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The map label for this gene is aatA [H]

Identifier: 225630692

GI number: 225630692

Start: 1057463

End: 1058656

Strand: Direct

Name: aatA [H]

Synonym: WRi_009850

Alternate gene names: 225630692

Gene position: 1057463-1058656 (Clockwise)

Preceding gene: 225630691

Following gene: 225630693

Centisome position: 73.14

GC content: 36.18

Gene sequence:

>1194_bases
ATGTCAGACCTTGCAAAAAGAATGTTCCTAATAAAACCATCACCTACGATTGCTGTAACTGATAAGGCAAATAAGTTGAA
AAATGAAGGAAAAAAGATCTGTGTTTTAGCTGCAGGAGAACCGGATTTTGATACTCCAGATCATATAAAAAAAGCAGCTA
TTCAAGCAATAAGTGAAGGTAAGACTAAATATACTGCTGTTGATGGAACGCGTGAGCTGAAAGAAGCAATAATTAATAAG
TTAAGAAAGGATAATAACCTCGAGTACACGCTTAACCAAATCTGTGTTGGTACAGGTGCTAAGCAGGTGTTATTCAATTT
GTTCATGGCAACAATTAACTCTGGAGATGAAGTTATTATTCCAGCTCCTTATTGGGTTTCATATGTTGATATGGTAAGTC
TTTTTGGCGGCTTGCCAGTTGTAGTAGAATGCAAACAAAATTTTAAACTGACAGCGGAATTATTGAAAAGCAGGATAACT
AAAAAAACTAAATGGTTAATTCTTAACTCACCGAACAACCCTGCAGGAGCTGTGTACACATGTGATGAATTGAAAGACAT
AGCACAAATATTGCTTGAATATCCACATATGAATGTCGTTACAGATGATATTTATGAGCATATAATATACGACGAAAAGT
TTTTTACTATCGCTCAGGTTGAGCCGAAGCTTTATGATAGAGTTTTTGTAGTCAATGGAGTATCAAAAGCCTATGCAATG
ACAGGCTGGAGAATAGGGTATATTGCAGGTAGAAGTGATGTGGTAAAAGCTATCTCTACGCTGCAGTCTCAAAGCACTTC
TAATCCAAATTCGATAGCACAAGCAGCAGCAGCAGCAGCATTAAACGGTGATCATAGTTTTTTGAAAGAAAGAACAAGGA
TTTTTAAGAGTCGTAGAGATTTTATGGTGAAAGAGCTAAATTCTGCCCCGGGATTATCAGCGTCTGTTCCACAAGGTGCG
TTTTATTTATTTGTCTCATGTGAAGGATTGCTCAGTAAAAGCACAAAAAGTGGTAAGATAATAAATAATGATTTAGATTT
TACTGAATACTTACTGGGAGATCATTTGGTTGCTGTGGTTCCAGGAATTGCATTTGGTCTAGAAAATTTTATCAGAATTT
CTTATGCAACCTCTCAGGAACAATTAGAAATTGGATGTGATAGTATTACTAAAGCGTGCCAGGAGTTAAAATGA

Upstream 100 bases:

>100_bases
TGCGTTGGTAAACCTGGTAAAAAGCTACTAATACAATACACAAAATTCCTAGCTTTTTTGTTGTACGGGGTTTATCATTT
AAATTTAGCTTCAGTAAAAT

Downstream 100 bases:

>100_bases
AATAGACTATCCATAAGTTGTATATTTTGCCATACTTCGCCAAGGTTATTTTGAATGTTCTAACTTGTGTTTTTCTATGG
AAGGCATTTTTATTGATTGA

Product: Aspartate aminotransferase family enzyme

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSDLAKRMFLIKPSPTIAVTDKANKLKNEGKKICVLAAGEPDFDTPDHIKKAAIQAISEGKTKYTAVDGTRELKEAIINK
LRKDNNLEYTLNQICVGTGAKQVLFNLFMATINSGDEVIIPAPYWVSYVDMVSLFGGLPVVVECKQNFKLTAELLKSRIT
KKTKWLILNSPNNPAGAVYTCDELKDIAQILLEYPHMNVVTDDIYEHIIYDEKFFTIAQVEPKLYDRVFVVNGVSKAYAM
TGWRIGYIAGRSDVVKAISTLQSQSTSNPNSIAQAAAAAALNGDHSFLKERTRIFKSRRDFMVKELNSAPGLSASVPQGA
FYLFVSCEGLLSKSTKSGKIINNDLDFTEYLLGDHLVAVVPGIAFGLENFIRISYATSQEQLEIGCDSITKACQELK

Sequences:

>Translated_397_residues
MSDLAKRMFLIKPSPTIAVTDKANKLKNEGKKICVLAAGEPDFDTPDHIKKAAIQAISEGKTKYTAVDGTRELKEAIINK
LRKDNNLEYTLNQICVGTGAKQVLFNLFMATINSGDEVIIPAPYWVSYVDMVSLFGGLPVVVECKQNFKLTAELLKSRIT
KKTKWLILNSPNNPAGAVYTCDELKDIAQILLEYPHMNVVTDDIYEHIIYDEKFFTIAQVEPKLYDRVFVVNGVSKAYAM
TGWRIGYIAGRSDVVKAISTLQSQSTSNPNSIAQAAAAAALNGDHSFLKERTRIFKSRRDFMVKELNSAPGLSASVPQGA
FYLFVSCEGLLSKSTKSGKIINNDLDFTEYLLGDHLVAVVPGIAFGLENFIRISYATSQEQLEIGCDSITKACQELK
>Mature_396_residues
SDLAKRMFLIKPSPTIAVTDKANKLKNEGKKICVLAAGEPDFDTPDHIKKAAIQAISEGKTKYTAVDGTRELKEAIINKL
RKDNNLEYTLNQICVGTGAKQVLFNLFMATINSGDEVIIPAPYWVSYVDMVSLFGGLPVVVECKQNFKLTAELLKSRITK
KTKWLILNSPNNPAGAVYTCDELKDIAQILLEYPHMNVVTDDIYEHIIYDEKFFTIAQVEPKLYDRVFVVNGVSKAYAMT
GWRIGYIAGRSDVVKAISTLQSQSTSNPNSIAQAAAAAALNGDHSFLKERTRIFKSRRDFMVKELNSAPGLSASVPQGAF
YLFVSCEGLLSKSTKSGKIINNDLDFTEYLLGDHLVAVVPGIAFGLENFIRISYATSQEQLEIGCDSITKACQELK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=404, Percent_Identity=25.4950495049505, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI169881279, Length=404, Percent_Identity=25.4950495049505, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI56713256, Length=394, Percent_Identity=28.1725888324873, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI56713254, Length=394, Percent_Identity=28.1725888324873, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI169881281, Length=318, Percent_Identity=24.2138364779874, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4507369, Length=415, Percent_Identity=24.578313253012, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1786816, Length=353, Percent_Identity=25.4957507082153, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788627, Length=321, Percent_Identity=29.2834890965732, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788722, Length=376, Percent_Identity=27.1276595744681, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=327, Percent_Identity=23.8532110091743, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=327, Percent_Identity=23.8532110091743, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=365, Percent_Identity=25.4794520547945, Blast_Score=114, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=401, Percent_Identity=22.9426433915212, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322401, Length=385, Percent_Identity=24.6753246753247, Blast_Score=117, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=341, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573069, Length=328, Percent_Identity=26.5243902439024, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24646114, Length=328, Percent_Identity=26.5243902439024, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28573067, Length=328, Percent_Identity=26.5243902439024, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28573065, Length=328, Percent_Identity=26.5243902439024, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI18859735, Length=386, Percent_Identity=22.7979274611399, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43831; Mature: 43700

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLAKRMFLIKPSPTIAVTDKANKLKNEGKKICVLAAGEPDFDTPDHIKKAAIQAISEG
CCCHHCCEEEECCCCCEEECCCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCC
KTKYTAVDGTRELKEAIINKLRKDNNLEYTLNQICVGTGAKQVLFNLFMATINSGDEVII
CCEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCHHHHHHHHHHHHHCCCCCEEE
PAPYWVSYVDMVSLFGGLPVVVECKQNFKLTAELLKSRITKKTKWLILNSPNNPAGAVYT
CCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
CDELKDIAQILLEYPHMNVVTDDIYEHIIYDEKFFTIAQVEPKLYDRVFVVNGVSKAYAM
HHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEECCHHHHCEEEEEECCHHHHHH
TGWRIGYIAGRSDVVKAISTLQSQSTSNPNSIAQAAAAAALNGDHSFLKERTRIFKSRRD
CCCEEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FMVKELNSAPGLSASVPQGAFYLFVSCEGLLSKSTKSGKIINNDLDFTEYLLGDHLVAVV
HHHHHHCCCCCCCCCCCCCEEEEEEEECHHHCCCCCCCCEECCCCCHHHHHHHCHHHHHH
PGIAFGLENFIRISYATSQEQLEIGCDSITKACQELK
HHHHHHHHHHEEEEECCCHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDLAKRMFLIKPSPTIAVTDKANKLKNEGKKICVLAAGEPDFDTPDHIKKAAIQAISEG
CCHHCCEEEECCCCCEEECCCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCC
KTKYTAVDGTRELKEAIINKLRKDNNLEYTLNQICVGTGAKQVLFNLFMATINSGDEVII
CCEEEECCCHHHHHHHHHHHHHCCCCCEEEEHHHHHCCCHHHHHHHHHHHHHCCCCCEEE
PAPYWVSYVDMVSLFGGLPVVVECKQNFKLTAELLKSRITKKTKWLILNSPNNPAGAVYT
CCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEE
CDELKDIAQILLEYPHMNVVTDDIYEHIIYDEKFFTIAQVEPKLYDRVFVVNGVSKAYAM
HHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCEEEEEECCHHHHCEEEEEECCHHHHHH
TGWRIGYIAGRSDVVKAISTLQSQSTSNPNSIAQAAAAAALNGDHSFLKERTRIFKSRRD
CCCEEEEEECHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FMVKELNSAPGLSASVPQGAFYLFVSCEGLLSKSTKSGKIINNDLDFTEYLLGDHLVAVV
HHHHHHCCCCCCCCCCCCCEEEEEEEECHHHCCCCCCCCEECCCCCHHHHHHHCHHHHHH
PGIAFGLENFIRISYATSQEQLEIGCDSITKACQELK
HHHHHHHHHHEEEEECCCHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA