| Definition | Brucella melitensis ATCC 23457 chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_012442 |
| Length | 1,185,518 |
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The map label for this gene is livG [H]
Identifier: 225686429
GI number: 225686429
Start: 610957
End: 611706
Strand: Direct
Name: livG [H]
Synonym: BMEA_B0624
Alternate gene names: 225686429
Gene position: 610957-611706 (Clockwise)
Preceding gene: 225686428
Following gene: 225686430
Centisome position: 51.54
GC content: 59.73
Gene sequence:
>750_bases ATGAGCACCGTGTTTGAAGTATCGAAGCTGCGCAAGAATTTCGGTGGGCTTGCCGTTACCAACGACGTTTCGCTCAGCAT GGCAAAGGGCGACCGCGTTGCCCTGATCGGCCCCAACGGGGCGGGCAAGACCACATTCGTCAATCTTGTGACGGGCAATC TTGCCGCTACCTCCGGCACGGTGACACTCGGTGGTGAGAATGTTTCCAAGCTCAATGCCATGCAGCGCGTGCGCCGCGGC CTTGTGCGTTCGTTCCAGGTTACGCGCCTTTTCTTCGACATGACGCCGGAAGAGCATGTCGCGCTTGCCATCCTCCAGCG CGAGGGAAAAACAGGCCGCATTCTCGGCAATTATCGCAGGATGCCGCAAGTCATGGATGAAGCGCGCGATATTCTCCATA TGCTCGGGCTGTTGCCGCTCGCGCAATTGCGCGTGAGCGAGATCGCCTACGGGCAGCAGCACCTTCTGGAAATCGCGCTG GCGCTGGCATTGCGCCCGAAAGTGCTTCTGCTGGACGAACCCGCCGCCGGTGTGCCGCAAAGCGATACGGGCCGTATCGA AGAGGCTCTGGACCGGCTACCCCCAGACCTTGCCGTTCTTATGATCGAACATGACATGGACCTCGTCTTCCGTTTTGCAA AACGTGTCGTGGTGCTTGCCGCCGGAACGGTGATTTTCGACGGTCTGCCGCAGGCTGTGGTGCAGGATGCCCGCGTCCGC GAAGCCTATCTCGGGAGTTATGCGCAATGA
Upstream 100 bases:
>100_bases TCACCATGGTCGGCGCGCTCCTCATTGCCGTGGTGCTCTTCGCCCCGCGCGGCCTTTACGGAACCCTCGCCTATTATTTT GAAAAGAAGGCGCGCCGCAA
Downstream 100 bases:
>100_bases GTGCCGCCTCGCTTGAAATCCGCAATCTCTCCTCCGGCTACGGTCCCACGCGTGTTATCGAGGATGTATCCTTCAAGGCC GAACCCGGCTCGCGACTTGC
Product: ABC transporter-like protein
Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]
Alternate protein names: LIV-I protein G [H]
Number of amino acids: Translated: 249; Mature: 248
Protein sequence:
>249_residues MSTVFEVSKLRKNFGGLAVTNDVSLSMAKGDRVALIGPNGAGKTTFVNLVTGNLAATSGTVTLGGENVSKLNAMQRVRRG LVRSFQVTRLFFDMTPEEHVALAILQREGKTGRILGNYRRMPQVMDEARDILHMLGLLPLAQLRVSEIAYGQQHLLEIAL ALALRPKVLLLDEPAAGVPQSDTGRIEEALDRLPPDLAVLMIEHDMDLVFRFAKRVVVLAAGTVIFDGLPQAVVQDARVR EAYLGSYAQ
Sequences:
>Translated_249_residues MSTVFEVSKLRKNFGGLAVTNDVSLSMAKGDRVALIGPNGAGKTTFVNLVTGNLAATSGTVTLGGENVSKLNAMQRVRRG LVRSFQVTRLFFDMTPEEHVALAILQREGKTGRILGNYRRMPQVMDEARDILHMLGLLPLAQLRVSEIAYGQQHLLEIAL ALALRPKVLLLDEPAAGVPQSDTGRIEEALDRLPPDLAVLMIEHDMDLVFRFAKRVVVLAAGTVIFDGLPQAVVQDARVR EAYLGSYAQ >Mature_248_residues STVFEVSKLRKNFGGLAVTNDVSLSMAKGDRVALIGPNGAGKTTFVNLVTGNLAATSGTVTLGGENVSKLNAMQRVRRGL VRSFQVTRLFFDMTPEEHVALAILQREGKTGRILGNYRRMPQVMDEARDILHMLGLLPLAQLRVSEIAYGQQHLLEIALA LALRPKVLLLDEPAAGVPQSDTGRIEEALDRLPPDLAVLMIEHDMDLVFRFAKRVVVLAAGTVIFDGLPQAVVQDARVRE AYLGSYAQ
Specific function: Component of the leucine-specific transport system [H]
COG id: COG0411
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI27881501, Length=219, Percent_Identity=26.4840182648402, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI30795238, Length=219, Percent_Identity=26.4840182648402, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI116734710, Length=222, Percent_Identity=28.8288288288288, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI105990541, Length=215, Percent_Identity=28.3720930232558, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI47078218, Length=233, Percent_Identity=27.4678111587983, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI45446740, Length=233, Percent_Identity=27.4678111587983, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI21536376, Length=213, Percent_Identity=30.5164319248826, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI171184400, Length=216, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI153792144, Length=212, Percent_Identity=24.5283018867925, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI150417984, Length=233, Percent_Identity=28.3261802575107, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI31657092, Length=225, Percent_Identity=26.6666666666667, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI27262624, Length=216, Percent_Identity=24.0740740740741, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI27262626, Length=216, Percent_Identity=24.0740740740741, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI27477115, Length=224, Percent_Identity=24.5535714285714, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI27436953, Length=197, Percent_Identity=25.8883248730964, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1789864, Length=251, Percent_Identity=38.6454183266932, Blast_Score=155, Evalue=3e-39, Organism=Escherichia coli, GI1788761, Length=239, Percent_Identity=30.9623430962343, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI87082268, Length=240, Percent_Identity=28.3333333333333, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1789593, Length=242, Percent_Identity=31.8181818181818, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1787029, Length=237, Percent_Identity=27.8481012658228, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1787370, Length=240, Percent_Identity=27.5, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI87081709, Length=246, Percent_Identity=29.2682926829268, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI87081791, Length=255, Percent_Identity=26.2745098039216, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI1790739, Length=257, Percent_Identity=30.7392996108949, Blast_Score=88, Evalue=5e-19, Organism=Escherichia coli, GI1790162, Length=233, Percent_Identity=28.3261802575107, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789672, Length=237, Percent_Identity=25.3164556962025, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1788450, Length=230, Percent_Identity=26.5217391304348, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1788210, Length=216, Percent_Identity=27.7777777777778, Blast_Score=82, Evalue=2e-17, Organism=Escherichia coli, GI1790544, Length=243, Percent_Identity=30.8641975308642, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI1786563, Length=221, Percent_Identity=28.0542986425339, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1788225, Length=239, Percent_Identity=25.9414225941423, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI48995001, Length=226, Percent_Identity=25.6637168141593, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1788897, Length=220, Percent_Identity=27.7272727272727, Blast_Score=77, Evalue=8e-16, Organism=Escherichia coli, GI87081834, Length=205, Percent_Identity=29.7560975609756, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1789991, Length=234, Percent_Identity=25.6410256410256, Blast_Score=76, Evalue=3e-15, Organism=Escherichia coli, GI1789891, Length=213, Percent_Identity=31.4553990610329, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1790525, Length=230, Percent_Identity=25.2173913043478, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1786253, Length=231, Percent_Identity=27.7056277056277, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1789586, Length=236, Percent_Identity=29.2372881355932, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787089, Length=221, Percent_Identity=25.7918552036199, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1788472, Length=229, Percent_Identity=24.4541484716157, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI2367384, Length=215, Percent_Identity=30.6976744186047, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1790190, Length=207, Percent_Identity=27.536231884058, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1787712, Length=226, Percent_Identity=25.2212389380531, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1790467, Length=232, Percent_Identity=27.5862068965517, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI87081782, Length=230, Percent_Identity=26.5217391304348, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1786319, Length=181, Percent_Identity=32.0441988950276, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1786872, Length=252, Percent_Identity=28.1746031746032, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1789873, Length=214, Percent_Identity=28.0373831775701, Blast_Score=71, Evalue=5e-14, Organism=Escherichia coli, GI1786803, Length=238, Percent_Identity=24.3697478991597, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1787792, Length=218, Percent_Identity=23.394495412844, Blast_Score=70, Evalue=9e-14, Organism=Escherichia coli, GI1786398, Length=209, Percent_Identity=30.622009569378, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI87082267, Length=224, Percent_Identity=26.7857142857143, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI145693107, Length=222, Percent_Identity=28.8288288288288, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1789032, Length=221, Percent_Identity=25.7918552036199, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1788506, Length=213, Percent_Identity=26.7605633802817, Blast_Score=68, Evalue=7e-13, Organism=Escherichia coli, GI1786345, Length=243, Percent_Identity=23.4567901234568, Blast_Score=67, Evalue=8e-13, Organism=Escherichia coli, GI1787105, Length=236, Percent_Identity=25.8474576271186, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1788165, Length=238, Percent_Identity=27.3109243697479, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787500, Length=232, Percent_Identity=26.7241379310345, Blast_Score=67, Evalue=2e-12, Organism=Escherichia coli, GI48994943, Length=251, Percent_Identity=27.0916334661355, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1787759, Length=263, Percent_Identity=25.8555133079848, Blast_Score=64, Evalue=7e-12, Organism=Escherichia coli, GI1789963, Length=252, Percent_Identity=26.1904761904762, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1789751, Length=208, Percent_Identity=26.4423076923077, Blast_Score=61, Evalue=6e-11, Organism=Escherichia coli, GI1787041, Length=213, Percent_Identity=27.6995305164319, Blast_Score=61, Evalue=6e-11, Organism=Escherichia coli, GI48994883, Length=239, Percent_Identity=25.5230125523013, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI71983516, Length=227, Percent_Identity=28.6343612334802, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71983510, Length=227, Percent_Identity=28.6343612334802, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71983523, Length=227, Percent_Identity=28.6343612334802, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17510237, Length=235, Percent_Identity=24.6808510638298, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI193211015, Length=225, Percent_Identity=26.2222222222222, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI193211017, Length=234, Percent_Identity=26.4957264957265, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193209708, Length=226, Percent_Identity=24.3362831858407, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI212646699, Length=225, Percent_Identity=25.3333333333333, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17541710, Length=213, Percent_Identity=28.6384976525822, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17565586, Length=218, Percent_Identity=25.6880733944954, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI221512771, Length=223, Percent_Identity=26.457399103139, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24666092, Length=219, Percent_Identity=26.9406392694064, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24643674, Length=224, Percent_Identity=26.3392857142857, Blast_Score=78, Evalue=7e-15, Organism=Drosophila melanogaster, GI116007184, Length=226, Percent_Identity=26.5486725663717, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI221500365, Length=226, Percent_Identity=26.5486725663717, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI28574533, Length=229, Percent_Identity=27.0742358078603, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24648314, Length=223, Percent_Identity=25.1121076233184, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI28574150, Length=217, Percent_Identity=26.7281105990783, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI116007328, Length=217, Percent_Identity=26.7281105990783, Blast_Score=70, Evalue=2e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 27130; Mature: 26999
Theoretical pI: Translated: 9.47; Mature: 9.47
Prosite motif: PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.6 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.2 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTVFEVSKLRKNFGGLAVTNDVSLSMAKGDRVALIGPNGAGKTTFVNLVTGNLAATSGT CCHHHHHHHHHHHCCCEEEECCCEEEEECCCEEEEECCCCCCCEEEEEEEECCEEECCCE VTLGGENVSKLNAMQRVRRGLVRSFQVTRLFFDMTPEEHVALAILQREGKTGRILGNYRR EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHEECCCCCCCCCHHHHHH MPQVMDEARDILHMLGLLPLAQLRVSEIAYGQQHLLEIALALALRPKVLLLDEPAAGVPQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC SDTGRIEEALDRLPPDLAVLMIEHDMDLVFRFAKRVVVLAAGTVIFDGLPQAVVQDARVR CCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH EAYLGSYAQ HHHHCCCCC >Mature Secondary Structure STVFEVSKLRKNFGGLAVTNDVSLSMAKGDRVALIGPNGAGKTTFVNLVTGNLAATSGT CHHHHHHHHHHHCCCEEEECCCEEEEECCCEEEEECCCCCCCEEEEEEEECCEEECCCE VTLGGENVSKLNAMQRVRRGLVRSFQVTRLFFDMTPEEHVALAILQREGKTGRILGNYRR EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEHEECCCCCCCCCHHHHHH MPQVMDEARDILHMLGLLPLAQLRVSEIAYGQQHLLEIALALALRPKVLLLDEPAAGVPQ HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCC SDTGRIEEALDRLPPDLAVLMIEHDMDLVFRFAKRVVVLAAGTVIFDGLPQAVVQDARVR CCCCHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH EAYLGSYAQ HHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]
Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]