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The map label for this gene is agaR [H]

Identifier: 225686630

GI number: 225686630

Start: 832949

End: 833713

Strand: Direct

Name: agaR [H]

Synonym: BMEA_B0847

Alternate gene names: 225686630

Gene position: 832949-833713 (Clockwise)

Preceding gene: 225686629

Following gene: 225686631

Centisome position: 70.26

GC content: 57.52

Gene sequence:

>765_bases
GTGAAGCGCGACGACAGACGACAGGCGATCATAAACCTTCTTATCGAAAATCAGGCCGTCGATCTTGACGATCTGGCGGG
GCGGTTTGCCGTTTCCAAGATGACGATCCATCGTGATCTGGATTCACTGGAACAGTCCGGCGTACTGCGCAAGGTACGCG
GCGGCGCGACGATCGGCGCGGGCACACAATTCGAGAGTGATTTCCGTTTTCGCGAGCGGCAGGACGGCGAAGCCAAGCTG
AAGATGGCCCGCGCAGCACTTGAGCTTGTGGAACCCGGCATGACCGTGATGGTCAATGATGGTTCCATGGCTGCCCTTCT
GGGCGGCATGTTGCGGGAAAAGCGCCCGCTCACCGTCATCACCAACAATGCCGTCATCATTGATGAGCTGAAAGGTGAAA
ACGGGATCAACCTTATTGCGCTCGGCGGCACCTATTCGGCAAAGTTCAACGCCTTTTTCGGTATTTTGACGGAAGAAGCA
TTGGCGCGCCTCAGCGCCGACATTGCCTTTGTCTCATCGCCTGCCGTCAACGGGCAACTGGTCTATCACATGGACGAAAA
CGTGGTGCGCACCAAGCGCGCCATGACGAATGCCGCCGCACGCTCGTGCCTTCTGGTCAACCACCAGCGTTTCGGGCGCC
CTGCCCTACATGTGATGGCCGACCTTACCGATTTTGACGCGATCATCACCGATGCATCCCCCGGCACGGCGGTTTTGAAC
GGACTGAAACAGGCCGGGATCAAACTGACAATAGCAGCAGACTAG

Upstream 100 bases:

>100_bases
GAATGGAAAATAACAAAATCACATTTTTGCCGTGGATTTTTTTGTGATTTTGTGATCTAACTTCGTGCGATAATGTTCCG
CCCAACAGATCGGATAAAGC

Downstream 100 bases:

>100_bases
GAACAGTTACGCATGACCAAATTCTGGATTGGCACAAGCTGGAAAATGAACAAGACGCTGGCCGAAGCCCGCCTTTTCGC
GGAAGCGCTGAAAGCCGCCG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MKRDDRRQAIINLLIENQAVDLDDLAGRFAVSKMTIHRDLDSLEQSGVLRKVRGGATIGAGTQFESDFRFRERQDGEAKL
KMARAALELVEPGMTVMVNDGSMAALLGGMLREKRPLTVITNNAVIIDELKGENGINLIALGGTYSAKFNAFFGILTEEA
LARLSADIAFVSSPAVNGQLVYHMDENVVRTKRAMTNAAARSCLLVNHQRFGRPALHVMADLTDFDAIITDASPGTAVLN
GLKQAGIKLTIAAD

Sequences:

>Translated_254_residues
MKRDDRRQAIINLLIENQAVDLDDLAGRFAVSKMTIHRDLDSLEQSGVLRKVRGGATIGAGTQFESDFRFRERQDGEAKL
KMARAALELVEPGMTVMVNDGSMAALLGGMLREKRPLTVITNNAVIIDELKGENGINLIALGGTYSAKFNAFFGILTEEA
LARLSADIAFVSSPAVNGQLVYHMDENVVRTKRAMTNAAARSCLLVNHQRFGRPALHVMADLTDFDAIITDASPGTAVLN
GLKQAGIKLTIAAD
>Mature_254_residues
MKRDDRRQAIINLLIENQAVDLDDLAGRFAVSKMTIHRDLDSLEQSGVLRKVRGGATIGAGTQFESDFRFRERQDGEAKL
KMARAALELVEPGMTVMVNDGSMAALLGGMLREKRPLTVITNNAVIIDELKGENGINLIALGGTYSAKFNAFFGILTEEA
LARLSADIAFVSSPAVNGQLVYHMDENVVRTKRAMTNAAARSCLLVNHQRFGRPALHVMADLTDFDAIITDASPGTAVLN
GLKQAGIKLTIAAD

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=27.2727272727273, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788069, Length=253, Percent_Identity=30.8300395256917, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI226510968, Length=227, Percent_Identity=29.5154185022026, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789829, Length=254, Percent_Identity=27.1653543307087, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1789059, Length=257, Percent_Identity=26.8482490272374, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=25.3968253968254, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1787540, Length=251, Percent_Identity=28.2868525896414, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=29.3103448275862, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787063, Length=255, Percent_Identity=26.2745098039216, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082344, Length=256, Percent_Identity=25, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27483; Mature: 27483

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRDDRRQAIINLLIENQAVDLDDLAGRFAVSKMTIHRDLDSLEQSGVLRKVRGGATIGA
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEECC
GTQFESDFRFRERQDGEAKLKMARAALELVEPGMTVMVNDGSMAALLGGMLREKRPLTVI
CCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCEEEE
TNNAVIIDELKGENGINLIALGGTYSAKFNAFFGILTEEALARLSADIAFVSSPAVNGQL
ECCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEE
VYHMDENVVRTKRAMTNAAARSCLLVNHQRFGRPALHVMADLTDFDAIITDASPGTAVLN
EEEECCHHHHHHHHHHHHHHHHEEEECCHHHCCHHHHHHHHHHHHHEEEECCCCHHHHHH
GLKQAGIKLTIAAD
HHHHCCEEEEEEEC
>Mature Secondary Structure
MKRDDRRQAIINLLIENQAVDLDDLAGRFAVSKMTIHRDLDSLEQSGVLRKVRGGATIGA
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEECC
GTQFESDFRFRERQDGEAKLKMARAALELVEPGMTVMVNDGSMAALLGGMLREKRPLTVI
CCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCEEEE
TNNAVIIDELKGENGINLIALGGTYSAKFNAFFGILTEEALARLSADIAFVSSPAVNGQL
ECCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEE
VYHMDENVVRTKRAMTNAAARSCLLVNHQRFGRPALHVMADLTDFDAIITDASPGTAVLN
EEEECCHHHHHHHHHHHHHHHHEEEECCHHHCCHHHHHHHHHHHHHEEEECCCCHHHHHH
GLKQAGIKLTIAAD
HHHHCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]