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The map label for this gene is dcp [H]

Identifier: 225686640

GI number: 225686640

Start: 842112

End: 844160

Strand: Direct

Name: dcp [H]

Synonym: BMEA_B0857

Alternate gene names: 225686640

Gene position: 842112-844160 (Clockwise)

Preceding gene: 225686632

Following gene: 225686644

Centisome position: 71.03

GC content: 59.1

Gene sequence:

>2049_bases
ATGTCCGACAAGCCCCCTTACAATCACGCGCTGAGCGAATGGAACGGACCGCTGGGCCTGCCGGATTTTACCGCCTTCAA
GGACGAGGATTTTGCCCCCGCCTTCGATGTGGCGCTGGCGCAAGACCTGGCGGAAGTGGAAGCCATTGCCGGACAAGCAG
GCGAACCGACCATCGACAATACGCTCAAAGCCCTGCAACTGACAGGCAAGGCGCTGGAGCGCGTTTCCTCCATTTTCTGG
CTGCGCGCAGGCGCGCATACCAACAACACGATCCAGGCGCTGGAGCGCGAAATCGCACCGAAAATGTCGCGTCATTATTC
GCGCATCATGATGGATCCCGCGCTTTTCGCCCGCATCGACGCGCTTGATGAAAATCGCGACATGCTGGACCTCGACAGCG
AAACGAGGCGCGTTCTGGAAAAGACGTGGAAAGGTTTCGTCCGTTCCGGCGCAAAGCTCGATGCGGCAGGCAAGACAGAG
CTTGCAGACATCAATGAGAAGCTTGCGGGGCTTGGTGCGCGCTTCGGCCAGAACGTGCTGAAGGATGAATCCGGCTGGGC
GCTGTTTATCACCGACGAGGCCGATCTTGCCGGTCTGCCGGATTTCCTGAAAAACGCCATGCAGAGTGCTGCTGCCGAGC
GCGGCAAGCCGGATGCATGGGCCGTCACGCTATCGCGCTCGATCGTTGAACCATTCCTTTCTTTCTCGCAGAACCGGAGC
TTGCGCGAACAGGCGTTCAACGCCTGGGCAAAGCGTGGTGAAAATGGCGGCGAAACCGACAATCGCGAGATCGTGCGCGA
GATGGTGGACTTGCGCGAACGCAAGGCCCATTTGCTCGGTTACGCCAATTTTGCCGCCTACAAGCTTGACGATACCATGG
CCAAAACGCCGAAGGCCGTGATGGACCTGCTGGAGCCGGTCTGGAACAAGGCGCGCGCCAAAGCGGCGGAAGAGGAAGCG
GAACTGGAGCGCCTGATCGCAGCCGATGGCGGTAACCACAAGGTCGCGCCATGGGACTGGCGCTTCTATGCCGAAAAGCT
GCGCGCCGAACGCTTCGCCTTCGATGAGGCAGAACTGAAGCCCTATCTTCAGCTAGACAAGATTATCGAAGCCGCTTTCG
ACGTGGCAGGCCGCCTGTTCGGCATCCGCTTTGAGGAAAAGAAGGGCATTGCGACATGGCACCCGGATGTGCGGGTGTTT
CAGGTTTTCAATGCCGATGGCAGCGAACGCGGCCTGTTCCTCGGCGATTATTTCGCCCGCACCTCGAAGCGCTCTGGCGC
ATGGATGAGCTCGCTGCAATCGAGCCACAAGCTTGGCAACGGGCAGAAGCCGATCATCTACAATGTGATGAATTTCGCCA
AGCCCAAGGCGGGCGAACCGGCCCTGCTCTCGCTTGATGATGCGCGCACGCTGTTCCACGAGTTCGGCCATGCGCTGCAT
GGGCTCTTATCGGATGTGACATGGCCTGCCGTTTCCGGCACCGCCGTCTCGCGCGATTTCGTGGAACTGCCATCGCAGCT
TTACGAACACTGGCTGACCGTTCCAGCCGTTCTCGAAAAATACGCCGTGCACTATCGCACCGGCGAAGCCATGCCGAAGG
CGCTTCTCGACAAGGTGCTTGCCGCACGCACCTTCAATGCGGGCTTCAACACAGTGGAGTTTACCTCATCCGCCTTGGTG
GACATGGCCTTCCACACCGGCAAGGAAAAGATTGCCGACCCACTGGCTTTTGAAAAGCAGACGCTGGCAAAGCTTTCCAT
GCCGGATGCAATCATCATGCGGCACCGCACGCCGCATTTTACCCACGTCTTCTCCGGCGACGGCTATTCGGCAGGCTACT
ATTCCTACATGTGGTCGGAAGTGCTGGATGCGGACGCTTTCTCGGCCTTTGAGGAGACCGGCGACGCCTTCAACCCGGAA
CTGGCGGCAAAGCTGAAACAGCATATCTATGCCGCTGGCGGCAGCCGCGACCCGGAAGAGCTTTACAAAGCCTTCCGCGG
CAAGATGCCGACCCCGGACGCGATGATTGAAAAGCGTGGTTTGAATTAA

Upstream 100 bases:

>100_bases
TTTCATGAAAACAGGCATGCTTGACTCGAAATCCTTGCCCGCCTGCCATGCAATGCCTAGGTTCAGGCTATATCGAAATC
ATTTGGTCTGGAGTTTCATC

Downstream 100 bases:

>100_bases
ACAAAAGAGGCCGGGGAAACCGGCCTTTTTCAATGCTTGTGGGTCAGAATATTCACGAGGCGCCCATAAGAGTCGCGCGT
GTAGAAACGACGCACGCCCC

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 682; Mature: 681

Protein sequence:

>682_residues
MSDKPPYNHALSEWNGPLGLPDFTAFKDEDFAPAFDVALAQDLAEVEAIAGQAGEPTIDNTLKALQLTGKALERVSSIFW
LRAGAHTNNTIQALEREIAPKMSRHYSRIMMDPALFARIDALDENRDMLDLDSETRRVLEKTWKGFVRSGAKLDAAGKTE
LADINEKLAGLGARFGQNVLKDESGWALFITDEADLAGLPDFLKNAMQSAAAERGKPDAWAVTLSRSIVEPFLSFSQNRS
LREQAFNAWAKRGENGGETDNREIVREMVDLRERKAHLLGYANFAAYKLDDTMAKTPKAVMDLLEPVWNKARAKAAEEEA
ELERLIAADGGNHKVAPWDWRFYAEKLRAERFAFDEAELKPYLQLDKIIEAAFDVAGRLFGIRFEEKKGIATWHPDVRVF
QVFNADGSERGLFLGDYFARTSKRSGAWMSSLQSSHKLGNGQKPIIYNVMNFAKPKAGEPALLSLDDARTLFHEFGHALH
GLLSDVTWPAVSGTAVSRDFVELPSQLYEHWLTVPAVLEKYAVHYRTGEAMPKALLDKVLAARTFNAGFNTVEFTSSALV
DMAFHTGKEKIADPLAFEKQTLAKLSMPDAIIMRHRTPHFTHVFSGDGYSAGYYSYMWSEVLDADAFSAFEETGDAFNPE
LAAKLKQHIYAAGGSRDPEELYKAFRGKMPTPDAMIEKRGLN

Sequences:

>Translated_682_residues
MSDKPPYNHALSEWNGPLGLPDFTAFKDEDFAPAFDVALAQDLAEVEAIAGQAGEPTIDNTLKALQLTGKALERVSSIFW
LRAGAHTNNTIQALEREIAPKMSRHYSRIMMDPALFARIDALDENRDMLDLDSETRRVLEKTWKGFVRSGAKLDAAGKTE
LADINEKLAGLGARFGQNVLKDESGWALFITDEADLAGLPDFLKNAMQSAAAERGKPDAWAVTLSRSIVEPFLSFSQNRS
LREQAFNAWAKRGENGGETDNREIVREMVDLRERKAHLLGYANFAAYKLDDTMAKTPKAVMDLLEPVWNKARAKAAEEEA
ELERLIAADGGNHKVAPWDWRFYAEKLRAERFAFDEAELKPYLQLDKIIEAAFDVAGRLFGIRFEEKKGIATWHPDVRVF
QVFNADGSERGLFLGDYFARTSKRSGAWMSSLQSSHKLGNGQKPIIYNVMNFAKPKAGEPALLSLDDARTLFHEFGHALH
GLLSDVTWPAVSGTAVSRDFVELPSQLYEHWLTVPAVLEKYAVHYRTGEAMPKALLDKVLAARTFNAGFNTVEFTSSALV
DMAFHTGKEKIADPLAFEKQTLAKLSMPDAIIMRHRTPHFTHVFSGDGYSAGYYSYMWSEVLDADAFSAFEETGDAFNPE
LAAKLKQHIYAAGGSRDPEELYKAFRGKMPTPDAMIEKRGLN
>Mature_681_residues
SDKPPYNHALSEWNGPLGLPDFTAFKDEDFAPAFDVALAQDLAEVEAIAGQAGEPTIDNTLKALQLTGKALERVSSIFWL
RAGAHTNNTIQALEREIAPKMSRHYSRIMMDPALFARIDALDENRDMLDLDSETRRVLEKTWKGFVRSGAKLDAAGKTEL
ADINEKLAGLGARFGQNVLKDESGWALFITDEADLAGLPDFLKNAMQSAAAERGKPDAWAVTLSRSIVEPFLSFSQNRSL
REQAFNAWAKRGENGGETDNREIVREMVDLRERKAHLLGYANFAAYKLDDTMAKTPKAVMDLLEPVWNKARAKAAEEEAE
LERLIAADGGNHKVAPWDWRFYAEKLRAERFAFDEAELKPYLQLDKIIEAAFDVAGRLFGIRFEEKKGIATWHPDVRVFQ
VFNADGSERGLFLGDYFARTSKRSGAWMSSLQSSHKLGNGQKPIIYNVMNFAKPKAGEPALLSLDDARTLFHEFGHALHG
LLSDVTWPAVSGTAVSRDFVELPSQLYEHWLTVPAVLEKYAVHYRTGEAMPKALLDKVLAARTFNAGFNTVEFTSSALVD
MAFHTGKEKIADPLAFEKQTLAKLSMPDAIIMRHRTPHFTHVFSGDGYSAGYYSYMWSEVLDADAFSAFEETGDAFNPEL
AAKLKQHIYAAGGSRDPEELYKAFRGKMPTPDAMIEKRGLN

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=641, Percent_Identity=31.201248049922, Blast_Score=252, Evalue=8e-67,
Organism=Homo sapiens, GI14149738, Length=643, Percent_Identity=27.8382581648523, Blast_Score=222, Evalue=7e-58,
Organism=Homo sapiens, GI156105687, Length=676, Percent_Identity=24.2603550295858, Blast_Score=179, Evalue=6e-45,
Organism=Escherichia coli, GI1787819, Length=671, Percent_Identity=40.2384500745156, Blast_Score=477, Evalue=1e-135,
Organism=Escherichia coli, GI1789913, Length=679, Percent_Identity=34.1678939617084, Blast_Score=385, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI32565901, Length=627, Percent_Identity=22.6475279106858, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71999758, Length=524, Percent_Identity=20.9923664122137, Blast_Score=83, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319793, Length=572, Percent_Identity=27.7972027972028, Blast_Score=213, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6322715, Length=466, Percent_Identity=26.3948497854077, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI21356111, Length=551, Percent_Identity=25.2268602540835, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI20129717, Length=492, Percent_Identity=24.1869918699187, Blast_Score=142, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 76035; Mature: 75903

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKPPYNHALSEWNGPLGLPDFTAFKDEDFAPAFDVALAQDLAEVEAIAGQAGEPTIDN
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
TLKALQLTGKALERVSSIFWLRAGAHTNNTIQALEREIAPKMSRHYSRIMMDPALFARID
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ALDENRDMLDLDSETRRVLEKTWKGFVRSGAKLDAAGKTELADINEKLAGLGARFGQNVL
HHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KDESGWALFITDEADLAGLPDFLKNAMQSAAAERGKPDAWAVTLSRSIVEPFLSFSQNRS
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCH
LREQAFNAWAKRGENGGETDNREIVREMVDLRERKAHLLGYANFAAYKLDDTMAKTPKAV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHCCHHHH
MDLLEPVWNKARAKAAEEEAELERLIAADGGNHKVAPWDWRFYAEKLRAERFAFDEAELK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCC
PYLQLDKIIEAAFDVAGRLFGIRFEEKKGIATWHPDVRVFQVFNADGSERGLFLGDYFAR
HHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEECCCCEEEEEECCCCCCCCCEEHHHHHH
TSKRSGAWMSSLQSSHKLGNGQKPIIYNVMNFAKPKAGEPALLSLDDARTLFHEFGHALH
HCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHH
GLLSDVTWPAVSGTAVSRDFVELPSQLYEHWLTVPAVLEKYAVHYRTGEAMPKALLDKVL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AARTFNAGFNTVEFTSSALVDMAFHTGKEKIADPLAFEKQTLAKLSMPDAIIMRHRTPHF
HHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCHHHHHHCCCCCE
THVFSGDGYSAGYYSYMWSEVLDADAFSAFEETGDAFNPELAAKLKQHIYAAGGSRDPEE
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHH
LYKAFRGKMPTPDAMIEKRGLN
HHHHHCCCCCCCHHHHHHCCCC
>Mature Secondary Structure 
SDKPPYNHALSEWNGPLGLPDFTAFKDEDFAPAFDVALAQDLAEVEAIAGQAGEPTIDN
CCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHH
TLKALQLTGKALERVSSIFWLRAGAHTNNTIQALEREIAPKMSRHYSRIMMDPALFARID
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ALDENRDMLDLDSETRRVLEKTWKGFVRSGAKLDAAGKTELADINEKLAGLGARFGQNVL
HHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KDESGWALFITDEADLAGLPDFLKNAMQSAAAERGKPDAWAVTLSRSIVEPFLSFSQNRS
CCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCH
LREQAFNAWAKRGENGGETDNREIVREMVDLRERKAHLLGYANFAAYKLDDTMAKTPKAV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHCCHHHH
MDLLEPVWNKARAKAAEEEAELERLIAADGGNHKVAPWDWRFYAEKLRAERFAFDEAELK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHCC
PYLQLDKIIEAAFDVAGRLFGIRFEEKKGIATWHPDVRVFQVFNADGSERGLFLGDYFAR
HHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEECCCCEEEEEECCCCCCCCCEEHHHHHH
TSKRSGAWMSSLQSSHKLGNGQKPIIYNVMNFAKPKAGEPALLSLDDARTLFHEFGHALH
HCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHH
GLLSDVTWPAVSGTAVSRDFVELPSQLYEHWLTVPAVLEKYAVHYRTGEAMPKALLDKVL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AARTFNAGFNTVEFTSSALVDMAFHTGKEKIADPLAFEKQTLAKLSMPDAIIMRHRTPHF
HHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHHCCCHHHHHHCCCCCE
THVFSGDGYSAGYYSYMWSEVLDADAFSAFEETGDAFNPELAAKLKQHIYAAGGSRDPEE
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHH
LYKAFRGKMPTPDAMIEKRGLN
HHHHHCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]