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The map label for this gene is mreB [H]

Identifier: 225630916

GI number: 225630916

Start: 1324047

End: 1325123

Strand: Direct

Name: mreB [H]

Synonym: WRi_012320

Alternate gene names: 225630916

Gene position: 1324047-1325123 (Clockwise)

Preceding gene: 225630915

Following gene: 225630917

Centisome position: 91.57

GC content: 37.88

Gene sequence:

>1077_bases
ATGAATTTTGTTCGAAAATTAACCGGAAAGTTTTATAGCCTTTTTACTTTCAAAGGTTTGTTTGCTAGCGATATTGCTAT
AGATCTTGGCACTGCAAACACTTTAGTTTATCAGAAAAATCAGGGAATAGTGCTTGATGAGCCTTCAGTTGTAGCAAGAA
TAAAAGAAAAAGGAAGCTACGTTCCTTATGCTTTTGGTAAAAAAGCTAAAATGATGCTTGGAAAAACGCCTGGAGAAATA
GAGGCGATAAGGCCCTTAAAGGATGGAGTTATTGCTGATTTTAAAAGTGCGGAAGAAATGCTAAAATATTTCATACGCAG
TGCAAACACAAAATTCACTGTTAATAAACCTAATATTATCATATGCGTTCCATCTGGATCCACGCCAGTTGAAAGGCGTG
CTATACAAGATGCAGCAGAAAGTGCTGGTGCAAATGAAGTATTTTTAATTGAAGAACCAATGGCTGCAGCAATCGGAGCT
GGGCTCCCGGTTACTGAACCTGAGGGTTCTATGATCGTTGATATAGGAGGCGGTACAACTGAAGTTGCAATTATTTCTTT
AGGCGGAATTGTTTATTCACGTTCTGCCAGAGTAGGTGGCGATATTATGGATGAAGCAATAAAATCATATATTCGTGAAA
ATCATAAGTTATTAATCGGTGAAACAACCGCTGAGAAAATTAAGAAAAGCATAGGTTCAGCTAGTCTGCCAGGTGAAAAT
AACAAAGAGGGAATGATAATTAAAGGCAGGGATTTAGTGAGTGGCATGCCAAAAGAAATGCTTTTATCAGAATACCAAGT
TGCAGAGAGTTTAATAGAGCCTGTACATCAGATAATTTCTGCTATTAAGACTGCGCTGGAGAGCACTCCACCTGAACTTT
CTTCTGATATAGTCGATAGAGGAATAGTTTTATCCGGTGGTGGTGGATTATTACGTAATCTAGGTAAAGTTATCAGTGAA
ACAACAAAATTACCGGTTCGTGTTGCAGATGACCCACTTTGTTGTGTTGCCTTAGGTAGTGGAAAAGTGCTTGAAAACAT
GGATTATTTTGGCCATGTTTTATTCAAGCAAGATTAA

Upstream 100 bases:

>100_bases
TAAAAAAAGTAACAGGTAAGGGTTTAGACGTTGAGTGTGTTACTTACTACTTATCTGAAAAGTATAATTTGTCTTAATAA
ATGGTTTTCTTGAGTTATGT

Downstream 100 bases:

>100_bases
ATTATTTTTGAAGGTAGTTTATTGAATTGTTTTGATGGAATTATGTAATATAAATGAGATCCCAGTGTCATGCACCAAGT
AATTTGAAGGCAACTTCTAG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNFVRKLTGKFYSLFTFKGLFASDIAIDLGTANTLVYQKNQGIVLDEPSVVARIKEKGSYVPYAFGKKAKMMLGKTPGEI
EAIRPLKDGVIADFKSAEEMLKYFIRSANTKFTVNKPNIIICVPSGSTPVERRAIQDAAESAGANEVFLIEEPMAAAIGA
GLPVTEPEGSMIVDIGGGTTEVAIISLGGIVYSRSARVGGDIMDEAIKSYIRENHKLLIGETTAEKIKKSIGSASLPGEN
NKEGMIIKGRDLVSGMPKEMLLSEYQVAESLIEPVHQIISAIKTALESTPPELSSDIVDRGIVLSGGGGLLRNLGKVISE
TTKLPVRVADDPLCCVALGSGKVLENMDYFGHVLFKQD

Sequences:

