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The map label for this gene is znuA [H]

Identifier: 225630613

GI number: 225630613

Start: 958977

End: 959858

Strand: Reverse

Name: znuA [H]

Synonym: WRi_008840

Alternate gene names: 225630613

Gene position: 959858-958977 (Counterclockwise)

Preceding gene: 225630617

Following gene: 225630610

Centisome position: 66.39

GC content: 31.75

Gene sequence:

>882_bases
ATGAGACATTTACTGACTTTTTTTCTATTACTTTCATTTACACTATACTATAATATCGCCTTTTCATCCAATTTAAAAGT
TGTAGCTACAATCAAACCTATCCACTCACTTGTAGCTTCTATTACAGAAGGGATTTTAGAACCGGAATTGCTTGGCTATG
CAACATCTGCGCATAATTATATATTAAAGCCATCTGATGCGAGTAATTTAGAATCAAGTGACGTTATATTTTATGTTGAC
GATAACTTAGAGACGTTTGTTCAAACTTTCGCCAAAAATAATAAAGAACTAGTGCAATTGTCAAAGGCAATCAACCTACT
TCCTACTCGGCCACATTCATTTTCTAGAAAAATTACTCACATTAAAGATGAAAAAGATTTACACATTTGGCTGAGTCCCG
AAAATGCAAAGAGCATGATACTTTCTGTAAGTGCAACATTGTCTAACATAGATAAAGAAAATTCCCATCGATACAACTCT
AATGCAACAAAAGCTATAAAAAAAATAGACCAAGAAGTAAAAGAAATTATGAAAGAACTGAATGATTTTAAAAATCAAAA
ATATATCGTCACTCACGATGCTTATCAATATTTTGAAAAATATTTTGGTTTAAATCACCCAAGTGCCATTCTTTCCATAG
AAGAGGATTCTTACATAGGTATGAGGAGTTTAATGAAGCTAAAAAAGATAATGAAGGAAGAAAACGTTAAATGTATATTT
GCTCATTCACAGGAAGACAGCATAAAGCCTAATGCTCTTTCTAATGACGCAAAAATGGTAGTTCTTGATCCTATTGGATC
AGACATAGAGCCTGGAAAAGATGCATATCTAGCTATAATCAATAACATTGCACAAAATTTTAAGTCTTGTTTTGTTGAGT
AA

Upstream 100 bases:

>100_bases
TTTTACCATCATATGCGAGAGCAAGATTTTCTATTTTTAGAACACGATTATTGACATTATTCAATTTATTGACAAAATTT
AACTTCTTCTCAACGTTTAT

Downstream 100 bases:

>100_bases
TAAGTTCCCTTTTAGCTTACTGTTTTTATTGTTCTGCATTTATTTGTCCTTTACATATTATGCAGGTTTAGAATTATGCT
TTATTCTTACGTTTATGTCT

Product: cation ABC transporter, periplasmic cation-binding protein, putative

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MRHLLTFFLLLSFTLYYNIAFSSNLKVVATIKPIHSLVASITEGILEPELLGYATSAHNYILKPSDASNLESSDVIFYVD
DNLETFVQTFAKNNKELVQLSKAINLLPTRPHSFSRKITHIKDEKDLHIWLSPENAKSMILSVSATLSNIDKENSHRYNS
NATKAIKKIDQEVKEIMKELNDFKNQKYIVTHDAYQYFEKYFGLNHPSAILSIEEDSYIGMRSLMKLKKIMKEENVKCIF
AHSQEDSIKPNALSNDAKMVVLDPIGSDIEPGKDAYLAIINNIAQNFKSCFVE

Sequences:

>Translated_293_residues
MRHLLTFFLLLSFTLYYNIAFSSNLKVVATIKPIHSLVASITEGILEPELLGYATSAHNYILKPSDASNLESSDVIFYVD
DNLETFVQTFAKNNKELVQLSKAINLLPTRPHSFSRKITHIKDEKDLHIWLSPENAKSMILSVSATLSNIDKENSHRYNS
NATKAIKKIDQEVKEIMKELNDFKNQKYIVTHDAYQYFEKYFGLNHPSAILSIEEDSYIGMRSLMKLKKIMKEENVKCIF
AHSQEDSIKPNALSNDAKMVVLDPIGSDIEPGKDAYLAIINNIAQNFKSCFVE
>Mature_293_residues
MRHLLTFFLLLSFTLYYNIAFSSNLKVVATIKPIHSLVASITEGILEPELLGYATSAHNYILKPSDASNLESSDVIFYVD
DNLETFVQTFAKNNKELVQLSKAINLLPTRPHSFSRKITHIKDEKDLHIWLSPENAKSMILSVSATLSNIDKENSHRYNS
NATKAIKKIDQEVKEIMKELNDFKNQKYIVTHDAYQYFEKYFGLNHPSAILSIEEDSYIGMRSLMKLKKIMKEENVKCIF
AHSQEDSIKPNALSNDAKMVVLDPIGSDIEPGKDAYLAIINNIAQNFKSCFVE

Specific function: Involved in the high-affinity zinc uptake transport system. Required for survival and normal growth under low Zn (2+) concentrations. Also required for virulence and intracellular growth in macrophages [H]

COG id: COG4531

COG function: function code P; ABC-type Zn2+ transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=286, Percent_Identity=26.5734265734266, Blast_Score=127, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 33345; Mature: 33345

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHLLTFFLLLSFTLYYNIAFSSNLKVVATIKPIHSLVASITEGILEPELLGYATSAHNY
CHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHEEECCCCE
ILKPSDASNLESSDVIFYVDDNLETFVQTFAKNNKELVQLSKAINLLPTRPHSFSRKITH
EECCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHC
IKDEKDLHIWLSPENAKSMILSVSATLSNIDKENSHRYNSNATKAIKKIDQEVKEIMKEL
CCCCCCEEEEECCCCHHHHEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NDFKNQKYIVTHDAYQYFEKYFGLNHPSAILSIEEDSYIGMRSLMKLKKIMKEENVKCIF
HHHCCCCEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEE
AHSQEDSIKPNALSNDAKMVVLDPIGSDIEPGKDAYLAIINNIAQNFKSCFVE
EECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRHLLTFFLLLSFTLYYNIAFSSNLKVVATIKPIHSLVASITEGILEPELLGYATSAHNY
CHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHHHHHHCCCHHHHHEEECCCCE
ILKPSDASNLESSDVIFYVDDNLETFVQTFAKNNKELVQLSKAINLLPTRPHSFSRKITH
EECCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHC
IKDEKDLHIWLSPENAKSMILSVSATLSNIDKENSHRYNSNATKAIKKIDQEVKEIMKEL
CCCCCCEEEEECCCCHHHHEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
NDFKNQKYIVTHDAYQYFEKYFGLNHPSAILSIEEDSYIGMRSLMKLKKIMKEENVKCIF
HHHCCCCEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEE
AHSQEDSIKPNALSNDAKMVVLDPIGSDIEPGKDAYLAIINNIAQNFKSCFVE
EECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA