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The map label for this gene is mdtA [H]

Identifier: 225686579

GI number: 225686579

Start: 782526

End: 783512

Strand: Reverse

Name: mdtA [H]

Synonym: BMEA_B0795

Alternate gene names: 225686579

Gene position: 783512-782526 (Counterclockwise)

Preceding gene: 225686583

Following gene: 225686578

Centisome position: 66.09

GC content: 58.36

Gene sequence:

>987_bases
GTGCTGCGCAATACGGTCGGCACTGCCGTGGCAATAGCGTCAACGGCGGTCAACAGCCCGGAAGCGGGCAATGTGGCGGT
GTTGGCAGTGAAGGATGGTGCCATTGTCAAGGCGGGCGACCTTATCGCCCAGCTTGACGACAAGGCAATCCGCGCAAATA
TCGTAAAGGATACGGCTTCCCTCGCGAAGTCGCAGGCCACGCTGAACGGTGCGGAAATTCAGCTCAAACGTACGCAGGAT
CTGGTTCGGAAGGGGGGCGCCACGTCGCAGAGTGGCGATGATGCCCTGGCCGCATTGAAGGTGGCGCAAGCACAGCTACA
GGTCGATCAGGCGCAACTTGCGGCGGATCAGGTGACGCTTTCCTATACAAAAATCGTGGCGCCCTTTACCGGGCAACTGG
GCGTCGTTCAGGTTTCTCCGGGTGCTTATCTTTCTGCTGGCTCATCGGTTGCTACCCTCACCCGGATGTCACCGATCTAT
GCGGAGTTCACTCTTCCCGAAACGGACCTTGCGCGCATAAGGGCAGCCCTCAAGGACGGCACGTTGAAAACGGATGTGAC
GGTGACTTCCGGCGAGGGAAAGGATGTCACCGAAAGCGGCCGCGTCGATTTCATCGACAATGCAGTCGATCCGGCCAGTG
GTACAGTGCGCTTGCGGGCGACGCTCGACAACCGATCCGGCAATTTCTGGCCGGGACAATCCCTGCGCATTTCAGTTGAA
TTGGGTAAGATCGATGATCTGGTGCTGGTTCCCGATGTCGCCGTGGAGCCACAGGAAAACGGTTCCATCAGTTATGTGGT
CAAGCCTGACAATTCCGTCGAAATCAGACCTGTGAGCGTGGCCTTGCGTGCTGATGGCATGGCCGGCGTGCGGGCAGGCC
TTCAACCGGGCGAAAGAGTGGTTATCGAAGGGCAGGATGCTCTTTCCAACGGCAACCGGGTAAAACTGGTCGAGACGAAG
CCAGATGCCAAGGTTTCATCCGACTGA

Upstream 100 bases:

>100_bases
CATCACCAACCGCTCAGATCGGCGCCAAGCGAGGGAGCAACCGCGCGCCAGTATCGAGCGCCCGGTCAAAGTCGCGCTTG
CAAAATCAGGCTCGCTGCCA

Downstream 100 bases:

>100_bases
TCCTTTTTGAAGGCGGACAGGCATGAATATTTCCGAAGTCTTCATTCGCCGTCCGGTTGCGACAATCCTGCTGGTGATAG
GCGGGTTGATTGGCGGGATT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MLRNTVGTAVAIASTAVNSPEAGNVAVLAVKDGAIVKAGDLIAQLDDKAIRANIVKDTASLAKSQATLNGAEIQLKRTQD
LVRKGGATSQSGDDALAALKVAQAQLQVDQAQLAADQVTLSYTKIVAPFTGQLGVVQVSPGAYLSAGSSVATLTRMSPIY
AEFTLPETDLARIRAALKDGTLKTDVTVTSGEGKDVTESGRVDFIDNAVDPASGTVRLRATLDNRSGNFWPGQSLRISVE
LGKIDDLVLVPDVAVEPQENGSISYVVKPDNSVEIRPVSVALRADGMAGVRAGLQPGERVVIEGQDALSNGNRVKLVETK
PDAKVSSD

Sequences:

>Translated_328_residues
MLRNTVGTAVAIASTAVNSPEAGNVAVLAVKDGAIVKAGDLIAQLDDKAIRANIVKDTASLAKSQATLNGAEIQLKRTQD
LVRKGGATSQSGDDALAALKVAQAQLQVDQAQLAADQVTLSYTKIVAPFTGQLGVVQVSPGAYLSAGSSVATLTRMSPIY
AEFTLPETDLARIRAALKDGTLKTDVTVTSGEGKDVTESGRVDFIDNAVDPASGTVRLRATLDNRSGNFWPGQSLRISVE
LGKIDDLVLVPDVAVEPQENGSISYVVKPDNSVEIRPVSVALRADGMAGVRAGLQPGERVVIEGQDALSNGNRVKLVETK
PDAKVSSD
>Mature_328_residues
MLRNTVGTAVAIASTAVNSPEAGNVAVLAVKDGAIVKAGDLIAQLDDKAIRANIVKDTASLAKSQATLNGAEIQLKRTQD
LVRKGGATSQSGDDALAALKVAQAQLQVDQAQLAADQVTLSYTKIVAPFTGQLGVVQVSPGAYLSAGSSVATLTRMSPIY
AEFTLPETDLARIRAALKDGTLKTDVTVTSGEGKDVTESGRVDFIDNAVDPASGTVRLRATLDNRSGNFWPGQSLRISVE
LGKIDDLVLVPDVAVEPQENGSISYVVKPDNSVEIRPVSVALRADGMAGVRAGLQPGERVVIEGQDALSNGNRVKLVETK
PDAKVSSD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=328, Percent_Identity=29.2682926829268, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789929, Length=296, Percent_Identity=27.7027027027027, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786668, Length=302, Percent_Identity=31.7880794701987, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789665, Length=299, Percent_Identity=29.4314381270903, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 34111; Mature: 34111

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRNTVGTAVAIASTAVNSPEAGNVAVLAVKDGAIVKAGDLIAQLDDKAIRANIVKDTAS
CCCCCCCCEEEEEEHHCCCCCCCCEEEEEEECCCEEECCHHHHHCCCCHHEEHHHHHHHH
LAKSQATLNGAEIQLKRTQDLVRKGGATSQSGDDALAALKVAQAQLQVDQAQLAADQVTL
HHHHHHCCCCEEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
SYTKIVAPFTGQLGVVQVSPGAYLSAGSSVATLTRMSPIYAEFTLPETDLARIRAALKDG
EEEEEEECCCCCEEEEEECCCCEEECCCCEEEHHHCCCEEEEEECCCHHHHHHHHHHHCC
TLKTDVTVTSGEGKDVTESGRVDFIDNAVDPASGTVRLRATLDNRSGNFWPGQSLRISVE
CEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEE
LGKIDDLVLVPDVAVEPQENGSISYVVKPDNSVEIRPVSVALRADGMAGVRAGLQPGERV
ECCCCCEEEECCCEECCCCCCCEEEEECCCCCEEEEEEEEEEECCCCHHHHCCCCCCCEE
VIEGQDALSNGNRVKLVETKPDAKVSSD
EEECCHHHCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MLRNTVGTAVAIASTAVNSPEAGNVAVLAVKDGAIVKAGDLIAQLDDKAIRANIVKDTAS
CCCCCCCCEEEEEEHHCCCCCCCCEEEEEEECCCEEECCHHHHHCCCCHHEEHHHHHHHH
LAKSQATLNGAEIQLKRTQDLVRKGGATSQSGDDALAALKVAQAQLQVDQAQLAADQVTL
HHHHHHCCCCEEEEEEHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
SYTKIVAPFTGQLGVVQVSPGAYLSAGSSVATLTRMSPIYAEFTLPETDLARIRAALKDG
EEEEEEECCCCCEEEEEECCCCEEECCCCEEEHHHCCCEEEEEECCCHHHHHHHHHHHCC
TLKTDVTVTSGEGKDVTESGRVDFIDNAVDPASGTVRLRATLDNRSGNFWPGQSLRISVE
CEEEEEEEECCCCCCCCCCCCEEEECCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEEEE
LGKIDDLVLVPDVAVEPQENGSISYVVKPDNSVEIRPVSVALRADGMAGVRAGLQPGERV
ECCCCCEEEECCCEECCCCCCCEEEEECCCCCEEEEEEEEEEECCCCHHHHCCCCCCCEE
VIEGQDALSNGNRVKLVETKPDAKVSSD
EEECCHHHCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]