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The map label for this gene is lldD [H]

Identifier: 225686679

GI number: 225686679

Start: 883774

End: 884919

Strand: Direct

Name: lldD [H]

Synonym: BMEA_B0902

Alternate gene names: 225686679

Gene position: 883774-884919 (Clockwise)

Preceding gene: 225686667

Following gene: 225686680

Centisome position: 74.55

GC content: 57.94

Gene sequence:

>1146_bases
ATGTCCAATATCGTTGAAATCGCCGATCTGAAGCGGCTTGCCCGGCGCCGCGTCCCCAAGATGTTTTTCGACTATGCCGA
TTCTGGCGCCTGGACAGAGTCCACCTACCGGGCAAACGAAGACGACTTCAAGAAGATCAAGCTGCGGCAGCGGGTTCTGG
TTGACATGACCAACCGCTCGCTCGAAACGACCATGATCGGCGAGAAAGTGGCCATGCCCGTGGCGCTTGCCCCGACCGGC
CTGACAGGCATGCAGCATGCCAATGGCGAAATGCTCGCGGCACAGGCGGCAGAAGCTTTCGGTGTTCCCTTCACCCTTTC
CACCATGAGCATCTGCTCCATCGAGGATGTCGCCTCGGTGACGAAGAAGCCGTTCTGGTTCCAGCTCTATGTGATGCGGG
ACCGCGATTTCGTAAAAAACCTGATTGGCCGCGCCAAGGCTGCCGGTTGCTCGGCCCTGGTTCTCACCCTTGATCTCCAG
ATTCTCGGCCAGCGCCACAAGGATATCCGCAACGGCCTTTCCGCTCCGCCGAAATTTACGCCCAAGCATATCTGGCAGAT
GGCGACCTGCCCCGCCTGGTGCCTTGGAATGCTGGGTACGCAGCGGCGCACCTTCCGCAACATTGCCGGCTATGCGAAAA
ATGTTACCGATCTGTCGTCGCTGTCTTCCTGGACGGCAGAACAGTTCGATCCGCAGCTCAACTGGAGCGACGTCGAGTGG
ATCAAGGAACAATGGGGCGGCAAGCTCATCCTCAAGGGTATTCTCGACGTCGAAGATGCCAAAATGGCCGCGAAATCCGG
TGCTGACGCCATTATCGTATCCAATCATGGCGGACGCCAGCTCGACGGCGCCCCCTCATCCATCTCCATGCTGCAACCGA
TTGTTGAAGCCGTGGGCGACAGAATCGAGGTTCATGTCGATGGCGGCATTCGTTCCGGCCAGGACGTGCTGAAAGCGCGC
GCACTCGGCGCACAGGGCGTTTATATCGGCCGTCCGTTCCTTTATGGCCTTGGCGCCATGGGCAACGAAGGCGTGACGCT
TGCACTGGAAATCATCCGCAAGGAAATGGACATCACCATGGCCCTCTGCGGCAAACGCGACATCAATGAAATCGACAAGT
CGATTATCCATTCGATCGATTTCTGA

Upstream 100 bases:

>100_bases
CCGCGAGCCATTTGTTATCGAATTGCTTGTTGGGACTTGATTTCAAGCGCGCGATCCGTCATTCGATTGGTAAAGAAAAC
TGACCACAAAGGGTGGGATG

Downstream 100 bases:

>100_bases
TCTATCCACCAACAGATATAAGGCCCGATAATAGTCGGGCTTTATTCCAGCTTTTTAATAAATATCTTGGTTTATTATGC
CTGCGACTGAGTTAACACCA

Product: FMN-dependent dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MSNIVEIADLKRLARRRVPKMFFDYADSGAWTESTYRANEDDFKKIKLRQRVLVDMTNRSLETTMIGEKVAMPVALAPTG
LTGMQHANGEMLAAQAAEAFGVPFTLSTMSICSIEDVASVTKKPFWFQLYVMRDRDFVKNLIGRAKAAGCSALVLTLDLQ
ILGQRHKDIRNGLSAPPKFTPKHIWQMATCPAWCLGMLGTQRRTFRNIAGYAKNVTDLSSLSSWTAEQFDPQLNWSDVEW
IKEQWGGKLILKGILDVEDAKMAAKSGADAIIVSNHGGRQLDGAPSSISMLQPIVEAVGDRIEVHVDGGIRSGQDVLKAR
ALGAQGVYIGRPFLYGLGAMGNEGVTLALEIIRKEMDITMALCGKRDINEIDKSIIHSIDF

Sequences:

>Translated_381_residues
MSNIVEIADLKRLARRRVPKMFFDYADSGAWTESTYRANEDDFKKIKLRQRVLVDMTNRSLETTMIGEKVAMPVALAPTG
LTGMQHANGEMLAAQAAEAFGVPFTLSTMSICSIEDVASVTKKPFWFQLYVMRDRDFVKNLIGRAKAAGCSALVLTLDLQ
ILGQRHKDIRNGLSAPPKFTPKHIWQMATCPAWCLGMLGTQRRTFRNIAGYAKNVTDLSSLSSWTAEQFDPQLNWSDVEW
IKEQWGGKLILKGILDVEDAKMAAKSGADAIIVSNHGGRQLDGAPSSISMLQPIVEAVGDRIEVHVDGGIRSGQDVLKAR
ALGAQGVYIGRPFLYGLGAMGNEGVTLALEIIRKEMDITMALCGKRDINEIDKSIIHSIDF
>Mature_380_residues
SNIVEIADLKRLARRRVPKMFFDYADSGAWTESTYRANEDDFKKIKLRQRVLVDMTNRSLETTMIGEKVAMPVALAPTGL
TGMQHANGEMLAAQAAEAFGVPFTLSTMSICSIEDVASVTKKPFWFQLYVMRDRDFVKNLIGRAKAAGCSALVLTLDLQI
LGQRHKDIRNGLSAPPKFTPKHIWQMATCPAWCLGMLGTQRRTFRNIAGYAKNVTDLSSLSSWTAEQFDPQLNWSDVEWI
KEQWGGKLILKGILDVEDAKMAAKSGADAIIVSNHGGRQLDGAPSSISMLQPIVEAVGDRIEVHVDGGIRSGQDVLKARA
LGAQGVYIGRPFLYGLGAMGNEGVTLALEIIRKEMDITMALCGKRDINEIDKSIIHSIDF

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=378, Percent_Identity=35.978835978836, Blast_Score=259, Evalue=4e-69,
Organism=Homo sapiens, GI54234014, Length=382, Percent_Identity=37.696335078534, Blast_Score=237, Evalue=2e-62,
Organism=Homo sapiens, GI7705393, Length=382, Percent_Identity=37.696335078534, Blast_Score=237, Evalue=2e-62,
Organism=Escherichia coli, GI1790033, Length=372, Percent_Identity=47.3118279569892, Blast_Score=347, Evalue=6e-97,
Organism=Caenorhabditis elegans, GI193208036, Length=383, Percent_Identity=36.2924281984334, Blast_Score=229, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI32566217, Length=291, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6323587, Length=391, Percent_Identity=33.2480818414322, Blast_Score=202, Evalue=5e-53,
Organism=Drosophila melanogaster, GI281363140, Length=374, Percent_Identity=36.3636363636364, Blast_Score=237, Evalue=8e-63,
Organism=Drosophila melanogaster, GI78707190, Length=374, Percent_Identity=36.3636363636364, Blast_Score=237, Evalue=8e-63,
Organism=Drosophila melanogaster, GI78707188, Length=374, Percent_Identity=35.8288770053476, Blast_Score=237, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 41993; Mature: 41862

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00557 FMN_HYDROXY_ACID_DH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIVEIADLKRLARRRVPKMFFDYADSGAWTESTYRANEDDFKKIKLRQRVLVDMTNRS
CCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
LETTMIGEKVAMPVALAPTGLTGMQHANGEMLAAQAAEAFGVPFTLSTMSICSIEDVASV
HHHHHCCHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHHH
TKKPFWFQLYVMRDRDFVKNLIGRAKAAGCSALVLTLDLQILGQRHKDIRNGLSAPPKFT
HCCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
PKHIWQMATCPAWCLGMLGTQRRTFRNIAGYAKNVTDLSSLSSWTAEQFDPQLNWSDVEW
HHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHH
IKEQWGGKLILKGILDVEDAKMAAKSGADAIIVSNHGGRQLDGAPSSISMLQPIVEAVGD
HHHHCCCEEEEHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
RIEVHVDGGIRSGQDVLKARALGAQGVYIGRPFLYGLGAMGNEGVTLALEIIRKEMDITM
EEEEEECCCCCCCHHHHHHHHCCCCCEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ALCGKRDINEIDKSIIHSIDF
HHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNIVEIADLKRLARRRVPKMFFDYADSGAWTESTYRANEDDFKKIKLRQRVLVDMTNRS
CCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
LETTMIGEKVAMPVALAPTGLTGMQHANGEMLAAQAAEAFGVPFTLSTMSICSIEDVASV
HHHHHCCHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEECHHHHHHHHHHHHH
TKKPFWFQLYVMRDRDFVKNLIGRAKAAGCSALVLTLDLQILGQRHKDIRNGLSAPPKFT
HCCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCC
PKHIWQMATCPAWCLGMLGTQRRTFRNIAGYAKNVTDLSSLSSWTAEQFDPQLNWSDVEW
HHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHH
IKEQWGGKLILKGILDVEDAKMAAKSGADAIIVSNHGGRQLDGAPSSISMLQPIVEAVGD
HHHHCCCEEEEHHHHCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCC
RIEVHVDGGIRSGQDVLKARALGAQGVYIGRPFLYGLGAMGNEGVTLALEIIRKEMDITM
EEEEEECCCCCCCHHHHHHHHCCCCCEEECCHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
ALCGKRDINEIDKSIIHSIDF
HHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA