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The map label for this gene is infC [H]

Identifier: 225630644

GI number: 225630644

Start: 998079

End: 998597

Strand: Reverse

Name: infC [H]

Synonym: WRi_009270

Alternate gene names: 225630644

Gene position: 998597-998079 (Counterclockwise)

Preceding gene: 225630645

Following gene: 225630642

Centisome position: 69.07

GC content: 36.42

Gene sequence:

>519_bases
TTGCAAGTTAAAAAGAACAATAAAAACAGAATTAATGGATTCATCACAGCTAAGGAGGTACGCTTAGTTGATCACAGTGG
TGAAATGATCGGAATCGTGCTAATAGAACGAGCTTTGGAGCTTGCACAGGGTGTTGGTTTAGACTTGGTGGAAATTGCAC
CTGATTCAACCCCTCCAGTATGTAAAATTCTGGATTATAGCAAGCAAAAGTATGATATAAAAAAGAAAGCAAGTGAAGCA
AAAAAGAAACAAAAAACATTAACTATAAAAGAAATTAAACTGGGTCCTAATATTGGTGATCACGACTACGAAACAAAATT
GCGTCAAGCAAGAGACTTACTTGTCCACGGACATAAAATTAAAGTCACAATGAGATTTAGAGGGAGAGAGCTTATAAACA
CTGAAGTTGGACTGGAAAAATTAGAACGGCTAATTCGAGACACTGAAGATATCGCAAAGGTAGAATTGGCACCTAAAAGA
GAAGGGAATCAATATTTTTTAGCTCTGGTTGCTAAGTAG

Upstream 100 bases:

>100_bases
AGTGAGAAATTTAGGATCGGAAAGACAGGAGTCTTTTTCTTTGGAGAAGGCTATTGAATTGTTGTTAAAAAGTATTAATT
TGAATTAAGGGAGTTAAAGT

Downstream 100 bases:

>100_bases
CAAAACGGCTTAAGAGTATCCGTTCAGGAGAGTGGTTTAAGAAACAATAGATAGGAGATTTTGGAAAGGATTGAGACCCC
TTTGTTTCCAAGTTAAGTAT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MQVKKNNKNRINGFITAKEVRLVDHSGEMIGIVLIERALELAQGVGLDLVEIAPDSTPPVCKILDYSKQKYDIKKKASEA
KKKQKTLTIKEIKLGPNIGDHDYETKLRQARDLLVHGHKIKVTMRFRGRELINTEVGLEKLERLIRDTEDIAKVELAPKR
EGNQYFLALVAK

Sequences:

>Translated_172_residues
MQVKKNNKNRINGFITAKEVRLVDHSGEMIGIVLIERALELAQGVGLDLVEIAPDSTPPVCKILDYSKQKYDIKKKASEA
KKKQKTLTIKEIKLGPNIGDHDYETKLRQARDLLVHGHKIKVTMRFRGRELINTEVGLEKLERLIRDTEDIAKVELAPKR
EGNQYFLALVAK
>Mature_172_residues
MQVKKNNKNRINGFITAKEVRLVDHSGEMIGIVLIERALELAQGVGLDLVEIAPDSTPPVCKILDYSKQKYDIKKKASEA
KKKQKTLTIKEIKLGPNIGDHDYETKLRQARDLLVHGHKIKVTMRFRGRELINTEVGLEKLERLIRDTEDIAKVELAPKR
EGNQYFLALVAK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=45.9302325581395, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19568; Mature: 19568

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKKNNKNRINGFITAKEVRLVDHSGEMIGIVLIERALELAQGVGLDLVEIAPDSTPPV
CCCCCCCCCCEEEEEEEEEEEEEECCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCE
CKILDYSKQKYDIKKKASEAKKKQKTLTIKEIKLGPNIGDHDYETKLRQARDLLVHGHKI
EHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEE
KVTMRFRGRELINTEVGLEKLERLIRDTEDIAKVELAPKREGNQYFLALVAK
EEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHEEECCCCCCCEEEEEEEEC
>Mature Secondary Structure
MQVKKNNKNRINGFITAKEVRLVDHSGEMIGIVLIERALELAQGVGLDLVEIAPDSTPPV
CCCCCCCCCCEEEEEEEEEEEEEECCCCEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCE
CKILDYSKQKYDIKKKASEAKKKQKTLTIKEIKLGPNIGDHDYETKLRQARDLLVHGHKI
EHHHCCCCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEE
KVTMRFRGRELINTEVGLEKLERLIRDTEDIAKVELAPKREGNQYFLALVAK
EEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHEEECCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]