>Translated_358_residues
MNFVRKLTGKFYSLFTFKGLFASDIAIDLGTANTLVYQKNQGIVLDEPSVVARIKEKGSYVPYAFGKKAKMMLGKTPGEI
EAIRPLKDGVIADFKSAEEMLKYFIRSANTKFTVNKPNIIICVPSGSTPVERRAIQDAAESAGANEVFLIEEPMAAAIGA
GLPVTEPEGSMIVDIGGGTTEVAIISLGGIVYSRSARVGGDIMDEAIKSYIRENHKLLIGETTAEKIKKSIGSASLPGEN
NKEGMIIKGRDLVSGMPKEMLLSEYQVAESLIEPVHQIISAIKTALESTPPELSSDIVDRGIVLSGGGGLLRNLGKVISE
TTKLPVRVADDPLCCVALGSGKVLENMDYFGHVLFKQD
>Mature_358_residues
MNFVRKLTGKFYSLFTFKGLFASDIAIDLGTANTLVYQKNQGIVLDEPSVVARIKEKGSYVPYAFGKKAKMMLGKTPGEI
EAIRPLKDGVIADFKSAEEMLKYFIRSANTKFTVNKPNIIICVPSGSTPVERRAIQDAAESAGANEVFLIEEPMAAAIGA
GLPVTEPEGSMIVDIGGGTTEVAIISLGGIVYSRSARVGGDIMDEAIKSYIRENHKLLIGETTAEKIKKSIGSASLPGEN
NKEGMIIKGRDLVSGMPKEMLLSEYQVAESLIEPVHQIISAIKTALESTPPELSSDIVDRGIVLSGGGGLLRNLGKVISE
TTKLPVRVADDPLCCVALGSGKVLENMDYFGHVLFKQD

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=349, Percent_Identity=57.0200573065903, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1788875, Length=230, Percent_Identity=26.5217391304348, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 38386; Mature: 38386

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFVRKLTGKFYSLFTFKGLFASDIAIDLGTANTLVYQKNQGIVLDEPSVVARIKEKGSY
CCHHHHHHHHHHHHHHHHCHHHCCEEEEECCCEEEEEECCCCEEECCCHHHHHHHHCCCC
VPYAFGKKAKMMLGKTPGEIEAIRPLKDGVIADFKSAEEMLKYFIRSANTKFTVNKPNII
CCEECCCCHHHEECCCCCCHHHHCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEE
ICVPSGSTPVERRAIQDAAESAGANEVFLIEEPMAAAIGAGLPVTEPEGSMIVDIGGGTT
EEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCCE
EVAIISLGGIVYSRSARVGGDIMDEAIKSYIRENHKLLIGETTAEKIKKSIGSASLPGEN
EEEEEEECCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCCCCCC
NKEGMIIKGRDLVSGMPKEMLLSEYQVAESLIEPVHQIISAIKTALESTPPELSSDIVDR
CCCCEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
GIVLSGGGGLLRNLGKVISETTKLPVRVADDPLCCVALGSGKVLENMDYFGHVLFKQD
CEEEECCCHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCHHHCCHHHEEEEEECC
>Mature Secondary Structure
MNFVRKLTGKFYSLFTFKGLFASDIAIDLGTANTLVYQKNQGIVLDEPSVVARIKEKGSY
CCHHHHHHHHHHHHHHHHCHHHCCEEEEECCCEEEEEECCCCEEECCCHHHHHHHHCCCC
VPYAFGKKAKMMLGKTPGEIEAIRPLKDGVIADFKSAEEMLKYFIRSANTKFTVNKPNII
CCEECCCCHHHEECCCCCCHHHHCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEECCCEEE
ICVPSGSTPVERRAIQDAAESAGANEVFLIEEPMAAAIGAGLPVTEPEGSMIVDIGGGTT
EEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCCE
EVAIISLGGIVYSRSARVGGDIMDEAIKSYIRENHKLLIGETTAEKIKKSIGSASLPGEN
EEEEEEECCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCCCCCC
NKEGMIIKGRDLVSGMPKEMLLSEYQVAESLIEPVHQIISAIKTALESTPPELSSDIVDR
CCCCEEEECCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
GIVLSGGGGLLRNLGKVISETTKLPVRVADDPLCCVALGSGKVLENMDYFGHVLFKQD
CEEEECCCHHHHHHHHHHHHHHCCCEEECCCCEEEEEECCCCHHHCCHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]