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The map label for this gene is engA [H]

Identifier: 225630952

GI number: 225630952

Start: 1362969

End: 1364294

Strand: Direct

Name: engA [H]

Synonym: WRi_012740

Alternate gene names: 225630952

Gene position: 1362969-1364294 (Clockwise)

Preceding gene: 225630950

Following gene: 225630953

Centisome position: 94.27

GC content: 37.33

Gene sequence:

>1326_bases
ATGCTAAAAATCGCCATAGTAGGCCTACCAAATGCTGGAAAATCGACCCTATTCAACAGATTAGTAGGAAGAAAAGCAGC
AGTAGTGAGTAACATTCCAGGAGTGACAAGGGATAGGCGAGAGGGAATGGGGAGAATTAGCGATTTGGAGTTTAAAGTTA
TAGATACAGGAGGATGGAACGACCAAACTAGTTTTTCACTGCAAGTTATTGAGCAAATAGAGTTTTCTTTATCCAGTTCA
AACATAATTTTCTTTCTTGTTGACGCAAAAGTGCAAAATGAGCGAAATAAAGAGTTTGCAAAGTGGCTGAAGAGAAAAAT
AAATAAACCTGTGATACTGATAGCAAATAAATGCGAGAGTCATAAATCCGAAAATGTTGATTATTTGCAGTTTTTTGATT
TTCTTGGCCCGGTGTATATCTCTGCCGAGCATAATCTTGGCATGGTTGATCTTTATGATGCATTAGCTGGTGTTATTGAA
AATTTTAACGAGAACACTGAGTTACCTAACAATGAACTGAGTAGGCTGAGGATCGCGATCATCGGACGTCCGAATGTTGG
AAAATCAACTTTTTTAAATGGTTTACTTGCAGAAAACAGACTAATAACAAGTTCAGAGCCAGGTACCACACGTGATTCTG
TGGATATTACATATGATCATGATGGAGAGTTAATTACTCTAATTGACACTGCCGGAATCCGCAGAAAGGCGAATGTTGTA
GATGGCTTAGAATCAAGATTTGTTGAGAAAAGCATGGAATCAATCAAGCGCTCTCATGTGGTAGTTTTAATGCTAGACTC
CCTAGTTGGTATTGAGCAGCAGGATTTATCAATTGGTGAAGCTGCAATTAAGGGAGGGAAAGGGATTATTGTTGTTTTAA
ATAAGTGGGATTTAATAGGTAAGGATGACAGAAGCAGGTTAATAAAATTTGTCAAACAACAGGAAGTAACCAGGTTATTC
TTGGAAGTGCCAACTATAACAATTTCTGCGTTAAAAGGCATGCGCTGCGGTGATGTGATAGATAAGTGTCTTGAAGTGAG
TGAATCCTTGAACAAGAAGATCAGCACTGCAAAACTGAATAAGTGGCTCATAGATGCTGTAGGAAAACATTCTCACCCTC
TTGTAAAAGGCAAAGCAGTTAAAATGAAGTATATCGCTCAAATTGGTACTAAACCTCCAGCTTTTTCTTTGATATGTAAC
ATACCTGAAAGTGTTGATGAAAGTTACAAACGCTATTTAATTAACGATCTCAGAAAAAATTTCTTTGCAGACGGTGTGCC
AGTTAGATTGCTTTTGAAAAAAAATAAAAATCCCTATGTAAAATGA

Upstream 100 bases:

>100_bases
AAAATTCTAACTGTAGTATGCTTATATAATCTACGAAGTCAATAGTTAAATTGAAAAGTTTCGGTTATAATTTACTTCAT
ATAGAACATGCCCTTGAATT

Downstream 100 bases:

>100_bases
ATACTCTGCTTTATACTTTCAGGGATAATTTACTTAAAGTTATGTGTAATAATTCCAGAATTCCTGCAATCTTTCTGCTG
TCGAGTGCCGCTGCTCTAAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MLKIAIVGLPNAGKSTLFNRLVGRKAAVVSNIPGVTRDRREGMGRISDLEFKVIDTGGWNDQTSFSLQVIEQIEFSLSSS
NIIFFLVDAKVQNERNKEFAKWLKRKINKPVILIANKCESHKSENVDYLQFFDFLGPVYISAEHNLGMVDLYDALAGVIE
NFNENTELPNNELSRLRIAIIGRPNVGKSTFLNGLLAENRLITSSEPGTTRDSVDITYDHDGELITLIDTAGIRRKANVV
DGLESRFVEKSMESIKRSHVVVLMLDSLVGIEQQDLSIGEAAIKGGKGIIVVLNKWDLIGKDDRSRLIKFVKQQEVTRLF
LEVPTITISALKGMRCGDVIDKCLEVSESLNKKISTAKLNKWLIDAVGKHSHPLVKGKAVKMKYIAQIGTKPPAFSLICN
IPESVDESYKRYLINDLRKNFFADGVPVRLLLKKNKNPYVK

Sequences:

>Translated_441_residues
MLKIAIVGLPNAGKSTLFNRLVGRKAAVVSNIPGVTRDRREGMGRISDLEFKVIDTGGWNDQTSFSLQVIEQIEFSLSSS
NIIFFLVDAKVQNERNKEFAKWLKRKINKPVILIANKCESHKSENVDYLQFFDFLGPVYISAEHNLGMVDLYDALAGVIE
NFNENTELPNNELSRLRIAIIGRPNVGKSTFLNGLLAENRLITSSEPGTTRDSVDITYDHDGELITLIDTAGIRRKANVV
DGLESRFVEKSMESIKRSHVVVLMLDSLVGIEQQDLSIGEAAIKGGKGIIVVLNKWDLIGKDDRSRLIKFVKQQEVTRLF
LEVPTITISALKGMRCGDVIDKCLEVSESLNKKISTAKLNKWLIDAVGKHSHPLVKGKAVKMKYIAQIGTKPPAFSLICN
IPESVDESYKRYLINDLRKNFFADGVPVRLLLKKNKNPYVK
>Mature_441_residues
MLKIAIVGLPNAGKSTLFNRLVGRKAAVVSNIPGVTRDRREGMGRISDLEFKVIDTGGWNDQTSFSLQVIEQIEFSLSSS
NIIFFLVDAKVQNERNKEFAKWLKRKINKPVILIANKCESHKSENVDYLQFFDFLGPVYISAEHNLGMVDLYDALAGVIE
NFNENTELPNNELSRLRIAIIGRPNVGKSTFLNGLLAENRLITSSEPGTTRDSVDITYDHDGELITLIDTAGIRRKANVV
DGLESRFVEKSMESIKRSHVVVLMLDSLVGIEQQDLSIGEAAIKGGKGIIVVLNKWDLIGKDDRSRLIKFVKQQEVTRLF
LEVPTITISALKGMRCGDVIDKCLEVSESLNKKISTAKLNKWLIDAVGKHSHPLVKGKAVKMKYIAQIGTKPPAFSLICN
IPESVDESYKRYLINDLRKNFFADGVPVRLLLKKNKNPYVK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=466, Percent_Identity=33.6909871244635, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI2367268, Length=124, Percent_Identity=32.258064516129, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=91, Percent_Identity=38.4615384615385, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=192, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49313; Mature: 49313

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIAIVGLPNAGKSTLFNRLVGRKAAVVSNIPGVTRDRREGMGRISDLEFKVIDTGGWN
CEEEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEECCCCC
DQTSFSLQVIEQIEFSLSSSNIIFFLVDAKVQNERNKEFAKWLKRKINKPVILIANKCES
CCCHHHHHHHHHHHHHCCCCCEEEEEEECHHCCCCCHHHHHHHHHHCCCCEEEEECCCCC
HKSENVDYLQFFDFLGPVYISAEHNLGMVDLYDALAGVIENFNENTELPNNELSRLRIAI
CCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
IGRPNVGKSTFLNGLLAENRLITSSEPGTTRDSVDITYDHDGELITLIDTAGIRRKANVV
EECCCCCHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHH
DGLESRFVEKSMESIKRSHVVVLMLDSLVGIEQQDLSIGEAAIKGGKGIIVVLNKWDLIG
HHHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHCCCCCHHHHCCCCEEEEEEECCCCCC
KDDRSRLIKFVKQQEVTRLFLEVPTITISALKGMRCGDVIDKCLEVSESLNKKISTAKLN
CCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KWLIDAVGKHSHPLVKGKAVKMKYIAQIGTKPPAFSLICNIPESVDESYKRYLINDLRKN
HHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
FFADGVPVRLLLKKNKNPYVK
HCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MLKIAIVGLPNAGKSTLFNRLVGRKAAVVSNIPGVTRDRREGMGRISDLEFKVIDTGGWN
CEEEEEEECCCCCHHHHHHHHHCCHHHHHHCCCCCCCHHHHCCCCCCCCEEEEEECCCCC
DQTSFSLQVIEQIEFSLSSSNIIFFLVDAKVQNERNKEFAKWLKRKINKPVILIANKCES
CCCHHHHHHHHHHHHHCCCCCEEEEEEECHHCCCCCHHHHHHHHHHCCCCEEEEECCCCC
HKSENVDYLQFFDFLGPVYISAEHNLGMVDLYDALAGVIENFNENTELPNNELSRLRIAI
CCCCCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEE
IGRPNVGKSTFLNGLLAENRLITSSEPGTTRDSVDITYDHDGELITLIDTAGIRRKANVV
EECCCCCHHHHHHHHHHCCEEEECCCCCCCCCCEEEEECCCCCEEEEEECCCCCHHHHHH
DGLESRFVEKSMESIKRSHVVVLMLDSLVGIEQQDLSIGEAAIKGGKGIIVVLNKWDLIG
HHHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHCCCCCHHHHCCCCEEEEEEECCCCCC
KDDRSRLIKFVKQQEVTRLFLEVPTITISALKGMRCGDVIDKCLEVSESLNKKISTAKLN
CCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KWLIDAVGKHSHPLVKGKAVKMKYIAQIGTKPPAFSLICNIPESVDESYKRYLINDLRKN
HHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
FFADGVPVRLLLKKNKNPYVK
HCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA