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The map label for this gene is rnr [H]

Identifier: 225686391

GI number: 225686391

Start: 571995

End: 574346

Strand: Direct

Name: rnr [H]

Synonym: BMEA_B0580

Alternate gene names: 225686391

Gene position: 571995-574346 (Clockwise)

Preceding gene: 225686390

Following gene: 225686392

Centisome position: 48.25

GC content: 60.37

Gene sequence:

>2352_bases
TTGGCACGCCGTTTTTCCAAATCCGATACCGTACGATCCGCACGGACCGAGCGGCGTGCAGCCACAGCCCAATCGAAAGA
TTCCGCAGCCTTTTTGCCGACACGGGAAGAGGTCCTCAAATATATCGAGGAAAATCCCGATCGCGCGGGCAAGCGGGAAC
TCGCCAAGGCTTTCAACATCAAGGGCGATGCACGGGTCTATCTGAAAGACCTGTTGCGTGAGCTTGCCGATGAAGGTCTC
GTCGAAAAGCGCGCGCGCAAGCTTTCGCGTCCCGGCTCGCTGCCATCGGTTGCGGTTCTCGATATTACGGGCCGGGATGA
GGATGGAGGCCTGCTTGCCCGCCCGGCTGAATGGGATGAGGCGAGCCACGGCAAGCCGCCAGTGGTCCTGCTGCGGCGAA
CCCGGCTTAACAAGACGTCAGAAAGTGGCCCTGTCGTCGGCGTTGGCGACCGCGTTCTGGCGAAAATCTTCCGCAATGAA
GATCACGCAGGGCCGGATTTTTCCGCCCGCGTGATGAAGCGGCTGGAACATCACGCCAATGCCGTTCTGGGCGTGGTGCG
CAAACTTGGCAATGGCGAATGGCGGCTGGAGCCGGTCAATCGCAAACAGGGCGAAGTGCAGCTTGATCCCGCCATGCTGG
AAAATGCCGAAAGCGGCGATCTGGTGGAAGTAGAACTGCTTTCCGCGCGCCGTTACGGCCTGCCGCGCGGCAAGGTCCGT
CAGGTGGTTGGCTCCATCGATAGTGAAAAGGCGCTGTCGATGATCGCCATTCACGAACATGAAATCCCGCATGTTTTTCC
TGACGAAGTGCTGCGCGAGGCTGAAACCGCAGGCCCTGCCACGCTGGAAGGCCGCGAAGACTGGCGCGAAATCCCGCTCA
TCACCATCGATCCGGCCGACGCCAAGGACCATGACGATGCGGTCTATGCCGAACCGGATACGGACCCGGAAAATCCCGGC
GGGCAAGTCGTCATCGTCGCCATCGCCGATGTCGCCGCCTATGTGCGGCCCGGCTCAGCCCTTGATCGCGAAGCGCAGAA
ACGCGGCAATTCCGTCTATTTTCCCGACCGCGTTGTACCGATGCTGCCCGAACGCATCTCCAATGATCTTTGCTCCCTGC
GCGAGATGGAAGACCGGCCGGCGCTGGCGGTCCGTATGATTTTCAGTGCCGACGGGCGCAAGAAATCACACAAGTTCCAC
CGCATCATGATGCGCTCGGCCGCCAAGGTTGCCTATGGCCAGGCGCAAGCCGCCATAGACGGCGCCCCCGATGACAAGAC
CGGGCCGATTCTTGATACCGTTCTAAAGCCGCTCTGGAACGCCTATGCGGTTCTCAAGCGCGGGCGTGACGCACGCGAGC
CGCTGGAACTCGATCTGCCGGGAAAGAAAATCCTACTGACGCCGGAAGGCAAGGTGGACAAAGTCATCGTGCCGGAACGC
CTCGATGCGCATAAGCTCATCGAAGAATTCATGATTCAGGCCAATGTGTCTGCCGCCGAAACGCTCGAAGGACGGCACCA
GCCGCTTATTTTCCGCATTCACGGTGAACCGGCGCTGGCCAAGCAGGAAACCCTGCGTGAGTTCCTGCGTACGCTGGATC
TCAATCTTGCCAAGGGCGCGCAACTGCAGCCCGCGCAGTTCAATCGCATTCTGGCGGCGGTCGATGGCACAGACCATCAG
GAACTCGTCAATCAGGTCGTGCTGCGCACCCAGAGCCAGGCCGAATACAGCCCCGACAATATCGGCCATTTTGGCCTGCA
TCTGCGCCGTTATGCGCATTTCACCTCACCAATCCGCCGTTATGCTGATCTGATCGTGCACCGCGCGCTCATCAAGGCGC
TGGGGCTTGGCACGGACGGGTTGACGAGCGCGGAAGAAGCGCAGCTTGAAGAGATTTCGGCCCTGATTTCGGCCACCGAA
CGCCGCGCCATGCTGGCTGAGCGTGAAACCGTGGATCGGCTGATCGCGCATTTCCTCGCCTCGCATCTCGGCGACGAATA
TGAGGGGCGCGTTACCGGCGTCACGCGCGCCGGTCTGTTCGTCAATCTTGCGACATATGGCGCAGACGGACTGGTGCCCA
TTTCAACTTTGGGCGATGAATATTATCTATATGACGAAGCAAACCACGCAATCGCGGGCGAACGAAGCGGCAGGGGCTTT
CGTCTGGGCGATACGGTAACGGTGAGGCTTGTGGAAGCACTCCCCGTTGCGGGTGCGCTTCGTTTTGAAATGGTTTCCGA
ACCGCACCCCTTGCCCATGTCGACGCGCTCGCATCATAAGGCGAGCCGGGCAATGCGGGGCCGGAAAGGCAAGCCGGCGG
GTATTCCCCGCCACAAGAGGAGAGGTCACTGA

Upstream 100 bases:

>100_bases
GGCGGCAAGTTCTGAAAAGAAGACAACCGCGAAAAAGACCGCTACAAAAAAAGCCCCGGCCAAAGCCAAGAGCAAGGCCA
AGGCGGCAGAGGAGTAACAA

Downstream 100 bases:

>100_bases
TGAGCACGCTAGAGGCCAATTCCGAGCAGAACATACAGGTTTTCGGCGGCAAAAACCCGAAAGCCATCCTGCCCAAGCGC
CCGGTGGGGGAAGCCCTGTG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MARRFSKSDTVRSARTERRAATAQSKDSAAFLPTREEVLKYIEENPDRAGKRELAKAFNIKGDARVYLKDLLRELADEGL
VEKRARKLSRPGSLPSVAVLDITGRDEDGGLLARPAEWDEASHGKPPVVLLRRTRLNKTSESGPVVGVGDRVLAKIFRNE
DHAGPDFSARVMKRLEHHANAVLGVVRKLGNGEWRLEPVNRKQGEVQLDPAMLENAESGDLVEVELLSARRYGLPRGKVR
QVVGSIDSEKALSMIAIHEHEIPHVFPDEVLREAETAGPATLEGREDWREIPLITIDPADAKDHDDAVYAEPDTDPENPG
GQVVIVAIADVAAYVRPGSALDREAQKRGNSVYFPDRVVPMLPERISNDLCSLREMEDRPALAVRMIFSADGRKKSHKFH
RIMMRSAAKVAYGQAQAAIDGAPDDKTGPILDTVLKPLWNAYAVLKRGRDAREPLELDLPGKKILLTPEGKVDKVIVPER
LDAHKLIEEFMIQANVSAAETLEGRHQPLIFRIHGEPALAKQETLREFLRTLDLNLAKGAQLQPAQFNRILAAVDGTDHQ
ELVNQVVLRTQSQAEYSPDNIGHFGLHLRRYAHFTSPIRRYADLIVHRALIKALGLGTDGLTSAEEAQLEEISALISATE
RRAMLAERETVDRLIAHFLASHLGDEYEGRVTGVTRAGLFVNLATYGADGLVPISTLGDEYYLYDEANHAIAGERSGRGF
RLGDTVTVRLVEALPVAGALRFEMVSEPHPLPMSTRSHHKASRAMRGRKGKPAGIPRHKRRGH

Sequences:

>Translated_783_residues
MARRFSKSDTVRSARTERRAATAQSKDSAAFLPTREEVLKYIEENPDRAGKRELAKAFNIKGDARVYLKDLLRELADEGL
VEKRARKLSRPGSLPSVAVLDITGRDEDGGLLARPAEWDEASHGKPPVVLLRRTRLNKTSESGPVVGVGDRVLAKIFRNE
DHAGPDFSARVMKRLEHHANAVLGVVRKLGNGEWRLEPVNRKQGEVQLDPAMLENAESGDLVEVELLSARRYGLPRGKVR
QVVGSIDSEKALSMIAIHEHEIPHVFPDEVLREAETAGPATLEGREDWREIPLITIDPADAKDHDDAVYAEPDTDPENPG
GQVVIVAIADVAAYVRPGSALDREAQKRGNSVYFPDRVVPMLPERISNDLCSLREMEDRPALAVRMIFSADGRKKSHKFH
RIMMRSAAKVAYGQAQAAIDGAPDDKTGPILDTVLKPLWNAYAVLKRGRDAREPLELDLPGKKILLTPEGKVDKVIVPER
LDAHKLIEEFMIQANVSAAETLEGRHQPLIFRIHGEPALAKQETLREFLRTLDLNLAKGAQLQPAQFNRILAAVDGTDHQ
ELVNQVVLRTQSQAEYSPDNIGHFGLHLRRYAHFTSPIRRYADLIVHRALIKALGLGTDGLTSAEEAQLEEISALISATE
RRAMLAERETVDRLIAHFLASHLGDEYEGRVTGVTRAGLFVNLATYGADGLVPISTLGDEYYLYDEANHAIAGERSGRGF
RLGDTVTVRLVEALPVAGALRFEMVSEPHPLPMSTRSHHKASRAMRGRKGKPAGIPRHKRRGH
>Mature_782_residues
ARRFSKSDTVRSARTERRAATAQSKDSAAFLPTREEVLKYIEENPDRAGKRELAKAFNIKGDARVYLKDLLRELADEGLV
EKRARKLSRPGSLPSVAVLDITGRDEDGGLLARPAEWDEASHGKPPVVLLRRTRLNKTSESGPVVGVGDRVLAKIFRNED
HAGPDFSARVMKRLEHHANAVLGVVRKLGNGEWRLEPVNRKQGEVQLDPAMLENAESGDLVEVELLSARRYGLPRGKVRQ
VVGSIDSEKALSMIAIHEHEIPHVFPDEVLREAETAGPATLEGREDWREIPLITIDPADAKDHDDAVYAEPDTDPENPGG
QVVIVAIADVAAYVRPGSALDREAQKRGNSVYFPDRVVPMLPERISNDLCSLREMEDRPALAVRMIFSADGRKKSHKFHR
IMMRSAAKVAYGQAQAAIDGAPDDKTGPILDTVLKPLWNAYAVLKRGRDAREPLELDLPGKKILLTPEGKVDKVIVPERL
DAHKLIEEFMIQANVSAAETLEGRHQPLIFRIHGEPALAKQETLREFLRTLDLNLAKGAQLQPAQFNRILAAVDGTDHQE
LVNQVVLRTQSQAEYSPDNIGHFGLHLRRYAHFTSPIRRYADLIVHRALIKALGLGTDGLTSAEEAQLEEISALISATER
RAMLAERETVDRLIAHFLASHLGDEYEGRVTGVTRAGLFVNLATYGADGLVPISTLGDEYYLYDEANHAIAGERSGRGFR
LGDTVTVRLVEALPVAGALRFEMVSEPHPLPMSTRSHHKASRAMRGRKGKPAGIPRHKRRGH

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=477, Percent_Identity=28.5115303983228, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI190014625, Length=477, Percent_Identity=28.5115303983228, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI134288890, Length=366, Percent_Identity=32.2404371584699, Blast_Score=150, Evalue=6e-36,
Organism=Homo sapiens, GI219521928, Length=582, Percent_Identity=26.1168384879725, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI19115966, Length=581, Percent_Identity=25.6454388984509, Blast_Score=120, Evalue=4e-27,
Organism=Escherichia coli, GI87082383, Length=722, Percent_Identity=35.0415512465374, Blast_Score=355, Evalue=8e-99,
Organism=Escherichia coli, GI1787542, Length=490, Percent_Identity=30.8163265306122, Blast_Score=168, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI212645896, Length=487, Percent_Identity=31.4168377823409, Blast_Score=182, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17553506, Length=477, Percent_Identity=29.769392033543, Blast_Score=154, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324552, Length=496, Percent_Identity=29.4354838709677, Blast_Score=170, Evalue=8e-43,
Organism=Saccharomyces cerevisiae, GI6320499, Length=294, Percent_Identity=25.1700680272109, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649634, Length=562, Percent_Identity=26.5124555160142, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI19922976, Length=362, Percent_Identity=29.2817679558011, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24654597, Length=362, Percent_Identity=29.2817679558011, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24654592, Length=362, Percent_Identity=29.2817679558011, Blast_Score=131, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 86680; Mature: 86549

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRFSKSDTVRSARTERRAATAQSKDSAAFLPTREEVLKYIEENPDRAGKRELAKAFNI
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCC
KGDARVYLKDLLRELADEGLVEKRARKLSRPGSLPSVAVLDITGRDEDGGLLARPAEWDE
CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEECCCCCCC
ASHGKPPVVLLRRTRLNKTSESGPVVGVGDRVLAKIFRNEDHAGPDFSARVMKRLEHHAN
CCCCCCCEEEEEEHHCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AVLGVVRKLGNGEWRLEPVNRKQGEVQLDPAMLENAESGDLVEVELLSARRYGLPRGKVR
HHHHHHHHHCCCCEEEEECCCCCCCEEECHHHHCCCCCCCEEEEEEHHHHHCCCCHHHHH
QVVGSIDSEKALSMIAIHEHEIPHVFPDEVLREAETAGPATLEGREDWREIPLITIDPAD
HHHHCCCCHHHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCEEEECCCC
AKDHDDAVYAEPDTDPENPGGQVVIVAIADVAAYVRPGSALDREAQKRGNSVYFPDRVVP
CCCCCCEEEECCCCCCCCCCCCEEEEEEEHHHHHHCCCHHHHHHHHHCCCCEECCCCHHH
MLPERISNDLCSLREMEDRPALAVRMIFSADGRKKSHKFHRIMMRSAAKVAYGQAQAAID
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCC
GAPDDKTGPILDTVLKPLWNAYAVLKRGRDAREPLELDLPGKKILLTPEGKVDKVIVPER
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEECCCCCCCEEECCCC
LDAHKLIEEFMIQANVSAAETLEGRHQPLIFRIHGEPALAKQETLREFLRTLDLNLAKGA
CCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
QLQPAQFNRILAAVDGTDHQELVNQVVLRTQSQAEYSPDNIGHFGLHLRRYAHFTSPIRR
CCCHHHHHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YADLIVHRALIKALGLGTDGLTSAEEAQLEEISALISATERRAMLAERETVDRLIAHFLA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHLGDEYEGRVTGVTRAGLFVNLATYGADGLVPISTLGDEYYLYDEANHAIAGERSGRGF
HHCCCCCCCEEEEEECCCEEEEEHHCCCCCCEEHHHCCCEEEEEECCCCCCCCCCCCCCE
RLGDTVTVRLVEALPVAGALRFEMVSEPHPLPMSTRSHHKASRAMRGRKGKPAGIPRHKR
ECCCHHEEHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
RGH
CCC
>Mature Secondary Structure 
ARRFSKSDTVRSARTERRAATAQSKDSAAFLPTREEVLKYIEENPDRAGKRELAKAFNI
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCC
KGDARVYLKDLLRELADEGLVEKRARKLSRPGSLPSVAVLDITGRDEDGGLLARPAEWDE
CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEECCCCCCC
ASHGKPPVVLLRRTRLNKTSESGPVVGVGDRVLAKIFRNEDHAGPDFSARVMKRLEHHAN
CCCCCCCEEEEEEHHCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
AVLGVVRKLGNGEWRLEPVNRKQGEVQLDPAMLENAESGDLVEVELLSARRYGLPRGKVR
HHHHHHHHHCCCCEEEEECCCCCCCEEECHHHHCCCCCCCEEEEEEHHHHHCCCCHHHHH
QVVGSIDSEKALSMIAIHEHEIPHVFPDEVLREAETAGPATLEGREDWREIPLITIDPAD
HHHHCCCCHHHHHHHEEECCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHCCEEEECCCC
AKDHDDAVYAEPDTDPENPGGQVVIVAIADVAAYVRPGSALDREAQKRGNSVYFPDRVVP
CCCCCCEEEECCCCCCCCCCCCEEEEEEEHHHHHHCCCHHHHHHHHHCCCCEECCCCHHH
MLPERISNDLCSLREMEDRPALAVRMIFSADGRKKSHKFHRIMMRSAAKVAYGQAQAAID
HHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCC
GAPDDKTGPILDTVLKPLWNAYAVLKRGRDAREPLELDLPGKKILLTPEGKVDKVIVPER
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCEEEECCCCCCCEEECCCC
LDAHKLIEEFMIQANVSAAETLEGRHQPLIFRIHGEPALAKQETLREFLRTLDLNLAKGA
CCHHHHHHHHHHHCCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
QLQPAQFNRILAAVDGTDHQELVNQVVLRTQSQAEYSPDNIGHFGLHLRRYAHFTSPIRR
CCCHHHHHHEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YADLIVHRALIKALGLGTDGLTSAEEAQLEEISALISATERRAMLAERETVDRLIAHFLA
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHLGDEYEGRVTGVTRAGLFVNLATYGADGLVPISTLGDEYYLYDEANHAIAGERSGRGF
HHCCCCCCCEEEEEECCCEEEEEHHCCCCCCEEHHHCCCEEEEEECCCCCCCCCCCCCCE
RLGDTVTVRLVEALPVAGALRFEMVSEPHPLPMSTRSHHKASRAMRGRKGKPAGIPRHKR
ECCCHHEEHHHHHCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
RGH
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]