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The map label for this gene is pqqL [C]

Identifier: 225630488

GI number: 225630488

Start: 798661

End: 799935

Strand: Direct

Name: pqqL [C]

Synonym: WRi_007380

Alternate gene names: 225630488

Gene position: 798661-799935 (Clockwise)

Preceding gene: 225630487

Following gene: 225630492

Centisome position: 55.24

GC content: 37.1

Gene sequence:

>1275_bases
ATGAATGTACCCCGGGTAACAAAATTAGATAATGGTCTGCGCATAATAACTGAGCAGGTGCGTGATATTGATTCCGTAGC
TTTAAGCATACGAGTTGGTGTTGGCAGTAGAGCAGAAAGTGCAAAGCAAAATGGAATATCCCATTTTTTAGAACACATGG
CTTTCAAAGGGACGAAGACAAGAACTGCCTTTGAAATTGCAAAAGCTTTTGATGACATAGGTGGGGTTTTCAACGCCAGC
ACTGGTAGGGAAAGCACCACCTATTATGCAAAAGTCCTCAAGAAAGACATCAAAACTGGTATTGATATACTAATAGATAT
ATTGATGAATTCAACATTTCCAGAAGATGAATTGGAGCGTGAGAAGGGCGTTGTAATACAAGAGATTTTTCAAACTAATG
ATTCACCAAGTGACATTGTTTTCGATAAATATTTTGAGGCAGCTTATAAAGATCAACCTTTCGGCAGGTCAATCTTAGGC
ACGCAAGATACTGTAAAATCTTTTACTCGAGGAGATCTAGATAATTACATAAATGAGCATTACTTTGGCGAGAATATGCT
ATTTGCCGTTGCAGGAAATGTTGAACATGAAGAAGTTGTTGCATTAACCAAAGATTTTTTCTCAAAGATTCATTCTAAAA
AGCTGAAAAAAAGCCAAAATGCGACGAGCCACACTGGTGGTGAGTATTTAGAACATCGTAAATTAGATCAGGTGCACTTG
CTAATTGGTCTACCTAGTGTTTCTCGCCATGACGATAAATATCACACGTTTCAAGTGCTTGATTCTATATTAGGGAGCGG
AATGTCATCACGTTTATTCCAGGAAGTAAGGGAAAAGCAGGGATTAGCTTATTCTGTTTATTCATTTAATTCCAGCTATA
CTGATACAGGAATGTTTTCCATTTTTGCTGGTACAGACAGTAGTAACTTAGATAAGCTTTTAAAATCTATAACGACAGAG
TTGAAGAAGTTGTCTACAGATGATTTGAGGGAAGAAGAAGTAAATAGAGTGAAAGAGCGAGTAAAATCCCAAATTTTAAT
GTCACGCGAAAGTGTGAGCTCACGTGCTGAAACATTGGGGCACTACTACGGTAACTATAATAGGTACATCAGTAAAAATG
AATTAATAGAAAAAATTAGTGCAGTTACCACTGCTAACGTAAAAAAAGCAGCAGAAGAATTATTATCTCAGCATGAAAAA
GCCACTCTAGCTGCAATTGGAGAAATTAAGTCACTGCCAAGTTACGATAAAGTGGTTTCTATGCTTAAAGCTTAG

Upstream 100 bases:

>100_bases
TTAGATTGTCAAAACCGTAGAATTGACTACATAAAAGTTTTCCTTGATCATTTAATTAATTGGGATTTTGCAGAAGAGAA
TTTAAAAAAGAACACATAAG

Downstream 100 bases:

>100_bases
TGTATTCTGTTATATTGATTTGGCTGCTTTACAATAGATCTTCATAATTTATAGCTAAAGTGACTTAAGTTTACCGATAA
TTTGAAAAACAAAAATTCGT

Product: peptidase, M16 family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MNVPRVTKLDNGLRIITEQVRDIDSVALSIRVGVGSRAESAKQNGISHFLEHMAFKGTKTRTAFEIAKAFDDIGGVFNAS
TGRESTTYYAKVLKKDIKTGIDILIDILMNSTFPEDELEREKGVVIQEIFQTNDSPSDIVFDKYFEAAYKDQPFGRSILG
TQDTVKSFTRGDLDNYINEHYFGENMLFAVAGNVEHEEVVALTKDFFSKIHSKKLKKSQNATSHTGGEYLEHRKLDQVHL
LIGLPSVSRHDDKYHTFQVLDSILGSGMSSRLFQEVREKQGLAYSVYSFNSSYTDTGMFSIFAGTDSSNLDKLLKSITTE
LKKLSTDDLREEEVNRVKERVKSQILMSRESVSSRAETLGHYYGNYNRYISKNELIEKISAVTTANVKKAAEELLSQHEK
ATLAAIGEIKSLPSYDKVVSMLKA

Sequences:

