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The map label for this gene is qorA [H]

Identifier: 225686206

GI number: 225686206

Start: 352781

End: 353788

Strand: Direct

Name: qorA [H]

Synonym: BMEA_B0372

Alternate gene names: 225686206

Gene position: 352781-353788 (Clockwise)

Preceding gene: 225686205

Following gene: 225686207

Centisome position: 29.76

GC content: 59.52

Gene sequence:

>1008_bases
ATGCCTAAAGCGGTTTTGTCTGTCATTGCCACCCGCCCTGGTGGTCCTGAAGTTCTTGAGCTCGTTCCGCGTGAACTACC
AGCGTTGAAGAGGGGTGAAATGCGCGTGCGTATCCACGCCGCTGGTGTCAACCGGCCCGATGCAATGCAGCGTGCCGGTC
AATATCCGCCGCCGCCAGGCGTAACGGATGTCTTGGGGCTGGAGCTTTCCGGTGTTGTTCTGGAAATCGCGGAAGATGTA
ACCCGGTTTGGTCCGGGCGACCGCATCATGGCGCTTGTCGCGGGCGGTGCCTATTCTGAAGAAGCCATTGTGCAGGCTGA
TGTCTGCATTCCTGTGCCAGCAGGCCTCTCGATGGTCGAGGCCGCAGGTATCCCTGAAACCTATTTCACTGTCTGGAGCA
ATCTCTTTCAGCGCGCAGGCCTGCAACCCGGCGAAACCGTTCTTCTGCATGGGGGCACCTCAGGTATTGGCGTGACGGCG
ACGCTTCTGGCCAAGGCAATCGGTGCGCGCATGATCACCACATGCGGGTCCGATGATAAGTGCCGTGCCTCGGAGGCACT
TGGCGCTATCGCTTCGATCAATTATCGCACCACGGATTTTGTCGAGGCAGGTCGGGCGCTGACCGAGGGACGGGGGCCAG
AAGTCGTCATCGATATGGTGGGCGGCAGCTACATGCAGCGTAATCTGCAACTGGTTGCCGAGGATGGACGCATCGCACAG
ATCGCGTTCCAGCAGGGATCGGAGGCGCAGATGGATATGGGGCCATTGCTCTTCAAGCGCCTGACTCTGACGGGTTCAAC
GCTGCGGGCGCGGCCATTGGTGATGAAGGCCGCATTGGCCAGATCGGTCGAAGCAGAGGTCTTACCGCTTGTTTTGAACA
AGGGTGCGCGGCCCGTCATCGATTCCGTATTCGACCTCGCCGACGTGCAGGCCGCCCATGCGCATCTCGAAGCTTCGGCT
CATACAGGCAAGATCATCCTTAAAACCGCGGCTTGTGATGCAGCGTGA

Upstream 100 bases:

>100_bases
GTATGCGTTCGATTGCGAGGTGTCTTCTTCGGAAAAGCGGTCGTCGACGTGACGTACCCCGACCATGTTGTCATGTTCCT
GTTTTCCGAAAGTGTTCAGA

Downstream 100 bases:

>100_bases
CGCGAGGTTGGGCGGGCTGCGCGCAATACGGCTCAATGCGGAAAGCGGCCCGAAACACAAATAATTCTTTGAGGGAGAAA
AGAATGAGACTGTCCAGGCT

Product: quinone oxidoreductase, PIG3 family protein

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPKAVLSVIATRPGGPEVLELVPRELPALKRGEMRVRIHAAGVNRPDAMQRAGQYPPPPGVTDVLGLELSGVVLEIAEDV
TRFGPGDRIMALVAGGAYSEEAIVQADVCIPVPAGLSMVEAAGIPETYFTVWSNLFQRAGLQPGETVLLHGGTSGIGVTA
TLLAKAIGARMITTCGSDDKCRASEALGAIASINYRTTDFVEAGRALTEGRGPEVVIDMVGGSYMQRNLQLVAEDGRIAQ
IAFQQGSEAQMDMGPLLFKRLTLTGSTLRARPLVMKAALARSVEAEVLPLVLNKGARPVIDSVFDLADVQAAHAHLEASA
HTGKIILKTAACDAA

Sequences:

>Translated_335_residues
MPKAVLSVIATRPGGPEVLELVPRELPALKRGEMRVRIHAAGVNRPDAMQRAGQYPPPPGVTDVLGLELSGVVLEIAEDV
TRFGPGDRIMALVAGGAYSEEAIVQADVCIPVPAGLSMVEAAGIPETYFTVWSNLFQRAGLQPGETVLLHGGTSGIGVTA
TLLAKAIGARMITTCGSDDKCRASEALGAIASINYRTTDFVEAGRALTEGRGPEVVIDMVGGSYMQRNLQLVAEDGRIAQ
IAFQQGSEAQMDMGPLLFKRLTLTGSTLRARPLVMKAALARSVEAEVLPLVLNKGARPVIDSVFDLADVQAAHAHLEASA
HTGKIILKTAACDAA
>Mature_334_residues
PKAVLSVIATRPGGPEVLELVPRELPALKRGEMRVRIHAAGVNRPDAMQRAGQYPPPPGVTDVLGLELSGVVLEIAEDVT
RFGPGDRIMALVAGGAYSEEAIVQADVCIPVPAGLSMVEAAGIPETYFTVWSNLFQRAGLQPGETVLLHGGTSGIGVTAT
LLAKAIGARMITTCGSDDKCRASEALGAIASINYRTTDFVEAGRALTEGRGPEVVIDMVGGSYMQRNLQLVAEDGRIAQI
AFQQGSEAQMDMGPLLFKRLTLTGSTLRARPLVMKAALARSVEAEVLPLVLNKGARPVIDSVFDLADVQAAHAHLEASAH
TGKIILKTAACDAA

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=37.0481927710843, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=37.0481927710843, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI194239674, Length=322, Percent_Identity=27.639751552795, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI13236495, Length=322, Percent_Identity=27.639751552795, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI24308257, Length=331, Percent_Identity=25.0755287009063, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI18379349, Length=309, Percent_Identity=26.8608414239482, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI41872631, Length=305, Percent_Identity=28.1967213114754, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI194239676, Length=192, Percent_Identity=29.6875, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI47519420, Length=219, Percent_Identity=29.6803652968037, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI28557745, Length=272, Percent_Identity=29.0441176470588, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI67078404, Length=273, Percent_Identity=26.3736263736264, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI197927207, Length=199, Percent_Identity=26.1306532663317, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1790485, Length=323, Percent_Identity=31.5789473684211, Blast_Score=125, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17507255, Length=326, Percent_Identity=29.1411042944785, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI212642053, Length=307, Percent_Identity=26.3843648208469, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=337, Percent_Identity=24.6290801186944, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24581345, Length=306, Percent_Identity=26.797385620915, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920632, Length=306, Percent_Identity=26.797385620915, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI221330659, Length=274, Percent_Identity=27.3722627737226, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI45550423, Length=271, Percent_Identity=26.9372693726937, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35135; Mature: 35004

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKAVLSVIATRPGGPEVLELVPRELPALKRGEMRVRIHAAGVNRPDAMQRAGQYPPPPG
CCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCC
VTDVLGLELSGVVLEIAEDVTRFGPGDRIMALVAGGAYSEEAIVQADVCIPVPAGLSMVE
CHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECEEEECCCCCHHHH
AAGIPETYFTVWSNLFQRAGLQPGETVLLHGGTSGIGVTATLLAKAIGARMITTCGSDDK
HCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEECCCCCC
CRASEALGAIASINYRTTDFVEAGRALTEGRGPEVVIDMVGGSYMQRNLQLVAEDGRIAQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCEEEEECCCCEEE
IAFQQGSEAQMDMGPLLFKRLTLTGSTLRARPLVMKAALARSVEAEVLPLVLNKGARPVI
EEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
DSVFDLADVQAAHAHLEASAHTGKIILKTAACDAA
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
PKAVLSVIATRPGGPEVLELVPRELPALKRGEMRVRIHAAGVNRPDAMQRAGQYPPPPG
CHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCC
VTDVLGLELSGVVLEIAEDVTRFGPGDRIMALVAGGAYSEEAIVQADVCIPVPAGLSMVE
CHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCEEEECEEEECCCCCHHHH
AAGIPETYFTVWSNLFQRAGLQPGETVLLHGGTSGIGVTATLLAKAIGARMITTCGSDDK
HCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHEEEECCCCCC
CRASEALGAIASINYRTTDFVEAGRALTEGRGPEVVIDMVGGSYMQRNLQLVAEDGRIAQ
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCEEEEECCCCEEE
IAFQQGSEAQMDMGPLLFKRLTLTGSTLRARPLVMKAALARSVEAEVLPLVLNKGARPVI
EEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
DSVFDLADVQAAHAHLEASAHTGKIILKTAACDAA
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]