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The map label for this gene is nlpI [C]

Identifier: 225686724

GI number: 225686724

Start: 931618

End: 932505

Strand: Reverse

Name: nlpI [C]

Synonym: BMEA_B0950

Alternate gene names: 225686724

Gene position: 932505-931618 (Counterclockwise)

Preceding gene: 225686726

Following gene: 225686723

Centisome position: 78.66

GC content: 56.31

Gene sequence:

>888_bases
ATGCTGCAATTGGCGATGCGCTTAAAGGTGATGCAATTGTCTGAAACGGAGGTTTCGGGAATTGAGGCGTCGGGTGGAGC
AGGCCGAAACGGCCTTATCATCGCCGCCGCACTTCTGGCTTTGACCGTTGCCGGGTGCCAAAGTACCAATTCGACGCTCA
GCACTGTCGATAGGGCACAGGGATCGAGCGAGAATATCAGTTCGCTGACGAGCGTGATCCAGAGCAATCCGCGCGATCCC
GAAGGCTATAATGTTCGCGGCTCCGCTTATGGCAAGGCCGGACGCTACAAGGAAGCGATGCGCGATTTCGATCAGGCGAT
CGCGCTTAACCCGAATTTCTATCAGGCCTATGCCAACCGTGCGCTGGTCGATCGCTATATGGGTGACAACAATAAGGCCG
TGCAGGACTACAGCCGCGCTATCCAGCTTAATCCGCAATATGACGCCGCCTATATCGGCCGTGGCAATGTCTATCGTCAG
GCGGGTCATCTCGATCAGGCACTCAACGATTTCAACCAGGCCATTGCCTTGCGGACCACAGATGGCCGCGCCTATCACAA
TCGCGGGCTGATCTATCAGGCCAAGGGCCTGCATAAGCAGGCCATCGAGGACTTCTCGAAAGCAATTTCGCTCAATTCCA
CTGCGCCTGAACCCTATAACGGGCGCGGAATTTCCTATGTGGCGCTGGGTGATTACGATAACGCTTTCGACGATTTCAAC
ACGGCGATCACGCTCGACCAGAATGTGGCCGAAAGCTGGGCCAATCAGGCGCTGGTCTACGAACACAATGGCGACAAGGC
AAAGGCTGCAAATTCTTACGCCCGCGCCGTGCAGCTCGACCCGAAGTATAAGCCTGCGAAAGACGGTCTGGCCCGCACGC
GGGGTTAA

Upstream 100 bases:

>100_bases
CTGACAAATCGTCCAACGAGGCGTAAGGTCTGAAGATCCGGTGCGGAATGGAAAAGAAGCAGGGGCCCGTGGCCTTGCTG
TTTCTGTCGAGCTGAAAGGA

Downstream 100 bases:

>100_bases
GTTTGCGCATCTGCGATACGATCAAAGCGGCGATTCCCGAACCGGGGGAGCGCCGCTTTTCTTTATCGCAAACCGCGATA
TATTCAATTTCATGTCACTC

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLQLAMRLKVMQLSETEVSGIEASGGAGRNGLIIAAALLALTVAGCQSTNSTLSTVDRAQGSSENISSLTSVIQSNPRDP
EGYNVRGSAYGKAGRYKEAMRDFDQAIALNPNFYQAYANRALVDRYMGDNNKAVQDYSRAIQLNPQYDAAYIGRGNVYRQ
AGHLDQALNDFNQAIALRTTDGRAYHNRGLIYQAKGLHKQAIEDFSKAISLNSTAPEPYNGRGISYVALGDYDNAFDDFN
TAITLDQNVAESWANQALVYEHNGDKAKAANSYARAVQLDPKYKPAKDGLARTRG

Sequences:

