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The map label for this gene is 225686757

Identifier: 225686757

GI number: 225686757

Start: 968169

End: 968555

Strand: Reverse

Name: 225686757

Synonym: BMEA_B0986

Alternate gene names: NA

Gene position: 968555-968169 (Counterclockwise)

Preceding gene: 225686758

Following gene: 225686756

Centisome position: 81.7

GC content: 52.97

Gene sequence:

>387_bases
TTGCAGATCAGCCGCATCGACCATTTTGTGCTCACTGTTCAGGATATTGACGTAACCTGCGATTTCTATAGCAGGGCCTG
CGGTATGGAAGTCGTGACTTTTGCCGGAGGGCGAAAGGCGCTTTCCTTTGGCCAGCATAAAATCAATCTCCATCAGGCGG
GGTCTGAATTCCTGCCCAAAGCCGCCAGCCCCACCCGTGGTAGCGGGGATTTCTGCCTCATCAGTTCCATACCGCTGGAC
GAGGTTATCGCGCATTTGGAAACTGAAAATATTGCGATTGAAGACGGGCCTGTGGCGCGCACAGGTGCGATGGGGCCAAT
CCGCTCCATCTATTTTCGTGATCCCGACGGAAACCTCGTGGAAATTTCAGAATATATCGACCTGTAG

Upstream 100 bases:

>100_bases
CGCGGGAACCGCTCGCTCTCTTTGCTTTTACGTATTATCCTGCGCAAAGCCGCTTTGCCTTTTCGGCTCGAAAACACTCG
AAGCAAGAAGGAGTTCCATC

Downstream 100 bases:

>100_bases
CTGCCGAACGGGGTGGCAAACGGGATATTTCCCGTGCGCTGTCATTATTTTTCATAGTCTGCCAGCCAATCTTTGCATCA
GCGCAACGATTGGTTTGGCG

Product: glyoxalase domain-containing protein 5

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MQISRIDHFVLTVQDIDVTCDFYSRACGMEVVTFAGGRKALSFGQHKINLHQAGSEFLPKAASPTRGSGDFCLISSIPLD
EVIAHLETENIAIEDGPVARTGAMGPIRSIYFRDPDGNLVEISEYIDL

Sequences:

>Translated_128_residues
MQISRIDHFVLTVQDIDVTCDFYSRACGMEVVTFAGGRKALSFGQHKINLHQAGSEFLPKAASPTRGSGDFCLISSIPLD
EVIAHLETENIAIEDGPVARTGAMGPIRSIYFRDPDGNLVEISEYIDL
>Mature_128_residues
MQISRIDHFVLTVQDIDVTCDFYSRACGMEVVTFAGGRKALSFGQHKINLHQAGSEFLPKAASPTRGSGDFCLISSIPLD
EVIAHLETENIAIEDGPVARTGAMGPIRSIYFRDPDGNLVEISEYIDL

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=124, Percent_Identity=59.6774193548387, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 13987; Mature: 13987

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISRIDHFVLTVQDIDVTCDFYSRACGMEVVTFAGGRKALSFGQHKINLHQAGSEFLPK
CCCCCCEEEEEEEEECEEEEEHHHCCCCCEEEEECCCCCEECCCCEEEEEECCCHHHCCC
AASPTRGSGDFCLISSIPLDEVIAHLETENIAIEDGPVARTGAMGPIRSIYFRDPDGNLV
CCCCCCCCCCEEEEECCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCEE
EISEYIDL
EECCCCCC
>Mature Secondary Structure
MQISRIDHFVLTVQDIDVTCDFYSRACGMEVVTFAGGRKALSFGQHKINLHQAGSEFLPK
CCCCCCEEEEEEEEECEEEEEHHHCCCCCEEEEECCCCCEECCCCEEEEEECCCHHHCCC
AASPTRGSGDFCLISSIPLDEVIAHLETENIAIEDGPVARTGAMGPIRSIYFRDPDGNLV
CCCCCCCCCCEEEEECCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCEE
EISEYIDL
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]