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The map label for this gene is 225686432

Identifier: 225686432

GI number: 225686432

Start: 614324

End: 615364

Strand: Direct

Name: 225686432

Synonym: BMEA_B0627

Alternate gene names: NA

Gene position: 614324-615364 (Clockwise)

Preceding gene: 225686430

Following gene: 225686433

Centisome position: 51.82

GC content: 58.31

Gene sequence:

>1041_bases
ATGGCGACAGAACAGACGATCAAGGTTTTCGACGGTCATAATGATGTATTGCTGCGCCTGTGGTCGTCAAACCAGCCCGA
ACCCGAAAATCGCTTCCTTGAAGGCGAAAGCAGCGGGCATATCGACTTGCCCCGTGCACGTAAGGGCGGACTGGGTGGCG
GTCTCTGTGCGGTCTACGTCCCCTCACCTTCGCACGATCTTGATGCGGACGGCAACCTGCCGACGCCAAGCCAGCAGGAT
ACCCTGAAGACAACGCTCGCCATGTCGGCCATCCTCCAGAACATCGAGCGCAAATCCGAAGGCCAGGTTCGCATTTGCCG
CACTGCGGCCGATATTCGCGATGCCTTCGCCAAAGACATCTTCGCCTCGGTCTATCATATCGAGGGCGTGGAAGCCTTCG
ATGCCGATCTCGACGCGCTTTATGTGCTTCATGCGGCGGGCCTGAGGTCACTTGGGCCCGTCTGGAGCCGCCCGAATATC
TTTGCCCATGGCATTCCGTTCCGCTTTCCGTCATCGCCCGATATCGGACCGGGCCTCACCGACCATGGCAAGGCCCTTAT
CCGCGCCTGCAATGAATTGAAGGTGATGATCGACCTTTCGCATATGAACGAAAAAGGCTTCTGGGACATTGCCGCCTTGT
CCGATGCACCGCTGGTTGCCTCACACTCCAATGCCCATGTGCTTTGCCAGCAAAGCCGCAACCTCACCGACAGGCAGCTT
GACGCCATCCGCGACACCGGCGGTCTGGTGGGGCTCAACTTCGGCGTTTCATTCCTGCGCGAAGACGGCAAGCACGATCC
CGATACGAAGCTTGAGGAACTGGTGCGCCATGCGGATTATATCGTGGGCCGCATCGGCATCGATCATGTGGCATTCGGCT
CGGATTTCGACGGCACCATCATATCCTCCACCTTGCGCGATGTGGCCGATCTACAGCTTGTGATCGAAACCTTCCGCAAG
CATGGCTATGACGATGCCTCCCTCGTCAAGCTGGCGCATGGAAACTGGATTGACGTGCTGGAACGCACCTGGGGGAAGTG
A

Upstream 100 bases:

>100_bases
ACCTGTTTGCAATTTGCCTTTTGCGGGTTCACTAACACCCCATCACCCTTCCGGGGAAGGCTCACTTCGCCCGAAAATTG
AACTGTAAAAGGCTTCCAAA

Downstream 100 bases:

>100_bases
CCAGCCTTCTTCAAGAAAGCCTGCCTGACACGCATCGCGCGTGAGCGGTTACGCGCGGGTGATGTAGCGAGCAACTTGCG
GGGGAATCAGAAGGCACGCG

Product: dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MATEQTIKVFDGHNDVLLRLWSSNQPEPENRFLEGESSGHIDLPRARKGGLGGGLCAVYVPSPSHDLDADGNLPTPSQQD
TLKTTLAMSAILQNIERKSEGQVRICRTAADIRDAFAKDIFASVYHIEGVEAFDADLDALYVLHAAGLRSLGPVWSRPNI
FAHGIPFRFPSSPDIGPGLTDHGKALIRACNELKVMIDLSHMNEKGFWDIAALSDAPLVASHSNAHVLCQQSRNLTDRQL
DAIRDTGGLVGLNFGVSFLREDGKHDPDTKLEELVRHADYIVGRIGIDHVAFGSDFDGTIISSTLRDVADLQLVIETFRK
HGYDDASLVKLAHGNWIDVLERTWGK

Sequences:

