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The map label for this gene is glpD [H]

Identifier: 225686627

GI number: 225686627

Start: 829435

End: 830943

Strand: Direct

Name: glpD [H]

Synonym: BMEA_B0844

Alternate gene names: 225686627

Gene position: 829435-830943 (Clockwise)

Preceding gene: 225686626

Following gene: 225686628

Centisome position: 69.96

GC content: 60.44

Gene sequence:

>1509_bases
ATGGCTGAACCGGAAACCTGCGACCTGTTTGTAATTGGCGGCGGCATCAACGGTGCGGGCGTGGCCCGCGACGCGGCCGG
GCGCGGCCTCAAGGTGGTGCTGGCAGAAAAGGACGATCTGGCGCAAGGCACATCATCGCGCTCCGGCAAGCTGGTGCATG
GCGGTTTGCGCTATCTCGAATATTATGAGTTCCGCCTTGTGCGCGAAGCGCTGATCGAGCGCGAAGTGCTTTTGAATGCG
GCACCCCATATCATCTGGCCGATGCGCTTCGTGCTGCCGCACAGCCCGCAGGATCGCCCGGCCTGGCTGGTGCGGCTTGG
CCTGTTTCTCTATGACCATCTGGGCGGGCGCAAAAAACTTCCCGGCACGCGTACGCTCGATCTGAAGCGCGACCCGGAAG
GCACGCCGATCCTCGACCAGTACACCAAGGGTTTTGAATATTCCGATTGCTGGGTGGACGATGCGCGCCTCGTGGCGCTC
AATGCGGTGGGTGCCGCCGAAAAGGGCGCGACCATTCTCACCCGTACACCGGTCGTCTCCGCACGCCGCGAAAATGGCGG
CTGGATCGTGGAAACCAGAAACAGCGATACCGGCGAAACCCACACCTTCCGCGCCCGCTGCATCGTCAATTGCGCCGGAC
CATGGGTCACGGACGTCATCCACAATGTCGCTGCCTCCACCTCGTCGCGCAATGTGCGCCTCGTCAAGGGCAGCCACATC
ATCGTTCCGAAATTCTGGTCGGGCGCAAACGCCTATCTCGTTCAGAACCACGACAAGCGCGTGATCTTCATCAATCCATA
TGAAGGTGACAAGGCGCTGATCGGCACCACCGACATTGCCTATGAAGGCCGGGCGGAAGACGTTGCGGCGGATGAGAAGG
AAATCGACTATCTCATCACCGCGGTAAACCGCTATTTCAAGGAAAAGCTCCGGCGCGAAGACGTGCTGCACTCCTTCTCC
GGCGTGCGCCCGCTGTTTGACGACGGCAAGGGCAATCCTTCCGCCGTCACCCGCGATTACGTGTTCGATCTGGACGAAAC
CGGCGGTGCACCGCTGCTCAACGTCTTTGGCGGCAAGATCACCACCTTCCGCGAACTGGCGGAGCGCGGGGTGCATCGGC
TCAAGCACATTTTCCCGCAAATGGGCGGCGACTGGACCCACGACGCGCCGCTGCCCGGCGGCGAGATTGCCAATGCCGAT
TATGAAACCTTCGCCAATACCTTACGCGACACCTATCCATGGATGCCGCGCACACTCGTTCATCATTATGGACGGCTCTA
TGGTGCGCGCACAAAGGATGTGGTGGCTGGCGCGCAGAACCTCGAAGGGCTTGGCCGTCACTTCGGCGGCGATTTCCATG
AGGCGGAAGTGCGCTATCTGGTGGCCAGAGAATGGGCAAAGACGGCAGAAGACATTCTCTATCGCCGCACCAAGCATTAC
CTGCATTTGACCGAAGCCGAACGCGCCGCTTTCGTGGAATGGTTCGACAACGCCAATCTAGTTGCTTGA

Upstream 100 bases:

>100_bases
GCACCAATATGAAGAACTTTTCGTTGCCTATCGGGAAGCGCGGCTGGCTCTTGCGCCAGTCTGGGACAAACTCGCTTCCG
GCAAATAAGGAAACATTGAA

Downstream 100 bases:

>100_bases
GGACGATATGGCCCTGACGCTTTCGCTCAACACCAATCCGCTGGTCAACCGCTTTGCCGAGCCGGACGACCTGATCGAAA
CGGTTGCCCGCGACCTGCGC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MAEPETCDLFVIGGGINGAGVARDAAGRGLKVVLAEKDDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVLLNA
APHIIWPMRFVLPHSPQDRPAWLVRLGLFLYDHLGGRKKLPGTRTLDLKRDPEGTPILDQYTKGFEYSDCWVDDARLVAL
NAVGAAEKGATILTRTPVVSARRENGGWIVETRNSDTGETHTFRARCIVNCAGPWVTDVIHNVAASTSSRNVRLVKGSHI
IVPKFWSGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADEKEIDYLITAVNRYFKEKLRREDVLHSFS
GVRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKITTFRELAERGVHRLKHIFPQMGGDWTHDAPLPGGEIANAD
YETFANTLRDTYPWMPRTLVHHYGRLYGARTKDVVAGAQNLEGLGRHFGGDFHEAEVRYLVAREWAKTAEDILYRRTKHY
LHLTEAERAAFVEWFDNANLVA

Sequences:

>Translated_502_residues
MAEPETCDLFVIGGGINGAGVARDAAGRGLKVVLAEKDDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVLLNA
APHIIWPMRFVLPHSPQDRPAWLVRLGLFLYDHLGGRKKLPGTRTLDLKRDPEGTPILDQYTKGFEYSDCWVDDARLVAL
NAVGAAEKGATILTRTPVVSARRENGGWIVETRNSDTGETHTFRARCIVNCAGPWVTDVIHNVAASTSSRNVRLVKGSHI
IVPKFWSGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADEKEIDYLITAVNRYFKEKLRREDVLHSFS
GVRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKITTFRELAERGVHRLKHIFPQMGGDWTHDAPLPGGEIANAD
YETFANTLRDTYPWMPRTLVHHYGRLYGARTKDVVAGAQNLEGLGRHFGGDFHEAEVRYLVAREWAKTAEDILYRRTKHY
LHLTEAERAAFVEWFDNANLVA
>Mature_501_residues
AEPETCDLFVIGGGINGAGVARDAAGRGLKVVLAEKDDLAQGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVLLNAA
PHIIWPMRFVLPHSPQDRPAWLVRLGLFLYDHLGGRKKLPGTRTLDLKRDPEGTPILDQYTKGFEYSDCWVDDARLVALN
AVGAAEKGATILTRTPVVSARRENGGWIVETRNSDTGETHTFRARCIVNCAGPWVTDVIHNVAASTSSRNVRLVKGSHII
VPKFWSGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADEKEIDYLITAVNRYFKEKLRREDVLHSFSG
VRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKITTFRELAERGVHRLKHIFPQMGGDWTHDAPLPGGEIANADY
ETFANTLRDTYPWMPRTLVHHYGRLYGARTKDVVAGAQNLEGLGRHFGGDFHEAEVRYLVAREWAKTAEDILYRRTKHYL
HLTEAERAAFVEWFDNANLVA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=525, Percent_Identity=32.1904761904762, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI285002231, Length=525, Percent_Identity=32.1904761904762, Blast_Score=206, Evalue=5e-53,
Organism=Escherichia coli, GI2367226, Length=492, Percent_Identity=50.2032520325203, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1788574, Length=388, Percent_Identity=27.8350515463918, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI115534726, Length=513, Percent_Identity=31.1890838206628, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17509253, Length=506, Percent_Identity=31.2252964426877, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6322036, Length=537, Percent_Identity=29.4227188081937, Blast_Score=186, Evalue=9e-48,
Organism=Drosophila melanogaster, GI161077125, Length=517, Percent_Identity=31.1411992263056, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24653942, Length=517, Percent_Identity=31.1411992263056, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24653944, Length=517, Percent_Identity=31.1411992263056, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI20130025, Length=517, Percent_Identity=31.1411992263056, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24586295, Length=506, Percent_Identity=28.6561264822134, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI19921278, Length=490, Percent_Identity=22.8571428571429, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56140; Mature: 56009

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPETCDLFVIGGGINGAGVARDAAGRGLKVVLAEKDDLAQGTSSRSGKLVHGGLRYLE
CCCCCCEEEEEEECCCCCCCCCHHCCCCCEEEEEECCCCHHCCCCCCCCCEEEHHHHHHH
YYEFRLVREALIEREVLLNAAPHIIWPMRFVLPHSPQDRPAWLVRLGLFLYDHLGGRKKL
HHHHHHHHHHHHHHHHHHHCCCCCEECHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PGTRTLDLKRDPEGTPILDQYTKGFEYSDCWVDDARLVALNAVGAAEKGATILTRTPVVS
CCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCE
ARRENGGWIVETRNSDTGETHTFRARCIVNCAGPWVTDVIHNVAASTSSRNVRLVKGSHI
EEECCCCEEEECCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCEE
IVPKFWSGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADEKEIDYLIT
EEEECCCCCCEEEEECCCCEEEEEECCCCCEEEEECCCEEECCCCCCCCCCHHHHHHHHH
AVNRYFKEKLRREDVLHSFSGVRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCH
TTFRELAERGVHRLKHIFPQMGGDWTHDAPLPGGEIANADYETFANTLRDTYPWMPRTLV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
HHYGRLYGARTKDVVAGAQNLEGLGRHFGGDFHEAEVRYLVAREWAKTAEDILYRRTKHY
HHHHHHHCCCCHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
LHLTEAERAAFVEWFDNANLVA
EEEEHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AEPETCDLFVIGGGINGAGVARDAAGRGLKVVLAEKDDLAQGTSSRSGKLVHGGLRYLE
CCCCCEEEEEEECCCCCCCCCHHCCCCCEEEEEECCCCHHCCCCCCCCCEEEHHHHHHH
YYEFRLVREALIEREVLLNAAPHIIWPMRFVLPHSPQDRPAWLVRLGLFLYDHLGGRKKL
HHHHHHHHHHHHHHHHHHHCCCCCEECHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
PGTRTLDLKRDPEGTPILDQYTKGFEYSDCWVDDARLVALNAVGAAEKGATILTRTPVVS
CCCEEEEECCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCE
ARRENGGWIVETRNSDTGETHTFRARCIVNCAGPWVTDVIHNVAASTSSRNVRLVKGSHI
EEECCCCEEEECCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCEE
IVPKFWSGANAYLVQNHDKRVIFINPYEGDKALIGTTDIAYEGRAEDVAADEKEIDYLIT
EEEECCCCCCEEEEECCCCEEEEEECCCCCEEEEECCCEEECCCCCCCCCCHHHHHHHHH
AVNRYFKEKLRREDVLHSFSGVRPLFDDGKGNPSAVTRDYVFDLDETGGAPLLNVFGGKI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHCCCCH
TTFRELAERGVHRLKHIFPQMGGDWTHDAPLPGGEIANADYETFANTLRDTYPWMPRTLV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHH
HHYGRLYGARTKDVVAGAQNLEGLGRHFGGDFHEAEVRYLVAREWAKTAEDILYRRTKHY
HHHHHHHCCCCHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHE
LHLTEAERAAFVEWFDNANLVA
EEEEHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]