>Translated_295_residues
MLQLAMRLKVMQLSETEVSGIEASGGAGRNGLIIAAALLALTVAGCQSTNSTLSTVDRAQGSSENISSLTSVIQSNPRDP
EGYNVRGSAYGKAGRYKEAMRDFDQAIALNPNFYQAYANRALVDRYMGDNNKAVQDYSRAIQLNPQYDAAYIGRGNVYRQ
AGHLDQALNDFNQAIALRTTDGRAYHNRGLIYQAKGLHKQAIEDFSKAISLNSTAPEPYNGRGISYVALGDYDNAFDDFN
TAITLDQNVAESWANQALVYEHNGDKAKAANSYARAVQLDPKYKPAKDGLARTRG
>Mature_295_residues
MLQLAMRLKVMQLSETEVSGIEASGGAGRNGLIIAAALLALTVAGCQSTNSTLSTVDRAQGSSENISSLTSVIQSNPRDP
EGYNVRGSAYGKAGRYKEAMRDFDQAIALNPNFYQAYANRALVDRYMGDNNKAVQDYSRAIQLNPQYDAAYIGRGNVYRQ
AGHLDQALNDFNQAIALRTTDGRAYHNRGLIYQAKGLHKQAIEDFSKAISLNSTAPEPYNGRGISYVALGDYDNAFDDFN
TAITLDQNVAESWANQALVYEHNGDKAKAANSYARAVQLDPKYKPAKDGLARTRG

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI170784867, Length=242, Percent_Identity=29.3388429752066, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI32307150, Length=222, Percent_Identity=30.6306306306306, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI32307148, Length=222, Percent_Identity=30.6306306306306, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI296531396, Length=190, Percent_Identity=29.4736842105263, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI310123097, Length=184, Percent_Identity=28.804347826087, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI310131789, Length=184, Percent_Identity=28.804347826087, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI310110582, Length=184, Percent_Identity=28.804347826087, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115532692, Length=219, Percent_Identity=28.7671232876712, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115532690, Length=219, Percent_Identity=28.7671232876712, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17647755, Length=216, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24585827, Length=216, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24585829, Length=216, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647123, Length=179, Percent_Identity=27.9329608938547, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21355911, Length=222, Percent_Identity=24.3243243243243, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 32108; Mature: 32108

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLAMRLKVMQLSETEVSGIEASGGAGRNGLIIAAALLALTVAGCQSTNSTLSTVDRAQ
CCCHHHHHHHHHHCCCHHCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GSSENISSLTSVIQSNPRDPEGYNVRGSAYGKAGRYKEAMRDFDQAIALNPNFYQAYANR
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHH
ALVDRYMGDNNKAVQDYSRAIQLNPQYDAAYIGRGNVYRQAGHLDQALNDFNQAIALRTT
HHHHHHHCCCCHHHHHHHHHEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEEEC
DGRAYHNRGLIYQAKGLHKQAIEDFSKAISLNSTAPEPYNGRGISYVALGDYDNAFDDFN
CCCEECCCCCEEECCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCHHCCC
TAITLDQNVAESWANQALVYEHNGDKAKAANSYARAVQLDPKYKPAKDGLARTRG
CEEEECHHHHHHHHCCEEEEEECCCCHHHHHHHHHEEECCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MLQLAMRLKVMQLSETEVSGIEASGGAGRNGLIIAAALLALTVAGCQSTNSTLSTVDRAQ
CCCHHHHHHHHHHCCCHHCCEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHC
GSSENISSLTSVIQSNPRDPEGYNVRGSAYGKAGRYKEAMRDFDQAIALNPNFYQAYANR
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCHHHHHHHHH
ALVDRYMGDNNKAVQDYSRAIQLNPQYDAAYIGRGNVYRQAGHLDQALNDFNQAIALRTT
HHHHHHHCCCCHHHHHHHHHEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEEEC
DGRAYHNRGLIYQAKGLHKQAIEDFSKAISLNSTAPEPYNGRGISYVALGDYDNAFDDFN
CCCEECCCCCEEECCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCHHCCC
TAITLDQNVAESWANQALVYEHNGDKAKAANSYARAVQLDPKYKPAKDGLARTRG
CEEEECHHHHHHHHCCEEEEEECCCCHHHHHHHHHEEECCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]