Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 225686243

GI number: 225686243

Start: 403920

End: 404981

Strand: Direct

Name: galE [H]

Synonym: BMEA_B0414

Alternate gene names: 225686243

Gene position: 403920-404981 (Clockwise)

Preceding gene: 225686242

Following gene: 225686244

Centisome position: 34.07

GC content: 58.29

Gene sequence:

>1062_bases
ATGAAAGTACTGGTCACGGGAAGTCAGGGTTATATCGGCTCGGTCATGGTGCCGATGCTCATCGATGCCGGGCATGAGGT
GTCGGGCTATGATATCGGCCTTTACGAGCATTGCCTGTTCAAGGAAGGCGGGACGGTCATGAATGTGCCCACCATCCGCA
AGGATGTGCGCGATGTCTCGCCGCGCGATCTGGAAGGTTTCGATGCGGTCATCCATCTTGCCGCGCTTTCCAACGATCCG
CTGGGCAACCTCAACGAAGACCTGACCTATGCCATCAACCACCACGCCAGCGTCGCCATGGCAAAGGCCGCAAAACTTGC
TGGGGTAGGGCGCTTTCTCTTTGCCTCATCATGCAGCAATTACGGTATCAGCGATGCCGAACTGATCGACGAAACCGGCG
AATTGAAGCCTGTCACAGCCTATGGCCGCTCCAAGGTGCGGGCGGAACAGGAAATCCGTAAGCTTGCGGATGCGAGCTTC
TGCCCGGTCTATCTGCGGCCCGCAACCGCCTATGGTGTTTCACCCTTCCTGCGCTTCGATATCGTGCTGAACAATCTCGT
TGCCTGGGCGGTGACGAAGGGGCTGATCTATCTGAAATCCGACGGCACACCCTGGCGGCCCATCGTGCATATCCACGATA
TTTCACGCGCTTTCATGGCGGCGATGGAAGCGCCGCGCGAAAAGGTCTGGAATGAAGCGTTCAATGTCGGCTCTACCGCG
CATAACTACCGTATTCGCGATATTGCCGGGGGCGTGGCCGATAATGTGCCGGATTGCCGGATCGAATATGCGCAGGATGC
GGGGCCGGATACGCGGTCCTATCGCGTCAGTTTTGAAAAGCTGGCGCATGTGCTGCCGGAAGCAAAACCGCAATGGGATG
CGGTGGCGGGCACGCGTGAATTGCTTGCTGCCTACAGCCGATCAACCCTGACAGTCGAGGAATTTGAAGGGCCGCGCTTT
CAGCGCATTGCCCATATTCGCAAGCTGATAGCGCAAGGCGTTCTGGATGCCGACCTGCGCCGCATGGACGCCCATTCTCA
CCCCCTGCGGGCGATGGCATGA

Upstream 100 bases:

>100_bases
CCCGATACCCGGTTGTTCTAGGCGGACATGCCATCGGTCAGGTCGTCACGCCTCGACCCCGCGATTAACATGGATTTATC
GCGACGGTGAGGGGATGAAC

Downstream 100 bases:

>100_bases
TGGATAGCGGGGCGCCGGGCCGGGCAGGTGGTGCGGCAATGGCTGCACCGCAACCGGACGGGGCGGCGATCCACCGGCTC
GCCGCCCGGCTCTATCCGAT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKVLVTGSQGYIGSVMVPMLIDAGHEVSGYDIGLYEHCLFKEGGTVMNVPTIRKDVRDVSPRDLEGFDAVIHLAALSNDP
LGNLNEDLTYAINHHASVAMAKAAKLAGVGRFLFASSCSNYGISDAELIDETGELKPVTAYGRSKVRAEQEIRKLADASF
CPVYLRPATAYGVSPFLRFDIVLNNLVAWAVTKGLIYLKSDGTPWRPIVHIHDISRAFMAAMEAPREKVWNEAFNVGSTA
HNYRIRDIAGGVADNVPDCRIEYAQDAGPDTRSYRVSFEKLAHVLPEAKPQWDAVAGTRELLAAYSRSTLTVEEFEGPRF
QRIAHIRKLIAQGVLDADLRRMDAHSHPLRAMA

Sequences:

>Translated_353_residues
MKVLVTGSQGYIGSVMVPMLIDAGHEVSGYDIGLYEHCLFKEGGTVMNVPTIRKDVRDVSPRDLEGFDAVIHLAALSNDP
LGNLNEDLTYAINHHASVAMAKAAKLAGVGRFLFASSCSNYGISDAELIDETGELKPVTAYGRSKVRAEQEIRKLADASF
CPVYLRPATAYGVSPFLRFDIVLNNLVAWAVTKGLIYLKSDGTPWRPIVHIHDISRAFMAAMEAPREKVWNEAFNVGSTA
HNYRIRDIAGGVADNVPDCRIEYAQDAGPDTRSYRVSFEKLAHVLPEAKPQWDAVAGTRELLAAYSRSTLTVEEFEGPRF
QRIAHIRKLIAQGVLDADLRRMDAHSHPLRAMA
>Mature_353_residues
MKVLVTGSQGYIGSVMVPMLIDAGHEVSGYDIGLYEHCLFKEGGTVMNVPTIRKDVRDVSPRDLEGFDAVIHLAALSNDP
LGNLNEDLTYAINHHASVAMAKAAKLAGVGRFLFASSCSNYGISDAELIDETGELKPVTAYGRSKVRAEQEIRKLADASF
CPVYLRPATAYGVSPFLRFDIVLNNLVAWAVTKGLIYLKSDGTPWRPIVHIHDISRAFMAAMEAPREKVWNEAFNVGSTA
HNYRIRDIAGGVADNVPDCRIEYAQDAGPDTRSYRVSFEKLAHVLPEAKPQWDAVAGTRELLAAYSRSTLTVEEFEGPRF
QRIAHIRKLIAQGVLDADLRRMDAHSHPLRAMA

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1786974, Length=280, Percent_Identity=27.5, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38867; Mature: 38867

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGSQGYIGSVMVPMLIDAGHEVSGYDIGLYEHCLFKEGGTVMNVPTIRKDVRDVS
CEEEEECCCCCHHHHHHHHHHCCCCCCCCEECCHHHHHHHHCCCCEEECCHHHHHHHCCC
PRDLEGFDAVIHLAALSNDPLGNLNEDLTYAINHHASVAMAKAAKLAGVGRFLFASSCSN
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
YGISDAELIDETGELKPVTAYGRSKVRAEQEIRKLADASFCPVYLRPATAYGVSPFLRFD
CCCCHHHHHHCCCCCCEEEHHCCHHHHHHHHHHHHHCCCCCCEEEECCHHCCCCHHHHHH
IVLNNLVAWAVTKGLIYLKSDGTPWRPIVHIHDISRAFMAAMEAPREKVWNEAFNVGSTA
HHHHHHHHHHHHHCEEEEECCCCCCCCEEEEHHHHHHHHHHHHCHHHHHHHHHHCCCCCC
HNYRIRDIAGGVADNVPDCRIEYAQDAGPDTRSYRVSFEKLAHVLPEAKPQWDAVAGTRE
CCEEEHHHHCCCCCCCCCCEEEECCCCCCCCHHHEECHHHHHHHCCCCCCCHHHHHHHHH
LLAAYSRSTLTVEEFEGPRFQRIAHIRKLIAQGVLDADLRRMDAHSHPLRAMA
HHHHHCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKVLVTGSQGYIGSVMVPMLIDAGHEVSGYDIGLYEHCLFKEGGTVMNVPTIRKDVRDVS
CEEEEECCCCCHHHHHHHHHHCCCCCCCCEECCHHHHHHHHCCCCEEECCHHHHHHHCCC
PRDLEGFDAVIHLAALSNDPLGNLNEDLTYAINHHASVAMAKAAKLAGVGRFLFASSCSN
CCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
YGISDAELIDETGELKPVTAYGRSKVRAEQEIRKLADASFCPVYLRPATAYGVSPFLRFD
CCCCHHHHHHCCCCCCEEEHHCCHHHHHHHHHHHHHCCCCCCEEEECCHHCCCCHHHHHH
IVLNNLVAWAVTKGLIYLKSDGTPWRPIVHIHDISRAFMAAMEAPREKVWNEAFNVGSTA
HHHHHHHHHHHHHCEEEEECCCCCCCCEEEEHHHHHHHHHHHHCHHHHHHHHHHCCCCCC
HNYRIRDIAGGVADNVPDCRIEYAQDAGPDTRSYRVSFEKLAHVLPEAKPQWDAVAGTRE
CCEEEHHHHCCCCCCCCCCEEEECCCCCCCCHHHEECHHHHHHHCCCCCCCHHHHHHHHH
LLAAYSRSTLTVEEFEGPRFQRIAHIRKLIAQGVLDADLRRMDAHSHPLRAMA
HHHHHCCCCEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2116013; 14602910 [H]