>Translated_346_residues
MATEQTIKVFDGHNDVLLRLWSSNQPEPENRFLEGESSGHIDLPRARKGGLGGGLCAVYVPSPSHDLDADGNLPTPSQQD
TLKTTLAMSAILQNIERKSEGQVRICRTAADIRDAFAKDIFASVYHIEGVEAFDADLDALYVLHAAGLRSLGPVWSRPNI
FAHGIPFRFPSSPDIGPGLTDHGKALIRACNELKVMIDLSHMNEKGFWDIAALSDAPLVASHSNAHVLCQQSRNLTDRQL
DAIRDTGGLVGLNFGVSFLREDGKHDPDTKLEELVRHADYIVGRIGIDHVAFGSDFDGTIISSTLRDVADLQLVIETFRK
HGYDDASLVKLAHGNWIDVLERTWGK
>Mature_345_residues
ATEQTIKVFDGHNDVLLRLWSSNQPEPENRFLEGESSGHIDLPRARKGGLGGGLCAVYVPSPSHDLDADGNLPTPSQQDT
LKTTLAMSAILQNIERKSEGQVRICRTAADIRDAFAKDIFASVYHIEGVEAFDADLDALYVLHAAGLRSLGPVWSRPNIF
AHGIPFRFPSSPDIGPGLTDHGKALIRACNELKVMIDLSHMNEKGFWDIAALSDAPLVASHSNAHVLCQQSRNLTDRQLD
AIRDTGGLVGLNFGVSFLREDGKHDPDTKLEELVRHADYIVGRIGIDHVAFGSDFDGTIISSTLRDVADLQLVIETFRKH
GYDDASLVKLAHGNWIDVLERTWGK

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=336, Percent_Identity=27.3809523809524, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI4758190, Length=336, Percent_Identity=27.3809523809524, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI11641269, Length=335, Percent_Identity=25.6716417910448, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI193211608, Length=346, Percent_Identity=24.5664739884393, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI193211610, Length=346, Percent_Identity=24.5664739884393, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221475880, Length=347, Percent_Identity=29.1066282420749, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281362638, Length=352, Percent_Identity=28.4090909090909, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281362636, Length=352, Percent_Identity=28.4090909090909, Blast_Score=114, Evalue=8e-26,
Organism=Drosophila melanogaster, GI161083233, Length=304, Percent_Identity=26.6447368421053, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 37946; Mature: 37815

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEQTIKVFDGHNDVLLRLWSSNQPEPENRFLEGESSGHIDLPRARKGGLGGGLCAVYV
CCCCCEEEEECCCCEEEEEEECCCCCCHHHCEECCCCCCCEECCCCCCCCCCCCEEEEEE
PSPSHDLDADGNLPTPSQQDTLKTTLAMSAILQNIERKSEGQVRICRTAADIRDAFAKDI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHH
FASVYHIEGVEAFDADLDALYVLHAAGLRSLGPVWSRPNIFAHGIPFRFPSSPDIGPGLT
HHHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
DHGKALIRACNELKVMIDLSHMNEKGFWDIAALSDAPLVASHSNAHVLCQQSRNLTDRQL
HHHHHHHHHHHHEEEEEEEECCCCCCCEEEEECCCCCEEECCCCCEEEECCCCCCCHHHH
DAIRDTGGLVGLNFGVSFLREDGKHDPDTKLEELVRHADYIVGRIGIDHVAFGSDFDGTI
HHHHHCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHH
ISSTLRDVADLQLVIETFRKHGYDDASLVKLAHGNWIDVLERTWGK
HHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCHHHHHHHHCCC
>Mature Secondary Structure 
ATEQTIKVFDGHNDVLLRLWSSNQPEPENRFLEGESSGHIDLPRARKGGLGGGLCAVYV
CCCCEEEEECCCCEEEEEEECCCCCCHHHCEECCCCCCCEECCCCCCCCCCCCEEEEEE
PSPSHDLDADGNLPTPSQQDTLKTTLAMSAILQNIERKSEGQVRICRTAADIRDAFAKDI
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHH
FASVYHIEGVEAFDADLDALYVLHAAGLRSLGPVWSRPNIFAHGIPFRFPSSPDIGPGLT
HHHHHHHCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCCC
DHGKALIRACNELKVMIDLSHMNEKGFWDIAALSDAPLVASHSNAHVLCQQSRNLTDRQL
HHHHHHHHHHHHEEEEEEEECCCCCCCEEEEECCCCCEEECCCCCEEEECCCCCCCHHHH
DAIRDTGGLVGLNFGVSFLREDGKHDPDTKLEELVRHADYIVGRIGIDHVAFGSDFDGTI
HHHHHCCCEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCCCHH
ISSTLRDVADLQLVIETFRKHGYDDASLVKLAHGNWIDVLERTWGK
HHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]