>Translated_424_residues
MNVPRVTKLDNGLRIITEQVRDIDSVALSIRVGVGSRAESAKQNGISHFLEHMAFKGTKTRTAFEIAKAFDDIGGVFNAS
TGRESTTYYAKVLKKDIKTGIDILIDILMNSTFPEDELEREKGVVIQEIFQTNDSPSDIVFDKYFEAAYKDQPFGRSILG
TQDTVKSFTRGDLDNYINEHYFGENMLFAVAGNVEHEEVVALTKDFFSKIHSKKLKKSQNATSHTGGEYLEHRKLDQVHL
LIGLPSVSRHDDKYHTFQVLDSILGSGMSSRLFQEVREKQGLAYSVYSFNSSYTDTGMFSIFAGTDSSNLDKLLKSITTE
LKKLSTDDLREEEVNRVKERVKSQILMSRESVSSRAETLGHYYGNYNRYISKNELIEKISAVTTANVKKAAEELLSQHEK
ATLAAIGEIKSLPSYDKVVSMLKA
>Mature_424_residues
MNVPRVTKLDNGLRIITEQVRDIDSVALSIRVGVGSRAESAKQNGISHFLEHMAFKGTKTRTAFEIAKAFDDIGGVFNAS
TGRESTTYYAKVLKKDIKTGIDILIDILMNSTFPEDELEREKGVVIQEIFQTNDSPSDIVFDKYFEAAYKDQPFGRSILG
TQDTVKSFTRGDLDNYINEHYFGENMLFAVAGNVEHEEVVALTKDFFSKIHSKKLKKSQNATSHTGGEYLEHRKLDQVHL
LIGLPSVSRHDDKYHTFQVLDSILGSGMSSRLFQEVREKQGLAYSVYSFNSSYTDTGMFSIFAGTDSSNLDKLLKSITTE
LKKLSTDDLREEEVNRVKERVKSQILMSRESVSSRAETLGHYYGNYNRYISKNELIEKISAVTTANVKKAAEELLSQHEK
ATLAAIGEIKSLPSYDKVVSMLKA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=434, Percent_Identity=34.331797235023, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI46593007, Length=432, Percent_Identity=28.0092592592593, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI24308013, Length=450, Percent_Identity=26.2222222222222, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI50592988, Length=432, Percent_Identity=24.3055555555556, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1787770, Length=294, Percent_Identity=26.8707482993197, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71999683, Length=428, Percent_Identity=28.2710280373832, Blast_Score=191, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17553678, Length=435, Percent_Identity=26.6666666666667, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17510601, Length=447, Percent_Identity=22.8187919463087, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17569737, Length=427, Percent_Identity=22.7166276346604, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323192, Length=429, Percent_Identity=34.032634032634, Blast_Score=241, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6321813, Length=412, Percent_Identity=25.4854368932039, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319426, Length=446, Percent_Identity=23.3183856502242, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325449, Length=327, Percent_Identity=23.8532110091743, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357875, Length=437, Percent_Identity=32.2654462242563, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI24646943, Length=437, Percent_Identity=32.2654462242563, Blast_Score=245, Evalue=5e-65,
Organism=Drosophila melanogaster, GI19921772, Length=449, Percent_Identity=24.9443207126949, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24665395, Length=402, Percent_Identity=24.8756218905473, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24641429, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24667786, Length=176, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47613; Mature: 47613

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVPRVTKLDNGLRIITEQVRDIDSVALSIRVGVGSRAESAKQNGISHFLEHMAFKGTKT
CCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCH
RTAFEIAKAFDDIGGVFNASTGRESTTYYAKVLKKDIKTGIDILIDILMNSTFPEDELER
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EKGVVIQEIFQTNDSPSDIVFDKYFEAAYKDQPFGRSILGTQDTVKSFTRGDLDNYINEH
HHCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
YFGENMLFAVAGNVEHEEVVALTKDFFSKIHSKKLKKSQNATSHTGGEYLEHRKLDQVHL
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEE
LIGLPSVSRHDDKYHTFQVLDSILGSGMSSRLFQEVREKQGLAYSVYSFNSSYTDTGMFS
EEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEE
IFAGTDSSNLDKLLKSITTELKKLSTDDLREEEVNRVKERVKSQILMSRESVSSRAETLG
EEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HYYGNYNRYISKNELIEKISAVTTANVKKAAEELLSQHEKATLAAIGEIKSLPSYDKVVS
HHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MLKA
HHCC
>Mature Secondary Structure
MNVPRVTKLDNGLRIITEQVRDIDSVALSIRVGVGSRAESAKQNGISHFLEHMAFKGTKT
CCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCH
RTAFEIAKAFDDIGGVFNASTGRESTTYYAKVLKKDIKTGIDILIDILMNSTFPEDELER
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EKGVVIQEIFQTNDSPSDIVFDKYFEAAYKDQPFGRSILGTQDTVKSFTRGDLDNYINEH
HHCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHH
YFGENMLFAVAGNVEHEEVVALTKDFFSKIHSKKLKKSQNATSHTGGEYLEHRKLDQVHL
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEE
LIGLPSVSRHDDKYHTFQVLDSILGSGMSSRLFQEVREKQGLAYSVYSFNSSYTDTGMFS
EEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEE
IFAGTDSSNLDKLLKSITTELKKLSTDDLREEEVNRVKERVKSQILMSRESVSSRAETLG
EEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HYYGNYNRYISKNELIEKISAVTTANVKKAAEELLSQHEKATLAAIGEIKSLPSYDKVVS
HHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
MLKA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA