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The map label for this gene is glmS [H]

Identifier: 225686368

GI number: 225686368

Start: 544068

End: 545891

Strand: Reverse

Name: glmS [H]

Synonym: BMEA_B0556

Alternate gene names: 225686368

Gene position: 545891-544068 (Counterclockwise)

Preceding gene: 225686369

Following gene: 225686366

Centisome position: 46.05

GC content: 58.44

Gene sequence:

>1824_bases
ATGTGCGGAATCATCGGCATTATCGGAAATGACGAGGTCGCTCCGCGTCTCGTGGACGCATTGAAGCGCCTTGAATATCG
CGGCTACGATTCCGCCGGCATTGCCACATTGCAGAATGGCAGGCTCGACCGCCGCCGCGCCGAAGGCAAACTCGTCAATC
TGGAAAAGCGTCTTGCGGGCGAGCCGCTTCCGGGCGTGATCGGCATCGGCCATACCCGTTGGGCAACCCATGGCAGGCCG
GTGGAGCACAATGCGCATCCGCATATCACCACACGTCTTGCCGTGGTTCACAATGGAATCATCGAAAATTTCGCCGAATT
GCGCGCCATGCTGGAAGCCGAAGGCCGCAAATTTGAAACGGAAACCGACACGGAAGCCGTCGCCCATCTGGTGACGCGCG
AACTGGAAAAGGGCAAGTCGCCGGTGGAAGCCGTGCGCGATTGCCTGCCGCATCTCAAAGGCGCTTTTGCACTCGCCTTC
CTGTTTGAGGGCGATGAAGAACTGCTGATCGGCGCACGCCAGGGGCCGCCGCTTGCGGTTGGCTATGGTGAAGGCGAAAT
GTTCCTCGGCTCCGATGCGATTGCGCTCGCACCTTTCACCGATACCATCTCCTATCTGGAAGATGGCGATTGGGCTGTGC
TGACCCGCAATGGCGTCAGCATCTATGACGAAAACAACAAGCCGGTTGAGCGCCCGGTCCAGAAGTCGCAGAACACCAAT
ATGCTGGTATCGAAGGGCAACCATCGCCACTTCATGCAGAAGGAAATGTTCGAGCAGCCGGAAGTCATTTCCCACACGCT
TGCCAATTATCTCGACTTCACGACGGGCAAGGTGCGCAAGGAAGCGATCGGTATCGATTTCAGCAAGGTCGATCGCCTGA
CGATCACCGCTTGCGGCACGGCCTATTATGCCGCAACGGTTGCGAAATACTGGTTTGAACAGATTGCGCGCCTGCCGGTC
GATAGCGATATCGCGTCGGAATTCCGCTACCGCGAAATGCCGCTCTCGAAGGATTCGCTGGCCATGTTCGTTTCGCAGTC
GGGCGAAACGGCGGATACACTTGCTTCGCTGCGCTATTGCAAGGCGCAGGGCCTGAAAATCGCCTCGGTGCTCAACGTGA
CCGGCTCCACCATCGCGCGTGAATCGGATGCAGTGTTCCCGACGCTCGCAGGCCCTGAAATCGGCGTTGCTTCCACCAAG
GCCTTCACCTGCCAGCTTTCGGCCATGGCCTCACTCGCTATTGCGGCGGCGCGTGCGCGTGGTGCAATCGACGAGGTTCG
CGAGCAGGAACTGGTGCACCAGCTTTCCGAAGCGCCGCGTTTCATCAATCAGGTTTTGAAGCTTGAAGACCAGATTGCTG
TCGTCTGCCATGACCTGTCGAAGGTCAATCATGTGCTATATCTCGGTCGCGGCACGTCCTTCCCGCTCGCCATGGAAGGC
GCGCTGAAGCTCAAGGAAATCTCCTATATCCACGCCGAAGGCTATGCGGCAGGTGAGTTGAAGCATGGGCCGATTGCGCT
CATCGATGAAACCATGCCGGTGATCGTCATCGCACCATCTGATCGTCTCTATGAGAAGACCGTGTCGAACATGCAGGAAG
TGGCTGCGCGCGGCGGGCGCATCATCCTCATCACCGACAAGAAGGGGGCAGAAAGCGCCAGCATCGACACGATGGCCACC
ATCGTTCTGCCCGAGGTGCCGGAATTCATCTCGCCGCTCGTCTATGCGCTGCCGATCCAGATGCTCGCCTATCACACGGC
AGTCCTTATGGGAACGGACGTGGACCAGCCGCGCAATCTGGCCAAGTCTGTTACTGTCGAGTAA

Upstream 100 bases:

>100_bases
AACGGATGGAGGCTTTTACGGCAACAAGTCCGGGTGCCGTAAAGCTTTCAAGCCTTTAAAGCCTGCAATAGGCCAGACTT
TCTATTTGGAGCATGCATTT

Downstream 100 bases:

>100_bases
TCAGAACAAAAGCGTTATGGCTCCTCCAATGCCTCATCCTGAGGAGGTGCGAAGCACCGTCTCGACGGGTAAGGCATTGG
TTCTCAATAGACTTATCGCA

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MCGIIGIIGNDEVAPRLVDALKRLEYRGYDSAGIATLQNGRLDRRRAEGKLVNLEKRLAGEPLPGVIGIGHTRWATHGRP
VEHNAHPHITTRLAVVHNGIIENFAELRAMLEAEGRKFETETDTEAVAHLVTRELEKGKSPVEAVRDCLPHLKGAFALAF
LFEGDEELLIGARQGPPLAVGYGEGEMFLGSDAIALAPFTDTISYLEDGDWAVLTRNGVSIYDENNKPVERPVQKSQNTN
MLVSKGNHRHFMQKEMFEQPEVISHTLANYLDFTTGKVRKEAIGIDFSKVDRLTITACGTAYYAATVAKYWFEQIARLPV
DSDIASEFRYREMPLSKDSLAMFVSQSGETADTLASLRYCKAQGLKIASVLNVTGSTIARESDAVFPTLAGPEIGVASTK
AFTCQLSAMASLAIAAARARGAIDEVREQELVHQLSEAPRFINQVLKLEDQIAVVCHDLSKVNHVLYLGRGTSFPLAMEG
ALKLKEISYIHAEGYAAGELKHGPIALIDETMPVIVIAPSDRLYEKTVSNMQEVAARGGRIILITDKKGAESASIDTMAT
IVLPEVPEFISPLVYALPIQMLAYHTAVLMGTDVDQPRNLAKSVTVE

Sequences:

>Translated_607_residues
MCGIIGIIGNDEVAPRLVDALKRLEYRGYDSAGIATLQNGRLDRRRAEGKLVNLEKRLAGEPLPGVIGIGHTRWATHGRP
VEHNAHPHITTRLAVVHNGIIENFAELRAMLEAEGRKFETETDTEAVAHLVTRELEKGKSPVEAVRDCLPHLKGAFALAF
LFEGDEELLIGARQGPPLAVGYGEGEMFLGSDAIALAPFTDTISYLEDGDWAVLTRNGVSIYDENNKPVERPVQKSQNTN
MLVSKGNHRHFMQKEMFEQPEVISHTLANYLDFTTGKVRKEAIGIDFSKVDRLTITACGTAYYAATVAKYWFEQIARLPV
DSDIASEFRYREMPLSKDSLAMFVSQSGETADTLASLRYCKAQGLKIASVLNVTGSTIARESDAVFPTLAGPEIGVASTK
AFTCQLSAMASLAIAAARARGAIDEVREQELVHQLSEAPRFINQVLKLEDQIAVVCHDLSKVNHVLYLGRGTSFPLAMEG
ALKLKEISYIHAEGYAAGELKHGPIALIDETMPVIVIAPSDRLYEKTVSNMQEVAARGGRIILITDKKGAESASIDTMAT
IVLPEVPEFISPLVYALPIQMLAYHTAVLMGTDVDQPRNLAKSVTVE
>Mature_607_residues
MCGIIGIIGNDEVAPRLVDALKRLEYRGYDSAGIATLQNGRLDRRRAEGKLVNLEKRLAGEPLPGVIGIGHTRWATHGRP
VEHNAHPHITTRLAVVHNGIIENFAELRAMLEAEGRKFETETDTEAVAHLVTRELEKGKSPVEAVRDCLPHLKGAFALAF
LFEGDEELLIGARQGPPLAVGYGEGEMFLGSDAIALAPFTDTISYLEDGDWAVLTRNGVSIYDENNKPVERPVQKSQNTN
MLVSKGNHRHFMQKEMFEQPEVISHTLANYLDFTTGKVRKEAIGIDFSKVDRLTITACGTAYYAATVAKYWFEQIARLPV
DSDIASEFRYREMPLSKDSLAMFVSQSGETADTLASLRYCKAQGLKIASVLNVTGSTIARESDAVFPTLAGPEIGVASTK
AFTCQLSAMASLAIAAARARGAIDEVREQELVHQLSEAPRFINQVLKLEDQIAVVCHDLSKVNHVLYLGRGTSFPLAMEG
ALKLKEISYIHAEGYAAGELKHGPIALIDETMPVIVIAPSDRLYEKTVSNMQEVAARGGRIILITDKKGAESASIDTMAT
IVLPEVPEFISPLVYALPIQMLAYHTAVLMGTDVDQPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI4826742, Length=688, Percent_Identity=37.7906976744186, Blast_Score=414, Evalue=1e-115,
Organism=Homo sapiens, GI205277386, Length=690, Percent_Identity=36.9565217391304, Blast_Score=410, Evalue=1e-114,
Organism=Escherichia coli, GI1790167, Length=613, Percent_Identity=49.2659053833605, Blast_Score=569, Evalue=1e-163,
Organism=Escherichia coli, GI1788651, Length=150, Percent_Identity=34, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17539970, Length=716, Percent_Identity=34.7765363128492, Blast_Score=390, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17532899, Length=432, Percent_Identity=38.1944444444444, Blast_Score=306, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17532897, Length=439, Percent_Identity=37.8132118451025, Blast_Score=306, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6322745, Length=435, Percent_Identity=39.7701149425287, Blast_Score=297, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6323731, Length=428, Percent_Identity=30.8411214953271, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6323730, Length=207, Percent_Identity=34.2995169082126, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323958, Length=246, Percent_Identity=29.2682926829268, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21357745, Length=686, Percent_Identity=38.0466472303207, Blast_Score=419, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 66331; Mature: 66331

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIIGIIGNDEVAPRLVDALKRLEYRGYDSAGIATLQNGRLDRRRAEGKLVNLEKRLAG
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHCCCEEEHHHHHCC
EPLPGVIGIGHTRWATHGRPVEHNAHPHITTRLAVVHNGIIENFAELRAMLEAEGRKFET
CCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ETDTEAVAHLVTRELEKGKSPVEAVRDCLPHLKGAFALAFLFEGDEELLIGARQGPPLAV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCEEE
GYGEGEMFLGSDAIALAPFTDTISYLEDGDWAVLTRNGVSIYDENNKPVERPVQKSQNTN
ECCCCCEEECCCCEEECCHHHHHHHHCCCCEEEEEECCEEEEECCCCCHHHHHHHCCCCC
MLVSKGNHRHFMQKEMFEQPEVISHTLANYLDFTTGKVRKEAIGIDFSKVDRLTITACGT
EEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCEEEEEECCH
AYYAATVAKYWFEQIARLPVDSDIASEFRYREMPLSKDSLAMFVSQSGETADTLASLRYC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
KAQGLKIASVLNVTGSTIARESDAVFPTLAGPEIGVASTKAFTCQLSAMASLAIAAARAR
HHCCCEEEHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHC
GAIDEVREQELVHQLSEAPRFINQVLKLEDQIAVVCHDLSKVNHVLYLGRGTSFPLAMEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEECC
ALKLKEISYIHAEGYAAGELKHGPIALIDETMPVIVIAPSDRLYEKTVSNMQEVAARGGR
CEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCE
IILITDKKGAESASIDTMATIVLPEVPEFISPLVYALPIQMLAYHTAVLMGTDVDQPRNL
EEEEECCCCCCCCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
AKSVTVE
HHHCCCC
>Mature Secondary Structure
MCGIIGIIGNDEVAPRLVDALKRLEYRGYDSAGIATLQNGRLDRRRAEGKLVNLEKRLAG
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHCCCEEEHHHHHCC
EPLPGVIGIGHTRWATHGRPVEHNAHPHITTRLAVVHNGIIENFAELRAMLEAEGRKFET
CCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ETDTEAVAHLVTRELEKGKSPVEAVRDCLPHLKGAFALAFLFEGDEELLIGARQGPPLAV
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEEEEEECCCEEEEECCCCCCEEE
GYGEGEMFLGSDAIALAPFTDTISYLEDGDWAVLTRNGVSIYDENNKPVERPVQKSQNTN
ECCCCCEEECCCCEEECCHHHHHHHHCCCCEEEEEECCEEEEECCCCCHHHHHHHCCCCC
MLVSKGNHRHFMQKEMFEQPEVISHTLANYLDFTTGKVRKEAIGIDFSKVDRLTITACGT
EEEECCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCEEEEEECCH
AYYAATVAKYWFEQIARLPVDSDIASEFRYREMPLSKDSLAMFVSQSGETADTLASLRYC
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHH
KAQGLKIASVLNVTGSTIARESDAVFPTLAGPEIGVASTKAFTCQLSAMASLAIAAARAR
HHCCCEEEHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHC
GAIDEVREQELVHQLSEAPRFINQVLKLEDQIAVVCHDLSKVNHVLYLGRGTSFPLAMEG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCEEECC
ALKLKEISYIHAEGYAAGELKHGPIALIDETMPVIVIAPSDRLYEKTVSNMQEVAARGGR
CEEEHHEEEEEECCCCCCCCCCCCEEEEECCCCEEEECCCCHHHHHHHHHHHHHHHCCCE
IILITDKKGAESASIDTMATIVLPEVPEFISPLVYALPIQMLAYHTAVLMGTDVDQPRNL
EEEEECCCCCCCCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
AKSVTVE
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA