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The map label for this gene is aidB [H]

Identifier: 225686384

GI number: 225686384

Start: 563004

End: 564659

Strand: Reverse

Name: aidB [H]

Synonym: BMEA_B0573

Alternate gene names: 225686384

Gene position: 564659-563004 (Counterclockwise)

Preceding gene: 225686389

Following gene: 225686382

Centisome position: 47.63

GC content: 61.11

Gene sequence:

>1656_bases
TTGAATCAAGCCAAACGGAACGAACCCTTGAAAACGCACGAAGTCACCAACCAGACGCCGCCGATCACCGGCACGAACGC
TTATCTGGGCGACCCGCTTCTCATGCAGATTGCGGCGCGTTTTCCAAAAGAGCTTCATACAGAACTGGAGCAGGCGGGCC
GTTTCGTACTTTCGGCCGAGGCGCAGGATTTGGCTCGTCTTGCCAACACCGAATTGCCGAAGCTGCGTACGCATGACCGG
CAGGGCCGCCGCATCGACCTTGTCGAATATCACCCGGCCTATCACGCGCTGATGCGCCGCTCCGTGGCGCAGGGGCTGCA
TTCGTCCATATGGGAAGACAATCCGCTGGAGAGTGGCCGCCGTCATCAGGCGCGTGCCGCCCGTTTTTATCTCACTGCGC
AGCTTGAGGCCGGGCACCTTTGCCCGCTCACCATGACGAGCGCCTCTCTGGCCGCACTCATGGCCTCGCCGGAGGTTTAC
AAGCAATGGTCTCCGGCAGTCCTGTCGCGCAAATATGATTTTTCGCAAAAGCCTGCCTTCCGCAAACAGGGTGTTACGCT
TGGCATGGGCATGACGGAAAAACAGGGCGGCACCGATGTTCGCGCCAACGCCACCCGTGCCGAACCTGCCATTGGCGGGG
CATGGCGGCTTACGGGCCATAAATGGTTCATGTCGGCGCCGATGTCAGATGCTTTTCTGACACTGGCGCAAACGAAGGAG
GGGCTTTCCTGTTTCCTTCTGCCGCGACTGGGCGAAAAGGGCGAGAGCAATGGCTTTTTCTTCCAGCGCCTGAAAGATAA
GCTCGGCAACAGATCCAATGCTTCCTCGGAAGTGGAATTTGACGGGGCTTTGGGCCAGATGATCGGCAGTCCGGGCGAGG
GCGTGAAGACGATCATGGATATGGTGACGTTGACGCGGCTTGATTGCGCGGTAGCTTCTGCCGGACTTATGCGCTCAGGG
CTGGCTGAGGCCGTTCACCACAGCCGCCACCGCCATGTGTTCGGCAAGCCTTTGGTCGAGCAGCCGCTGATGCAGCGCGT
TCTGGCCGATATGGCGCTGGACGTGGCGGGCGCCACGGCGCTTTCCATGCGTCTTGCCCGCGCCTTCGACATGGCGGCAA
GCGACCGGGCGGAAGCCGCTTTTGCGCGCTCCATGACGCCGGTGGTGAAATATTGGGTCTGCAAGATTGCGCCTGCGCTC
CTTTATGAAGCGATGGAGTGCCTTGGCGGCAACGGCTATATCGAAGATGGCAATCTGGCGCGGGCCTATCGTGAAGCGCC
GGTCAATGCGATATGGGAAGGTTCCGGCAATGTGATGGCGCTGGACGTGGCACGGGTGCTCTCGCGTGCGCCGGCACTTT
TCGATGGCGTGCTGGACTGGATCAGCGGACAATTGGGCCCGCGCGGGCAGGGCACGATCGACGTGCTGCGCGCCGCCCTT
CAACTGACCGAGACGGATCAGGGTGTGGCACGTCTTTTGACCGAGCAGCTTGCCTTCGCAGCCGCAGCCGCTGAACTGCG
CCAGCTTGGCGCGGACGATATTGCTGATGCCTTTATCGAAACCCGCCTCGGCGGCCTGTGGCGCACCACCTACGGGATGC
TGGATGCGCGCCACAATGCGATGCGTATCATCGACCAGCTCTATCCGGCGTCGTAA

Upstream 100 bases:

>100_bases
TTCAGGCGATTCACAAAGAAAAACCTGCGCCCTATGAACGACAAATTGAAAGGAGGATGGGAAAATTTTAGCAAATGCAG
TGCAAGAGACTTAATGTAAG

Downstream 100 bases:

>100_bases
TCGTTCCTGCGCATCATATGCAGCCGGTCGAGCGCGCCTTGCAGGATGAAGGCGGCAGCAGCGGAATCGATACGGTCGGC
CCGCTTGCCGCGCGAGACGT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MNQAKRNEPLKTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDR
QGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVY
KQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKE
GLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSG
LAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPAL
LYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAAL
QLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPAS

Sequences:

>Translated_551_residues
MNQAKRNEPLKTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDR
QGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVY
KQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKE
GLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSG
LAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPAL
LYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAAL
QLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPAS
>Mature_551_residues
MNQAKRNEPLKTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAEAQDLARLANTELPKLRTHDR
QGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGRRHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVY
KQWSPAVLSRKYDFSQKPAFRKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKE
GLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMDMVTLTRLDCAVASAGLMRSG
LAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATALSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPAL
LYEAMECLGGNGYIEDGNLARAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAAL
QLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNAMRIIDQLYPAS

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=269, Percent_Identity=30.4832713754647, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI226958412, Length=271, Percent_Identity=27.3062730627306, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI226958414, Length=271, Percent_Identity=27.3062730627306, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4557235, Length=270, Percent_Identity=27.4074074074074, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI76496475, Length=270, Percent_Identity=27.4074074074074, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4501859, Length=282, Percent_Identity=25.531914893617, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI4501857, Length=271, Percent_Identity=26.1992619926199, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI7656849, Length=265, Percent_Identity=27.5471698113208, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4557231, Length=268, Percent_Identity=26.865671641791, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI187960098, Length=268, Percent_Identity=26.865671641791, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI21361497, Length=273, Percent_Identity=25.6410256410256, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4503943, Length=277, Percent_Identity=27.0758122743682, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87082384, Length=515, Percent_Identity=44.6601941747573, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI87081958, Length=182, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI86563381, Length=452, Percent_Identity=35.1769911504425, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI86563383, Length=452, Percent_Identity=35.1769911504425, Blast_Score=211, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17538396, Length=270, Percent_Identity=29.2592592592593, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71985184, Length=269, Percent_Identity=26.7657992565056, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=284, Percent_Identity=24.6478873239437, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=266, Percent_Identity=22.9323308270677, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=270, Percent_Identity=23.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=269, Percent_Identity=22.3048327137546, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=221, Percent_Identity=27.6018099547511, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=269, Percent_Identity=23.0483271375465, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21356377, Length=263, Percent_Identity=28.8973384030418, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI281363737, Length=308, Percent_Identity=23.7012987012987, Blast_Score=89, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24646207, Length=393, Percent_Identity=25.4452926208651, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666513, Length=268, Percent_Identity=23.5074626865672, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24660351, Length=303, Percent_Identity=25.4125412541254, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355753, Length=273, Percent_Identity=26.7399267399267, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 60274; Mature: 60274

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQAKRNEPLKTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAE
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEECC
AQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGR
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
RHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAF
HHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHCCHHHHHCCCCCCCCCCH
RKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKE
HHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHCCC
GLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMD
CCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEECHHHHHHHCCCCHHHHHHHH
MVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHH
RAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAAL
HHHHHCCCCEEEECCCCEEEEHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
QLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
MRIIDQLYPAS
HHHHHHHCCCC
>Mature Secondary Structure
MNQAKRNEPLKTHEVTNQTPPITGTNAYLGDPLLMQIAARFPKELHTELEQAGRFVLSAE
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCEEEECC
AQDLARLANTELPKLRTHDRQGRRIDLVEYHPAYHALMRRSVAQGLHSSIWEDNPLESGR
HHHHHHHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
RHQARAARFYLTAQLEAGHLCPLTMTSASLAALMASPEVYKQWSPAVLSRKYDFSQKPAF
HHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHCCHHHHHCCCCCCCCCCH
RKQGVTLGMGMTEKQGGTDVRANATRAEPAIGGAWRLTGHKWFMSAPMSDAFLTLAQTKE
HHCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCCCCHHHHHHHHCCC
GLSCFLLPRLGEKGESNGFFFQRLKDKLGNRSNASSEVEFDGALGQMIGSPGEGVKTIMD
CCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEECHHHHHHHCCCCHHHHHHHH
MVTLTRLDCAVASAGLMRSGLAEAVHHSRHRHVFGKPLVEQPLMQRVLADMALDVAGATA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LSMRLARAFDMAASDRAEAAFARSMTPVVKYWVCKIAPALLYEAMECLGGNGYIEDGNLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHH
RAYREAPVNAIWEGSGNVMALDVARVLSRAPALFDGVLDWISGQLGPRGQGTIDVLRAAL
HHHHHCCCCEEEECCCCEEEEHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
QLTETDQGVARLLTEQLAFAAAAAELRQLGADDIADAFIETRLGGLWRTTYGMLDARHNA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
MRIIDQLYPAS
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]