIVNGYQLAIVITMLPL
AALGEIYGYRRVYVAGVALFTIASIGCVFSRSLEALTLARIIQGLGAAGLMSVNTALLRYTVPQAKFGTAIGLNALFVAV
SSTIGPSLAGVMLSSLSWPWLFVINIPLGIAAVLMGLRSLPDNDRSARKFDVVSAILCAVTFGLLITTIDSAGNKIGSLA
VMLQALCCLLAGIWLTRRSFHMSDPLLPLDLLRIPVFTLSICTSIMSFLAQMMAFISLPFLFQTVFGFRPIEVGFLMMPW
PIALALVAPLSGKLSDKYSPAILGLLGLITFSVGLALVGLLPGHPTIPDICWRMAICGIGFGLFQAPNNRMMITSTPRAR
SGAASGMLGTARLLGQSVGAALVAFLLSQWGVEGTPYILFLASGFALFASVISISRLRH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=422, Percent_Identity=52.8436018957346, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1790195, Length=414, Percent_Identity=27.7777777777778, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI1789042, Length=397, Percent_Identity=26.9521410579345, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1788710, Length=402, Percent_Identity=25.6218905472637, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788392, Length=297, Percent_Identity=28.2828282828283, Blast_Score=106, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325455, Length=387, Percent_Identity=25.8397932816537, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321663, Length=179, Percent_Identity=26.2569832402235, Blast_Score=67, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322958, Length=197, Percent_Identity=23.8578680203046, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48601; Mature: 48601

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHKTAIQQGVSLAPDGLPRPRIYWAWATLMVGLTLAVIDGTIANVALPTIAADFSAGPA
CCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
ASIWIVNGYQLAIVITMLPLAALGEIYGYRRVYVAGVALFTIASIGCVFSRSLEALTLAR
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIQGLGAAGLMSVNTALLRYTVPQAKFGTAIGLNALFVAVSSTIGPSLAGVMLSSLSWPW
HHHHCCCHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCE
LFVINIPLGIAAVLMGLRSLPDNDRSARKFDVVSAILCAVTFGLLITTIDSAGNKIGSLA
EEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VMLQALCCLLAGIWLTRRSFHMSDPLLPLDLLRIPVFTLSICTSIMSFLAQMMAFISLPF
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFQTVFGFRPIEVGFLMMPWPIALALVAPLSGKLSDKYSPAILGLLGLITFSVGLALVGL
HHHHHHCCCCHHCCEEECCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LPGHPTIPDICWRMAICGIGFGLFQAPNNRMMITSTPRARSGAASGMLGTARLLGQSVGA
CCCCCCHHHHHHHHHHHHHCHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
ALVAFLLSQWGVEGTPYILFLASGFALFASVISISRLRH
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHKTAIQQGVSLAPDGLPRPRIYWAWATLMVGLTLAVIDGTIANVALPTIAADFSAGPA
CCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
ASIWIVNGYQLAIVITMLPLAALGEIYGYRRVYVAGVALFTIASIGCVFSRSLEALTLAR
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIQGLGAAGLMSVNTALLRYTVPQAKFGTAIGLNALFVAVSSTIGPSLAGVMLSSLSWPW
HHHHCCCHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCE
LFVINIPLGIAAVLMGLRSLPDNDRSARKFDVVSAILCAVTFGLLITTIDSAGNKIGSLA
EEEEECHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VMLQALCCLLAGIWLTRRSFHMSDPLLPLDLLRIPVFTLSICTSIMSFLAQMMAFISLPF
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFQTVFGFRPIEVGFLMMPWPIALALVAPLSGKLSDKYSPAILGLLGLITFSVGLALVGL
HHHHHHCCCCHHCCEEECCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LPGHPTIPDICWRMAICGIGFGLFQAPNNRMMITSTPRARSGAASGMLGTARLLGQSVGA
CCCCCCHHHHHHHHHHHHHCHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHH
ALVAFLLSQWGVEGTPYILFLASGFALFASVISISRLRH
HHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]