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The map label for this gene is minC [H]

Identifier: 225686161

GI number: 225686161

Start: 302248

End: 303009

Strand: Direct

Name: minC [H]

Synonym: BMEA_B0320

Alternate gene names: 225686161

Gene position: 302248-303009 (Clockwise)

Preceding gene: 225686160

Following gene: 225686162

Centisome position: 25.5

GC content: 61.81

Gene sequence:

>762_bases
TTGCCGTTAACCAAGATGAATCAAGTGCTAACAGAAACTCGCCCGATCCGCCTTAAAGGGCGGTCCTTTCTTGCAATGGT
GCTCTCGCCGGAACTTCCGCTCGACGGCTGGCTGGAGCGCCTGGACGATCTCGCCCGGCGTTCCTCCGGTTTTTTCCTCG
GGCGCCCGGTTGTGCTCGATATGGAAAACCTTGCCATCGAACGTGCGCAGCTCGTCTATCTGTTGCAGGCGTTGAACGAT
CGCGGCGTCTGGATCATGGGCGTGGAAGGCGCGCGGCCTTCGCTTCTCGGGCCGGGAATGCCGCCTGCCATGCGCGGCGG
CCAGCCCGCAGCCGATTTTGAAGCACCCGCTGGTGAGCCGCAGGCAAATCCTGGCGCGCCGGAACCGCAGATTTCGCAAG
CCGTGCGTGCGCCAGGCCATGCCGTGCACGCCATGCCTTCGATGGTTATCACCGAGCCGGTCCGTTCCGGCCAGTCGGTC
TATTTCCCGGAAGGGGATGTCACAATTGTCGGTTCGGTTGCTTCGGGTGCGGAAGTGGTCGCAGGCGGTTCGATCCATAT
TTACGGCACGCTGCGCGGGCGGGCGCTGGCGGGGACGGCGGGGAATACGAGTGCGCGAATTTTCTGTCGCAAGCTCGAAG
CGGAATTGGTTGCCATCGATGGTCTCTACAAGACCGCCGAGGATCTGGAGCCGAGGTTCCGCGGACAGGCCGTCCAACTC
TGGCTCGACGGCGATTACATGATGATTGATACATTGAGCTGA

Upstream 100 bases:

>100_bases
TGGAGCATACCCATCGCAGGGGTGCTCTCCGGCCGGTTTCATCGGTTGATATTGGTGAAATTAACCTTCCGTTAACCATT
CCGCCCTTAGACCTCTTAAC

Downstream 100 bases:

>100_bases
AGTCGCCGGGGGCGTCAGGAGATGAATATGGGAAAAGTTATCGTAGTGACCTCTGGTAAAGGAGGTGTCGGCAAGACAAC
CTCCACAGCCGCGCTCGGCG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MPLTKMNQVLTETRPIRLKGRSFLAMVLSPELPLDGWLERLDDLARRSSGFFLGRPVVLDMENLAIERAQLVYLLQALND
RGVWIMGVEGARPSLLGPGMPPAMRGGQPAADFEAPAGEPQANPGAPEPQISQAVRAPGHAVHAMPSMVITEPVRSGQSV
YFPEGDVTIVGSVASGAEVVAGGSIHIYGTLRGRALAGTAGNTSARIFCRKLEAELVAIDGLYKTAEDLEPRFRGQAVQL
WLDGDYMMIDTLS

Sequences:

>Translated_253_residues
MPLTKMNQVLTETRPIRLKGRSFLAMVLSPELPLDGWLERLDDLARRSSGFFLGRPVVLDMENLAIERAQLVYLLQALND
RGVWIMGVEGARPSLLGPGMPPAMRGGQPAADFEAPAGEPQANPGAPEPQISQAVRAPGHAVHAMPSMVITEPVRSGQSV
YFPEGDVTIVGSVASGAEVVAGGSIHIYGTLRGRALAGTAGNTSARIFCRKLEAELVAIDGLYKTAEDLEPRFRGQAVQL
WLDGDYMMIDTLS
>Mature_252_residues
PLTKMNQVLTETRPIRLKGRSFLAMVLSPELPLDGWLERLDDLARRSSGFFLGRPVVLDMENLAIERAQLVYLLQALNDR
GVWIMGVEGARPSLLGPGMPPAMRGGQPAADFEAPAGEPQANPGAPEPQISQAVRAPGHAVHAMPSMVITEPVRSGQSVY
FPEGDVTIVGSVASGAEVVAGGSIHIYGTLRGRALAGTAGNTSARIFCRKLEAELVAIDGLYKTAEDLEPRFRGQAVQLW
LDGDYMMIDTLS

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=245, Percent_Identity=31.4285714285714, Blast_Score=113, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C [H]

EC number: NA

Molecular weight: Translated: 27160; Mature: 27028

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTKMNQVLTETRPIRLKGRSFLAMVLSPELPLDGWLERLDDLARRSSGFFLGRPVVLD
CCCHHHHHHHHCCCCEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCEEEE
MENLAIERAQLVYLLQALNDRGVWIMGVEGARPSLLGPGMPPAMRGGQPAADFEAPAGEP
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
QANPGAPEPQISQAVRAPGHAVHAMPSMVITEPVRSGQSVYFPEGDVTIVGSVASGAEVV
CCCCCCCCHHHHHHHHCCCCHHHHCCHHHEEHHHHCCCEEEECCCCEEEEEECCCCCEEE
AGGSIHIYGTLRGRALAGTAGNTSARIFCRKLEAELVAIDGLYKTAEDLEPRFRGQAVQL
ECCEEEEEEEECCEEEECCCCCCCCEEEEEECCCEEEEECCHHHHHHHCCHHHCCCEEEE
WLDGDYMMIDTLS
EECCCEEEEEECC
>Mature Secondary Structure 
PLTKMNQVLTETRPIRLKGRSFLAMVLSPELPLDGWLERLDDLARRSSGFFLGRPVVLD
CCHHHHHHHHCCCCEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEECCCEEEE
MENLAIERAQLVYLLQALNDRGVWIMGVEGARPSLLGPGMPPAMRGGQPAADFEAPAGEP
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCC
QANPGAPEPQISQAVRAPGHAVHAMPSMVITEPVRSGQSVYFPEGDVTIVGSVASGAEVV
CCCCCCCCHHHHHHHHCCCCHHHHCCHHHEEHHHHCCCEEEECCCCEEEEEECCCCCEEE
AGGSIHIYGTLRGRALAGTAGNTSARIFCRKLEAELVAIDGLYKTAEDLEPRFRGQAVQL
ECCEEEEEEEECCEEEECCCCCCCCEEEEEECCCEEEEECCHHHHHHHCCHHHCCCEEEE
WLDGDYMMIDTLS
EECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA